On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
Kulkarni, Jayesh A., Darjuan, Maria M., Mercer, Joanne E., Chen, Sam, van der Meel, Roy, Thewalt, Jenifer L., Tam, Yuen Yi C., Cullis, Pieter R.·2018·ACS Nano
Cited by (662)
Items 401–500 of 662
- A Comprehensive Dataset of Lipid Nanoparticle Compositions and Properties for Nucleic Acid DeliverySeunghun Song, Jueun Baek, Sangjae Seo · 2025 · Scientific Data
- Synthesis and bioactivity of a novel surfactin-based lipopeptide for mRNA deliveryMohammed S. Alqahtani, Rabbani Syed, Ali S. Alqahtani, Omer Mohammed Almarfadi, Monzurul Amin Roni, Satya Sai Sadhu · 2024 · Nanoscale Advances
- Advanced Nanotechnology-Based Nucleic Acid MedicinesNoriko Miyamoto, Mina Sakuragi, Yukio Kitade · 2024 · Pharmaceutics
- Unlocking the full therapeutic potential of lipid nanoparticles through extrahepatic deliveryHoang Quan Truong, Fanfei Meng · 2025 · Nano Research
- Advances in the Functionalization of Vaccine Delivery Systems: Innovative Strategies and Translational PerspectivesIngrid Andrêssa de Moura, Anna Jéssica Duarte Silva, Larissa Silva de Macêdo, Karina Mayumi Tani Bezerra de Melo, Lígia Rosa Sales Leal, Benigno Cristofer Flores Espinoza, Maria da Conceição Viana Invenção, Samara Sousa de Pinho, Antônio Carlos de Freitas · 2025 · Pharmaceutics
- In Silico Study of Ionizable Lipid Nanoparticles Using the SPICA Force FieldAkhil Pratap Singh, Hiroki Tanaka, Yusuke Miyazaki, Shusaku Nagano, Wataru Shinoda · 2025 · Journal of Chemical Theory and Computation
- Lipid Nanoparticle Development for A Fluvid mRNA Vaccine Targeting Seasonal Influenza and SARS-CoV-2Jiin H. Felgner, Jenny E. Hernandez‐Davies, Erwin Strahsburger, Emily K. Silzel, Rie Nakajima, Aarti Jain, Jacob Laster, Jui-Lin Chiang, Ya-Li Tsai, Philip Louis Felgner et al. · 2025 · npj Vaccines
- Prodrug‐Doped ROS‐Responsive Lipid Nanoparticle for Enhanced mRNA Delivery and Synergistic Anti‐Tumor TherapyZhuoying Liang, Kuikun Yang, Mao Li · 2025 · Small
- Advancing RNA delivery with Ionizable lipid nanoparticles: the roles of microfluidics and machine learningNeda Rostami, Mehdi Alidadi, Haniye Barzegar, Farzaneh Namazifar, Hadi Noei, Soudabeh Hosseini, Vladimir Nikolaevich Uversky, Taha Ghantabpour · 2025 · Nanomedicine
- Large and low-PEG lipid nanoparticles enable efficient dendritic cell targeting for potent mRNA Cancer vaccinesXiaolan Xu, Jiahao An, Dan Bai, Yuanchao Xu, Tingting Wu, Hua Yang, Yueyue Yan, Shaojun Yang, Zifan Wei, Yuchen Yao et al. · 2026 · Journal of Controlled Release
- Safety and efficacy of mRNA vaccines: a mechanistic and public health perspectiveAnna K. Blakney, Karina A. Top, Benjamin John Cowling, Heidi Jane Larson, Robin J. Shattock, Manish Sadarangani · 2026 · The Lancet
- Fluorescent Techniques for RNA Detection in NanoparticlesSimone Pinto Carneiro, Joschka T. Müller, Olivia M. Merkel · 2024 · Methods in molecular biology
- Immunostimulatory Response of RWFV Peptide-Targeted Lipid Nanoparticles on Bladder Tumor Associated CellsShayak Samaddar, Joshua Mazur, Jessica Sargent, David H. Thompson · 2021 · ACS Applied Bio Materials
- Lipid nanoparticles employed in mRNA-based COVID-19 vaccines: An overview of materials and processes used for development and productionIvana Pantelić, Jela Milić, Ines Nikolić, Snezana D. Savic · 2022 · Arhiv za farmaciju
- Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancerFilip Gorachinov, Fatima Mraiche, Diala Alhaj Moustafa, Ola Hishari, Yomna Ismail, Jensa Mariam Joseph, Maja Simonoska Crcarevska, Marija Glavaš Dodov, Nikola Geškovski, Katerina Goračinova · 2023 · Beilstein Journal of Nanotechnology
- Tetra-branched ionizable lipids enhance the stability and transfection efficiency of lipid nanoparticles for mRNA deliveryHaoran Xu, Jiaqi Fan, Jiwei Liu, Wei Dong Qi, Ruoshui Li, Pengcheng Yuan, Bing Xiao, Ying Piao, Wenjing Sun, Jiajia Xiang et al. · 2025 · Chinese Chemical Letters
- Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 VaccinesJános Szebeni, Ákos Koller · 2025 · Vaccines
- Dendronized Polymeric Biomaterial for Loading, Stabilization, and Targeted Cytosolic Delivery of microRNA in Cancer CellsVishakha Tambe, Sagarkumar Patel, Amit Shard, Santosh Kumar Behera, Suryanarayana Polaka, Neelima Anup, Anuradha Gadeval, Kiran Kalia, Rakesh Kumar Tekade · 2022 · ACS Applied Bio Materials
- Using nanomaterials to address SARS-CoV-2 variants through development of vaccines and therapeuticsMaria V. Hangad, Sarah Keshvani, Niya Kelpin, Jonathan Walters-Shumka, McKayla Hood, C. Volk, D. Pal, S. Willerth · 2022 · Frontiers in Materials
- Innovative translational platforms for rapid developing clinical vaccines against COVID‐19 and other infectious diseaseNing Wang, Ting Wang · 2024 · Biotechnology Journal
- RNA Order Regulates Its Interactions with Zwitterionic Lipid BilayersAkhil Pratap Singh, Janak Prabhu, Stefano Vanni · 2024 · Nano Letters
- Stealth oxime ether lipid vesicles promote delivery of functional DsiRNA in human lung cancer A549 tumor bearing mouse xenograftsAnu Puri, Faisal Ibrahim, André O’Reilly Beringhs, Camryn Isemann, Paul Zakrevsky, Abigail Whittenburg, Derek Hargrove, Tapan Kanai, Rebecca S. Dillard, Natalia de Val et al. · 2022 · Nanomedicine Nanotechnology Biology and Medicine
- Nano–Bio Interactions: Exploring the Biological Behavior and the Fate of Lipid-Based Gene Delivery SystemsSeigo Kimura, Hideyoshi Harashima · 2024 · BioDrugs
- Liposomes as Targeted Drug‐Delivery SystemsRaghavendra C. Mundargi, Neetika Taneja, Jayeshkumar J. Hadia, Ajay Jaysingh Khopade · 2022 · Methods and principles in medicinal chemistry
- Dual Ethanolamine Head Groups in Ionizable Lipids Facilitate Phospholipid-free Stable Nanoparticle Formulation for Augmented and Safer mRNA DeliveryJing Lu, Ting Shun Jiang, Xuechun Li, Shudan Tan, Yunsen Zhang, Hao Shuang Gu, Lin Chen, Junxiang Guo, Rui Yu, Jieying Zang et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Spatial Organization of Lipid Nanoparticle siRNA Delivery Systems Revealed by an Integrated Magnetic Resonance ApproachGal Porat‐Dahlerbruch, Ivan V. Sergeyev, Caitlin M. Quinn, Jochem O. Struppe, Daniel P. Banks, Charles Dahlheim, Donald Johnson, Denette K. Murphy, Andrew J. Ilott, Anuji Abraham et al. · 2024 · Small Methods
- Tumor Microenvironment-Responsive Lipid Nanoparticle for Blocking Mitosis and Reducing Drug Resistance in NSCLCFengrui Yang, Xiao-Rou Jiang, Lingling Lei, Jinghao Fu, Zeng‐Ping Chen, Ru-Qin Yu · 2025 · Journal of Medicinal Chemistry
- A Machine Learning Assisted Tool and Numerical Model for Analyzing Lipid NanoparticlesOwen Yuk Long Ip, Harrison D. E. Fan, Yao Zhang, Jerry Leung, Colton Strong, Janell Ko, Pieter R. Cullis, Miffy H. Y. Cheng · 2025 · ACS Nano
