On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
Kulkarni, Jayesh A., Darjuan, Maria M., Mercer, Joanne E., Chen, Sam, van der Meel, Roy, Thewalt, Jenifer L., Tam, Yuen Yi C., Cullis, Pieter R.·2018·ACS Nano
Cited by (662)
Items 301–400 of 662
- Structural insights on ionizable Dlin-MC3-DMA lipids in DOPC layers by combining accurate atomistic force fields, molecular dynamics simulations and neutron reflectivityMohd Ali Ibrahim, Jennifer Gilbert, Marcel Heinz, Tommy Nylander, Nadine Schwierz · 2023 · Nanoscale
- Investigation of enhanced intracellular delivery of nanomaterials modified with novel cell-penetrating zwitterionic peptide-lipid derivativesSugimoto, Yuri, Suga, Tadaharu, Umino, Mizuki, Yamayoshi, Asako, Mukai, Hidefumi, Kawakami, Shigeru · 2023 · Drug Delivery
- Development of Spray-Dried Micelles, Liposomes, and Solid Lipid Nanoparticles for Enhanced StabilityShradha Dattani, Xiaoling Li, Charina Lampa, Amanda Barriscale, Behzad Damadzadeh, David Lechuga‐Ballesteros, Bhaskara Jasti · 2025 · Pharmaceutics
- Not so cold! Improving the thermostability of mRNA vaccinesJean Haensler, Luc Even, Pierre Wils, Fethi Bensaid, Anusha Dias, Hongfeng Deng, Shrirang Karve, Frank DeRosa · 2025 · Expert Review of Vaccines
- Ultrasound-assisted biomimetic nanobubbles for targeted treatment of atherosclerosisXin Hu, Pengxuan Zhao, Jun Zhang, Ying Zhu, Wei Zhou, Kai Hong, Ruiying Sun, Yuxue Wang, Yongping Lu, Yani Liu · 2023 · Nanomedicine Nanotechnology Biology and Medicine
- Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia AAmy W. Strilchuk, Woosuk S. Hur, Paul A Batty, Yaqiu Sang, Sara R. Abrahams, Alyssa S. M. Yong, Jerry Leung, Lakmali Munasinghage Silva, Jocelyn A. Schroeder, Kate Nesbitt et al. · 2024 · Science Translational Medicine
- Nanotechnology for organ-tunable gene editingRoy van der Meel · 2020 · Nature Nanotechnology
- Development of an advanced separation and characterization platform for mRNA and lipid nanoparticles using multi-detector asymmetrical flow field-flow fractionationZiting Gao, Jessica Lin, Wan-Chih Su, Kelly Zhang, Jason Gruenhagen, Wenwan Zhong, Yuchen Fan, Juan Bian · 2024 · Analytical and Bioanalytical Chemistry
- Targeting Neuroinflammation in Central Nervous System Diseases by Oral Delivery of Lipid NanoparticlesYuan Zou, Jing Zhang, Longmin Chen, Qianqian Xu, Sheng Yao, Hong Chen · 2025 · Pharmaceutics
- Influence of salt solution on the physicochemical properties and in vitro/ in vivo expression of mRNA/LNPSiyuan Tang, Lei Huang, Jiahao Ge, Jie Li, Mingxia Qiu, Yiqing Zhang, Mei Long, Gang Wu, Rui Zhang, Xueyun Ma et al. · 2025 · Journal of Nanobiotechnology
- Co-Formulation of Amphiphilic Cationic and Anionic Cyclodextrins Forming Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid LeukaemiaAyse Kont, Monique Culturato Padilha Mendonça, Michael F. Cronin, Mary R. Cahill, Caitríona M. O’Driscoll · 2022 · International Journal of Molecular Sciences
- On the Influence of Nucleic Acid Backbone Modifications on Lipid Nanoparticle MorphologyKevin An, Daniel Z. Kurek, Mark Mahadeo, Yao Zhang, Jenifer L. Thewalt, Pieter R. Cullis, Jayesh A. Kulkarni · 2022 · Langmuir
- A nanoplatform self‐assembled by coordination delivers siRNA for lung cancer therapyZiyao Wang, Jie Mei, Dongqi Ni, Shengmei Li, Jin-Min Ye, Shilin Li, Yaling Wang, Ying Liu · 2023 · Rare Metals
