Nanotechnology for a Safe and Sustainable Water Supply: Enabling Integrated Water Treatment and Reuse
Abstract
Ensuring reliable access to clean and affordable water is one of the greatest global challenges of this century. As the world's population increases, water pollution becomes more complex and difficult to remove, and global climate change threatens to exacerbate water scarcity in many areas, the magnitude of this challenge is rapidly increasing. Wastewater reuse is becoming a common necessity, even as a source of potable water, but our separate wastewater collection and water supply systems are not designed to accommodate this pressing need. Furthermore, the aging centralized water and wastewater infrastructure in the developed world faces growing demands to produce higher quality water using less energy and with lower treatment costs. In addition, it is impractical to establish such massive systems in developing regions that currently lack water and wastewater infrastructure. These challenges underscore the need for technological innovation to transform the way we treat, distribute, use, and reuse water toward a distributed, differential water treatment and reuse paradigm (i.e., treat water and wastewater locally only to the required level dictated by the intended use). Nanotechnology offers opportunities to develop next-generation water supply systems. This Account reviews promising nanotechnology-enabled water treatment processes and provides a broad view on how they could transform our water supply and wastewater treatment systems. The extraordinary properties of nanomaterials, such as high surface area, photosensitivity, catalytic and antimicrobial activity, electrochemical, optical, and magnetic properties, and tunable pore size and surface chemistry, provide useful features for many applications. These applications include sensors for water quality monitoring, specialty adsorbents, solar disinfection/decontamination, and high performance membranes. More importantly, the modular, multifunctional and high-efficiency processes enabled by nanotechnology provide a promising route both to retrofit aging infrastructure and to develop high performance, low maintenance decentralized treatment systems including point-of-use devices. Broad implementation of nanotechnology in water treatment will require overcoming the relatively high costs of nanomaterials by enabling their reuse and mitigating risks to public and environmental health by minimizing potential exposure to nanoparticles and promoting their safer design. The development of nanotechnology must go hand in hand with environmental health and safety research to alleviate unintended consequences and contribute toward sustainable water management.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Except for magnetic nanoparticles, separating the majority of exhausted nanoparticles from the purified water for subsequent reuse remains a difficult effort.
“Additionally, except for magnetic nanoparticles, separating the majority of exhausted nanoparticles from the purified water for subsequent reuse remains a difficult effort.109,110”
From Emerging nanotechnology approaches for sustainable water treatment and heavy metals removal: a comprehensive review (2025) · cites this paper as [110]
Cites
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Nie, S., & Emory, S. R. (1997) · Science · doi:10.1126/science.275.5303.1102 · Cited by 10,260 · see citing works
Science and technology for water purification in the coming decades
Shannon, M. A., Bohn, P. W., Elimelech, M., Georgiadis, J. G., Mariñas, B. J., & Mayes, A. M. (2008) · Nature · doi:10.1038/nature06599 · Cited by 8,479 · see citing works
The Future of Seawater Desalination: Energy, Technology, and the Environment
Elimelech, M., & Phillip, W. A. (2011) · Science · doi:10.1126/science.1200488 · Cited by 6,775 · see citing works
TiO2 photocatalysis and related surface phenomena
FUJISHIMA, A., ZHANG, X., & TRYK, D. (2008) · Surface Science Reports · doi:10.1016/j.surfrep.2008.10.001 · Cited by 6,737 · see citing works
Electrospinning of Nanofibers: Reinventing the Wheel?
