Bile acid biosynthesis

Russell, David W., Setchell, Kenneth D. R.·1992·Biochemistry

DOI 10.1021/bi00135a001

Cited by (817)

Items 201–300 of 817

Crystal Structure of Human Liver Δ4-3-Ketosteroid 5β-Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis
Di Costanzo, Luigi, Drury, Jason E., Penning, Trevor M., Christianson, David W. · 2008 · Journal of Biological Chemistry
Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation
Tomofumi Fujino, Mizuho Une, Tsuneo Imanaka, Kazuhide Inoue, Tomoko Nishimaki‐Mogami · 2004 · Journal of Lipid Research
Glucose stimulates cholesterol 7α-hydroxylase gene transcription in human hepatocytes
Tiangang Li, Dipanjan Chanda, Yanqiao Zhang, Hueng‐Sik Choi, John Y.L. Chiang · 2009 · Journal of Lipid Research
Dietary Cholesterol Fails to Stimulate the Human Cholesterol 7α-Hydroxylase Gene (CYP7A1) in Transgenic Mice
Luis B. Agellon, Victor A. B. Drover, Sukhinder Kaur Cheema, Franck G. Gbaguidi, A Walsh · 2002 · Journal of Biological Chemistry
BILE ACID TRANSPORT
Ron Bahar, Andrew Stolz · 1999 · Gastroenterology Clinics of North America
Intracellular transport of bile acids
Luis B. Agellon, Enrique C. Torchia · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Role of bile acids in the regulation of the metabolic pathways
Taoka, Hiroki, Yokoyama, Yoko, Morimoto, Kohkichi, Kitamura, Naho, Tanigaki, Tatsuya, Takashina, Yoko, Tsubota, Kazuo, Watanabe, Mitsuhiro · 2016 · World Journal of Diabetes
Acquired lecithin-cholesterol acyltransferase deficiency in nephrotic syndrome
Nostratola D. Vaziri, K. Liang, John S. Parks · 2001 · American Journal of Physiology-Renal Physiology
Bile Acid Signaling in Metabolic and Inflammatory Diseases and Drug Development
Tiangang Li, John Y.L. Chiang · 2024 · Pharmacological Reviews
Stress responses in lactic acid bacteria
Maarten van de Guchte, Pascale Serror, Christian Chervaux, Tamara Smokvina, Stanislav Dusko Ehrlich, Emmanuelle Maguin · 2002 · Springer eBooks
Hepatic HMG-CoA reductase gene expression during the course of puromycin-induced nephrosis
Nosratola D. Vaziri, Kai Hui Liang · 1995 · Kidney International
New insights into bile acid transport
Martha W. Love, Paul A. Dawson · 1998 · Current Opinion in Lipidology
Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C
Gunvor Alvélius, Ola Hjalmarson, William James Griffiths, Ingemar Björkhem, Jan Sjövall · 2001 · Journal of Lipid Research
Overexpression of Cholesterol 7α-Hydroxylase (CYP7A) in Mice Lacking the Low Density Lipoprotein (LDL) Receptor Gene
David K. Spady, Jennifer A. Cuthbert, Maureen N. Willard, R S Meidell · 1998 · Journal of Biological Chemistry
Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes
R. Todd Stravitz, Zdravko R. Vlahcevic, T.L. Russell, Marcia L. Heizer, Narayan G. Avadhani, Phillip B. Hylemon · 1996 · The Journal of Steroid Biochemistry and Molecular Biology
Dietary fats modulate the regulatory potential of dietary cholesterol on cholesterol 7 alpha-hydroxylase gene expression
Sukhinder Kaur Cheema, D Cikaluk, Luis B. Agellon · 1997 · Journal of Lipid Research
A liver‐specific gene expression panel predicts the differentiation status of in vitro hepatocyte models
Dae‐Soo Kim, Jea‐Woon Ryu, Mi‐Young Son, Jung‐Hwa Oh, Kyung‐Sook Chung, Sugi Lee, Jeong‐Ju Lee, Junho Ahn, Ju‐Sik Min, Jiwon Ahn et al. · 2017 · Hepatology
Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat.
