13C-2H correlation NMR spectroscopy studies of the in vivo transformations of natural products from Artemisia annua
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The tertiary allylic hydroperoxide 481 is a biosynthetic intermediate linking dihydroartemisinic acid (480) and artemisinin (495), as shown by in vivo experiments with labeled dihydroartemisinic acid (480).
“The tertiary allylic hydroperoxide 481, which is produced in step i), has already been shown to be a biosynthetic intermediate, linking dihydroartemisinic acid (480) and artemisinin (495), by in vivo experiments with labeled dihydroartemisinic acid (480) [185,189].”
From The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao) (2010) · cites this paper as [189]
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The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
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- Authors
- Brown, G. D.
- Affiliations
- University of Reading (GB)
- Corresponding author
- Brown, G.D.
- ORCID
- Brown, G.D.
- Venue
- Phytochemistry Reviews
- Published
- 2003-01
- Volume
- 2
- Issue
- 1-2
- Pages
- 45-59
- ISSN
- 1568-7767 (ISSN-L)
- 1572-980X
- OpenAlex
- W2089419525
- Cited by
- 16
- References
- 17
- Citations by year
- 2023: 1 · 2015: 2 · 2014: 1 · 2013: 1
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Phytochemistry Reviews (publishedVersion)
- Funders
- University Grants Committee
- University of Hong Kong
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Physical Sciences › Chemistry › Spectroscopy › Advanced NMR Techniques and Applications
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Sesquiterpenes and Asteraceae Studies
- Keywords
- Artemisia annua, artemisinin biosynthesis, dihydroartemisinic acid, autoxidation
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