A Proposal That Would Ban Manufacture, Supply, and Use of All Fluoropolymers and Most Fluorinated Reagents within the Entire EU
Abstract
A change to EU law is proposed that would lead to a ban on manufacture, supply, and use of most per- and polyfluorinated alkyl substance (PFAS) materials. The proposed EU definition of PFAS is extremely broad, including most fluoroalkyl materials, regardless of molecular weight. Thus, reagents as simple as trifluoroacetic acid through fluorinated intermediates to polymers such as PTFE, PVDF, and Viton could be entirely banned, with the exception of API molecules themselves. The implications of such a ban for the chemical and (bio)pharma industries in Europe cannot be overstated. The EU Proposal is currently out for public consultation, and the purpose of this Perspective is both to raise awareness and to encourage contributions to the consultation process. Comments to the EU must be received by the deadline of 23:59 (Helsinki time) on September 25, 2023 .
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PFAS have persistence, bioaccumulation, and potential toxicity, which has prompted stricter regulations.
“heightened awareness of their persistence, bioaccumulation, and potential toxicity has prompted stricter regulations.23,24”
From PFAS free chemically amplified resists enabled by low activation energy hydrocarbon cage monomers (2026) · cites this paper as [24]
Cites
FDA-Approved Fluorinated Heterocyclic Drugs from 2016 to 2022
Rizzo, C., Amata, S., Pibiri, I., Pace, A., Buscemi, S., & Piccionello, A. P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24097728 · Cited by 99 · see citing works
<scp>ePTFE</scp>‐based biomedical devices: An overview of surgical efficiency
Roina, Y., Auber, F., Hocquet, D., & Herlem, G. (2022) · Journal of Biomedical Materials Research Part B: Applied Biomaterials · doi:10.1002/jbm.b.34928 · Cited by 69 · see citing works
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PFAS free chemically amplified resists enabled by low activation energy hydrocarbon cage monomers
Liu, Y., Summersgill, M. D., Cheng, H.-H., Chow, S., Im, E., Du, Y., Xing, H., Houston, S. D., Nielsen, B., Whittaker, A. K., et al. (2026) · Chemical Science · doi:10.1039/d6sc03643k
- Authors
- Tyrrell, N. D.
- Affiliations
- Almac (United Kingdom) (GB)
- Corresponding author
- Tyrrell, Nicholas D.
- ORCID
- Tyrrell, Nicholas D.
- Venue
- Organic Process Research & Development
- Publisher
- American Chemical Society (ACS)
- Published
- 2023-08-02
- Volume
- 27
- Issue
- 8
- Pages
- 1422-1426
- ISSN
- 1083-6160 (ISSN-L)
- 1520-586X
- OpenAlex
- W4385497587
- Cited by
- 113
- References
- 2
- Citations by year
- 2026: 31 · 2025: 45 · 2024: 28 · 2023: 9
- FWCI
- 9.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Organic Process Research & Development (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Environmental Chemistry › Chemistry and Chemical Engineering
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Fluorine in Organic Chemistry
- Keywords
- per- and polyfluoroalkyl substances, EU chemical regulation, fluorinated polymers, fluorinated reagents, polytetrafluoroethylene, polyvinylidene fluoride, Viton, trifluoroacetic acid, public consultation
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