Bile acid biosynthesis
Russell, David W., Setchell, Kenneth D. R.·1992·Biochemistry
Cited by (817)
Items 101–200 of 817
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- Bile Acid Signaling in Liver Metabolism and DiseasesTiangang Li, John Y.L. Chiang · 2011 · Journal of Lipids
- Identification and Characterization of a Mouse Oxysterol 7α-Hydroxylase cDNAMargrit Schwarz, Erik G. Lund, Richard Lathe, Ingemar Björkhem, David W. Russell · 1997 · Journal of Biological Chemistry
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- Regulation of Hepatic 7α-Hydroxylase Expression and Response to Dietary Cholesterol in the Rat and HamsterJay D. Horton, Jennifer A. Cuthbert, David K. Spady · 1995 · Journal of Biological Chemistry
- Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptorsMaurizio Crestani, Azita Sadeghpour, Diane Stroup, Giovanni Galli, John Y.L. Chiang · 1998 · Journal of Lipid Research
- Bile acids: analysis in biological fluids and tissuesWilliam James Griffiths, Jan Sjövall · 2009 · Journal of Lipid Research
- Mechanisms of disease: inborn errors of bile acid synthesisSundaram, Shikha S, Bove, Kevin E, Lovell, Mark A, Sokol, Ronald J · 2008 · Nature Clinical Practice Gastroenterology & Hepatology
- Formation of cholesterol oxidation products (COPs) in animal productsSun Jin Hur, G.B. Park, Seon-Tea Joo · 2006 · Food Control
- Intravenous apoA-I/lecithin discs increase pre-β-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humansM. Nazeem Nanjee, C. Justin Cooke, Roy A. Garvin, Francesca J. Semeria, Gary F. Lewis, Waldemar Lech Olszewski, N.E. Miller · 2001 · Journal of Lipid Research
- Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.Lee R. Hagey, D L Crombie, E. Espinosa, Martin C. Carey, Hirotsune Igimi, AF Hofmann · 1993 · Journal of Lipid Research
- Nuclear Receptors as Targets for Drug Development: Regulation of Cholesterol and Bile Acid Metabolism by Nuclear ReceptorsMakoto Makishima · 2005 · Journal of Pharmacological Sciences
- Biochemistry of peroxisomes in health and diseaseInderjit Singh · 1997 · Molecular and Cellular Biochemistry
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- Cloning and expression of cDNA of human Δ<sup>4</sup>‐3‐oxosteroid 5β‐reductase and substrate specificity of the expressed enzymeKONDO, Kazu‐Hiro, KAI, Masa‐Hiro, SETOGUCHI, Yoshiko, EGGERTSEN, Gösta, SJÖBLOM, Peter, SETOGUCHI, Toshiaki, OKUDA, Kyu‐Ichiro, BJÖRKHEM, Ingemar · 1994 · European Journal of Biochemistry
- Why Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) ProgressionAline Gottlieb, Ali E. Canbay · 2019 · Cells
- FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in miceHenning Wittenburg, Malcolm A. Lyons, Renhua Li, Gary A. Churchill, Martin C. Carey, Beverly J. Paigen · 2003 · Gastroenterology
- Defects in Bile Acid Biosynthesis‐Diagnosis and TreatmentKenneth D.R. Setchell, James E. Heubi · 2006 · Journal of Pediatric Gastroenterology and Nutrition
- Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXRVerena Hiebl, Angela Ladurner, Simone L. Latkolik, Verena Maria Dirsch · 2018 · Biotechnology Advances
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- LXRα is the dominant regulator of CYP7A1 transcriptionSeema Gupta, William M. Pandak, Phillip B. Hylemon · 2002 · Biochemical and Biophysical Research Communications
- FXR, a Bile Acid Receptor and Biological SensorHua Tu · 2000 · Trends in Cardiovascular Medicine
- Multiple Factors Regulate the Rat Liver Basolateral Sodium-dependent Bile Acid Cotransporter Gene PromoterSaul J. Karpen, An–Qiang Sun, Bela Kudish, Bruno Hagenbuch, Peter J. Meier, Meenakshisundaram Ananthanarayanan, Frederick J. Suchy · 1996 · Journal of Biological Chemistry
- “Don't Know Much Bile-ology”Ajay Chawla, Enrique Sáez, Ronald M. Evans · 2000 · Cell
- Canalicular ABC transporters and liver diseaseMichael Nicolaou, Edward J. Andress, Joseph Krisjanis Zolnerciks, Peter H. Dixon, Catherine Williamson, Kenneth J. Linton · 2011 · The Journal of Pathology
