Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

Cited by (112)

Items 101–112 of 112

1. PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network
   Reichermeier, Kurt M., Straube, Ronny, Reitsma, Justin M., Sweredoski, Michael J., Rose, Christopher M., Moradian, Annie, den Besten, Willem, Hinkle, Trent, Verschueren, Erik, Petzold, Georg et al. · 2020 · Molecular Cell
2. A novel cereblon modulator for targeted protein degradation
   Kim, Sung Ah, Go, Ara, Jo, Seung-Hyun, Park, Sun Jun, Jeon, Young Uk, Kim, Ji Eun, Lee, Heung Kyoung, Park, Chi Hoon, Lee, Chong-Ock, Park, Sung Goo et al. · 2019 · European Journal of Medicinal Chemistry
3. Hydrophobic tagging-mediated degradation of Alzheimer's disease related Tau
   Gao, Na, Chu, Ting-Ting, Li, Qian-Qian, Lim, Yeh-Jun, Qiu, Tian, Ma, Meng-Rong, Hu, Zhi-Wen, Yang, Xi-Fei, Chen, Yong-Xiang, Zhao, Yu-Fen et al. · 2017 · RSC Advances
4. A critical evaluation of the approaches to targeted protein degradation for drug discovery
   Chopra, Rajesh, Sadok, Amine, Collins, Ian · 2019 · Drug Discovery Today: Technologies
5. Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence
   Duran-Frigola, Miquel, Cigler, Marko, Winter, Georg E. · 2023 · Journal of the American Chemical Society
6. A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
   Payne, N. Connor, Maksoud, Semer, Tannous, Bakhos A., Mazitschek, Ralph · 2022 · Cell Chemical Biology
7. Niedermolekulare PROTACs: neue Wege zum Abbau von Proteinen
   Toure, Momar, Crews, Craig M. · 2016 · Angewandte Chemie
8. Identification and characterization of cancer vulnerabilities via targeted protein degradation
   Mayor-Ruiz, Cristina, Winter, Georg E. · 2019 · Drug Discovery Today: Technologies
9. A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
   Pinch, Benika J., Buckley, Dennis L., Gleim, Scott, Brittain, Scott M., Tandeske, Laura, D'Alessandro, Pier Luca, Hauseman, Zachary J., Lipps, Jennifer, Xu, Lei, Harvey, Edward P. et al. · 2022 · Cell Chemical Biology
10. Targeted protein modification as a paradigm shift in drug discovery
    Amirian, Roshanak, Azadi Badrbani, Mehdi, Izadi, Zhila, Samadian, Hadi, Bahrami, Gholamreza, Sarvari, Sajad, Abdolmaleki, Sara, Nabavi, Seyed Mohammad, Derakhshankhah, Hossein, Jaymand, Mehdi · 2023 · European Journal of Medicinal Chemistry
11. Proteasomal and lysosomal degradation for specific and durable suppression of immunotherapeutic targets
    Wang, Yungang, Deng, Shouyan, Xu, Jie · 2020 · Cancer Biology and Medicine
12. Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange
    Dixon, Tom, MacPherson, Derek, Mostofian, Barmak, Dauzhenka, Taras, Lotz, Samuel, McGee, Dwight, Shechter, Sharon, Shrestha, Utsab R., Wiewiora, Rafal, McDargh, Zachary A. et al. · 2021