Li, D., & Younan Xia, A. (2004) · Advanced Materials · doi:10.1002/adma.200400719 · Cited by 5,541 · see citing works
Recent developments in photocatalytic water treatment technology: A review
Chong, M. N., Jin, B., Chow, C. W. K., & Saint, C. (2010) · Water Research · doi:10.1016/j.watres.2010.02.039 · Cited by 5,386 · see citing works
Ni, M., Leung, M. K. H., Leung, D. Y. C., & Sumathy, K. (2005) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2005.01.009 · Cited by 4,145 · see citing works
Anatase TiO2 single crystals with a large percentage of reactive facets
Yang, H. G., Sun, C., Qiao, S., Zou, J., Liu, G., Smith, S. C., Cheng, H., & Lu, G. Q. (2008) · Nature · doi:10.1038/nature06964 · Cited by 4,104 · see citing works
Pal, S., Tak, Y. K., & Song, J. M. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02218-06 · Cited by 4,042 · see citing works
Fast Mass Transport Through Sub-2-Nanometer Carbon Nanotubes
Holt, J. K., Park, H. G., Wang, Y., et al. (2006) · Science · doi:10.1126/science.1126298 · Cited by 3,025 · see citing works
Liu, S., Zeng, T. H., Hofmann, M., Burcombe, E., Wei, J., Jiang, R., Kong, J., & Chen, Y. (2011) · ACS Nano · doi:10.1021/nn202451x · Cited by 2,936 · see citing works
Nanomaterials in the environment: Behavior, fate, bioavailability, and effects
Klaine, S. J., Alvarez, P. J. J., Batley, G. E., Fernandes, T. F., Handy, R. D., Lyon, D. Y., Mahendra, S., McLaughlin, M. J., & Lead, J. R. (2008) · Environmental Toxicology and Chemistry · doi:10.1897/08-090.1 · Cited by 2,772 · see citing works
Self-citationWu, X., Liu, H., Liu, J., Haley, K. N., Treadway, J. A., Larson, J., Ge, N., Peale, F., & Bruchez, M. P. (2002) · Nature Biotechnology · doi:10.1038/nbt764 · Cited by 2,506 · see citing works
Li, Q., Mahendra, S., Lyon, D. Y., Brunet, L., Liga, M. V., Li, D., & Alvarez, P. J. J. (2008) · Water Research · doi:10.1016/j.watres.2008.08.015 · Cited by 2,386 · see citing works
Self-citationSize matters: why nanomaterials are different
Roduner, E. (2006) · Chemical Society Reviews · doi:10.1039/b502142c · Cited by 2,356 · see citing works
A review of water treatment membrane nanotechnologies
Pendergast, M. M., & Hoek, E. M. V. (2011) · Energy & Environmental Science · doi:10.1039/c0ee00541j · Cited by 2,084 · see citing works
Nanoscale iron particles for environmental remediation: An overview
Zhang, W.-X. (2003) · Journal of Nanoparticle Research · doi:10.1023/a:1025520116015 · Cited by 2,003 · see citing works
Environmental Applications of Carbon-Based Nanomaterials
Mauter, M. S., & Elimelech, M. (2008) · Environmental Science & Technology · doi:10.1021/es8006904 · Cited by 1,576 · see citing works
Toxicity of Silver Nanoparticles to Chlamydomonas reinhardtii
Navarro, E., Piccapietra, F., Wagner, B., Marconi, F., Kaegi, R., Odžak, N., Sigg, L., & Behra, R. (2008) · Environmental Science & Technology · doi:10.1021/es801785m · Cited by 1,457 · see citing works
Carbon Nanomaterials in Biosensors: Should You Use Nanotubes or Graphene?