- The SLC10 Carrier FamilyBarbara Döring, Thomas Lütteke, Joachim Geyer, Ernst Petzinger · 2012 · Current topics in membranes
- Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin–proteasomal degradationJi Miao, Zhen Xiao, Deepthi Kanamaluru, Gyesik Min, Peter M. Yau, Timothy D. Veenstra, Ewa C. S. Ellis, Steve Strom, Kelly M. Suino-Powell, H. Eric Xu et al. · 2009 · Genes & Development
- Liver X Receptor (LXR) Regulation of the LXRα Gene in Human MacrophagesWhitney, Karl D., Watson, Michael A., Goodwin, Bryan, Galardi, Cristin M., Maglich, Jodi M., Wilson, Joan G., Willson, Timothy M., Collins, Jon L., Kliewer, Steven A. · 2001 · Journal of Biological Chemistry
- Pectin Feeding Influences Fecal Bile Acid Excretion, Hepatic Bile Acid and Cholesterol Synthesis and Serum Cholesterol in RatsFructuoso Garcia‐Diez, Victoria Garcia-Mediavilla, J.E. Bayón, Javier González‐Gallego · 1996 · Journal of Nutrition
- Altered microbiota, fecal lactate, and fecal bile acids in dogs with gastrointestinal diseaseAmanda B. Blake, Blake C. Guard, Julia B. Honneffer, Jonathan A. Lidbury, Jörg M. Steiner, Jan S. Suchodolski · 2019 · PLoS ONE
- A new cause of progressive intrahepatic cholestasis: 3β-Hydroxy-C27-steroid dehydrogenase/isomerase deficiencyEmmanuel Jacquemin, Kenneth D.R. Setchell, Nancy C. O’Connell, O. Bernard · 1994 · The Journal of Pediatrics
- The role of the gut microbiota in health and cardiovascular diseasesLu Wang, Shiqi Wang, Qing Zhang, Chengqi He, Chenying Fu, Quan Wei · 2022 · Molecular Biomedicine
- Bile acids and their receptors in regulation of gut health and diseasesSen Lin, Sutian Wang, Peng Wang, Cuiming Tang, Zhenjiang Wang, Lian Chen, Guoqing Luo, Hong Chen, Yuntao Liu, Bin Feng et al. · 2022 · Progress in Lipid Research
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- New insights into the fatty acid-binding protein (FABP) family in the small intestinePhilippe Besnard, Isabelle Niot, Hélène Poirier, Lionel C. Clément, André Bernard · 2002 · Molecular and Cellular Biochemistry
- Thyroid Hormone Receptor β-Deficient Mice Show Complete Loss of the Normal Cholesterol 7α-Hydroxylase (CYP7A) Response to Thyroid Hormone but Display Enhanced Resistance to Dietary CholesterolHjalmar Gullberg, Mats Rudling, Douglas Forrest, B. Angelin, Björn Vennström · 2000 · Molecular Endocrinology
- Δ4-3-Oxosteroid 5β-reductase deficiency causing neonatal liver failure and hemochromatosisBenjamin L. Shneider, Kenneth D.R. Setchell, Peter F. Whitington, Kathryn A. Neilson, Frederick J. Suchy · 1994 · The Journal of Pediatrics
- Enhanced Expression of the Human Multidrug Resistance Protein 3 by Bile Salt in Human EnterocytesAkihiko Inokuchi, Eiji Hinoshita, Yukihide Iwamoto, Kimitoshi Kohno, Michihiko Kuwano, Takeshi Uchiumi · 2001 · Journal of Biological Chemistry
- Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol dietsStephen D. Turley, Margrit Schwarz, David K. Spady, John M. Dietschy · 1998 · Hepatology
- Quantitation of the Pool of Cholesterol Associated with Acyl-CoA:Cholesterol Acyltransferase in Human FibroblastsYvonne Lange, Theodore L. Steck · 1997 · Journal of Biological Chemistry
- Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterol.David K. Spady, Jennifer A. Cuthbert, M N Willard, R S Meidell · 1995 · Journal of Clinical Investigation
- Reciprocal Regulation of a Glucocorticoid Receptor-Steroidogenic Factor-1 Transcription Complex on the Dax-1 Promoter by Glucocorticoids and Adrenocorticotropic Hormone in the Adrenal CortexGummow, Brian M., Scheys, Joshua O., Cancelli, Victoria R., Hammer, Gary D. · 2006 · Molecular Endocrinology
- Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in miceJoshua D. Chandler, Xin Yang Hu, Eun‐Ju Ko, Soojin Park, Young‐Tae Lee, Michael L. Orr, Jolyn Fernandes, Karan Uppal, Sang‐Moo Kang, Dean P. Jones et al. · 2016 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology.Laurie A. Drozdowski, Tom MT Clandinin, Alan B.R. Thomson · 2010 · PubMed Central
