Bile acid biosynthesis

Russell, David W., Setchell, Kenneth D. R.·1992·Biochemistry

Cited by (817)

Items 101–200 of 817

  1. Expression Cloning of an Oxysterol 7α-Hydroxylase Selective for 24-Hydroxycholesterol
    Jia Li-Hawkins, Erik G. Lund, Amy D. Bronson, David W. Russell · 2000 · Journal of Biological Chemistry
  2. Clinical and molecular diagnosis of cerebrotendinous xanthomatosis with a review of the mutations in the CYP27A1 gene
    Gian Nicola Gallus, Maria Teresa Dotti, Antonio Federico · 2006 · Neurological Sciences
  3. Circulating microRNAs involved in multiple sclerosis
    Sue Rutherford Siegel, Jason Mackenzie, George Chaplin, Nina G. Jablonski, Lyn Robyn Griffiths · 2012 · Molecular Biology Reports
  4. Nuclear receptor regulation of cholesterol and bile acid metabolism
    Joyce J. Repa, David J. Mangelsdorf · 1999 · Current Opinion in Biotechnology
  5. Bile acids: analysis in biological fluids and tissues
    William James Griffiths, Jan Sjövall · 2009 · Journal of Lipid Research
  6. Nuclear receptors in bile acid metabolism
    Li, Tiangang, Chiang, John Y. L. · 2013 · Drug Metabolism Reviews
  7. REGULATION OF BILE ACID BIOSYNTHESIS
    Z. Reno Vlahčevič, WM Pandak, R. Todd Stravitz · 1999 · Gastroenterology Clinics of North America
  8. Liver disease caused by failure to racemize trihydroxycholestanoic acid: Gene mutation and effect of bile acid therapy
    Kenneth D.R. Setchell, James E. Heubi, Kevin E. Bove, Nancy C. O’Connell, Tracy Brewsaugh, Steven J. Steinberg, Ann B. Moser, Robert H. Squires · 2003 · Gastroenterology
  9. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: A microarray study
    Nick Fletcher, David Wahlström, Rebecca Lundberg, Charlotte B. Nilsson, Kerstin C. Nilsson, Kenneth Stockling, Heike Hellmold, Helen Håkansson · 2005 · Toxicology and Applied Pharmacology
  10. Disorders of bile acid synthesis
    Peter Theodore Clayton · 2011 · Journal of Inherited Metabolic Disease
  11. Cholesterol in health and disease
    Ira A. Tabas · 2002 · Journal of Clinical Investigation
  12. Bile Acid Induction of Cytokine Expression by Macrophages Correlates with Repression of Hepatic Cholesterol 7α-Hydroxylase
    Jon H. Miyake, Shui-Long Wang, Roger A. Davis · 2000 · Journal of Biological Chemistry
  13. Emerging roles of the intestine in control of cholesterol metabolism
    Janine K. Kruit · 2006 · World Journal of Gastroenterology
  14. The Role of PPAR α Activation in Liver and Muscle
    Lena Burri, G. Hege Thoresen, Rolf Kristian Berge · 2010 · PPAR Research
  15. Inborn Errors of Bile Acid Metabolism
    James E. Heubi, Kenneth D.R. Setchell, Kevin E. Bove · 2007 · Seminars in Liver Disease
  16. Intestinal Bile Acid Transport: Biology, Physiology, and Pathophysiology
    Benjamin L. Shneider · 2001 · Journal of Pediatric Gastroenterology and Nutrition
  17. Bile Acid Signaling in Liver Metabolism and Diseases
    Tiangang Li, John Y.L. Chiang · 2011 · Journal of Lipids
  18. Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNA
    Margrit Schwarz, Erik G. Lund, Richard Lathe, Ingemar Björkhem, David W. Russell · 1997 · Journal of Biological Chemistry
  19. Alternate pathways of bile acid synthesis in the cholesterol 7α-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding
    Margrit Schwarz, David W. Russell, John M. Dietschy, Stephen D. Turley · 2001 · Journal of Lipid Research
  20. Bile Acid Synthetic Defects and Liver Disease: A Comprehensive Review
    Kevin E. Bove, James E. Heubi, William F. Balistreri, Kenneth D.R. Setchell · 2002 · Pediatric and Developmental Pathology
  21. Regulation of Hepatic 7α-Hydroxylase Expression and Response to Dietary Cholesterol in the Rat and Hamster
    Jay D. Horton, Jennifer A. Cuthbert, David K. Spady · 1995 · Journal of Biological Chemistry
  22. Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptors
    Maurizio Crestani, Azita Sadeghpour, Diane Stroup, Giovanni Galli, John Y.L. Chiang · 1998 · Journal of Lipid Research
  23. Bile acids: analysis in biological fluids and tissues
    William James Griffiths, Jan Sjövall · 2009 · Journal of Lipid Research
  24. Mechanisms of disease: inborn errors of bile acid synthesis
    Sundaram, Shikha S, Bove, Kevin E, Lovell, Mark A, Sokol, Ronald J · 2008 · Nature Clinical Practice Gastroenterology & Hepatology
  25. Formation of cholesterol oxidation products (COPs) in animal products
    Sun Jin Hur, G.B. Park, Seon-Tea Joo · 2006 · Food Control
  26. Intravenous apoA-I/lecithin discs increase pre-β-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans
    M. Nazeem Nanjee, C. Justin Cooke, Roy A. Garvin, Francesca J. Semeria, Gary F. Lewis, Waldemar Lech Olszewski, N.E. Miller · 2001 · Journal of Lipid Research
  27. Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.