Mats J. Rudling, Paolo Parini, Bo Angelin · 1997 · Journal of Clinical Investigation
Sterol Regulatory Element‐Binding Proteins (SREBPs) as Regulators of Lipid Metabolism
Hyoun-Ju Kim, Makoto Miyazaki, Weng Chi Man, James Mukasa Ntambi · 2002 · Annals of the New York Academy of Sciences
Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home
Michael L. Fitzgerald, Kathryn J. Moore, Mason Wright Freeman · 2002 · Journal of Molecular Medicine
An analysis of the use of dogs in predicting human toxicology and drug safety
Bailey, Jarrod, Thew, Michelle, Balls, Michael · 2013 · Alternatives to Laboratory Animals
The pharmacological exploitation of cholesterol 7α-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol
Federica Gilardi, Nico Mitro, Cristina Godio, Elena Scotti, Donatella Caruso, Maurizio Crestani, Emma De Fabiani · 2007 · Pharmacology & Therapeutics
Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7α-hydroxylase
William M. Pandak, Z. Reno Vlahčevič, Douglas M. Heuman, Kaye S. Redford, John Y.L. Chiang, Philip B. Hylemon · 1994 · Hepatology
Translocator Protein (18 kDa) as a Target for Novel Anxiolytics with a Favourable Side‐Effect Profile
Caroline Nothdurfter, Gerhard Rammes, Thomas C. Baghai, Cornelius Schüle, Michaël Schumacher, Vassilios Papadopoulos, Rainer Rupprecht · 2011 · Journal of Neuroendocrinology
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Koshi Hashimoto, Ronald Cohen, Masanobu Yamada, Kathleen R. Markan, Tsuyoshi Monden, Teturou Satoh, Masatomo Mori, Fredric Edward Wondisford · 2005 · Journal of Biological Chemistry
Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).
B S Korn, Iichiro Shimomura, Yuriy K. Bashmakov, Robert E. Hammer, Jay D. Horton, Joseph L. Goldstein, M S Brown · 1998 · Journal of Clinical Investigation
Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.
María I. Ramirez, Denise Karaoglu, Diego Haro, Carmen Barillas, Roya Bashirzadeh, Gregorio Gil · 1994 · Molecular and Cellular Biology
The nuclear bile acid receptor FXR is activated by PGC-1α in a ligand-dependent manner
Eiko Nakagawa Kanaya, Takuma Shiraki, Hisato Jingami · 2004 · Biochemical Journal
Expression of sterol 12α-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo
William M. Pandak, Patricia M. Bohdan, Clifton V. Franklund, Darrell H. Mallonee, Gösta Eggertsen, Ingemar Björkhem, Gregorio Gil, Z. Reno Vlahčevič, Phillip B. Hylemon · 2001 · Gastroenterology
Glucagon and cAMP inhibit cholesterol 7α‐hydroxylase (CYP7a1) gene expression in human hepatocytes
Kwang‐Hoon Song, John Y.L. Chiang · 2005 · Hepatology
The binding of cholesterol and bile salts to recombinant rat liver fatty acid-binding protein
Alfred E. A. THUMSER, David C. Wilton · 1996 · Biochemical Journal
Development and Validation of a Highly Sensitive LC-MS/MS Method for the Analysis of Bile Acids in Serum, Plasma, and Liver Tissue Samples
Cristina Gómez, Simon Stücheli, Denise V. Kratschmar, Jamal Bouitbir, Alex Odermatt · 2020 · Metabolites
Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor
Tomoko Nishimaki‐Mogami, Mizuho Une, Tomofumi Fujino, Yoji Sato, Norimasa Tamehiro, Yosuke Kawahara, Koichi Shudo, Kazuhide Inoue · 2004 · Journal of Lipid Research
Bile acids and lipoprotein metabolism: Effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression
L.-M. Nilsson, A. Abrahamsson, Staffan Sahlin, Ulf O Gustafsson, Bo Angelin, Paolo Parini, Curt Einarsson · 2007 · Biochemical and Biophysical Research Communications
The hypocholesterolemic activity of açaí (Euterpe oleracea Mart.) is mediated by the enhanced expression of the ATP-binding cassette, subfamily G transporters 5 and 8 and low-density lipoprotein receptor genes in the rat