- High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical UltracentrifugationScott M. Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin Geilich, Gilles Besin, Borries Demeler · 2025 · Advanced Functional Materials
- An inhalable liquid-core lipid nanoplatform enables macrophage-mediated mRNA delivery to lung tumorsChang Liu, Ziwei Zhang, Ye Yuan, Hezhi Wang, Jian Guan, Shirui Mao · 2026 · Journal of Controlled Release
- Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical ProspectsYu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang · 2026 · Cancer Nexus
- Enhancing the delivery and stability of lipid nanoparticle–dsRNA formulations in the RNAi-recalcitrant fall armyworm (Spodoptera frugiperda)Marcel Kaarow, Leonie Graser, Eileen Knorr, Anton G. Windfelder, Pascal Geisler, Frank Steiniger, Markus Oberpaul, Andreas Vilcinskas, Christoph Hellmann · 2026 · Frontiers in Insect Science
- The Efficacy and Safety of Polyethylene Glycol Cholesterol- and Tocopherol Polyethylene Glycol 1000 Succinate-Modified Transforming Growth Factor β1 Small Interfering RNA Lipid Nanoparticles in the Treatment of Paclitaxel-Resistant Non-Small-Cell Lung CancerZhaowu Zeng, Xianglong Zeng, Xinyi Li, Yuxin Feng, Yue Kan, Xingyan Liu, Yiying Zeng · 2024 · Pharmaceutics
- Mechanistic insights into interactions between ionizable lipid nanodroplets and biomembranesPetra Čechová, Markéta Paloncýová, Martin Šrejber, Michal Otyepka · 2024 · Journal of Biomolecular Structure and Dynamics
- Unlocking the potential of nanocarrier-mediated mRNA delivery across diverse biomedical frontiers: A comprehensive reviewSmita Pawar, Prashant Pingale, Atul Garkal, Riyaz Ali M. Osmani, Kavita Rai Gajbhiye, Madhur Kulkarni, Krutika Pardeshi, Tejal A Mehta, Amarjitsing Rajput · 2024 · International Journal of Biological Macromolecules
- RP-CAD for Lipid Quantification: Systematic Method Development and Intensified LNP Process CharacterizationNicole Beckert, Annabelle Dietrich, Jürgen J. Hubbuch · 2024 · Pharmaceuticals
- Janus dendritic ionizable lipids with fine designed headgroup and tails to improve mRNA delivery efficiencyChao Liu, Yuhao Jiang, Wenliang Xue, Jinyu Liu, Zihao Wang, Xinsong Li · 2025 · Bioorganic & Medicinal Chemistry
- Facile lipid nanoparticle size engineering approach via controllable fusion induced by depletion forcesHeyun Wang, Hugo Pestre, Emie-Kim Ngo Tan, Linda Wedemann, Jan S. Schuhmacher, Milena Schuhmacher, Francesco Stellacci · 2025 · Journal of Colloid and Interface Science
- Premixing enables loading of long RNA in cubic phase lipid nanoparticlesHarin Jin, Iji Seo, Jongeon Park, Yunhee Seo, Jae Chul Park, Seunghwan Bang, Joonwoo Rhee, Kwan Hyi Lee, Jahyun Koo, Youngdo Jeong et al. · 2025 · Nature Communications
- Non‐Viral RNA Delivery During Pregnancy: Opportunities and ChallengesNamit Chaudhary, Alexandra N. Newby, Kathryn A. Whitehead · 2023 · Small
- Simple Scattering: Lipid nanoparticle structural data repositoryLee Joon Kim, David S. Shin, Wellington Claiton Leite, Hugh O’Neill, Oliver Ruebel, Andrew Tritt, Greg L. Hura · 2024 · Frontiers in Molecular Biosciences
- Capturing Structural Transitions in Surfactant Adsorption Isotherms at Solid/Solution InterfacesJunwoong Yoon, Zachary W. Ulissi · 2019 · Langmuir
- Water Content in Nanoparticles Determined by Small-Angle Neutron Scattering and Light ScatteringBehrad Kangarlou, Donyeil Hoy, Haden L. Scott, Sai Venkatesh Pingali, Nora Khalil, Benjamin Chung, John Katsaras, Mu‐Ping Nieh · 2022 · Langmuir