    Lee R. Hagey, D L Crombie, E. Espinosa, Martin C. Carey, Hirotsune Igimi, AF Hofmann · 1993 · Journal of Lipid Research
  28. Nuclear Receptors as Targets for Drug Development: Regulation of Cholesterol and Bile Acid Metabolism by Nuclear Receptors
    Makoto Makishima · 2005 · Journal of Pharmacological Sciences
  29. Biochemistry of peroxisomes in health and disease
    Inderjit Singh · 1997 · Molecular and Cellular Biochemistry
  30. The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
    Monica D. Chow, Yi‐Horng Lee, Grace Liejun Guo · 2017 · Molecular Aspects of Medicine
  31. Cloning and expression of cDNA of human Δ<sup>4</sup>‐3‐oxosteroid 5β‐reductase and substrate specificity of the expressed enzyme
    KONDO, Kazu‐Hiro, KAI, Masa‐Hiro, SETOGUCHI, Yoshiko, EGGERTSEN, Gösta, SJÖBLOM, Peter, SETOGUCHI, Toshiaki, OKUDA, Kyu‐Ichiro, BJÖRKHEM, Ingemar · 1994 · European Journal of Biochemistry
  32. Why Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) Progression
    Aline Gottlieb, Ali E. Canbay · 2019 · Cells
  33. FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice
    Henning Wittenburg, Malcolm A. Lyons, Renhua Li, Gary A. Churchill, Martin C. Carey, Beverly J. Paigen · 2003 · Gastroenterology
  34. Defects in Bile Acid Biosynthesis‐Diagnosis and Treatment
    Kenneth D.R. Setchell, James E. Heubi · 2006 · Journal of Pediatric Gastroenterology and Nutrition
  35. Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
    Verena Hiebl, Angela Ladurner, Simone L. Latkolik, Verena Maria Dirsch · 2018 · Biotechnology Advances
  36. Liver Organoids: Recent Developments, Limitations and Potential
    Sean Philip Harrison, Saphira Baumgarten, Rajneesh Verma, Oleg Lunov, Alexandr Dejneka, Gareth J. Sullivan · 2021 · Frontiers in Medicine
  37. Gene Expression Profiling in Wild-Type and PPAR-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPAR-Independent Effects
    Mitchell B. Rosen, J Schmid, J. Christopher Corton, ROBERT D. JUN. ZEHR, Kaberi P. Das, Barbara D. Abbott, Christopher S. Lau · 2010 · PPAR Research
  38. LXRα is the dominant regulator of CYP7A1 transcription
    Seema Gupta, William M. Pandak, Phillip B. Hylemon · 2002 · Biochemical and Biophysical Research Communications
  39. FXR, a Bile Acid Receptor and Biological Sensor
    Hua Tu · 2000 · Trends in Cardiovascular Medicine
  40. Multiple Factors Regulate the Rat Liver Basolateral Sodium-dependent Bile Acid Cotransporter Gene Promoter
    Saul J. Karpen, An–Qiang Sun, Bela Kudish, Bruno Hagenbuch, Peter J. Meier, Meenakshisundaram Ananthanarayanan, Frederick J. Suchy · 1996 · Journal of Biological Chemistry
  41. “Don't Know Much Bile-ology”
    Ajay Chawla, Enrique Sáez, Ronald M. Evans · 2000 · Cell
  42. Canalicular ABC transporters and liver disease
    Michael Nicolaou, Edward J. Andress, Joseph Krisjanis Zolnerciks, Peter H. Dixon, Catherine Williamson, Kenneth J. Linton · 2011 · The Journal of Pathology
  43. The SLC10 Carrier Family
    Barbara Döring, Thomas Lütteke, Joachim Geyer, Ernst Petzinger · 2012 · Current topics in membranes
  44. Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin–proteasomal degradation
    Ji Miao, Zhen Xiao, Deepthi Kanamaluru, Gyesik Min, Peter M. Yau, Timothy D. Veenstra, Ewa C. S. Ellis, Steve Strom, Kelly M. Suino-Powell, H. Eric Xu et al. · 2009 · Genes & Development