Melina Oliveira de Souza, Lorena Souza e Silva, Cíntia Lopes de Brito Magalhães, Bianca Barros de Figueiredo, Daniela Caldeira Costa, Marcelo Eustáquio Silva, Maria Lúcia Pedrosa · 2012 · Nutrition Research
Bile acid‐binding activity of young persimmon (Diospyros kaki) fruit and its hypolipidemic effect in mice
Kenji Matsumoto, Shin‐ichiro Yokoyama, Nobuki Gato · 2009 · Phytotherapy Research
Cholesterol lowering and vascular protective effects of ethanolic extract of dried fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in diet-induced hypercholesterolaemic rat model
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LuXuRies of Lipid Homeostasis: The Unity of Nuclear Hormone Receptors, Transcription Regulation, and Cholesterol Sensing
Y. Zhang · 2002 · Molecular Interventions
Identification and quantitative analysis of β-sitosterol oxides in vegetable oils by capillary gas chromatography–mass spectrometry
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Overexpression of cholesterol transporter StAR increases In Vivo rates of bile acid synthesis in the rat and mouse
Shunlin Ren, Phillip B. Hylemon, Dalila Marques, Emily C. Gurley, Patricia Bodhan, Elizabeth Hall, Kaye S. Redford, Gregorio Gil, William M. Pandak · 2004 · Hepatology
Carboxymethylation of polysaccharide from Morchella angusticepes Peck enhances its cholesterol-lowering activity in rats
Yao Li, Ya Yuan, Lin Lei, Fuhua Li, Yueqiao Zhang, Jinlong Chen, Guohua Zhao, Surui Wu, Ran Yin, Jian Ming · 2017 · Carbohydrate Polymers
Increased Fecal Bile Acid Excretion in Transgenic Mice With Elevated Expression of Human Phospholipid Transfer Protein
Sabine M. Post, Rini de Crom, Rien van Haperen, Arie van Tol, Hans M. G. Princen · 2003 · Arteriosclerosis Thrombosis and Vascular Biology
Sirtuin 1 Deacetylase
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Ezetimibe decreases SREBP-1c expression in liver and reverses hepatic insulin resistance in mice fed a high-fat diet
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Oral Cholic Acid Is Efficacious and Well Tolerated in Patients With Bile Acid Synthesis and Zellweger Spectrum Disorders
James E. Heubi, Kevin E. Bove, Kenneth D.R. Setchell · 2017 · Journal of Pediatric Gastroenterology and Nutrition
Regulation of cholesterol 7 alpha-hydroxylase gene expression in Hep-G2 cells. Effect of serum, bile salts, and coordinate and noncoordinate regulation with other sterol-responsive genes
T Taniguchi, J. Chen, Allen D. Cooper · 1994 · Journal of Biological Chemistry
Transport of organic anions in the liver. An update on bile acid, fatty acid, monocarboxylate, anionic amino acid, cholephilic organic anion, and anionic drug transport
Ernst Petzinger · 1994 · Reviews of physiology, biochemistry and pharmacology
Disturbed Cholesterol Homeostasis in a Peroxisome-Deficient PEX2 Knockout Mouse Model
Werner J. Kovacs, Janis E. Shackelford, Khanichi N. Tape, Michael J. Richards, Phyllis L. Faust, Steven J. Fliesler, Skaidrite K. Krisans · 2003 · Molecular and Cellular Biology
Up-regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) in nephrotic syndrome
Nosratola D. Vaziri, Kaihui Liang · 2002 · Kidney International
Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans
Christian Victor Hulzebos, Lorraine N Renfurm, Robert Bandsma, Henkjan J. Verkade, Theo S Boer, Renze Boverhof, Hiroshi L. TANAKA, Igor Mierau, Pieter J.J. Sauer, Folkert Kuipers et al. · 2001 · Journal of Lipid Research
Abnormal bile acids in the Smith‐Lemli‐Opitz syndrome
Marvin R. Natowicz, James E. Evans · 1994 · American Journal of Medical Genetics
Repression of cholesterol 7 alpha-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes.
