On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
Kulkarni, Jayesh A., Darjuan, Maria M., Mercer, Joanne E., Chen, Sam, van der Meel, Roy, Thewalt, Jenifer L., Tam, Yuen Yi C., Cullis, Pieter R.·2018·ACS Nano
Cited by (662)
Items 101–200 of 662
- Targeted Delivery of Doxorubicin Liposomes for Her-2+ Breast Cancer TreatmentNusrat Chowdhury, Shanzay Chaudhry, Nicholas Hall, George Olverson, Qian-Jin Zhang, Tarun K. Mandal, Srikanta Dash, Anup K. Kundu · 2020 · AAPS PharmSciTech
- mRNA lipid nanoparticle phase transitionMarius F.W. Trollmann, Rainer A. Böckmann · 2022 · Biophysical Journal
- The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropismDaria M. Strelkova Petersen, Namit Chaudhary, Mariah Lynn Arral, Ryan M. Weiss, Kathryn A. Whitehead · 2023 · European Journal of Pharmaceutics and Biopharmaceutics
- Nanoparticle-Based Phototriggered Cancer Immunotherapy and Its Domino Effect in the Tumor MicroenvironmentSanthosh Kalash Rajendrakumar, Saji Uthaman, Chong-Su Cho, In‐Kyu Park · 2018 · Biomacromolecules
- Effect of Lipid Nanoparticle Physico-Chemical Properties and Composition on Their Interaction with the Immune SystemLaura Catenacci, Rachele Rossi, Francesca Sechi, Daniela Buonocore, Milena Sorrenti, Sara Perteghella, Marco Peviani, Maria Cristina Bonferoni · 2024 · Pharmaceutics
- Recent Advances in the use of Fluorescent Nanoparticles for BioimagingFeby Wijaya Pratiwi, Chiung Wen Kuo, Bi‐Chang Chen, Peilin Chen · 2019 · Nanomedicine
- Light-Activated siRNA Endosomal Release (LASER) by Porphyrin Lipid NanoparticlesYulin Mo, Miffy H. Y. Cheng, Andrew D’Elia, Katie Doran, Lili Ding, Juan Chen, Pieter R. Cullis, Gang Zheng · 2023 · ACS Nano
- Cancer Nanovaccines: Nanomaterials and Clinical PerspectivesNimeet Desai, Vivek P. Chavda, Thakur Raghu Raj Singh, Nanasaheb D. Thorat, Lalitkumar K. Vora · 2024 · Small
- Mechanistic Studies of an Automated Lipid Nanoparticle Reveal Critical Pharmaceutical Properties Associated with Enhanced mRNA Functional Delivery In Vitro and In VivoLili Cui, Morag Rose Hunter, Silvia Sonzini, Sara G. T. Pereira, Steven M. Romanelli, Kai Liu, Weimin Li, Lihuan Liang, Bin Yang, Najet Mahmoudi et al. · 2021 · Small
- Understanding molecular mechanisms of biologics drug delivery and stability from NMR spectroscopyPyae Phyo, Xi Rong Zhao, Allen C. Templeton, Wei Xu, Jason K. Cheung, Yongchao Su · 2021 · Advanced Drug Delivery Reviews
- Overcoming doxorubicin resistance in cancer: siRNA-loaded nanoarchitectures for cancer gene therapyMahshid Deldar Abad Paskeh, Hamidreza Saebfar, Mahmood Khaksary Mahabady, Sima Orouei, Kiavash Hushmandi, Maliheh Entezari, Mehrdad Hashemi, Amir Reza Aref, Michael Richard Hamblin, Hui Li Ang et al. · 2022 · Life Sciences
- Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent MannerThijs Van de Vyver, Bram Bogaert, Lynn De Backer, Freya Joris, Roberta Guagliardo, Jelter Van Hoeck, Pieterjan Merckx, Serge Van Calenbergh, Srinivas Ramishetti, Dan Peer et al. · 2020 · ACS Nano
- Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet MixingMatthew N. O’Brien, Antonio P. Costa, Yareli Maciel Cebrero, Johnson Joseph, Apoorva Sarode, Nanzhi Zang, Lee Joon Kim, Kate Hofmann, Shirley Wang, Alexandre Goyon et al. · 2023 · Molecular Pharmaceutics