- Ionic liquid-coated lipid nanoparticles increase siRNA uptake into CNS targetsPurva Khare, Sara X. Edgecomb, Christine M. Hamadani, James F. Conway, Eden E. L. Tanner, Devika Soundara Manickam · 2023 · Nanoscale Advances
- Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural ParametrizationElizabeth R. Webster, Nicole E. Peck, Juan Diego Echeverri, Shima Gholizadeh, Wei-Lun Tang, Rinette W.L. Woo, Anushtha Sharma, Weiqun Liu, Chris S. Rae, Adrienne Sallets et al. · 2024 · ACS Nano
- Production, Characterization, and Assessment of Permanently Cationic and Ionizable Lipid Nanoparticles for Use in the Delivery of Self-Amplifying RNA VaccinesKairuz, Dylan, Samudh, Nazia, Ely, Abdullah, Arbuthnot, Patrick, Bloom, Kristie · 2023 · Pharmaceutics
- High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development PipelineLois Lam, Stephanie Louise Watson, Yogambha Ramaswamy, Gurvinder Singh · 2025 · Advanced Science
- Hybrid hydrogels for biomedical applications: Addressing challenges in drug delivery through advanced crosslinking and nanocarrier integrationMuhammad Zahid Anwar, Himanshu Kathuria, Jen Xi Er, Yishu Wang, Gigi N.C. Chiu · 2026 · Journal of Controlled Release
- Characterization and associated pressure-dependent behavior of deposits formed during sterile filtration of mRNA-Lipid nanoparticlesKevork Oliver Messerian, Anton Zverev, Jack F. Kramarczyk, Andrew L. Zydney · 2023 · Journal of Membrane Science
- Determination of the interior pH of lipid nanoparticles using a pH-sensitive fluorescent dye-based DNA probeBin Zhao, Albert Kamanzi, Yao Zhang, Karen Y. T. Chan, Madelaine K. Robertson, Sabrina R. Leslie, Pieter R. Cullis · 2024 · Biosensors and Bioelectronics
- Probing Molecular Packing of Lipid Nanoparticles from 31P Solution and Solid-State NMRRyan V. Schroder, Phillip James Dorsey, Joe Vanderburgh, Wei Xu, Suzanne M. D’Addio, Lee J. Klein, Marian E. Gindy, Yongchao Su · 2024 · Analytical Chemistry
- Ionizable Drugs Enable Intracellular Delivery of Co‐Formulated siRNAKai V. Slaughter, Eric N. Donders, Michael S. Jones, Sami G. Sabbah, Mitchell J. Elliott, Brian K. Shoichet, David W. Cescon, Molly Sandra Shoichet · 2024 · Advanced Materials
- NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicinesMariona Estapé Sentí, Alexandre Ceccaldi, Marta Luciani, Nadine Saber, Paul J. L. Schürmann, Maurits W. Geerlings, Peter Hölig, Joel de Beer, Michael Hannus, Fred Campbell et al. · 2025 · Frontiers in Science
- Scalable Production of Lipid Nanoparticles Containing Amphotericin BJayesh A. Kulkarni, Sam Chen, Yuen Yi C. Tam · 2021 · Langmuir
- Time-dependent particle size increase during lipid nanoparticle purification by cross-flow filtrationAnnabelle Dietrich, Nicole Beckert, Jürgen J. Hubbuch · 2025 · Journal of Colloid and Interface Science
- Buffer optimization of siRNA-lipid nanoparticles mitigates lipid oxidation and RNA-lipid adduct formationDaniel A. Estabrook, Lihua Huang, Olivia R. Lucchese, Dylan J. Charland, Yu Rong Zhao, Fareed Bhasha Sayyed, Jonas Y. Buser, Younghoon Oh, Xingyan Liu, Harmon A. Johnson et al. · 2025 · Nature Communications
- Drug Targeting and Nanomedicine: Lessons Learned from Liver Targeting and Opportunities for Drug InnovationAnna Laura Salvati, Klaas Poelstra · 2022 · Pharmaceutics
- Lipoplexes and polyplexes as nucleic acids delivery nanosystems: The current state and future considerationsBruno Costa, Beatriz Boueri, Claudia L. Oliveira, Isabel Silveira, António José Ribeiro · 2022 · Expert Opinion on Drug Delivery
