The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Bioactive Anti-inflammatory, Antibacterial, Antioxidative Silicon-Based Nanofibrous Dressing Enables Cutaneous Tumor Photothermo-Chemo Therapy and Infection-Induced Wound Healing
Abstract
Traditional skin tumor surgery and chronic bacterial-infection-induced wound healing/skin regeneration is still a challenge. The ideal strategy should eliminate the tumor, enhance wound healing/skin formation, and be anti-infection. Herein, we designed a multifunctional elastomeric poly( l -lactic acid)–poly(citrate siloxane)–curcumin@polydopamine hybrid nanofibrous scaffold (denoted as PPCP matrix) for tumor-infection therapy and infection-induced wound healing. The PPCP matrix showed intrinsically multifunctional properties including antioxidative, anti-inflammatory, photothermal, antibacterial, anticancer, and angiogenesis bioactivities. The polydopamine/curcumin presented an excellent near-infrared photothermal/cancer cell toxicity capacity, respectively, which supported PPCP for synergetic skin tumor therapy and antibacterial properties in vitro / in vivo . Additionally, the PPCP nanofibrous matrix significantly promotes the adhesion and proliferation of normal skin cells and accelerates the cutaneous wound healing in normal mice and bacterial-infected mice by enhancing the early angiogenesis. The PPCP nanofibrous matrix with multifunctional bioactivities provides a competitive strategy for skin tumor and bacterial-infection-induced wound healing.
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Cites
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Cited by
Qi, X., Huang, Y., You, S., Xiang, Y., Cai, E., Mao, R., Pan, W., Tong, X., Dong, W., Ye, F., et al. (2022) · Advanced Science · doi:10.1002/advs.202106015 · Cited by 519
Zhou, L., Zheng, H., Liu, Z., Wang, S., Liu, Z., Chen, F., Zhang, H., Kong, J., Zhou, F., & Zhang, Q. (2021) · ACS Nano · doi:10.1021/acsnano.0c06287 · Cited by 382
Multifunctional hydrogels for wound healing: Special focus on biomacromolecular based hydrogels
Asadi, N., Pazoki-Toroudi, H., Del Bakhshayesh, A. R., Akbarzadeh, A., Davaran, S., & Annabi, N. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.12.202 · Cited by 312
Wu, Y., Wang, Y., Zheng, C., Hu, C., Yang, L., Kong, Q., Zhang, H., & Wang, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202305992 · Cited by 156
Xu, J., Fang, H., Zheng, S., Li, L., Jiao, Z., Wang, H., Nie, Y., Liu, T., & Song, K. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.07.162 · Cited by 120
Metadata
- Authors
- Xi, Y., Ge, J., Wang, M., Chen, M., Niu, W., Cheng, W., Xue, Y., Lin, C., & Lei, B.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-02-07
- Volume
- 14
- Issue
- 3
- Pages
- 2904-2916
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W3004561447
- Cited by
- 346
- References
- 57
- FWCI
- 26.37
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Bioactive Anti-inflammatory, Antibacterial, Antioxidative Silicon-Based Nanofibrous Dressing Enables Cutaneous Tumor Photothermo-Chemo Therapy and Infection-Induced Wound Healing. https://app.cochat.ai/papers/10.1021/acsnano.9b07173
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- Xi, Y., Ge, J., Wang, M., Chen, M., Niu, W., Cheng, W., Xue, Y., Lin, C., & Lei, B. (2020). Bioactive Anti-inflammatory, Antibacterial, Antioxidative Silicon-Based Nanofibrous Dressing Enables Cutaneous Tumor Photothermo-Chemo Therapy and Infection-Induced Wound Healing. ACS Nano. https://doi.org/10.1021/acsnano.9b07173
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