From Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New Chemistry
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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFrom Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New ChemistryRichard K. Haynes and Simone C. VonwillerView Author Information Department of Chemistry, Hong Kong University of Science and Technology, Kowloon, Hong Kong, and School of Chemistry, University of Sydney, New South Wales 2006, AustraliaCite this: Acc. Chem. Res. 1997, 30, 2, 73–79Publication Date (Web):February 13, 1997Publication History Received17 September 1996Published online13 February 1997Published inissue 1 February 1997https://pubs.acs.org/doi/10.1021/ar950058whttps://doi.org/10.1021/ar950058wresearch-articleACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views757Altmetric-Citations193LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Antimicrobial agents,Crystal cleavage,Oxides,Oxygen,Reaction products Get e-Alerts
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In vitro experiments have shown that 481 can undergo spontaneous conversion to a transient enol as proposed in step ii).
“These in vitro experiments have shown that 481 can indeed undergo sponataneous conversion to a transient enol as proposed in step ii) of Scheme 11 [204,238,243,302,303]”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [204]
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The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
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Brown, G. D. (2003) · Phytochemistry Reviews · doi:10.1023/b:phyt.0000004199.43295.64 · Cited by 16 · see citing works
- Authors
- Haynes, R. K., & Vonwiller, S. C.
- Affiliations
- The University of Sydney (AU)
- ORCID
- Haynes, Richard K.
- Venue
- Accounts of Chemical Research
- Publisher
- American Chemical Society (ACS)
- Published
- 1997-02-01
- Volume
- 30
- Issue
- 2
- Pages
- 73-79
- ISSN
- 0001-4842 (ISSN-L)
- 1520-4898
- OpenAlex
- W2953144752
- Cited by
- 220
- References
- 26
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 3 · 2018: 3 · 2017: 6 · 2016: 2 · 2015: 2 · 2014: 1 · 2013: 4 · 2012: 12
- FWCI
- 4.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Accounts of Chemical Research (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical compounds biological activities
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Keywords
- artemisinin, artemisinin derivatives, trioxane, antimalarial drugs, crystal cleavage, reaction products, medicinal plants, history of chemistry
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