- Self-assembled flagella protein nanofibers induce enhanced mucosal immunityDuo Fu, Mengjia Wang, Tao Yang, Min Li, Zhihui Liang, Chen Chen, Lei Zhang, Changying Xue, Bingbing Sun, Chuanbin Mao · 2022 · Biomaterials
- Natural long-chain saturated fatty acids doped LNPs enabling spleen selective mRNA translation and potent cancer immunotherapyFazhan Wang, Meng Zhang, Meiling Tian, Jia Lou, Longze Pan, Xiaoke Gao, Lijing Zhang, Xiaohan Lou, Linyu Zhu, Yuqiao Sheng et al. · 2023 · Nano Research
- Inhibition of the MALT1-LPCAT3 axis protects cartilage degeneration and osteoarthritisVijay Kumar Reddy Kondreddy, Rintu Banerjee, Bethala L. A. Prabhavathi Devi, Kathirvel Muralidharan, Piramanayagam Selvakumar · 2024 · Cell Communication and Signaling
- RNA interference therapeutics for cardiac regenerationJosef Huntington, Manendra Pachauri, Hashim Ali, Mauro Giacca · 2021 · Current Opinion in Genetics & Development
- Lipid nanoparticles: A delicate nucleic acid delivery system to be further exploredRunpu Ma, Yuting Li, Yang Su, Peng Chen, Sitao Xie, Weihong Tan, Xiangsheng Liu · 2024 · Nano Today
- Frit-inlet asymmetric flow field-flow fractionation for the analysis of lipid nanoparticle-protein interactionsRand Abdulrahman, Panida Punnabhum, Robin Bruno Capomaccio, Kevin Edward Treacher, Yvonne Perrie, Zahra Rattray · 2025 · Journal of Chromatography A
- Intracellular trafficking of lipid nanoparticles is hindered by cholesterolChengzhi Luo, Yunfei Li, Haidong Liu, Jing He, Xiaojuan Yang, E. Zhao, Guanghui Zi, L.-Z. Liu, Yujia Hong, Hui Wang et al. · 2025 · International Journal of Pharmaceutics
- RNA lipid nanoparticles stabilized during nebulization through excipient selectionKai V. Slaughter, Daniela Isaacs-Bernal, Eric N. Donders, Siming Wang, Sami G. Sabbah, Xiang (Olivia) Li, Mickael Dang, Isaac M. Jackiw, Karen Y. T. Chan, Pieter R. Cullis et al. · 2025 · Nanoscale Advances
- Design, strategies, and therapeutics in nanoparticle-based siRNA delivery systems for breast cancerChangjiao Yan, Juliang Zhang, Meiling Huang, Jingjing Xiao, Nanlin Li, Ting Wang, Rui Ling · 2023 · Journal of Materials Chemistry B
- Hybrid LNP Prime Dendritic Cells for Nucleotide DeliveryRiddha Das, Elias A. Halabi, Ina R. Fredrich, Juhyun Oh, Hannah M. Peterson, Xinying Ge, Ella Scott, Rainer H. Köhler, Christopher Garris, Ralph Weissleder · 2023 · Advanced Science
- Nanoparticles Based on Natural Lipids Reveal Extent of Impacts of Designed Physical Characteristics on Biological FunctionsNiko Kimura, Yôko Tanaka, Yoko Yamanishi, Akiko Takahashi, Shinya Sakuma · 2024 · ACS Nano
- Lipid nanoparticle mediated small interfering RNA delivery as a potential therapy for Alzheimer's diseaseTanvir Ahmed · 2024 · European Journal of Neuroscience
- β-Cyclodextrin-based geometrically frustrated amphiphiles as one-component, cell-specific and organ-specific nucleic acid delivery systemsGonzalo Rivero-Barbarroja, José Manuel García Fernández, Inmaculada Juárez-Gonzálvez, Carlos Fernández-Clavero, Christophe Di Giorgio, Itziar Vélaz, Marı́a J. Garrido, Juan Manuel Benito, Carmen Ortiz Mellet, Francisco Mendicuti et al. · 2024 · Carbohydrate Polymers
- Toward a Complete Elucidation of the Primary Structure–Activity in Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers for In Vivo Delivery of Luc-mRNADipankar Sahoo, Elena N. Atochina‐Vasserman, Juncheng Lu, Devendra S. Maurya, Nathan A. Ona, Jessica A. Vasserman, Houping Ni, Sydni Berkihiser, W. Park, Drew Weissman et al. · 2024 · Biomacromolecules
