The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Metal–Organic Frameworks for Analytical Chemistry: From Sample Collection to Chromatographic Separation
Abstract
In modern analytical chemistry researchers pursue novel materials to meet analytical challenges such as improvements in sensitivity, selectivity, and detection limit. Metal-organic frameworks (MOFs) are an emerging class of microporous materials, and their unusual properties such as high surface area, good thermal stability, uniform structured nanoscale cavities, and the availability of in-pore functionality and outer-surface modification are attractive for diverse analytical applications. This Account summarizes our research on the analytical applications of MOFs ranging from sampling to chromatographic separation. MOFs have been either directly used or engineered to meet the demands of various analytical applications. Bulk MOFs with microsized crystals are convenient sorbents for direct application to in-field sampling and solid-phase extraction. Quartz tubes packed with MOF-5 have shown excellent stability, adsorption efficiency, and reproducibility for in-field sampling and trapping of atmospheric formaldehyde. The 2D copper(II) isonicotinate packed microcolumn has demonstrated large enhancement factors and good shape- and size-selectivity when applied to on-line solid-phase extraction of polycyclic aromatic hydrocarbons in water samples. We have explored the molecular sieving effect of MOFs for the efficient enrichment of peptides with simultaneous exclusion of proteins from biological fluids. These results show promise for the future of MOFs in peptidomics research. Moreover, nanosized MOFs and engineered thin films of MOFs are promising materials as novel coatings for solid-phase microextraction. We have developed an in situ hydrothermal growth approach to fabricate thin films of MOF-199 on etched stainless steel wire for solid-phase microextraction of volatile benzene homologues with large enhancement factors and wide linearity. Their high thermal stability and easy-to-engineer nanocrystals make MOFs attractive as new stationary phases to fabricate MOF-coated capillaries for high-resolution gas chromatography (GC). We have explored a dynamic coating approach to fabricate a MOF-coated capillary for the GC separation of important raw chemicals and persistent organic pollutants with high resolution and excellent selectivity. We have combined a MOF-coated fiber for solid-phase microextraction with a MOF-coated capillary for GC separation, which provides an effective MOF-based tandem molecular sieve platform for selective microextraction and high-resolution GC separation of target analytes in complex samples. Microsized MOFs with good solvent stability are attractive stationary phases for high-performance liquid chromatography (HPLC). These materials have shown high resolution and good selectivity and reproducibility in both the normal-phase HPLC separation of fullerenes and substituted aromatics on MIL-101 packed columns and position isomers on a MIL-53(Al) packed column and the reversed-phase HPLC separation of a wide range of analytes from nonpolar to polar and acidic to basic solutes. Despite the above achievements, further exploration of MOFs in analytical chemistry is needed. Especially, analytical application-oriented engineering of MOFs is imperative for specific applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Functional Porous Coordination Polymers
Kitagawa, S., Kitaura, R., & Noro, S. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200300610 · Cited by 11,071
Reticular synthesis and the design of new materials