Yang, W. R., Ratinac, K. R., Ringer, S. P., Thordarson, P., Gooding, J. J., & Braet, F. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200903463 · Cited by 1,432 · see citing works
Role of Particle Size in Nanocrystalline TiO 2 -Based Photocatalysts
Zhang, Z., Wang, C.-C., Zakaria, R., & Ying, J. Y. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp982948+ · Cited by 1,427 · see citing works
Interfacial polymerization of thin film nanocomposites: A new concept for reverse osmosis membranes
Jeong, B., Hoek, E. M. V., Yan, Y. S., et al. (2007) · Journal of Membrane Science · doi:10.1016/j.memsci.2007.02.025 · Cited by 1,316 · see citing works
Adsorption Mechanisms of Organic Chemicals on Carbon Nanotubes
Pan, B., & Xing, B. (2008) · Environmental Science & Technology · doi:10.1021/es801777n · Cited by 1,263 · see citing works
Low-Field Magnetic Separation of Monodisperse Fe 3 O 4 Nanocrystals
Yavuz, C. T., Mayo, J. T., Yu, W. W., Prakash, A., Falkner, J. C., Yean, S., Cong, L., Shipley, H. J., Kan, A. T., Tomson, M. B., et al. (2006) · Science · doi:10.1126/science.1131475 · Cited by 1,253 · see citing works
Climatic Impact of Tropical Lowland Deforestation on Nearby Montane Cloud Forests
Lawton, R. O., Nair, U. S., Pielke, R. A., & Welch, R. M. (2001) · Science · doi:10.1126/science.1062459 · Cited by 1,169 · see citing works
Assessing the Risks of Manufactured Nanomaterials
Wiesner, M. R., Lowry, G. V., Alvarez, P. J. J., Dionysiou, D., & Biswas, P. (2006) · Environmental Science & Technology · doi:10.1021/es062726m · Cited by 1,162 · see citing works
Self-citationSorption of divalent metal ions from aqueous solution by carbon nanotubes: A review
RAO, G., Lu, C., & Su, F. (2006) · Separation and Purification Technology · doi:10.1016/j.seppur.2006.12.006 · Cited by 1,040 · see citing works
Water Permeation Across Biological Membranes: Mechanism and Dynamics of Aquaporin-1 and GlpF
de Groot, B. L., & Grubmüller, H. (2001) · Science · doi:10.1126/science.1066115 · Cited by 914 · see citing works
Yang, K., & Xing, B. (2010) · Chemical Reviews · doi:10.1021/cr100059s · Cited by 863 · see citing works
Progress on sanitation and drinking-water 2010 update
worl (2010) · Cited by 831 · see citing works
Self‐Organized TiO 2 Nanotube Layers as Highly Efficient Photocatalysts
Macák, J. M., Zlámal, M., Krýsa, J., et al. (2007) · Small · doi:10.1002/smll.200600426 · Cited by 815 · see citing works
Ji, L., Chen, W., Duan, L., & Zhu, D. (2009) · Environmental Science & Technology · doi:10.1021/es803268b · Cited by 801 · see citing works
Nanotechnology and Water Treatment: Applications and Emerging Opportunities
Theron, J., Walker, J. A., & Cloete, T. E. (2008) · Critical Reviews in Microbiology · doi:10.1080/10408410701710442 · Cited by 722 · see citing works
Nanotechnology and in Situ Remediation: A Review of the Benefits and Potential Risks
Karn, B., Kuiken, T., & Otto, M. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900793 · Cited by 721 · see citing works
Kumar, M., Grzelakowski, M., Zilles, J. L., Clark, M. M., & Meier, W. P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708762104 · Cited by 717 · see citing works
Kikuchi, Y., Sunada, K., Iyoda, T., Hashimoto, K., & Fujishima, A. (1997) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/s1010-6030(97)00038-5 · Cited by 647 · see citing works
Polymeric Biomaterials with Degradation Sites for Proteases Involved in Cell Migration
West, J. L., & Hubbell, J. A. (1998) · Macromolecules · doi:10.1021/ma981296k · Cited by 627 · see citing works
Xiu, Z., Ma, J., & Alvarez, P. J. J. (2011) · Environmental Science & Technology · doi:10.1021/es201918f · Cited by 521 · see citing works
Self-citationElectronic-Structure-Dependent Bacterial Cytotoxicity of Single-Walled Carbon Nanotubes
Vecitis, C. D., Zodrow, K. R., Kang, S., et al. (2010) · ACS Nano · doi:10.1021/nn101558x · Cited by 521 · see citing works