- Molecular Insight into Lipid Nanoparticle Assembly from NMR Spectroscopy and Molecular Dynamics SimulationMingyue Li, Ryan V. Schroder, Umut Ozuguzel, Tyler Matthew Corts, Yong Liu, Yuejie Zhao, Wei Xu, Jing Ling, Allen C. Templeton, Bodhisattwa Chaudhuri et al. · 2025 · Molecular Pharmaceutics
- Translating nanomedicines: Thinking beyond materials? A young investigator's reply to ‘The Novelty Bubble’Dominik Witzigmann, Sjoerd Hak, Roy van der Meel · 2018 · Journal of Controlled Release
- Aptamer-Drug Conjugates (ApDCs): Transformative approaches in targeted cancer therapy and precision oncologyAmir Mohammad Zahedi, Mohammad Pirouzbakht, Saeed Zanganeh, Ali Afgar · 2025 · International Journal of Pharmaceutics
- Biomaterial-Based Nucleic Acid Delivery Systems for In Situ Tissue Engineering and Regenerative MedicineQi-Xiang Wu, N. de Isla, Lei Zhang · 2025 · International Journal of Molecular Sciences
- Advances in Lipid-Based Nanomedicine: Pathway Specific siRNA Therapy and Optimizing Delivery for Hepatocellular CarcinomaKarkaz Mohammed Thalij, Huay Woon You, Kiran Balasaheb Aher, Girija Balasaheb Bhavar, Smita Tukaram Kumbhar, Mohammad Habeeb · 2025 · International Journal of Nanomedicine
- Endosomal escape and current obstacles in ionizable lipid nanoparticles mediated gene delivery: lessons from COVID-19 vaccinesSemmal Syed Meerasa, Aqeel Ahmad, Amer Ali Khan, Shafiul Haque, Imran Y. Saleem · 2025 · International Journal of Pharmaceutics
- Recent Advances in Messenger Ribonucleic Acid (mRNA) Vaccines and Their Delivery Systems: A ReviewWubetu Yihunie Belay, Getinet Nibret, Yibeltal Aschale · 2023 · Clinical Pharmacology Advances and Applications
- Exploration of mRNA nanoparticles based on DOTAP through optimization of the helper lipidsXueni Ma, Fanqi Wu, Caihong Peng, Huiling Chen, Dekui Zhang, Tiyun Han · 2023 · Biotechnology Journal
- Lipid nanoparticle formulations for targeting leukocytes with therapeutic RNA in liver fibrosisMatthias Bartneck · 2021 · Advanced Drug Delivery Reviews
- Single pot organic solvent-free thermocycling technology for siRNA-ionizable LNPs: a proof-of-concept approach for alternative to microfluidicsAnindita De, Young Tag Ko · 2022 · Drug Delivery
- Altering the intra-liver distribution of phospholipid-free small unilamellar vesicles using temperature-dependent size-tunabilityJulian Vogler, Roland Böttger, Nojoud AL Fayez, Wunan Zhang, Zhu Qin, Lukas Hohenwarter, Po‐Han Chao, Elham Rouhollahi, Nida Bilal, Naliangzi Chen et al. · 2021 · Journal of Controlled Release
- EVQuant; high-throughput quantification and characterization of extracellular vesicle (sub)populationsThomas A. Hartjes, Johan A. Slotman, M.S. Vredenbregt, N. F. J. Dits, Roy van der Meel, Diederick Duijvesz, Jayesh A. Kulkarni, Pim J. French, Wiggert A. van Cappellen, Raymond Michel Schiffelers et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Anionic lipids direct efficient microfluidic encapsulation of stable and functionally active proteins in lipid nanoparticlesSuresh Ambati, Yeqi Li, Matthew K. Whittaker, Eileen J. Kennedy, Wided Najahi‐Missaoui, Xiaorong Lin, Zachary Lewis, Richard B. Meagher · 2025 · Communications Materials
- Morphological changes induced by buffer exchange during preparation of mRNA-lipid nanoparticles occur in a stepwise manner as pH is elevatedYujia He, Emily H. Pilkington, Hee Jung Kang, Wye‐Khay Fong, Andrew J. Clulow, Angus P. R. Johnston, Colin William Pouton · 2025 · Molecular Therapy — Methods & Clinical Development