Yaghi, O. M., O'Keeffe, M., Ockwig, N. W., Chae, H. K., Eddaoudi, M., & Kim, J. (2003) · Nature · doi:10.1038/nature01650 · Cited by 9,101
Selective gas adsorption and separation in metal–organic frameworks
Li, J.-R., Kuppler, R. J., & Zhou, H.-C. (2009) · Chemical Society Reviews · doi:10.1039/b802426j · Cited by 8,932
Metal–Organic Frameworks for Separations
Li, J.-R., Sculley, J., & Zhou, H.-C. (2012) · Chemical Reviews · doi:10.1021/cr200190s · Cited by 6,323
Hybrid porous solids: past, present, future
Férey, G. (2008) · Chem. Soc. Rev. · doi:10.1039/b618320b · Cited by 5,822
Luminescent Functional Metal–Organic Frameworks
Cui, Y., Yue, Y., Qian, G., & Chen, B. (2012) · Chemical Reviews · doi:10.1021/cr200101d · Cited by 5,697
Eddaoudi, M., Moler, D. B., Li, H., Chen, B., Reineke, T. M., O'Keeffe, M., & Yaghi, O. M. (2001) · Accounts of Chemical Research · doi:10.1021/ar000034b · Cited by 5,180
Nanoscale Metal–Organic Frameworks for Biomedical Imaging and Drug Delivery
Della Rocca, J., Liu, D., & Lin, W. (2011) · Accounts of Chemical Research · doi:10.1021/ar200028a · Cited by 2,087
Metal−Organic Frameworks with Functional Pores for Recognition of Small Molecules
Chen, B., Xiang, S., & Qian, G. (2010) · Accounts of Chemical Research · doi:10.1021/ar100023y · Cited by 2,033
A Microporous Metal–Organic Framework for Gas‐Chromatographic Separation of Alkanes
Chen, B., Liang, C., Yang, J., Contreras, D. S., Clancy, Y. L., Lobkovsky, E. B., Yaghi, O. M., & Dai, S. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200502844 · Cited by 1,238
High Uptakes of CO2 and CH4 in Mesoporous Metal—Organic Frameworks MIL-100 and MIL-101
Llewellyn, P. L., Bourrelly, S., Serre, C., Vimont, A., Daturi, M., Hamon, L., De Weireld, G., Chang, J.-S., Hong, D.-Y., Kyu Hwang, Y., et al. (2008) · Langmuir · doi:10.1021/la800227x · Cited by 1,156
Alaerts, L., Kirschhock, C. E. A., Maes, M., van der Veen, M. A., Finsy, V., Depla, A., Martens, J. A., Baron, G. V., Jacobs, P. A., Denayer, J. F. M., et al. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200700056 · Cited by 538
Pressure-Induced Amorphization and Porosity Modification in a Metal−Organic Framework
Chapman, K. W., Halder, G. J., & Chupas, P. J. (2009) · Journal of the American Chemical Society · doi:10.1021/ja908415z · Cited by 471
Gu, Z., & Yan, X. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200906560 · Cited by 468
Self-citationAlaerts, L., Maes, M., Giebeler, L., Jacobs, P. A., Martens, J. A., Denayer, J. F. M., Kirschhock, C. E. A., & De Vos, D. E. (2008) · Journal of the American Chemical Society · doi:10.1021/ja802761z · Cited by 429
Cui, X.-Y., Gu, Z.-Y., Jiang, D.-Q., Li, Y., Wang, H.-F., & Yan, X.-P. (2009) · Analytical Chemistry · doi:10.1021/ac901663x · Cited by 381
Self-citationChang, N., Gu, Z.-Y., & Yan, X.-P. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1058229 · Cited by 379
Self-citationChiral Metal–Organic Frameworks for High-Resolution Gas Chromatographic Separations
Xie, S.-M., Zhang, Z.-J., Wang, Z.-Y., & Yuan, L.-M. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2044453 · Cited by 322
Finsy, V., Verelst, H., Alaerts, L., De Vos, D., Jacobs, P. A., Baron, G. V., & Denayer, J. F. M. (2008) · Journal of the American Chemical Society · doi:10.1021/ja800686c · Cited by 300
Gu, Z.-Y., Wang, G., & Yan, X.-P. (2010) · Analytical Chemistry · doi:10.1021/ac902450f · Cited by 279
Self-citationChang, N., Gu, Z.-Y., Wang, H.-F., & Yan, X.-P. (2011) · Analytical Chemistry · doi:10.1021/ac2014004 · Cited by 269
Self-citationNuzhdin, A. L., Dybtsev, D. N., Bryliakov, K. P., Talsi, E. P., & Fedin, V. P. (2007) · Journal of the American Chemical Society · doi:10.1021/ja076276p · Cited by 259