- Recent Advances in mRNA Vaccine DevelopmentAbebe Mengesha Aga, Musin Kelel, Mesfin Tafesse Gemeda · 2023 · Preprints.org
- The rise of mRNA therapeutic vaccinesJinlu Du, Ziling Fan, Jiangming Huang, Zhengyuan Li, Haitao Hu, Yanxia Li · 2025 · RSC Pharmaceutics
- Microfluidic Flow-Focusing for Size-Controlled Formation of CubosomesCelso J. O. Ferreira, Margarida Barros, Marco Fornasier, Alexandre Chícharo, Cláudia Botelho, Maria Elisabete C.D. Real Oliveira, Ulf Olsson, Bruno F. B. Silva · 2025 · Langmuir
- Optimizing the targeting of lipid nanoparticles for gene therapyLei Yue, Xiulei Gao, Wei Qi, Luhong Zhang, Yuefei Wang · 2025 · Nanoscale Horizons
- Guiding design and performance of nonviral nucleic acid delivery vehicles via machine learningJohn A. Hutchinson, Sidharth Panda, Plinio D. Rosales, Janey P Sowada, Miles S. Willis, Michael C. Leyden, Pródromos Daoutidis, Theresa M. Reineke · 2025 · Advanced Drug Delivery Reviews
- Long-acting lipid-based nanomedicines: rethinking from structure-based rational design to in vivo fate evaluationYixuan Tang, Shan Lu, Wanjun Liang, Yujing He, Jifu Hao, Wei Xu, Yuansong Sun, Changyou Zhan · 2025 · Journal of Controlled Release
- Alternative Structural Lipids Impact mRNA-Lipid Nanoparticle Morphology, Stability, and ActivityChelsea R. Thorn, James Collin Hickey, Ying‐Chih Chi, Mingzhang Maple Wang, Karina Ng Huang, Sue‐Jean Hong, Qin Zou, Hong-My Nguyen, Roger H. Pak, Patrick Lim Soo · 2025 · Molecular Pharmaceutics
- From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and FunctionErica Quagliarini, Daniela Pozzi, Giulio Caracciolo · 2026 · Advanced Healthcare Materials
- Challenges with the discovery of RNA-based therapeutics for flavivirusesMei-Yue Wang, Rong Zhao, Yu-Lan Wang, Deping Wang, Ji‐Min Cao · 2023 · Expert Opinion on Drug Discovery
- The Role of Formulation Approaches in Presenting Targeting Ligands on Lipid NanoparticlesRobert A. Castro, Elizabeth A. Aisenbrey, Liwei Hui · 2023 · Nanomedicine
- Targeting pediatric solid tumors in the new era of RNA therapeuticsParunya Chaiyawat, Surasak Sangkhathat, Wararat Chiangjong, Patompon Wongtrakoongate, Suradej Hongeng, Dumnoensun Pruksakorn, Somchai Chutipongtanate · 2024 · Critical Reviews in Oncology/Hematology
- Polymer Nano‐Carrier‐Mediated Gene Delivery: Visualizing and Quantifying DNA Encapsulation Using dSTORMXhorxhina Shaulli, Aura Maria Moreno‐Echeverri, Mariza Andoni, Eileen Lucia Waeber, Shivaprakash N. Ramakrishna, Cornelia Fritsch, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Frank Scheffold · 2024 · Small
- Molecular Dynamics Simulation on the Conformational Change of a pH-Switchable LipidHao Zhang, Xiaoyan Zhuang, Yutong Wang, Zhen Zhao, Lijuan Yan, Guangyong Li, Jun Li, Hui Yan · 2024 · Langmuir
- Microfluidic Optimization of PEI-Lipid Hybrid Nanoparticles for Efficient DNA Delivery and Transgene ExpressionMahboubeh Hosseini-Kharat, Anthony D. Wignall, Zelalem Addis Mekonnen, Benjamin S.‐Y. Ung, Bradley Chereda, Kristen E. Bremmell, Branka Grubor‐Bauk, Clive A. Prestidge · 2025 · Pharmaceutics
- Evaluation of liver specific ionizable lipid nanocarrier in the delivery of siRNAShilpa Rana, Archana Bhatnagar, Suman B. Singh, Nirmal Prabhakar · 2022 · Chemistry and Physics of Lipids