  45. Liver X Receptor (LXR) Regulation of the LXRα Gene in Human Macrophages
    Whitney, Karl D., Watson, Michael A., Goodwin, Bryan, Galardi, Cristin M., Maglich, Jodi M., Wilson, Joan G., Willson, Timothy M., Collins, Jon L., Kliewer, Steven A. · 2001 · Journal of Biological Chemistry
  46. Pectin Feeding Influences Fecal Bile Acid Excretion, Hepatic Bile Acid and Cholesterol Synthesis and Serum Cholesterol in Rats
    Fructuoso Garcia‐Diez, Victoria Garcia-Mediavilla, J.E. Bayón, Javier González‐Gallego · 1996 · Journal of Nutrition
  47. Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal disease
    Amanda B. Blake, Blake C. Guard, Julia B. Honneffer, Jonathan A. Lidbury, Jörg M. Steiner, Jan S. Suchodolski · 2019 · PLoS ONE
  48. A new cause of progressive intrahepatic cholestasis: 3β-Hydroxy-C27-steroid dehydrogenase/isomerase deficiency
    Emmanuel Jacquemin, Kenneth D.R. Setchell, Nancy C. O’Connell, O. Bernard · 1994 · The Journal of Pediatrics
  49. The role of the gut microbiota in health and cardiovascular diseases
    Lu Wang, Shiqi Wang, Qing Zhang, Chengqi He, Chenying Fu, Quan Wei · 2022 · Molecular Biomedicine
  50. Bile acids and their receptors in regulation of gut health and diseases
    Sen Lin, Sutian Wang, Peng Wang, Cuiming Tang, Zhenjiang Wang, Lian Chen, Guoqing Luo, Hong Chen, Yuntao Liu, Bin Feng et al. · 2022 · Progress in Lipid Research
  51. Drying of probiotics to enhance the viability during preparation, storage, food application, and digestion: A review
    Anyi Wang, Qixin Zhong · 2023 · Comprehensive Reviews in Food Science and Food Safety
  52. Protective role of puerarin on lead-induced alterations of the hepatic glutathione antioxidant system and hyperlipidemia in rats
    Chan‐Min Liu, Jie‐Qiong Ma, Yun-Zhi Sun · 2011 · Food and Chemical Toxicology
  53. New insights into the fatty acid-binding protein (FABP) family in the small intestine
    Philippe Besnard, Isabelle Niot, Hélène Poirier, Lionel C. Clément, André Bernard · 2002 · Molecular and Cellular Biochemistry
  54. Thyroid Hormone Receptor β-Deficient Mice Show Complete Loss of the Normal Cholesterol 7α-Hydroxylase (CYP7A) Response to Thyroid Hormone but Display Enhanced Resistance to Dietary Cholesterol
    Hjalmar Gullberg, Mats Rudling, Douglas Forrest, B. Angelin, Björn Vennström · 2000 · Molecular Endocrinology
  55. Δ4-3-Oxosteroid 5β-reductase deficiency causing neonatal liver failure and hemochromatosis
    Benjamin L. Shneider, Kenneth D.R. Setchell, Peter F. Whitington, Kathryn A. Neilson, Frederick J. Suchy · 1994 · The Journal of Pediatrics
  56. Enhanced Expression of the Human Multidrug Resistance Protein 3 by Bile Salt in Human Enterocytes
    Akihiko Inokuchi, Eiji Hinoshita, Yukihide Iwamoto, Kimitoshi Kohno, Michihiko Kuwano, Takeshi Uchiumi · 2001 · Journal of Biological Chemistry
  57. Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets
    Stephen D. Turley, Margrit Schwarz, David K. Spady, John M. Dietschy · 1998 · Hepatology
  58. Quantitation of the Pool of Cholesterol Associated with Acyl-CoA:Cholesterol Acyltransferase in Human Fibroblasts
    Yvonne Lange, Theodore L. Steck · 1997 · Journal of Biological Chemistry
  59. Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol.