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Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients
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Hormonal regulation of cholesterol 7alpha-hydroxylase specific activity, mRNA levels, and transcriptional activity in vivo in the rat
William M. Pandak, Douglas M. Heuman, Kaye S. Redford, R. Todd Stravitz, John Y.L. Chiang, Phillip B. Hylemon, Zdravko R. Vlahcevic · 1997 · Journal of Lipid Research
A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands
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Attenuation of Fatty Liver and Prevention of Hypercholesterolemia by Extract of Curcuma longa through Regulating the Expression of CYP7A1, LDL‐Receptor, HO‐1, and HMG‐CoA Reductase
W. C. Yiu, Pui-Long Kwan, Cho‐Yee Wong, Tsz‐Shan Kam, Sin‐Ming Chiu, Shun‐Wan Chan, Robbie Yat‐Kan Chan · 2011 · Journal of Food Science
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Yuanyuan Zhang, Jonathan P. Jackson, Robert L. St. Claire, Kimberly Freeman, Kenneth R. Brouwer, Jeffrey E. Edwards · 2017 · Pharmacology Research & Perspectives
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Hitoshi Kurushima, Kozo Hayashi, Tetsuji Shingu, Yoshio Kuga, Harumi Ohtani, Yoshifumi Okura, Kouichi R. Tanaka, Yuji Yasunobu, Katsuhiko Nomura, Goro Kajiyama · 1995 · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
Fluorocholesterols, in contrast to hydroxycholesterols, exhibit interfacial properties similar to cholesterol
John M. Kauffman, Philip W. Westerman, Martin C. Carey · 2000 · Journal of Lipid Research
Expression of the Rat Liver Na+/Taurocholate Cotransporter Is Regulated In Vivo By Retention of Biliary Constituents But Not Their Depletion
Carsten Gartung, Stephan Schuele, Stephan F. Schlosser, James Lorenzen Boyer · 1997 · Hepatology
Characterization of Hepatic-specific Regulatory Elements in the Promoter Region of the Human Cholesterol 7α-Hydroxylase Gene
Allen D. Cooper, Jean Chen, Mary Jane Botelho-Yetkinler, Yicheng Cao, Takahiro Taniguchi, Beatriz Levy-Wilson · 1997 · Journal of Biological Chemistry
LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO-2 CELLS: A POTENTIAL ROLE FOR A NEGATIVE FARNESOID X RECEPTOR RESPONSE ELEMENT
Yuan F. Lu, Jean‐Marie Heydel, Xin Li, Stacie Moseley Bratton, Tim H. Lindblom, Anna Radominska-p · 2005 · Drug Metabolism and Disposition
Omega-3 PUFA metabolism and brain modifications during aging
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Stabilization and cytoskeletal-association of LDL receptor mRNA are mediated by distinct domains in its 3′ untranslated region
Gerald M. Wilson, Monika Z. Vasa, R G Deeley · 1998 · Journal of Lipid Research
Effect of cyclosporine on HMG-CoA reductase, cholesterol 7alpha-hydroxylase, LDL receptor, HDL receptor, VLDL receptor, and lipoprotein lipase expressions.
Nosratola D. Vaziri, Kaihui Liang, Habib Azad · 2000 · PubMed
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Bile acid transport into hepatocyte smooth endoplasmic reticulum vesicles is mediated by microsomal epoxide hydrolase, a membrane protein exhibiting two distinct topological orientations.
C Alves, Patricia J. Von Dippe, Mehran Amoui, D Levy · 1993 · Journal of Biological Chemistry
Association between serum bile acid profiles and gestational diabetes mellitus: A targeted metabolomics study
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Esterification of Oxysterols by Human Plasma Lecithin-Cholesterol Acyltransferase
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Human Δ4-3-oxosteroid 5β-reductase (AKR1D1) deficiency and steroid metabolism
Palermo, Mario, Marazzi, Maria Grazia, Hughes, Beverly A., Stewart, Paul M., Clayton, Peter T., Shackleton, Cedric H.L. · 2008 · Steroids
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The effect of taurine on cholesterol degradation in mice fed a high-cholesterol diet
Wen Chen, Keiko Matuda, Naomichi Nishimura, Hidehiko Yokogoshi · 2004 · Life Sciences
Correlation of Farnesoid X Receptor Coactivator Recruitment and Cholesterol 7α-Hydroxylase Gene Repression by Bile Acids
Kelli S. Bramlett, Sufang Yao, Thomas P. Burris · 2000 · Molecular Genetics and Metabolism
Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action
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Ewa C. S. Ellis, Scott Nauglers, Paolo Parini, Lisa-Mari Mörk, Carl Jorns, Helen Zemack, Anita Lövgren‐Sandblom, Ingemar Björkhem, Bo‐Göran Ericzon, Elizabeth M. Wilson et al. · 2013 · PLoS ONE
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Metabolism of an oxysterol, 7‐ketocholesterol, by sterol 27‐hydroxylase in hepG2 cells
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