Huang, C.-Y., Song, M., Gu, Z.-Y., Wang, H.-F., & Yan, X.-P. (2011) · Environmental Science & Technology · doi:10.1021/es200256q · Cited by 229
Self-citationGu, Z.-Y., Chen, Y.-J., Jiang, J.-Q., & Yan, X.-P. (2011) · Chemical Communications · doi:10.1039/c1cc10579e · Cited by 206
Self-citationChromatography in a Single Metal−Organic Framework (MOF) Crystal
Han, S., Wei, Y., Valente, C., Lagzi, I., Gassensmith, J. J., Coskun, A., Stoddart, J. F., & Grzybowski, B. A. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1074322 · Cited by 196
Ge, D., & Lee, H. K. (2011) · Journal of Chromatography A · doi:10.1016/j.chroma.2011.09.077 · Cited by 194
Gu, Z.-Y., Jiang, D.-Q., Wang, H.-F., Cui, X.-Y., & Yan, X.-P. (2010) · The Journal of Physical Chemistry C · doi:10.1021/jp9063017 · Cited by 186
Self-citationMicroporous Coordination Polymers As Selective Sorbents for Liquid Chromatography
Ahmad, R., Wong-Foy, A. G., & Matzger, A. J. (2009) · Langmuir · doi:10.1021/la902276a · Cited by 183
Liquid phase separations by crystalline microporous coordination polymers
Cychosz, K. A., Ahmad, R., & Matzger, A. J. (2010) · Chemical Science · doi:10.1039/c0sc00144a · Cited by 165
Silica–MOF Composites as a Stationary Phase in Liquid Chromatography
Ameloot, R., Liekens, A., Alaerts, L., Maes, M., Galarneau, A., Coq, B., Desmet, G., Sels, B. F., Denayer, J. F. M., & Vos, D. E. D. (2010) · European Journal of Inorganic Chemistry · doi:10.1002/ejic.201000494 · Cited by 142
Gu, Z., Jiang, J., & Yan, X. (2011) · Analytical Chemistry · doi:10.1021/ac200646w · Cited by 141
Self-citationLuebbers, M. T., Wu, T., Shen, L., & Masel, R. I. (2010) · Langmuir · doi:10.1021/la102582g · Cited by 125
High‐Performance Separation of Fullerenes on Metal–Organic Framework MIL‐101(Cr)
Yang, C., Chen, Y., Wang, H., & Yan, X. (2011) · Chemistry - A European Journal · doi:10.1002/chem.201101593 · Cited by 124
Self-citationMünch, A. S., Seidel, J., Obst, A., Weber, E., & Mertens, F. O. R. L. (2011) · Chemistry - A European Journal · doi:10.1002/chem.201100642 · Cited by 79
Barreto, A. S., Silva, R. L. D., Silva, S. C. G. D. S., Rodrigues, M. O., Simone, C. A. D., de Sá, G. F., Alves, S., Navickiene, S., & de Mesquita, M. E. (2010) · Journal of Separation Science · doi:10.1002/jssc.201000553 · Cited by 61
Separation of Chemical Reaction Intermediates by Metal–Organic Frameworks
Centrone, A., Santiso, E. E., & Hatton, T. A. (2011) · Small · doi:10.1002/smll.201100098 · Cited by 52
Cited by
Metal–Organic Frameworks for Separation
Zhao, X., Wang, Y., Li, D., Bu, X., & Feng, P. (2018) · Advanced Materials · doi:10.1002/adma.201705189 · Cited by 1,305
Li, X., Zhang, L., Yang, Z., Wang, P., Yan, Y., & Ran, J. (2020) · Separation and Purification Technology · doi:10.1016/j.seppur.2019.116213 · Cited by 1,048
Metal–Organic Frameworks for Air Purification of Toxic Chemicals
DeCoste, J. B., & Peterson, G. W. (2014) · Chemical Reviews · doi:10.1021/cr4006473 · Cited by 958
The ten principles of green sample preparation
López-Lorente, Á. I., Pena-Pereira, F., Pedersen-Bjergaard, S., Zuin, V. G., Ozkan, S. A., & Psillakis, E. (2022) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2022.116530 · Cited by 721
Functional materials derived from open framework templates/precursors: synthesis and applications
Sun, J.-K., & Xu, Q. (2014) · Energy & Environmental Science · doi:10.1039/c4ee00517a · Cited by 687
Metadata
- Authors
- Gu, Z.-Y., Yang, C.-X., Chang, N., & Yan, X.-P.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-03-12
- Volume
- 45
- Issue
- 5
- Pages
- 734-745
- ISSN
- 0001-4842 (ISSN-L)
- 1520-4898
- OpenAlex
- W2013080921
- Cited by
- 674
- References
- 36
- FWCI
- 66.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