- Structuring of lipid nanoparticle mRNA formulations at acidic and neutral pH: X-ray scattering and molecular dynamics studiesAmali G. Guruge, Yujia He, Andrew J. Clulow, Colin William Pouton, David K. Chalmers · 2025 · Molecular Therapy — Methods & Clinical Development
- Phase‐Separated Lipid‐Based Nanoparticles: Selective Behavior at the Nano‐Bio InterfacePanagiota Papadopoulou, Rianne van der Pol, Niek van Hilten, Winant L. van Os, Roy Pattipeiluhu, Gabriela Arias‐Alpizar, Renzo A. Knol, Willem E. M. Noteborn, Mohammad‐Amin Moradi, Maria J. Ferraz et al. · 2023 · Advanced Materials
- Computational approaches to lipid-based nucleic acid delivery systemsGiovanni Settanni · 2023 · The European Physical Journal E
- Molecular Dynamics Simulation of Lipid Nanoparticles Encapsulating mRNAZhigang Zhang, Dazhi Cheng, Wenqin Luo, Donling Hu, Tiantian Yang, Kaixuan Hu, Li Liang, Wei Liu, Jianping Hu · 2024 · Molecules
- Inclusion of Cationic Amphiphilic Peptides in Fmoc-FF Generates Multicomponent Functional HydrogelsMariangela Rosa, Enrico Gallo, Paolo Pellegrino, Flavia Anna Mercurio, Marilisa Leone, Mariafrancesca Cascione, Barbara Carrese, Giancarlo Morelli, Antonella Accardo, Carlo Diaferia · 2024 · ACS Applied Bio Materials
- Microfluidic fabrication of lipid nanoparticles for co-delivery of siRNA and hydroxychloroquine: An engineered theranostic platform for enhanced breast cancer treatmentLu Jun Huang, Wenli Guo, Ting Zhao, Yanru Feng, Yue Li, Qingqing An, Chenxi Li, Yiwei Tian, Huaxing Zhang, Chenming Zhou et al. · 2025 · Chemical Engineering Journal
- Nucleic acid vaccines: innovations, efficacy, and applications in at-risk populationsEmily Konopka, Arden O. Edgerton, Michele A. Kutzler · 2025 · Frontiers in Immunology
- A Molecular View of Lipid Nanoparticles: Insights into their Morphology and Structural PlasticitySudha Porte, V Vadhana, Durba Sengupta · 2025 · Small
- Study and Evaluation of the Potential of Lipid Nanocarriers for Transdermal Delivery of siRNAKyungwoo Lee, Daejin Min, Yonghyun Choi, Jiwon Kim, Semi Yoon, Jaehee Jang, Soomin Park, Masayoshi Tanaka, Yong Woo Cho, Hyung‐Jun Koo et al. · 2020 · Biotechnology Journal
- Acid‐Responsive Polymer Additives Increase RNA Transfection from Lipid NanoparticlesTimothy H. Cheung, Alexander Fuchs, Molly Sandra Shoichet · 2024 · Advanced Functional Materials
- Structural characterization of mRNA lipid nanoparticles (LNPs) in the presence of mRNA-free LNPsXiaoxia Chen, Yongfeng Ye, Mengrong Li, Taisen Zuo, Zhenhua Xie, Yubin Ke, He Cheng, Liang Hong, Zhuo Liu · 2025 · Journal of Controlled Release
- Hydrodynamic focusing to synthesize lipid-based nanoparticles: Computational and experimental analysis of chip design and formulation parametersMahmoud Abdelkarim, Amr Abostait, Samuel Czitrom, Sarah McColman, Ilhaan Ahmed, Charles Chan Wai Wong, D. Bogojevic, Mohamed Omar Abdelgawad, Hagar I. Labouta · 2025 · Journal of Controlled Release
- Stability Criterion for the Assembly of Core–Shell Lipid–Polymer–Nucleic Acid NanoparticlesJuan Luis Paris, Ricardo Gaspar, Filipe Coelho, Pieter De Beule, Bruno F. B. Silva · 2023 · ACS Nano
- Instability of membranes containing ionizable cationic lipids: Effects of the repulsive range of headgroups and tail structuresHao-Chun Huang, Chih‐Jung Lin, Yu‐Jane Sheng, Heng‐Kwong Tsao · 2024 · Colloids and Surfaces B Biointerfaces