Engineered Graphite Oxide Materials for Application in Water Purification
Gao, W., Majumder, M., Alemany, L. B., Narayanan, T. N., Ibarra, M. A., Pradhan, B. K., & Ajayan, P. M. (2011) · ACS Applied Materials & Interfaces · doi:10.1021/am200300u · Cited by 391 · see citing works
Physicochemical Determinants of Multiwalled Carbon Nanotube Bacterial Cytotoxicity
Kang, S., Mauter, M. S., & Elimelech, M. (2008) · Environmental Science & Technology · doi:10.1021/es8010173 · Cited by 390 · see citing works
Electrochemical Multiwalled Carbon Nanotube Filter for Viral and Bacterial Removal and Inactivation
Vecitis, C. D., Schnoor, M. H., Rahaman, M. S., Schiffman, J. D., & Elimelech, M. (2011) · Environmental Science & Technology · doi:10.1021/es2000062 · Cited by 379 · see citing works
Tiraferri, A., Vecitis, C. D., & Elimelech, M. (2011) · ACS Applied Materials & Interfaces · doi:10.1021/am200536p · Cited by 358 · see citing works
In vivo Biomodification of Lipid-Coated Carbon Nanotubes by Daphnia magna
Roberts, A. P., Mount, A. S., Seda, B., Souther, J., Qiao, R., Lin, S., Ke, P. C., Rao, A. M., & Klaine, S. J. (2007) · Environmental Science & Technology · doi:10.1021/es062572a · Cited by 326 · see citing works
Rahaman, M. S., Vecitis, C. D., & Elimelech, M. (2011) · Environmental Science & Technology · doi:10.1021/es203607d · Cited by 282 · see citing works
Nanomaterial Enabled Biosensors for Pathogen Monitoring - A Review
Vikesland, P. J., & Wigginton, K. R. (2010) · Environmental Science & Technology · doi:10.1021/es903704z · Cited by 269 · see citing works
The stability of polymeric membranes in a TiO2 photocatalysis process
Chin, S. S., Chiang, K., & Fane, A. G. (2005) · Journal of Membrane Science · doi:10.1016/j.memsci.2005.09.033 · Cited by 251 · see citing works
Designing biomimetic antifouling surfaces
Salta, M. M., Wharton, J. A., Stoodley, P., Dennington, S., Goodes, L. R., Werwinski, S., Mart, U., Wood, R. J. K., & Stokes, K. R. (2010) · Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences · doi:10.1098/rsta.2010.0195 · Cited by 222 · see citing works
Auffan, M., Rose, J., Proux, O., et al. (2008) · Langmuir · doi:10.1021/la702998x · Cited by 213 · see citing works
Eckelman, M. J., Mauter, M. S., Isaacs, J., et al. (2012) · Environmental Science & Technology · doi:10.1021/es203409a · Cited by 200 · see citing works
Viewpoint: Formulating the Problems for Environmental Risk Assessment of Nanomaterials
HANDY, R. O. A. R. (2007) · Environmental Science & Technology · doi:10.1021/es072598h · Cited by 144 · see citing works
Chen, C.-Y., & Jafvert, C. T. (2011) · Carbon · doi:10.1016/j.carbon.2011.07.029 · Cited by 123 · see citing works
Laccase-Carrying Electrospun Fibrous Membranes for Adsorption and Degradation of PAHs in Shoal Soils
Dai, Y., Yin, L., & Niu, J. (2011) · Environmental Science & Technology · doi:10.1021/es203286e · Cited by 121 · see citing works
Lee, J., Hong, S. W., Mackeyev, Y., et al. (2011) · Environmental Science & Technology · doi:10.1021/es2029944 · Cited by 120 · see citing works
Mauter, M. S., Elimelech, M., & Osuji, C. O. (2010) · ACS Nano · doi:10.1021/nn102047j · Cited by 95 · see citing works
Continuous High-Yield Production of Vertically Aligned Carbon Nanotubes on 2D and 3D Substrates
de Villoria, R. G., Hart, A. J., & Wardle, B. L. (2011) · ACS Nano · doi:10.1021/nn2008645 · Cited by 90 · see citing works
C60 Aminofullerene Immobilized on Silica as a Visible-Light-Activated Photocatalyst
Lee, J., Mackeyev, Y., Cho, M., et al. (2010) · Environmental Science & Technology · doi:10.1021/es1028475 · Cited by 84 · see citing works
Public Health and Infectious Diseases
(2016) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781782621676-00107 · Cited by 17 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Applications of nanotechnology in water and wastewater treatment