- New insights into the structure of Comirnaty Covid-19 vaccine: A theory on soft nanoparticles with mRNA-lipid supercoils stabilized by hydrogen bondsJános Szebeni, Bálint Kiss, Tamás Bozó, Keren Turjeman, Yael Levi‐Kalisman, Yechezkel Barenholz, Miklós Kellermayer · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Structural heterogeneity in mRNA-LNP subpopulations revealed by AF4-SAXS: implications for cargo loading and cell transfectionAdrian Sanchez-Fernandez, Keira A. Donnelly, Hans Bolinsson, Anna-Maria Börjesdotter, Thomas Rønnemoes Bobak, Simon Erlendsson, Meysam Mohammadi Zerankeshi, Khaled AboulFotouh, Mohammed R. Kawelah, Fátima Herranz-Trillo et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Evaluating the breadth of nucleic acid-based payloads delivered in lipid nanoparticles to establish fundamental differences in developmentJinjin Li, Camilla Foged · 2024 · Expert Opinion on Drug Delivery
- Structure–Function Correlation of Clinically Inspired Lipid Nanoparticles for Lung and Spleen Targeted mRNA DeliveryNatalia P. Martínez, Haitao Yu, Joshua Iscaro, Hao Wang, Brendan Dyett, Jacinta White, Celesta Fong, Calum John Drummond, Steven Bozinovski, Jiali Zhai · 2025 · Advanced Healthcare Materials
- Probing Membrane Structure of Lipid Nanomedicines Using Solution Small-Angle X-Ray Scattering: Applications and ProspectsKe-Meng Li, Panqi Song, Xiao‐Peng He, Na Li · 2025 · Membranes
- Drug-loaded nanoparticles reduced platelet aggregation and blood coagulationSarah Majin, Afrida Malik, Pratima Poudel, E. Vincent S. Faustino, Nubia Zuverza‐Mena, John Hwa, Seyedtaghi S. Takyar, Susan M. Shea, Kagya A. Amoako · 2026 · Frontiers in Medical Technology
- Azobenzene-bridged ionizable amphiphilic Janus glycosides for light-controlled, single-component and organ-modulable pDNA deliveryZhaoxin Wang, Gonzalo Rivero-Barbarroja, Juan Manuel Benito, Stéphane Maisonneuve, Itziar Vélaz, Inmaculada Juárez-Gonzálvez, Marı́a J. Garrido, Conchita Tros de Ilarduya, Carmen Ortiz Mellet, Juan Xie et al. · 2026 · Communications Chemistry
- Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational MethodsRuichu Gu, Duanmiao Si, Dingwei Lei, Xiaoxue Xie, Yongge Li, Han Wen · 2026 · MedComm
- Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid LeukemiaXiaofei Xin, Yifu Lyu, Huanyu Qin, Jinyu Dai, Di Wu, Yu Ding, Qiang Tian, Chao Qin, Na Li, Lifang Yin · 2026 · Journal of the American Chemical Society
- A functional lyoprotectant platform enables storage-stable, mucus-penetrating siRNA delivery to the lungWenliang Sun, Liangkun Xie, Xiaotong Jiang, Qingyi Zhu, Hu Fang Ji Feng, Dongmei Cun, Lan Wu, Mingshi Yang · 2026 · Journal of Controlled Release
- Silk‐Based Protein Corona Enhances mRNA‐LNP Vaccine Efficacy and Prevents Tumor RelapseShangyuan Cui, Zhongfeng Ye, Mariah Lynn Arral, Lihan Liu, Benson Weng, Xiaohan Zhang, Remya Nair, Yuchen Zhao, Jugal Kishore Sahoo, Shuliang Gao et al. · 2026 · Advanced Materials
- Fine‐Tuning Photochemical Immunogenic Cell Death by a Panel of Verteporfin‐Lipid Nanoparticles: A Data‐Driven ApproachNimit Shah, Maxwell Bortei Quaye, Siddharth Reddy Soma, Meghana Sree Vadlamudi, Doha Mahmoud, Ashritha Malkoochi, Taksheel Rao Aileni, Chanda Bhandari, Kunal Karambelkar, Tayyaba G. Hasan et al. · 2025 · Small Science