- VitroJet: new features and case studiesRené Henderikx, Daniel Mann, Aušra Domanska, Jing Dong, Saba Shahzad, Behnam Lak, Aikaterini Filopoulou, Damian L. Ludig, Martin Grininger, Jeffrey Momoh et al. · 2024 · Acta Crystallographica Section D Structural Biology
- NMR-based analysis of impact of siRNA mixing conditions on internal structure of siRNA-loaded LNPK. Ueda, Yui Sakagawa, Tomoki Saito, Fumie Sakuma, Hiroki Tanaka, Hidetaka Akita, Kenjirou Higashi, Kunikazu Moribe · 2024 · Journal of Controlled Release
- Therapeutic applications of cell engineering using mRNA technologyYujia He, Angus P. R. Johnston, Colin William Pouton · 2024 · Trends in biotechnology
- Molecular Dynamics of Lipid Nanoparticles Explored through Solution and Solid-State NMR Spectroscopy and MD SimulationsRyan V. Schroder, Umut Ozuguzel, Yong Du, Tyler Matthew Corts, Yong Liu, Sachin Mittal, Allen C. Templeton, Bodhisattwa Chaudhuri, Marian E. Gindy, Angela Wagner et al. · 2025 · The Journal of Physical Chemistry B
- The diffusion-driven microfluidic process to manufacture lipid-based nanotherapeutics with stealth properties for siRNA deliveryİsmail Eş, Antônio A. Malfatti-Gasperini, Lucimara Gaziola de la Torre · 2022 · Colloids and Surfaces B Biointerfaces
- Lipidic Formulations Inspired by COVID Vaccines as Smart Coatings to Enhance Nanoparticle-Based Cancer TherapyMarzia Conte, Marco Carofiglio, Giada Rosso, Valentina Cauda · 2023 · Nanomaterials
- Microfluidic Generation of Diverse Lipid Nanoparticle LibrariesAndrew R. Hanna, Sarah J. Shepherd, David Issadore, Michael J. Mitchell · 2024 · Nanomedicine
- Systematic screening of excipients to stabilize aerosolized lipid nanoparticles for enhanced mRNA deliveryBrittany J. Heiser, Mae M. Lewis, Meysam Mohammadi Zerankeshi, Emily K. Netemeyer, Ashlee M. Hernandez, Alexander E. Marras, Debadyuti Ghosh · 2025 · RSC Pharmaceutics
- Diverse structures and shapes of lipid-based nanoparticles: Toward clinical translationKarolina Kustrzyńska, Gabriela Soińska, Paulina Skupin-Mrugalska · 2026 · Biomedicine & Pharmacotherapy
- Vaccine Formulation Strategies and Challenges Involved in RNA Delivery for Modulating Biomarkers of Cardiovascular Diseases: A Race from Laboratory to MarketMd. Adil Shaharyar, Rudranil Bhowmik, Fahad Ahmed Al-Abbasi, Shareefa Abdullah AlGhamdi, Amira M. Alghamdi, Arnab Sarkar, Imran Ahmed Kazmi, Sanmoy Karmakar · 2023 · Vaccines
- Pharmaceutical strategies for optimized mRNA expressionYingying Shi, Jiapeng Mao, Sijie Wang, Siyao Ma, Lihua Luo, Jian You · 2024 · Biomaterials
- Lipid Nanoparticles for mRNA Delivery in Cancer ImmunotherapyYasir Alshehry, Xiang Liu, Wenhua Li, Qiyan Wang, Janét Cole, Guizhi Zhu · 2025 · The AAPS Journal
- Hydatidiform mole: a vascular congenital anomaly.S. R. M. Reynolds · 1976 · PubMed
- The mechanical properties of lipid nanoparticles depend on the type of biomacromolecule they are loaded withSixtine de Chateauneuf-Randon, Bruno Bresson, Manon Ripoll, Sylvain Huille, Étienne Barthel, Cécile Monteux · 2024 · Nanoscale
- Unlocking the potential of transdermal drug deliveryShuang Li, Jianhao Wu, Xiangjun Peng, Xi‐Qiao Feng · 2024 · International Journal of Smart and Nano Materials
- Lipid-based Non-viral Vector: Promising Approach for Gene DeliveryAnupama Panday, Bhupendra Dixena, Nishant Sudhir Jain, Akhlesh Kumar Jain · 2024 · Current Pharmaceutical Design