Qu, X., Alvarez, P. J. J., & Li, Q. (2013) · Water Research · doi:10.1016/j.watres.2012.09.058 · Cited by 2,444 · see citing works
Self-citationRemediation of wastewater using various nano-materials
Anjum, M., Miandad, R., Waqas, M., Gehany, F., & Barakat, M. A. (2019) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2016.10.004 · Cited by 779 · see citing works
Nanomaterials-enabled water and wastewater treatment
Zhang, Y., Wu, B., Xu, H., Liu, H., Wang, M., He, Y., & Pan, B. (2016) · NanoImpact · doi:10.1016/j.impact.2016.09.004 · Cited by 417 · see citing works
Amusat, S. O., Kebede, T. G., Dube, S., & Nindi, M. M. (2021) · Journal of Water Process Engineering · doi:10.1016/j.jwpe.2021.101993 · Cited by 323 · see citing works
Heidarizad, M., & Şengör, S. S. (2016) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2016.09.049 · Cited by 177 · see citing works
Nanotechnology-based water quality management for wastewater treatment
Madhura, L., Singh, S., Kanchi, S., Sabela, M., Bisetty, K., & Inamuddin (2019) · Environmental Chemistry Letters · doi:10.1007/s10311-018-0778-8 · Cited by 167 · see citing works
Strategically engineering advanced nanomaterials for heavy-metal remediation from wastewater
Sable, H., Kumar, V., Singh, V., Rustagi, S., Chahal, S., & Chaudhary, V. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216079 · Cited by 134 · see citing works
Nanoadsorbents for wastewater treatment: next generation biotechnological solution
Ali, M. E., Hoque, M. E., Safdar Hossain, S. K., & Biswas, M. C. (2020) · International Journal of Environmental Science and Technology · doi:10.1007/s13762-020-02755-4 · Cited by 120 · see citing works
Hussein, E. B., Rasheed, F. A., Mohammed, A. S., & Kayani, K. F. (2025) · RSC Advances · doi:10.1039/d5ra06914a · Cited by 86 · see citing works
“109,110 Furthermore, much is still to learn about how nanomaterials behave and what happens during water and wastewater treatment.”
Assessing low quality water use policy framework: case study from Ghana
Amponsah, O., Vigre, H., Schou, T. W., Boateng, E. S., Braimah, I., & Abaidoo, R. C. (2015) · Resources, Conservation and Recycling · doi:10.1016/j.resconrec.2015.01.009 · Cited by 34 · see citing works
Waste Water Remediation and Nanoadsorbents
Patel, P. K., Singh, H. K., & Singh, A. (2025) · Advances in Wastewater Research · doi:10.1007/978-981-96-3908-3_10 · Cited by 9 · see citing works
- Authors
- Qu, X., Brame, J., Li, Q., & Alvarez, P. J. J.
- Affiliations
- Rice University (US)
- Corresponding author
- Li, Qilin
- Alvarez, Pedro J. J.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 2012-06-27
- Volume
- 46
- Issue
- 3
- Pages
- 834-843
- ISSN
- 0001-4842 (ISSN-L)
- 1520-4898
- OpenAlex
- W1970446300
- Cited by
- 799
- References
- 58
- Citations by year
- 2026: 38 · 2025: 52 · 2024: 74 · 2023: 76 · 2022: 74 · 2021: 107 · 2020: 60 · 2019: 57 · 2018: 67 · 2017: 54 · 2016: 52 · 2015: 40 · 2014: 31 · 2013: 14 · 2012: 1
- FWCI
- 49.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Accounts of Chemical Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Waste Management and Disposal › Wastewater Treatment and Reuse
- Physical Sciences › Environmental Science › Water Science and Technology › Membrane Separation Technologies
- Physical Sciences › Engineering › Biomedical Engineering › Environmental remediation with nanomaterials
- Keywords
- nanotechnology, water treatment, water reuse, nanomaterials, water quality sensors, adsorbents, solar disinfection, membranes, decentralized water treatment, point-of-use treatment, aging water infrastructure, nanoparticle safety, sustainable water management, water scarcity, water pollution
- MeSH terms
- Conservation of Natural Resources, Safety, Water Supply, Water Purification, Nanotechnology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review