- The bile acid synthetic gene 3β-hydroxy-Δ5-C27-steroid oxidoreductase is mutated in progressive intrahepatic cholestasisMargrit Schwarz, Angelique C. Wright, Daphne L. Davis, Hisham M. Nazer, Ingemar Björkhem, David W. Russell · 2000 · Journal of Clinical Investigation
- FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorptionDiana Jung, Takeshi Inagaki, Robert D. Gerard, Paul A. Dawson, Steven A. Kliewer, David J. Mangelsdorf, Antonio Moschetta · 2007 · Journal of Lipid Research
- Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11–q12Jonathan C. Cohen, James J. Cali, Diane F. Jelinek, Margarete Mehrabian, Robert S. Sparkes, Aldons Jake Lusis, David W. Russell, Helen H. Hobbs · 1992 · Genomics
- Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic studyVarma, Vijay R., Wang, Youjin, An, Yang, Varma, Sudhir, Bilgel, Murat, Doshi, Jimit, Legido-Quigley, Cristina, Delgado, João C., Oommen, Anup M., Roberts, Jackson A. et al. · 2021 · PLOS Medicine
- Nuclear bile acid signaling through the farnesoid X receptorClaire Mazuy, Audrey Helleboid‐Chapman, Bart Staels, Philippe Lefèbvre · 2014 · Cellular and Molecular Life Sciences
- Oxidized plant sterols in human serum and lipid infusions as measured by combined gas-liquid chromatography-mass spectrometryJogchum Plat, Harald Brzezinka, Dieter Lütjohann, Ronald P. Mensink, Klaus von Bergmann · 2001 · Journal of Lipid Research
- Association of the A-204C polymorphism in the cholesterol 7α-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring StudyPatrick Couture, James D. Otvos, L. Adrienne Cupples, Peter W.F. Wilson, Ernst J. Schaefer, José María Ordovás · 1999 · Journal of Lipid Research
- Independent Repression of Bile Acid Synthesis and Activation of c-Jun N-terminal Kinase (JNK) by Activated Hepatocyte Fibroblast Growth Factor Receptor 4 (FGFR4) and Bile AcidsChundong Yu, Fen Wang, Chengliu Jin, Xinqiang Huang, Wallace L. McKeehan · 2005 · Journal of Biological Chemistry
- Two 7α‐hydroxylase enzymes in bile acid biosynthesisMargrit Schwarz, Erik G. Lund, David W. Russell · 1998 · Current Opinion in Lipidology
- Down-regulation of hepatic LDL receptor expression in experimental nephrosisNosratola D. Vaziri, Kai Hui Liang · 1996 · Kidney International
- Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys.L L Rudel, C Deckelman, M Wilson, Martin Scobey, Richard A. Anderson · 1994 · Journal of Clinical Investigation
- Regulation of hepatic 7 alpha-hydroxylase expression by dietary psyllium in the hamster.Jay D. Horton, Jennifer A. Cuthbert, David K. Spady · 1994 · Journal of Clinical Investigation
- Hypolipidemic Effects of Citrus bergamia Risso et Poiteau Juice in Rats Fed a Hypercholesterolemic DietNatalizia Miceli, Maria Rita Mondello, Maria Teresa Monforte, V. Sdrafkakis, Paola Dugo, Maria Lucia Crupi, Maria Fernanda Taviano, R. De Pasquale, Ada Trovato · 2007 · Journal of Agricultural and Food Chemistry
- Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosisNosratola D. Vaziri, Tadashi Sato, Kaihui Liang · 2003 · Kidney International
- Update on Progressive Familial Intrahepatic CholestasisFeras Alissa, Ronald Jaffe, Benjamin L. Shneider · 2008 · Journal of Pediatric Gastroenterology and Nutrition
- Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolomeSamuel J. Bowers, Fernando Vargas, Antonio González, Shannon He, Peng Jiang, Pieter C. Dorrestein, Rob D. Knight, Kenneth P. Wright, Christopher A. Lowry, Monika Fleshner et al. · 2020 · PLoS ONE
- Effects of dietary supplemental bile acids on performance, carcass characteristics, serum lipid metabolites and intestinal enzyme activities of broiler chickensWenqing Lai, Weigang Huang, Bing Dong, Aizhi Cao, Wenjuan Zhang, Juntao Li, Hui Wu, Liying Zhang · 2017 · Poultry Science
- Feedback Regulation of Bile Acid Synthesis in Primary Human Hepatocytes: Evidence That Cdca Is the Strongest InhibitorEwa C. S. Ellis, Magnus Axelson, Anna Abrahamsson, Gösta Eggertsen, Anders Thörne, Grzegorz Nowak, Bo‐Göran Ericzon, Ingemar Björkhem, Curt Einarsson · 2003 · Hepatology