- Recent advances and clinical prospects of non-viral brain-targeted gene delivery systemsShuyu Wang, Lin-Lin Xu, Feihe Ma, Mengchen Xu, Guidong Chen, Da‐Yuan Wang, Xiaohui Wu, Peng Wang, Jinpu Yu, Linqi Shi · 2025 · Applied Physics Reviews
- Characterization of Peptide–Oligonucleotide Complexes Using Electron Microscopy, Dynamic Light Scattering, and Protease Resistance AssayKärt Padari, Ly Porosk, Piret Arukuusk, Margus Pooga · 2019 · Methods in molecular biology
- Engineering Lipid Spherulites for the Sustained Release of Highly Dosed Small Hydrophilic CompoundsElita Montanari, Hanna Krupke, Jean‐Christophe Leroux · 2022 · Advanced Healthcare Materials
- Increasing the siRNA knockdown efficiency of lipid nanoparticles by morphological transformation with the use of dihydrosphingomyelin as a helper lipidMasahiro Hashimoto, Sei Yonezawa, Furan Song, Chiori Nitta, Noriyuki Maeda, Koji Tomita, Ayano Yokouchi, Hiroyuki Koide, Tomohiro Asai · 2023 · Biomaterials Science
- Physiological Determinants and Plausible ‘6R’ Roadmap for Clinical Success of NanomedicinesAliasgar Shahiwala · 2023 · Nanomedicine
- In Silico Engineering of Stable siRNA Lipid Nanoparticles: Exploring the Impact of Ionizable Lipid Concentrations for Enhanced Formulation StabilityMalay Ranjan Biswal, Sudip Roy, Jayant Kumar Singh · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- RNAi in Cancer TherapySubhrojyoti Ghosh, Diganta Chaudhury, Ankita Chowdhury, Nandan Kumar Jana · 2025 · Interdisciplinary biotechnological advances
- Designing and modeling nanomedicines towards image-guided drug delivery in hematological malignanciesShiva Khorshid, Julian Baumeister, Federica De Lorenzi, Mattia Tiboni, Sara Elsafy, Alessandro Motta, Alessia Nucci, Saskia Freifrau von Stillfried, Nicolas Chatain, Fabian M. Kiessling et al. · 2025 · Journal of Controlled Release
- Precision engineering of macrophage reprogramming with RNA interference-loaded lipid nanoparticles: a game-changer in cancer immunotherapySezen Gül, Juliette Vergnaud, François Fay, Elias Fattal · 2025 · Drug Delivery and Translational Research
- Anion-exchange high-performance liquid chromatography: A new approach to monitoring the formation of mRNA-loaded lipid nanoparticles during manufacturingShoki Hara, Takuya Suzuki, Iori Mizogaki, Takayuki Miyazaki, Keita Kondo, Shuntaro Arase, Yuta Suzuki, Shinya Sato, Koji Ukai · 2025 · Journal of Pharmaceutical Sciences
- Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in SolutionRui Chen, Letao Xu, Nan Zhang, Haitao Yu, Xing Wang, Jiali Zhai, Fiona Whelan, Phillip Elliott, Chun‐Xia Zhao · 2025 · Advanced Science
- NMR-Based Molecular-Level Characterization: A Review of Its Application in Unveiling Lipid Nanoparticle FormulationsK. Ueda · 2025 · Chemical and Pharmaceutical Bulletin
- Toroidal mixers for microfluidic assembly of therapeutic lipid nanoparticles (LNPs): a reviewJiwoo Choi, Haegyo Jeong, Seon Yeop Jung, Seyoung Kim · 2025 · Korea-Australia Rheology Journal
- Mapping Hydration and Nanoarchitecture in mRNA‐Loaded Lipid Nanoparticles Through Small‐Angle Neutron ScatteringHaikun Liu, Mark Louis P. Vidallon, Sylvain Trépout, Marina Cagnes, Nageshwar Rao Yepuri, Tamim A. Darwish, Mitchell J. Moon, Pu Shi, Aidan P. G. Walsh, Rico F. Tabor et al. · 2025 · Small Structures
- Coarse-Grained Molecular Dynamics Simulations of Lipid Nanodroplets and Endosomal Membranes: Focusing on the Fusion MechanismsYeon Ju Go, Erkhembayar Jadamba, Hyunjin Shin · 2025 · International Journal of Molecular Sciences
