The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts
Abstract
Abstract Single-atom catalysts (SACs) featuring the complete atomic utilization of metal, high-efficient catalytic activity, superior selectivity, and excellent stability have been emerged as a frontier in the catalytic field. Recently, increasing interests have been drawn to apply SACs in biomedical fields for enzyme-mimic catalysis and disease therapy. To fulfill the demand of precision and personalized medicine, precisely engineering the structure and active site toward atomic levels is a trend for nanomedicines, promoting the evolution of metal-based biomedical nanomaterials, particularly biocatalytic nanomaterials, from nanoparticles to clusters and now to SACs. This review outlines the syntheses, characterizations, and catalytic mechanisms of metal clusters and SACs, with a focus on their biomedical applications including biosensing, antibacterial therapy, and cancer therapy, as well as an emphasis on their in vivo biological safeties. Challenges and future perspectives are ultimately prospected for SACs in diverse biomedical applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Self-citationTargeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2803 · Cited by 5,452
Multifunctional Magnetic Nanoparticles: Design, Synthesis, and Biomedical Applications
Gao, J., Gu, H., & Xu, B. (2009) · Accounts of Chemical Research · doi:10.1021/ar9000026 · Cited by 1,907
Cell Membrane Coating Nanotechnology
Fang, R. H., Kroll, A. V., Gao, W., & Zhang, L. (2018) · Advanced Materials · doi:10.1002/adma.201706759 · Cited by 1,885
An overview of nanoparticles commonly used in fluorescent bioimaging
Wolfbeis, O. S. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00392f · Cited by 1,631
Catalysis by Supported Single Metal Atoms
Liu, J. (2017) · ACS Catalysis · doi:10.1021/acscatal.6b01534 · Cited by 1,331
Block copolymer micelles in nanomedicine applications
Cabral, H., Miyata, K., Osada, K., & Kataoka, K. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00199 · Cited by 1,309
Next-generation in vivo optical imaging with short-wave infrared quantum dots
Bruns, O. T., Bischof, T. S., Harris, D. K., Franke, D., Shi, Y., Riedemann, L., Bartelt, A., Jaworski, F. B., Carr, J. A., Rowlands, C. J., et al. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0056 · Cited by 686
Single-atom Rh/N-doped carbon electrocatalyst for formic acid oxidation
Xiong, Y., Dong, J., Huang, Z.-Q., Xin, P., Chen, W., Wang, Y., Li, Z., Jin, Z., Xing, W., Zhuang, Z., et al. (2020) · Nature Nanotechnology · doi:10.1038/s41565-020-0665-x · Cited by 610
Ji, J., Zhang, Y., Tang, L., Liu, C., Gao, X., Sun, M., Zheng, J., Ling, M., Liang, C., & Lin, Z. (2019) · Nano Energy · doi:10.1016/j.nanoen.2019.06.045 · Cited by 164
Cited by
Porous organic polymers as a platform for sensing applications
Wang, S., Li, H., Huang, H., Cao, X., Chen, X., & Cao, D. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00059h · Cited by 363
Wang, W., Cui, Y., Wei, X., Zang, Y., Chen, X., Cheng, L., & Wang, X. (2024) · ACS Nano · doi:10.1021/acsnano.4c02825 · Cited by 303
Chemical Flexibility of Atomically Precise Metal Clusters
Li, S., Li, N.-N., Dong, X.-Y., Zang, S.-Q., & Mak, T. C. W. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00896 · Cited by 280
Dai, S., Jiang, L., Liu, L., Su, Z., Yao, L., Yang, P., & Huang, N. (2024) · Regenerative Biomaterials · doi:10.1093/rb/rbae119 · Cited by 43
Metadata
- Authors
- Fan, Y., Liu, S., Yi, Y., Rong, H., & Zhang, J.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2021-02-10
- Volume
- 15
- Issue
- 2
- Pages
- 2005-2037
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W3127120089
- Cited by
- 276
- References
- 10
- FWCI
- 13.74
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts. https://app.cochat.ai/papers/10.1021/acsnano.0c06962
- The paper
- Fan, Y., Liu, S., Yi, Y., Rong, H., & Zhang, J. (2021). Catalytic Nanomaterials toward Atomic Levels for Biomedical Applications: From Metal Clusters to Single-Atom Catalysts. ACS Nano. https://doi.org/10.1021/acsnano.0c06962
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