    David K. Spady, Jennifer A. Cuthbert, M N Willard, R S Meidell · 1995 · Journal of Clinical Investigation
  60. Reciprocal Regulation of a Glucocorticoid Receptor-Steroidogenic Factor-1 Transcription Complex on the Dax-1 Promoter by Glucocorticoids and Adrenocorticotropic Hormone in the Adrenal Cortex
    Gummow, Brian M., Scheys, Joshua O., Cancelli, Victoria R., Hammer, Gary D. · 2006 · Molecular Endocrinology
  61. Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in mice
    Joshua D. Chandler, Xin Yang Hu, Eun‐Ju Ko, Soojin Park, Young‐Tae Lee, Michael L. Orr, Jolyn Fernandes, Karan Uppal, Sang‐Moo Kang, Dean P. Jones et al. · 2016 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  62. Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.
    Laurie A. Drozdowski, Tom MT Clandinin, Alan B.R. Thomson · 2010 · PubMed Central
  63. The bile acid synthetic gene 3β-hydroxy-Δ5-C27-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis
    Margrit Schwarz, Angelique C. Wright, Daphne L. Davis, Hisham M. Nazer, Ingemar Björkhem, David W. Russell · 2000 · Journal of Clinical Investigation
  64. FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption
    Diana Jung, Takeshi Inagaki, Robert D. Gerard, Paul A. Dawson, Steven A. Kliewer, David J. Mangelsdorf, Antonio Moschetta · 2007 · Journal of Lipid Research
  65. Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11–q12
    Jonathan C. Cohen, James J. Cali, Diane F. Jelinek, Margarete Mehrabian, Robert S. Sparkes, Aldons Jake Lusis, David W. Russell, Helen H. Hobbs · 1992 · Genomics
  66. Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study
    Varma, Vijay R., Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C., Oommen, Anup M., Roberts, Jackson A. et al. · 2021 · PLOS Medicine
  67. Nuclear bile acid signaling through the farnesoid X receptor
    Claire Mazuy, Audrey Helleboid‐Chapman, Bart Staels, Philippe Lefèbvre · 2014 · Cellular and Molecular Life Sciences
  68. Oxidized plant sterols in human serum and lipid infusions as measured by combined gas-liquid chromatography-mass spectrometry
    Jogchum Plat, Harald Brzezinka, Dieter Lütjohann, Ronald P. Mensink, Klaus von Bergmann · 2001 · Journal of Lipid Research
  69. Association of the A-204C polymorphism in the cholesterol 7α-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study
    Patrick Couture, James D. Otvos, L. Adrienne Cupples, Peter W.F. Wilson, Ernst J. Schaefer, José María Ordovás · 1999 · Journal of Lipid Research
  70. Independent Repression of Bile Acid Synthesis and Activation of c-Jun N-terminal Kinase (JNK) by Activated Hepatocyte Fibroblast Growth Factor Receptor 4 (FGFR4) and Bile Acids
    Chundong Yu, Fen Wang, Chengliu Jin, Xinqiang Huang, Wallace L. McKeehan · 2005 · Journal of Biological Chemistry
  71. Two 7α‐hydroxylase enzymes in bile acid biosynthesis
    Margrit Schwarz, Erik G. Lund, David W. Russell · 1998 · Current Opinion in Lipidology
  72. Down-regulation of hepatic LDL receptor expression in experimental nephrosis
    Nosratola D. Vaziri, Kai Hui Liang · 1996 · Kidney International
  73. Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys.
    L L Rudel, C Deckelman, M Wilson, Martin Scobey, Richard A. Anderson · 1994 · Journal of Clinical Investigation