- Impact of ionizable lipid source on quality and stability of siRNA-loaded lipid nanoparticlesSheyda Ranjbar, Kuo‐Chih Shih, André O’Reilly Beringhs, Bin Qin, Yan Wang, Deyi Zhang, William Smith, Afshin Seyednejad, Luke Burroughs, Diane J. Burgess et al. · 2026 · Journal of Controlled Release
- Microfluidic process-property correlations of dsRNA lipid nanoparticle formulationsPascal Geisler, Eileen Knorr, Frank Steiniger, Artem Levin, Christoph Hartwig, Till F. Schäberle, Andreas Vilcinskas, Christoph Hellmann · 2026 · Scientific Reports
- Monitoring pH-induced lipid dynamics in mRNA-lipid nanoparticles by synchrotron small-angle X-ray scatteringKe‐meng Li, Panqi Song, Zi-Ru Ye, Hao Li, Qiang Tian, Jialin Duan, Xiao‐Peng He, Na Li · 2026 · Journal of Controlled Release
- Biomimetic lipid nanoparticles for macrophage reprogramming in cancer immunotherapy고승효, Ga‐Hyun Bae, Eun-Young Koh, Seungyong Shin, J W. Park, Ha Eun Shin, Wooram Park · 2026 · Journal of Controlled Release
- From Morphology to Mechanism: Cryo-Electron Microscopy Insights into Lipid Nanoparticles for RNA DeliveryYulin Mo, Gang Zheng · 2026 · ACS Nano
- Generation of continuous production of polymeric nanoparticles via microfluidics for aerosolised localised drug deliveryGiuseppina Catania, Giulia Guerriero, Naoual Bakrin, Jérémie Pourchez, Ghalia Kaouane, Lara Leclerc, Lionel Augeul, Ragna Haegebaert, Katrien Remaut, David Kryza et al. · 2025 · International Journal of Pharmaceutics
- Formation of RNA lipid nanoparticles: an equilibrium process with a liquid intermediate stageJessica Boutros, Ziyue Li, Leah Wright, Robert John Falconer · 2025 · Soft Matter
- Harnessing dendritic cells as immunological bridges to potentiate mRNA cancer vaccinesRuiying Wu, Huixin Li, Ziqin Li, Kai Hao, Huayu Tian · 2025 · Journal of Materials Chemistry B
- Effects of the structure of lipid-based agents in their complexation with a single stranded mRNA fragment: a computational studyAnastassia N. Rissanou, Kostas Karatasos · 2022 · Soft Matter
- Progress on mRNA vaccines and lipid nanoparticlesYuchuan Fan, Han Yin, Yu Li, Yu Xi, Xiaoying Tang, Yuhua Weng, Yuanyu Huang · 2024 · Chinese Science Bulletin (Chinese Version)
- Characterization of lipid nanoparticles using macro mass photometry: Insights into size and massJikang Wu, Yu Zhang, Zhijie Wu, Julia Alma Townsend, Ivor Crooks, Brenda Watt, Andrew D. Baik, Katherine D. Cygnar, Haibo Qiu, Ning Li · 2025 · Analytica Chimica Acta
- Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and VectorsJoshua A. Choe, Jacobus C. Burger, Jamie Jones, Apurva Panjla, William L. Murphy · 2025 · Advanced Therapeutics
- Therapeutic Lipid Nanoparticles Delivery of Small Interfering RNA for the Synergistic Treatment of Hepatic InflammationNan Wang, Jiaxin Li, Wen Ji Zhang, Xinyue Zhang, Peng Chen, Keyi Zhang, Yong Hua Ji, Zhirui Li, Guanghui Ouyang, Yan Li · 2025 · Advanced Healthcare Materials
- Therapeutic potential and clinical translation of nanodrugs: A path forward- case studies from bench to bedsideFatima Khalifa Al‐Sulaiti, Selma Şahin · 2025 · Journal of Drug Delivery Science and Technology
- Photolipid Isomerization in Multicomponent Lipid Membranes: Effects of Temperature and ChargeDominik Kammerer, Dirk H. Trauner, Theobald Lohmüller · 2025 · Langmuir