Cited by 819Cholesterol and Lipid MetabolismDrug Transport and Resistance MechanismsSteroid Chemistry and Biochemistry

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Bile acid biosynthesis

Russell, David W., Setchell, Kenneth D. R.·1992·Biochemistry

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Abstract

To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology. The application of probes generated by these methodologies has begun to generate novel insight into bile acid metabolism, regulation, and genetics. The next several years should be equally exciting.

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Authors: Russell, D. W., & Setchell, K. D. R.
Affiliations: The University of Texas Southwestern Medical Center (US)
Cincinnati Children's Hospital Medical Center (US)
ORCID: Russell, David W.
Setchell, Kenneth D. R.
Venue: Biochemistry
Publisher: American Chemical Society (ACS)
Published: 1992-05-01
Volume: 31
Issue: 20
Pages: 4737-4749
ISSN: 0006-2960 (ISSN-L)
1520-4995
DOI: 10.1021/bi00135a001
OpenAlex: W2053916731
Cited by: 819
References: 104
Citations by year: 2026: 9 · 2025: 11 · 2024: 11 · 2023: 27 · 2022: 14 · 2021: 24 · 2020: 24 · 2019: 17 · 2018: 15 · 2017: 27 · 2016: 15 · 2015: 15 · 2014: 19 · 2013: 22 · 2012: 21
FWCI: 28.69
Type: journal article
Language: en
Open access: closed
Locations: Biochemistry (publishedVersion)
PubMed (publishedVersion)
Funders: National Heart, Lung, and Blood Institute (HL-20948, P01HL020948)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
Physical Sciences › Chemistry › Organic Chemistry › Steroid Chemistry and Biochemistry
Keywords: bile acid synthesis, bile acids, cholesterol metabolism, fat metabolism
MeSH terms: Animals, Bile Acids and Salts, Humans

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