- Enzyme-Catalyzed One-Step Synthesis of Ionizable Cationic Lipids for Lipid Nanoparticle-Based mRNA COVID-19 VaccinesZhongyu Li, Xue‐Qing Zhang, William Ho, Fengqiao Li, Mingzhu Gao, Xin Bai, Xiaoyang Xu · 2022 · ACS Nano
- Cytotoxic effects of nanoparticles assessed in vitro and in vivo.Kyung Eun Cha, Heejoon Myung · 2007 · PubMed
- Surface engineering of lipid nanoparticles: targeted nucleic acid delivery and beyondYi Lin, Qiang Cheng, Tuo Wei · 2023 · Biophysics Reports
- Liposomal lipid nanoparticles for extrahepatic delivery of mRNAMiffy H. Y. Cheng, Yao Zhang, Kevin Fox, Jerry Leung, Colton Strong, Emma Kang, Yihang Chen, Michelle Tong, Hemashree Bommadevara, Eric Jan et al. · 2025 · Nature Communications
- Acidification-Induced Structure Evolution of Lipid Nanoparticles Correlates with Their In Vitro Gene TransfectionsZongyi Li, Jessica Carter, Luis Santos, Carl I. Webster, Christopher F. van der Walle, Peixun Li, Sarah E. Rogers, Jian Ren Lu · 2023 · ACS Nano
- Looking Back, Moving Forward: Lipid Nanoparticles as a Promising Frontier in Gene DeliveryDaniela Pozzi, Giulio Caracciolo · 2023 · ACS Pharmacology & Translational Science
- Spontaneous, solvent-free entrapment of siRNA within lipid nanoparticlesJayesh A. Kulkarni, Sarah B. Thomson, Josh Zaifman, Jerry Leung, Pamela K. Wagner, Austin M. Hill, Yuen Yi C. Tam, Pieter R. Cullis, Terri L. Petkau, Blair R. Leavitt · 2020 · Nanoscale
- Improved multidetector asymmetrical-flow field-flow fractionation method for particle sizing and concentration measurements of lipid-based nanocarriers for RNA deliveryRobert Mildner, Sjoerd Hak, Jérémie Parot, Astrid Hyldbakk, Sven Even Borgos, Dan Some, Christoph Johann, Fanny Caputo · 2021 · European Journal of Pharmaceutics and Biopharmaceutics
- The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in VivoAfsane Radmand, Melissa P. Lokugamage, Hyejin Kim, Curtis N. Dobrowolski, Ryan Zenhausern, David Loughrey, Sebastian G. Huayamares, Marine Z. C. Hatit, Huanzhen Ni, Ada Del Cid et al. · 2023 · Nano Letters
- A preparation method for mRNA-LNPs with improved propertiesCong Geng, Kefan Zhou, Yan Yan, Chan Li, Beibei Ni, Jiangman Liu, Yeming Wang, Xiaoyan Zhang, Dazhuang Wang, Lu Lv et al. · 2023 · Journal of Controlled Release
- Lipid shape and packing are key for optimal design of pH-sensitive mRNA lipid nanoparticlesGiulio Tesei, Ya‐Wen Hsiao, Aleksandra P. Dabkowska, Gunnar Grönberg, Marianna Yanez Arteta, David Ulkoski, David J. Bray, Martin Trulsson, Johan Ulander, Mikael Lund et al. · 2024 · Proceedings of the National Academy of Sciences
- Non-viral nanoparticles for RNA interference: Principles of design and practical guidelinesZehua Liu, Shiqi Wang, Christos Tapeinos, Giulia Torrieri, Voitto Känkänen, Nesma El‐Sayed, André Python, Jouni J. Hirvonen, Hélder A. Santos · 2021 · Advanced Drug Delivery Reviews
- Size and Charge Characterization of Lipid Nanoparticles for mRNA VaccinesCamille Malburet, Laurent Leclercq, Jean‐François Cotte, Jérôme Thiebaud, Emilie Bazin, Marie Garinot, Hervé Cottet · 2022 · Analytical Chemistry
- Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid NanoparticlesMichael I. Henderson, Yulia Eygeris, Antony Jozić, Marco Herrera‐Barrera, Gaurav Sahay · 2022 · Molecular Pharmaceutics
