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Cited by 298

The DOI matches its Crossref record; 249 of the 249 references it cites were found in a registry or an index.

Engineering Hydrogel Adhesion for Biomedical Applications via Chemical Design of the Junction

Open access
Bovone, Giovanni, Dudaryeva, Oksana Y., Marco-Dufort, Bruno, Tibbitt, Mark W.·2021·ACS Biomaterials Science & Engineering

Abstract

Hydrogel adhesion inherently relies on engineering the contact surface at soft and hydrated interfaces. Upon contact, adhesion normally occurs through the formation of chemical or physical interactions between the disparate surfaces. The ability to form these adhesion junctions is challenging for hydrogels as the interfaces are wet and deformable and often contain low densities of functional groups. In this Review, we link the design of the binding chemistries or adhesion junctions, whether covalent, dynamic covalent, supramolecular, or physical, to the emergent adhesive properties of soft and hydrated interfaces. Wet adhesion is useful for bonding to or between tissues and implants for a range of biomedical applications. We highlight several recent and emerging adhesive hydrogels for use in biomedicine in the context of efficient junction design. The main focus is on engineering hydrogel adhesion through molecular design of the junctions to tailor the adhesion strength, reversibility, stability, and response to environmental stimuli.

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Metadata

Authors
Bovone, G., Dudaryeva, O. Y., Marco-Dufort, B., & Tibbitt, M. W.
Venue
ACS Biomaterials Science & Engineering
Published
2021-04-01
Volume
7
Issue
9
Pages
4048-4076
ISSN
2373-9878 (ISSN-L)
OpenAlex
W3152024668
Cited by
298
References
249
FWCI
8.31
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Engineering Hydrogel Adhesion for Biomedical Applications via Chemical Design of the Junction. https://app.cochat.ai/papers/10.1021/acsbiomaterials.0c01677
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Bovone, G., Dudaryeva, O. Y., Marco-Dufort, B., & Tibbitt, M. W. (2021). Engineering Hydrogel Adhesion for Biomedical Applications via Chemical Design of the Junction. ACS Biomaterials Science & Engineering. https://doi.org/10.1021/acsbiomaterials.0c01677

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