- Molecular features of bile salt hydrolases and relevance in human healthDeepak Chand, Vellore Sunder Avinash, Yashpal Yadav, Archana Vishnu Pundle, Cheravakattu Gopalan Suresh, Sureshkumar Ramasamy · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Mechanisms of Interactions between Bile Acids and Plant Compounds—A ReviewSusanne Naumann, Dirk Haller, Peter Eisner, Ute Schweiggert‐Weisz · 2020 · International Journal of Molecular Sciences
- Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acidMagnus Axelson, Ewa C. S. Ellis, Birgitta Mörk, Kristina Garmark, Anna Abrahamsson, Ingemar Björkhem, Bo‐Göran Ericzon, Curt Einarsson · 2000 · Hepatology
- Monogenic Dyslipidemias: Window on Determinants of Plasma Lipoprotein MetabolismRobert Alexander Hegele · 2001 · The American Journal of Human Genetics
- Feed-forward Regulation of Bile Acid Detoxification by CYP3A4Catherine Stedman, Graham R Robertson, Sally Coulter, Christopher Liddle · 2004 · Journal of Biological Chemistry
- Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice☆☆☆Peter J. Voshol, Rick Havinga, Henk Wolters, R. Ottenhoff, Hans M. G. Princen, Ronald P.J. Oude Elferink, Albert Kornelis Groen, Folkert Kuipers · 1998 · Gastroenterology
- Micellar solubilisation of cholesterol is essential for absorption in humansL A Woollett, Y Wang, D D Buckley, L Yao, S Chin, N Granholm, P J H Jones, Kenneth D.R. Setchell, P Tso, J E Heubi · 2006 · Gut
- Determination of bile salt critical micellization concentration on the road to drug discoveryBenedetto Natalini, Roccaldo Sardella, Antimo Gioiello, Federica Ianni, Alessandro Di Michele, Maura Marinozzi · 2013 · Journal of Pharmaceutical and Biomedical Analysis
- Resolution of liver biopsy alterations in three siblings with bile acid treatment of an inborn error of bile acid metabolism (Δ4-3-oxosteroid 5β-reductase deficiency)Ynthia C. Daugherty, Kenneth D.R. Setchell, James E. Heubi, William F. Ballstreri · 1993 · Hepatology
- The biosynthesis of steroids and triterpenoidsGeoffrey D. Brown · 1998 · Natural Product Reports
- Bile acid-based therapies for non-alcoholic steatohepatitis and alcoholic liver diseaseTiangang Li, John Y.L. Chiang · 2020 · HepatoBiliary Surgery and Nutrition
- Hypocholesterolemic effect of stilbenes containing extract-fraction from Cajanus cajan L. on diet-induced hypercholesterolemia in miceQingfeng Luo, Lan Sun, Jianyong Si, Di‐Hua Chen · 2008 · Phytomedicine
- Induction of hepatic ABC transporter expression is part of the PPARα–mediated fasting response in the mouseTineke Kok, Henk Wolters, Vincent W. Bloks, Rick Havinga, Peter L. M. Jansen, Bart Staels, Folkert Kuipers · 2003 · Gastroenterology
- The Murine and Human Cholesterol 7α-Hydroxylase Gene Promoters Are Differentially Responsive to Regulation by Fatty Acids Mediated via Peroxisome Proliferator-activated Receptor αSukhinder Kaur Cheema, Luis B. Agellon · 2000 · Journal of Biological Chemistry
- Enzymatic routes for the synthesis of ursodeoxycholic acidThorsten Eggert, Daniel Bakonyi, Werner Hummel · 2014 · Journal of Biotechnology
- Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.Y. H. Lee, Julia A. Alberta, Frank J. Gonzalez, David J. Waxman · 1994 · Journal of Biological Chemistry
- Sterol 27-Hydroxylase Acts on 7-Ketocholesterol in Human Atherosclerotic Lesions and Macrophages in CultureAndrew John Brown, Gerald Francis Watts, John R. Burnett, Roger Thornton Dean, Wendy Jessup · 2000 · Journal of Biological Chemistry
- The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase geneDilip D. Patel, Brian L. Knight, Anne K. Soutar, Geoffrey F. Gibbons, David P. Wade · 2000 · Biochemical Journal
- Inborn Errors of Bile Acid MetabolismJames E. Heubi, Kenneth D.R. Setchell, Kevin E. Bove · 2018 · Clinics in Liver Disease
- In Vitro Interactions of Dietary Fibre Enriched Food Ingredients with Primary and Secondary Bile AcidsSusanne Naumann, Ute Schweiggert‐Weisz, Julia Eglmeier, Dirk Haller, Peter Eisner · 2019 · Nutrients