- Investigating the stability of RNA-lipid nanoparticles in biological fluids: Unveiling its crucial role for understanding LNP performanceHeyang Zhang, Matthias Barz · 2025 · Journal of Controlled Release
- Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug DeliveryRoy van der Meel, Sam Chen, Josh Zaifman, Jayesh A. Kulkarni, Xu Ran S. Zhang, Ying K. Tam, Marcel B. Bally, Raymond Michel Schiffelers, Marco A. Ciufolini, Pieter R. Cullis et al. · 2021 · Small
- Nanoparticles-Based Strategies to Improve the Delivery of Therapeutic Small Interfering RNA in Precision OncologyJinxing Huang, Kai Xiao · 2022 · Pharmaceutics
- Overcoming the Blood–Brain Barrier: Advanced Strategies in Targeted Drug Delivery for Neurodegenerative DiseasesHan‐Mo Yang · 2025 · Pharmaceutics
- Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineeringMarshall Scott Padilla, Kaitlin Mrksich, Yiming Wang, Rebecca M. Haley, Jacqueline J. Li, Emily Laura Han, Rakan D. El-Mayta, Emily H. Kim, Sofia Dias, Ningqiang Gong et al. · 2025 · Nature Communications
- Structure and Morphology of Lipid Nanoparticles for Nucleic Acid Drug Delivery: A ReviewAniket Pradip Udepurkar, Cedric Devos, Peter Sagmeister, Francesco Destro, Pavan Inguva, Soroush Ahmadi, Étienne Boulais, Yufeng Quan, Richard D. Braatz, Allan S. Myerson · 2025 · ACS Nano
- Lipid‐based nanoparticles as drug delivery systems for cancer immunotherapyYang Hao, Zhong‐Hao Ji, Hengzong Zhou, Dongrun Wu, Zili Gu, Dongxu Wang, Peter ten Dijke · 2023 · MedComm
- Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stabilityJennifer Gilbert, Federica Sebastiani, Marianna Yanez Arteta, Ann E. Terry, Anna Fornell, Robert A. Russell, Najet Mahmoudi, Tommy Nylander · 2024 · Journal of Colloid and Interface Science
- Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticlesYuchen Fan, Chun‐Wan Yen, Hsiu-Chao Lin, Weijia Hou, Alberto Estevez, Apoorva Sarode, Alexandre Goyon, Juan Bian, Jessica Lin, Stefan G. Koenig et al. · 2021 · International Journal of Pharmaceutics
- Review of machine learning for lipid nanoparticle formulation and process developmentPhillip James Dorsey, Christina L. Lau, Ti‐chiun Chang, Peter C. Doerschuk, Suzanne M. D’Addio · 2024 · Journal of Pharmaceutical Sciences
- Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutidePhilipp Uhl, Claudia Grundmann, Max Sauter, Philip Storck, Anja Tursch, Suat Özbek, Karin Leotta, Raphael Roth, Dominik Witzigmann, Jayesh A. Kulkarni et al. · 2019 · Nanomedicine Nanotechnology Biology and Medicine
- Recent Update on siRNA TherapeuticsOluwakemi Ebenezer, Abel Kolawole Oyebamiji, John Oludele Olanlokun, Jack A. Tuszyński, Gane Ka‐Shu Wong · 2025 · International Journal of Molecular Sciences
- Monolignol export by diffusion down a polymerization-induced concentration gradientM. Perkins, Mathias Schuetz, Faride Unda, Kent T. J. Chen, Marcel B. Bally, Jayesh A. Kulkarni, Yifan Yan, Joana Pico, Simone Diego Castellarin, Shawn D. Mansfield et al. · 2022 · The Plant Cell
- Nucleic Acid-Loaded Lipid Nanoparticle Interactions with Model Endosomal MembranesAlice Spadea, Mark J. Jackman, Lili Cui, Sara G. T. Pereira, Margaret Jayne Lawrence, Richard A. Campbell, Marianne B. Ashford · 2022 · ACS Applied Materials & Interfaces
