Polystyrene Nanofiber Materials for Visible-Light-Driven Dual Antibacterial Action via Simultaneous Photogeneration of NO and O2(1Δg)
Abstract
This contribution reports on the preparation, characterization, and biological evaluation of electrospun polystyrene nanofiber materials engineered with a covalently grafted NO photodonor and ionically entangled tetracationic porphyrin and phthalocyanine photosensitizers. These photofunctional materials exhibit an effective and simultaneous photogeneration of two antibacterial species such as nitric oxide (NO) and singlet oxygen, O2((1)Δg) under illumination with visible light, as demonstrated by their direct detection using amperometric and time-resolved spectroscopic techniques. Dual-mode photoantibacterial action is demonstrated by antibacterial tests carried out on Escherichia coli.
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- Authors
- Dolanský, J., Henke, P., Kubát, P., Fraix, A., Sortino, S., & Mosinger, J.
- Affiliations
- Czech Academy of Sciences (CZ)
- Charles University (CZ)
- University of Catania (IT)
- Corresponding author
- Sortino, Salvatore
- Mosinger, Jiří
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-10-12
- Volume
- 7
- Issue
- 41
- Pages
- 22980-22989
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2295644532
- Cited by
- 52
- References
- 49
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 7 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 8 · 2019: 7 · 2018: 7 · 2017: 2 · 2016: 5
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ACS Applied Materials & Interfaces (publishedVersion)
- PubMed (publishedVersion)
- ASEP (submittedVersion, public-domain)
- Funders
- Ministero dell'Istruzione, dell'Università e della Ricerca
- Czech Science Foundation (13-12496S)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Advanced Photocatalysis Techniques
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Keywords
- polystyrene nanofibers, electrospinning, tetracationic porphyrin, phthalocyanines, photosensitizers, singlet oxygen, visible light photocatalysis, Escherichia coli, covalent grafting
- MeSH terms
- Anti-Bacterial Agents, Fluorescence, Ion Exchange, Light, Nitric Oxide, Oxygen, Polystyrenes, Solutions, Spectrophotometry, Ultraviolet, Spectroscopy, Fourier Transform Infrared, Electrochemical Techniques, Nanofibers
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