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Cited by 553

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors

Medina-Sánchez, Mariana, Schwarz, Lukas, Meyer, Anne K., Hebenstreit, Franziska, Schmidt, Oliver G.·2016·Nano Letters

Abstract

We present artificially motorized sperm cells-a novel type of hybrid micromotor, where customized microhelices serve as motors for transporting sperm cells with motion deficiencies to help them carry out their natural function. Our results indicate that metal-coated polymer microhelices are suitable for this task due to potent, controllable, and nonharmful 3D motion behavior. We manage to capture, transport, and release single immotile live sperm cells in fluidic channels that allow mimicking physiological conditions. Important steps toward fertilization are addressed by employing proper means of sperm selection and oocyte culturing. Despite the fact that there still remain some challenges on the way to achieve successful fertilization with artificially motorized sperms, we believe that the potential of this novel approach toward assisted reproduction can be already put into perspective with the present work.

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Crossref · 10.1021/acs.nanolett.5b04221

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Metadata

Authors
Medina-Sánchez, M., Schwarz, L., Meyer, A. K., Hebenstreit, F., & Schmidt, O. G.
Venue
Nano Letters
Published
2015-12-23
Volume
16
Issue
1
Pages
555-561
ISSN
  • 1530-6984 (ISSN-L)
  • 1530-6992
OpenAlex
W2234717249
Cited by
553
References
2
FWCI
24.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors. https://app.cochat.ai/papers/10.1021/acs.nanolett.5b04221
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Medina-Sánchez, M., Schwarz, L., Meyer, A. K., Hebenstreit, F., & Schmidt, O. G. (2016). Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors. Nano Letters. https://doi.org/10.1021/acs.nanolett.5b04221

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