  74. Regulation of hepatic 7 alpha-hydroxylase expression by dietary psyllium in the hamster.
    Jay D. Horton, Jennifer A. Cuthbert, David K. Spady · 1994 · Journal of Clinical Investigation
  75. Hypolipidemic Effects of Citrus bergamia Risso et Poiteau Juice in Rats Fed a Hypercholesterolemic Diet
    Natalizia Miceli, Maria Rita Mondello, Maria Teresa Monforte, V. Sdrafkakis, Paola Dugo, Maria Lucia Crupi, Maria Fernanda Taviano, R. De Pasquale, Ada Trovato · 2007 · Journal of Agricultural and Food Chemistry
  76. Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosis
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  77. Update on Progressive Familial Intrahepatic Cholestasis
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  78. Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome
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  79. Effects of dietary supplemental bile acids on performance, carcass characteristics, serum lipid metabolites and intestinal enzyme activities of broiler chickens
    Wenqing Lai, Weigang Huang, Bing Dong, Aizhi Cao, Wenjuan Zhang, Juntao Li, Hui Wu, Liying Zhang · 2017 · Poultry Science
  80. Feedback Regulation of Bile Acid Synthesis in Primary Human Hepatocytes: Evidence That Cdca Is the Strongest Inhibitor
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  81. Molecular features of bile salt hydrolases and relevance in human health
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  82. Mechanisms of Interactions between Bile Acids and Plant Compounds—A Review
    Susanne Naumann, Dirk Haller, Peter Eisner, Ute Schweiggert‐Weisz · 2020 · International Journal of Molecular Sciences
  83. Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid
    Magnus Axelson, Ewa C. S. Ellis, Birgitta Mörk, Kristina Garmark, Anna Abrahamsson, Ingemar Björkhem, Bo‐Göran Ericzon, Curt Einarsson · 2000 · Hepatology
  84. Monogenic Dyslipidemias: Window on Determinants of Plasma Lipoprotein Metabolism
    Robert Alexander Hegele · 2001 · The American Journal of Human Genetics
  85. Feed-forward Regulation of Bile Acid Detoxification by CYP3A4
    Catherine Stedman, Graham R Robertson, Sally Coulter, Christopher Liddle · 2004 · Journal of Biological Chemistry
  86. Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice☆☆☆
    Peter J. Voshol, Rick Havinga, Henk Wolters, R. Ottenhoff, Hans M. G. Princen, Ronald P.J. Oude Elferink, Albert Kornelis Groen, Folkert Kuipers · 1998 · Gastroenterology
  87. Micellar solubilisation of cholesterol is essential for absorption in humans
    L A Woollett, Y Wang, D D Buckley, L Yao, S Chin, N Granholm, P J H Jones, Kenneth D.R. Setchell, P Tso, J E Heubi · 2006 · Gut
  88. Determination of bile salt critical micellization concentration on the road to drug discovery
    Benedetto Natalini, Roccaldo Sardella, Antimo Gioiello, Federica Ianni, Alessandro Di Michele, Maura Marinozzi · 2013 · Journal of Pharmaceutical and Biomedical Analysis
  89. Resolution of liver biopsy alterations in three siblings with bile acid treatment of an inborn error of bile acid metabolism (Δ4-3-oxosteroid 5β-reductase deficiency)
    Ynthia C. Daugherty, Kenneth D.R. Setchell, James E. Heubi, William F. Ballstreri · 1993 · Hepatology
  90. The biosynthesis of steroids and triterpenoids
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  91. Bile acid-based therapies for non-alcoholic steatohepatitis and alcoholic liver disease
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    Qingfeng Luo, Lan Sun, Jianyong Si, Di‐Hua Chen · 2008 · Phytomedicine
  93. Induction of hepatic ABC transporter expression is part of the PPARα–mediated fasting response in the mouse
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  94. The Murine and Human Cholesterol 7α-Hydroxylase Gene Promoters Are Differentially Responsive to Regulation by Fatty Acids Mediated via Peroxisome Proliferator-activated Receptor α
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  95. Enzymatic routes for the synthesis of ursodeoxycholic acid
    Thorsten Eggert, Daniel Bakonyi, Werner Hummel · 2014 · Journal of Biotechnology
  96. Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.
    Y. H. Lee, Julia A. Alberta, Frank J. Gonzalez, David J. Waxman · 1994 · Journal of Biological Chemistry
  97. Sterol 27-Hydroxylase Acts on 7-Ketocholesterol in Human Atherosclerotic Lesions and Macrophages in Culture
    Andrew John Brown, Gerald Francis Watts, John R. Burnett, Roger Thornton Dean, Wendy Jessup · 2000 · Journal of Biological Chemistry
  98. The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase gene
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  99. Inborn Errors of Bile Acid Metabolism
    James E. Heubi, Kenneth D.R. Setchell, Kevin E. Bove · 2018 · Clinics in Liver Disease
  100. In Vitro Interactions of Dietary Fibre Enriched Food Ingredients with Primary and Secondary Bile Acids
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