- Boosting mRNA‐Engineered Monocytes via Prodrug‐Like Microspheres for Bone Microenvironment Multi‐Phase RemodelingYuansheng Wu, Yingjie Zhu, Jie Chen, Lili Song, Chunping Wang, Yanglin Wu, Yanyang Chen, Jiancheng Zheng, Yuankun Zhai, Xiang Zhou et al. · 2024 · Advanced Healthcare Materials
- Applications of microfluidics in mRNA vaccine development: A reviewAli Fardoost, Koosha Karimi, Harshitha Govindaraju, Pegah Jamali, Mehdi Javanmard · 2024 · Biomicrofluidics
- pH-sensitive, tail-modified, ester-linked ionizable cationic lipids for gene deliveryYu Zou, Yuhong Zhen, Yinan Zhao, Huiying Chen, Rui Wang, Wei Wang, Pengfei Ma, Defu Zhi, Benzhi Ju, Shubiao Zhang · 2022 · Biomaterials Advances
- Lipidoid nanoparticles increase ATP uptake into hypoxic brain endothelial cellsPurva Khare, James F. Conway, Devika Soundara Manickam · 2022 · European Journal of Pharmaceutics and Biopharmaceutics
- Morphology evolution of lipid nanoparticle discovered by small angle neutron scatteringYuqing Li, Changli Ma, Zehua Han, Weifeng Weng, Si‐Cong Yang, Zepeng He, Zheqi Li, Xiaoye Su, Taisen Zuo, He Cheng · 2024 · Giant
- Short interfering RNA delivered by a hybrid nanoparticle targeting VEGF: Biodistribution and anti-tumor effectGabriela Regina Rosa Souza, Milene Dalmina, Jelver Alexander Sierra, Leônidas João de Mello, Adny Henrique Silva, Ana Cristina Moura Gualberto, Jacy Gameiro, Dalton Dittz, Andre Avelino Pasa, Frederico Pittella et al. · 2021 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Tools shaping drug discovery and developmentEugene Cheung, Yan Xia, Marc A. Caporini, Jamie L. Gilmore · 2022 · Biophysics Reviews
- RP-HPLC-CAD method for the rapid analysis of lipids used in lipid nanoparticles derived from dual centrifugationValentin Bender, L. Yolanda Fuchs, Regine Süss · 2024 · International Journal of Pharmaceutics X
- Study on molecular orientation and stratification in RNA-lipid nanoparticles by cryogenic orbitrap secondary ion mass spectrometryAnna M. Kotowska, Michael W. Fay, Julie A. Watts, Ian S. Gilmore, David J. Scurr, Alaina K. Howe, Vladimı́r Čápka, Corey E. Perez, Devin F. R. Doud, Siddharth Patel et al. · 2025 · Communications Chemistry
- SPICA Force Field for Nucleic Acids and Its Application to Lipid NanoparticlesAkhil Pratap Singh, Hiroki Tanaka, Yusuke Miyazaki, Wataru Shinoda · 2025 · The Journal of Physical Chemistry B
- Self-regulating microfluidic system for lipid nanoparticle productionElena Reus, Johann Savinsky, Simon Wennemaring, Jonas Käsbach, Felix Kerkhoffs, Josef Kehrein, Sebastian Bernhard Rauer, Tessa C. Lühmann, Anna Christina Adams, Matthias Weßling et al. · 2025 · Journal of Controlled Release
- Switchable Lipids: From Conformational Switch to Macroscopic Changes in Lipid VesiclesHuu Trong Phan, Victor Passos Gibson, Aurore Guédin, Emmanuel Ibarboure, Nadia El Mammeri, Axelle Grélard, Jean‐François Le Meins, Érick J. Dufourc, Antoine Loquet, Suzanne Giasson et al. · 2023 · Langmuir
- Genomic analysis in the colon tissues of omega-3 fatty acid-treated rats identifies novel gene signatures implicated in ulcerative colitisJhansi Magisetty, Bhavani Gadiraju, Vijay Kumar Reddy Kondreddy · 2023 · International Journal of Biological Macromolecules
- Delivery of nucleic acid drugs for tumor therapy: Opportunities and challengesDandan Sun, Wenjia Tan, Jianan Zhao, Yafei Tian, Siqi Li, Zhiqi Zhang, Xinzhe Dong, Xiaonan Liu, Na Liu, Ping Jiao et al. · 2024 · Fundamental Research