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Cited by 197

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Regenerative Biomaterials that “Click”: Simple, Aqueous-Based Protocols for Hydrogel Synthesis, Surface Immobilization, and 3D Patterning

Nimmo, Chelsea M., Shoichet, Molly S.·2011·Bioconjugate Chemistry

Abstract

The click chemistry era has generated a library of versatile "spring-loaded" reactions that offer high yields, regio- and stereospecificity, and outstanding functional group tolerance. These powerful transformations are particularly advantageous for the design of sophisticated biomaterials that require high levels of precision and control, namely, materials that promote tissue regeneration such as hydrogels, 2D functionalized substrates, and 3D biomimetic scaffolds. In this review, the synthesis and application of regenerative biomaterials via click chemistry are summarized. Particular emphasis is placed on the copper(I)-catalyzed alkyne-azide cycloaddition, Diels-Alder cycloadditions, and thiol-click coupling.

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Metadata

Authors
Nimmo, C. M., & Shoichet, M. S.
Venue
Bioconjugate Chemistry
Published
2011-10-26
Volume
22
Issue
11
Pages
2199-2209
ISSN
  • 1043-1802 (ISSN-L)
  • 1520-4812
OpenAlex
W1992831737
Cited by
197
References
5
FWCI
8.23
Type
journal article
Language
en
Open access
closed

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