- A comparative study on micelles, liposomes and solid lipid nanoparticles for paclitaxel deliveryShradha Dattani, Xiaoling Li, Charina Lampa, David Lechuga‐Ballesteros, Amanda Barriscale, Behzad Damadzadeh, Bhaskara Jasti · 2022 · International Journal of Pharmaceutics
- Comparative study of lipid nanoparticle-based mRNA vaccine bioprocess with machine learning and combinatorial artificial neural network-design of experiment approachRavi Maharjan, Shavron Hada, Ji‐Eun Lee, Hyo-Kyung Han, Ki Hyun Kim, Hye Jin Seo, Camilla Foged, Seong Hoon Jeong · 2023 · International Journal of Pharmaceutics
- Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA DeliveryKim, Jeonghwan, Jozic, Antony, Sahay, Gaurav · 2020 · Cellular and Molecular Bioengineering
- Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying lengthKaitlin Mrksich, Marshall Scott Padilla, Ryann A. Joseph, Emily Laura Han, Dongyoon Kim, Rohan Palanki, Junchao Xu, Michael J. Mitchell · 2024 · Journal of Biomedical Materials Research Part A
- pH-Dependent Phase Behavior and Stability of Cationic Lipid–mRNA NanoparticlesNicholas R. Larson, Gang Hu, Yangjie Wei, Anthony D. Tuesca, Marcus Laird Forrest, Charles Russell Middaugh · 2021 · Journal of Pharmaceutical Sciences
- Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery NanoparticlesAlbert Kamanzi, Yifei Gu, Radin Tahvildari, Zachary Friedenberger, Xingqi Zhu, Romain Berti, Marty Kurylowicz, Dominik Witzigmann, Jayesh A. Kulkarni, Jerry Leung et al. · 2021 · ACS Nano
- Enhancing the Effectiveness of Oligonucleotide Therapeutics Using Cell-Penetrating Peptide Conjugation, Chemical Modification, and Carrier-Based Delivery StrategiesSaeed Anwar, Farin Mir, Toshifumi Yokota · 2023 · Pharmaceutics
- Density Matching Multi-wavelength Analytical Ultracentrifugation to Measure Drug Loading of Lipid Nanoparticle FormulationsAmy Henrickson, Jayesh A. Kulkarni, Josh Zaifman, Gary E. Gorbet, Pieter R. Cullis, Borries Demeler · 2021 · ACS Nano
- RNA vaccines for cancer: Principles to practicePablo Guasp, Charlotte Reiche, Zachary M. Sethna, Vinod P. Balachandran · 2024 · Cancer Cell
- Lipid-Nucleic Acid Complexes: Physicochemical Aspects and Prospects for Cancer TreatmentRicardo Gaspar, Filipe Coelho, Bruno F. B. Silva · 2020 · Molecules
- Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNAXuemei Ge, Lijuan Chen, Bo Zhao, Weien Yuan · 2021 · Frontiers in Pharmacology
- Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus DendrimersJuncheng Lu, Elena N. Atochina‐Vasserman, Devendra S. Maurya, Dipankar Sahoo, Nathan A. Ona, Erin K. Reagan, Houping Ni, Drew Weissman, Virgil Percec · 2023 · Journal of the American Chemical Society
- PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s diseaseEva L. Morozko, Charlene Smith-Geater, Alejandro Mas Monteys, Subrata Pradhan, Ryan G. Lim, Peter Langfelder, Marketta Kachemov, Jayesh A. Kulkarni, Josh Zaifman, Austin M. Hill et al. · 2021 · Proceedings of the National Academy of Sciences
- Harnessing the Therapeutic Potential of Biomacromolecules through Intracellular Delivery of Nucleic Acids, Peptides, and ProteinsYu Ping Tian, Matthew Tirrell, James L. LaBelle · 2022 · Advanced Healthcare Materials
- Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer TherapySepideh Mirzaei, Mohammad Hossein Gholami, Hui Li Ang, Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Kiavash Hushmandi, Masoud Delfi, Haroon Zaman Khan, Milad Ashrafizadeh et al. · 2021 · Cells
- Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver diseaseWoitok, Marius Maximilian, Zoubek, Miguel Eugenio, Doleschel, Dennis, Bartneck, Matthias, Mohamed, Mohamed Ramadan, Kießling, Fabian, Lederle, Wiltrud, Trautwein, Christian, Cubero, Francisco Javier · 2020 · Cell Death & Disease
- Phospholipid Membranes as Chemically and Functionally Tunable MaterialsDaniel Huster, Sudipta Maiti, Andreas Herrmann · 2024 · Advanced Materials
- Exploring precision treatments in immune‐mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid deliveryLingxiao Xu, Zhenxuan Shao, Xia Fang, Zengfeng Xin, Shenzhi Zhao, Hongbo Zhang, Yu Zhang, Wenbiao Zheng, Xiaohua Yu, Zengjie Zhang et al. · 2024 · Exploration
- Rational Design of Lipid Nanoparticles for Enhanced mRNA Vaccine Delivery via Machine LearningSeo‐Hyeon Bae, Hosam Choi, Jisun Lee, Min‐Ho Kang, Seong‐Ho Ahn, Yu‐Sun Lee, Huijeong Choi, Sohee Jo, Yeeun Lee, Hyo‐Jung Park et al. · 2024 · Small
- Characterization of lipid-based nanomedicines at the single-particle levelChaoxiang Chen, Chen Chen, Yurou Li, Ruilan Gu, Xiaomei Yan · 2022 · Fundamental Research
- Inverse Cubic and Hexagonal Mesophase Evolution within Ionizable Lipid Nanoparticles Correlates with mRNA Transfection in MacrophagesHaitao Yu, Joshua Iscaro, Brendan Dyett, Yiran Zhang, Susanne Seibt, Natalia P. Martínez, John White, Calum John Drummond, Steven Bozinovski, Jiali Zhai · 2023 · Journal of the American Chemical Society
- Cell type–specific microRNA therapies for myocardial infarctionLiu, Bohao, Wang, Bryan, Zhang, Xiaokan, Lock, Roberta, Nash, Trevor, Vunjak-Novakovic, Gordana · 2021 · Science Translational Medicine
- Modulating intracellular pathways to improve non-viral delivery of RNA therapeuticsThijs Van de Vyver, Stefaan C. De Smedt, Koen Raemdonck · 2021 · Advanced Drug Delivery Reviews
- Design Strategies for and Stability of mRNA–Lipid Nanoparticle COVID-19 VaccinesTing Liu, Yang Tian, Aiping Zheng, Chunying Cui · 2022 · Polymers
- Bridging Smart Nanosystems with Clinically Relevant Models and Advanced Imaging for Precision Drug DeliveryQiaoxia Zhou, Qiongliang Liu, Yan Wang, Jie Chen, Otmar Schmid, Markus Rehberg, Lin Yang · 2024 · Advanced Science
- Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene deliverySerena Renzi, Luca Digiacomo, Daniela Pozzi, Erica Quagliarini, Elisabetta Vulpis, Maria Valeria Giuli, Angelica Mancusi, Bianca Natiello, Maria Gemma Pignataro, Gianluca Canettieri et al. · 2024 · Nature Communications
- Metabolic Stability and Targeted Delivery of Oligonucleotides: Advancing RNA Therapeutics Beyond The LiverPuneet Anand, Yu Zhang, Suraj Patil, Keerat Kaur · 2025 · Journal of Medicinal Chemistry
- Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene DeliveryErica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Wilfried Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui et al. · 2021 · Pharmaceutics
- Role of drug delivery technologies in the success of COVID-19 vaccines: a perspectiveHagar I. Labouta, Róbert Langer, Pieter R. Cullis, Olivia M. Merkel, Mark R. Prausnitz, Yasmine A. Gomaa, Sara S. Nogueira, Tushar Kumeria · 2022 · Drug Delivery and Translational Research
