The DOI matches its Crossref record; 71 of the 71 references it cites were found in a registry or an index.
Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances: Miniperspective
Open accessAbstract
The use of privileged structures in drug discovery has proven to be an effective strategy, allowing the generation of innovative hits/leads and successful optimization processes. Chromone is recognized as a privileged structure and a useful template for the design of novel compounds with potential pharmacological interest, particularly in the field of neurodegenerative, inflammatory, and infectious diseases as well as diabetes and cancer. This perspective provides the reader with an update of an earlier article entitled "Chromone: A Valid Scaffold in Medicinal Chemistry" ( Chem. Rev. 2014 , 114 , 4960 - 4992 ) and is mainly focused on chromones of biological interest, including those isolated from natural sources. Moreover, as drug repurposing is becoming an attractive drug discovery approach, recent repurposing studies of chromone-based drugs are also reported.
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Chromone: A Valid Scaffold in Medicinal Chemistry
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Self-citationKynurenic Acid as a Ligand for Orphan G Protein-coupled Receptor GPR35
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Chromones as a privileged scaffold in drug discovery: A review
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Delost, M. D., Smith, D. T., Anderson, B. J., & Njardarson, J. T. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00876 · Cited by 409
Metadata
- Authors
- Reis, J., Gaspar, A., Milhazes, N., & Borges, F.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2017-06-13
- Volume
- 60
- Issue
- 19
- Pages
- 7941-7957
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W2620296850
- Cited by
- 414
- References
- 71
- FWCI
- 18.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Reis, J., Gaspar, A., Milhazes, N., & Borges, F. (2017). Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances: Miniperspective. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.6b01720
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