- The journey of a lifetime — development of Pfizer’s COVID-19 vaccineChelsea R. Thorn, Divya Sharma, Rodney G. Combs, Sonal V. Bhujbal, Jennifer Romine, Xiaolu Zheng, Khurram Sunasara, Advait V. Badkar · 2022 · Current Opinion in Biotechnology
- Nonviral delivery systems for antisense oligonucleotide therapeuticsSi Qin Huang, Xinyan Hao, Yongjiang Li, Junyong Wu, Daxiong Xiang, Shilin Luo · 2022 · Biomaterials Research
- Analytical techniques for the characterization of nanoparticles for mRNA deliverySara S. Nogueira, Eleni Samaridou, Johanna Simon, Frank Simon, Moritz Beck‐Broichsitter, Aditi Mehta · 2024 · European Journal of Pharmaceutics and Biopharmaceutics
- Nanoplatform‐Based In Vivo Gene Delivery Systems for Cancer TherapyRui Luo, Hao Le, Qinjie Wu, Changyang Gong · 2024 · Small
- Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA deliveryMd. Anamul Haque, Archana Shrestha, Constantinos Marios Mikelis, George Mattheolabakis · 2024 · International Journal of Pharmaceutics X
- Nanoscopy for endosomal escape quantificationTeodora Andrian, Roger Riera, Sílvia Pujals, Lorenzo Albertazzi · 2020 · Nanoscale Advances
- Advances in the design and delivery of RNA vaccines for infectious diseasesAbhijeet Girish Lokras, Thomas Rønnemoes Bobak, Saahil Sandeep Baghel, Federica Sebastiani, Camilla Foged · 2024 · Advanced Drug Delivery Reviews
- Development of Lipidoid Nanoparticles for siRNA Delivery to Neural CellsPurva Khare, Kandarp M. Dave, Yashika S. Kamte, Muthiah Manoharan, Lauren A. O’Donnell, Devika Soundara Manickam · 2021 · The AAPS Journal
- Ionizable Amino Lipids Distribution and Effects on DSPC/Cholesterol Membranes: Implications for Lipid Nanoparticle StructureSepehr Dehghani‐Ghahnaviyeh, Michael Smith, Yan Xia, Athanasios D. Dousis, Alan M. Grossfield, Sreyoshi Sur · 2023 · The Journal of Physical Chemistry B
- Morphological Characterization of Self-Amplifying mRNA Lipid NanoparticlesJacob L. Thelen, Wellington Claiton Leite, Volker S. Urban, Hugh O’Neill, Alexander Grishaev, Joseph E. Curtis, Susan Krueger, Maria Monica Castellanos · 2024 · ACS Nano
- Tailoring lipid nanoparticle dimensions through manufacturing processesCaitlin McMillan, Amy Druschitz, Stephen J. Rumbelow, Ankita Borah, Burcu Binici, Zahra Rattray, Yvonne Perrie · 2024 · RSC Pharmaceutics
- More than a delivery system: the evolving role of lipid-based nanoparticlesSenjuti Karmaker, Plinio D. Rosales, Barath Tirumuruhan, Amartya Viravalli, Natalie Boehnke · 2025 · Nanoscale
- Mechanism of pH-sensitive Amphiphilic Endosomal Escape of Ionizable Lipid Nanoparticles for Cytosolic Nucleic Acid DeliveryZheng‐Rong Lu, Da Sun · 2025 · Pharmaceutical Research
- Exploring Mechanisms of Lipid Nanoparticle‐Mucus Interactions in Healthy and Cystic Fibrosis ConditionsBelal Tafech, Mohammad‐Reza Rokhforouz, Jerry Leung, Molly M. H. Sung, Paulo J.C. Lin, Don D. Sin, Daniel Christian Lauster, Stephan Block, Bradley S. Quon, Ying K. Tam et al. · 2024 · Advanced Healthcare Materials
- On the mechanism of tissue-selective gene delivery by lipid nanoparticlesSeigo Kimura, Hideyoshi Harashima · 2023 · Journal of Controlled Release
- The dynamic process of mRNA delivery by lipid nanoparticles in vivoRunpu Ma, Yuting Li, Yi Wei, Juanjuan Zhou, Jinya Ma, Mengke Zhang, Junyi Tu, Jinhong Jiang, Sitao Xie, Weihong Tan et al. · 2024 · Nano Today
- Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseasesSeyedeh Ghazal Moosavi, Niloufar Rahiman, Mahmoud Reza Jaafari, Leila Arabi · 2025 · Journal of Controlled Release
- Lipid-siRNA Organization Modulates the Intracellular Dynamics of Lipid NanoparticlesYulin Mo, Alexander F. A. Keszei, Shagun Kothari, Heyi Liu, Anni Pan, Paige Kim, Jiachuan Bu, Albert Kamanzi, David L. Dai, Mohammad T. Mazhab‐Jafari et al. · 2025 · Journal of the American Chemical Society
- Engineered multi-domain lipid nanoparticles for targeted deliveryZhaoyu Liu, Jingxun Chen, Mingkun Xu, Sherwin Ho, Yuanyuan Wei, Ho‐Pui Ho, Ken‐Tye Yong · 2025 · Chemical Society Reviews
- Development of in silico methodology for siRNA lipid nanoparticle formulationsHaoshi Gao, Stanislav Kan, Zhuyifan Ye, Yuchen Feng, Lei Jin, Xudong Zhang, Jiayin Deng, Ging Chan, Yuanjia Hu, Yongjun Wang et al. · 2022 · Chemical Engineering Journal
- Lipid nanoparticle formulations for optimal RNA-based topical delivery to murine airwaysA Tam, Jayesh A. Kulkarni, Kevin An, L Li, Delbert R. Dorscheid, Gurpreet Kaur Singhera, Pascal N. Bernatchez, Gregor S. D. Reid, Karen Y. T. Chan, Dominik Witzigmann et al. · 2022 · European Journal of Pharmaceutical Sciences
- Lipid nanoparticles as the drug carrier for targeted therapy of hepatic disordersRunxuan Chu, Yi Wang, Jianglong Kong, Ting Shuang Pan, Yani Yang, Jun Feng He · 2024 · Journal of Materials Chemistry B
- Lipid nanoparticle‐mediated RNA delivery for immune cell modulationEmily H. Kim, Sridatta V. Teerdhala, Marshall Scott Padilla, Ryann A. Joseph, Jacqueline J. Li, Rebecca M. Haley, Michael J. Mitchell · 2024 · European Journal of Immunology
- Computational and Experimental Approaches to Investigate Lipid Nanoparticles as Drug and Gene Delivery SystemsChun Chan, Shi Du, Yizhou Dong, Xiaolin Cheng · 2020 · Current Topics in Medicinal Chemistry
- Atomistic Insights into Organization of RNA-Loaded Lipid NanoparticlesMarkéta Paloncýová, Martin Šrejber, Petra Čechová, Petra Kührová, Filip Zaoral, Michal Otyepka · 2023 · The Journal of Physical Chemistry B
- Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNAHiroki Tanaka, Shinya Hagiwara, Daiki Shirane, Takuma Yamakawa, Yuka Sato, Chika Matsumoto, Kota Ishizaki, Miho Hishinuma, Katsuyuki Chida, Kasumi Sasaki et al. · 2023 · ACS Nano
- The emerging potential of siRNA nanotherapeutics in treatment of arthritisAnjali Kumari, Amanpreet Kaur, Geeta Aggarwal · 2023 · Asian Journal of Pharmaceutical Sciences
- Understanding the effects of ethanol on the liposome bilayer structure using microfluidic-based time-resolved small-angle X-ray scattering and molecular dynamics simulationsMasatoshi Maeki, Niko Kimura, Yuto Okada, Kazuki Shimizu, Kana Shibata, Yusuke Miyazaki, Akihiko Ishida, Kento Yonezawa, Nobutaka Shimizu, Wataru Shinoda et al. · 2024 · Nanoscale Advances
- Computational Insights into the Role of Cholesterol in Inverted Hexagonal Phase Stabilization and Endosomal Drug ReleaseMohsen Ramezanpour, D. Peter Tieleman · 2022 · Langmuir
- Clinical Pharmacokinetics of Approved RNA TherapeuticsSeong Jun Jo, Soon Uk Chae, Chae Bin Lee, Soo Kyung Bae · 2023 · International Journal of Molecular Sciences