Dependence of DNA–Protein Cross-Linking via Guanine Oxidation upon Local DNA Sequence As Studied by Restriction Endonuclease Inhibition

Genome maintenance mechanisms for preventing cancer

Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939 · see citing works

Oxidative DNA damage: mechanisms, mutation, and disease

Cooke, M. S., Evans, M. D., Dizdaroglu, M., & Lunec, J. (2003) · The FASEB Journal · doi:10.1096/fj.02-0752rev · Cited by 3,245 · see citing works

Role of oxygen radicals in DNA damage and cancer incidence

Valko, M., Izakovic, M., Mazur, M., Rhodes, C. J., & Telser, J. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000049134.69131.89 · Cited by 1,820 · see citing works

Oxidative Nucleobase Modifications Leading to Strand Scission

Burrows, C. J., & Muller, J. G. (1998) · Chemical Reviews · doi:10.1021/cr960421s · Cited by 1,736 · see citing works

Cellular Defenses against Superoxide and Hydrogen Peroxide

Imlay, J. A. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061606.161055 · Cited by 1,563 · see citing works

How Easily Oxidizable Is DNA? One-Electron Reduction Potentials of Adenosine and Guanosine Radicals in Aqueous Solution

Steenken, S., & Jovanovic, S. V. (1997) · Journal of the American Chemical Society · doi:10.1021/ja962255b · Cited by 1,450 · see citing works

The multifaceted mismatch-repair system

Jiricny, J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1907 · Cited by 1,375 · see citing works

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

Storz, G., Tartaglia, L. A., & Ames, B. N. (1990) · Science · doi:10.1126/science.2183352 · Cited by 864 · see citing works

Oxidative DNA damage through long-range electron transfer

Hall, D. B., Holmlin, R. E., & Barton, J. K. (1996) · Nature · doi:10.1038/382731a0 · Cited by 825 · see citing works

Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells

Barnes, D. E., & Lindahl, T. (2004) · Annual Review of Genetics · doi:10.1146/annurev.genet.38.072902.092448 · Cited by 753 · see citing works

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

Wood, M. L., Dizdaroğlu, M., Gajewski, E., & Essigmann, J. M. (1990) · Biochemistry · doi:10.1021/bi00482a011 · Cited by 684 · see citing works

Theoretical Studies of GG-Specific Photocleavage of DNA via Electron Transfer: Significant Lowering of Ionization Potential and 5‘-Localization of HOMO of Stacked GG Bases in B-Form DNA

Sugiyama, H., & Saito, I. (1996) · Journal of the American Chemical Society · doi:10.1021/ja9609821 · Cited by 629 · see citing works

DNA mismatch repair: Molecular mechanism, cancer, and ageing

Hsieh, P., & Yamane, K. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.02.012 · Cited by 463 · see citing works

Photoinduced DNA Cleavage via Electron Transfer: Demonstration That Guanine Residues Located 5' to Guanine Are the Most Electron-Donating Sites

Saito, I., Takayama, M., Sugiyama, H., Nakatani, K., Tsuchida, A., & Yamamoto, M. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00128a050 · Cited by 418 · see citing works

Structure and acid-base properties of one-electron-oxidized deoxyguanosine, guanosine, and 1-methylguanosine

Candeias, L. P., & Steenken, S. (1989) · Journal of the American Chemical Society · doi:10.1021/ja00185a046 · Cited by 396 · see citing works

Chemistry and Biology of DNA Repair

Schärer, O. D. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200523 · Cited by 381 · see citing works

Synthesis and study of a mixed-ligand ruthenium( II ) complex in its ground and excited states: bis(2,2′-bipyridine)(dipyrido[3,2-a : 2′,3′-c]phenazine-N 4 N 5 )ruthenium( II )

Amouyal, E., Homsi, A., Chambron, J., & Sauvage, J. (1990) · Journal of the Chemical Society Dalton Transactions · doi:10.1039/dt9900001841 · Cited by 360 · see citing works

DNA?protein crosslinks: their induction, repair, and biological consequences

BARKER, S., Weinfeld, M., & MURRAY, D. (2005) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2004.11.003 · Cited by 315 · see citing works

Oxidation of Guanine in DNA by Ru(phen)2(dppz)3+ Using the Flash-Quench Technique

Stemp, E. D. A., Arkin, M. R., & Barton, J. K. (1997) · Journal of the American Chemical Society · doi:10.1021/ja963606p · Cited by 212 · see citing works

Characterization of Hydantoin Products from One-Electron Oxidation of 8-Oxo-7,8-dihydroguanosine in a Nucleoside Model

Luo, W., Muller, J. G., Rachlin, E. M., & Burrows, C. J. (2001) · Chemical Research in Toxicology · doi:10.1021/tx010072j · Cited by 200 · see citing works

Ru(phen) 2 dppz 2+ Luminescence: Dependence on DNA Sequences and Groove-Binding Agents

Holmlin, R. E., Stemp, E. D. A., & Barton, J. K. (1998) · Inorganic Chemistry · doi:10.1021/ic970869r · Cited by 196 · see citing works

Long-range oxidation of guanine by Ru(III) in duplex DNA

Arkin, M. R., Stemp, E. D. A., Pulver, S. C., & Barton, J. K. (1997) · Chemistry & Biology · doi:10.1016/s1074-5521(97)90129-0 · Cited by 188 · see citing works

Characterization of Lysine−Guanine Cross-Links upon One-Electron Oxidation of a Guanine-Containing Oligonucleotide in the Presence of a Trilysine Peptide

Perrier, S., Hau, J., Gasparutto, D., Cadet, J., Favier, A., & Ravanat, J.-L. (2006) · Journal of the American Chemical Society · doi:10.1021/ja057656i · Cited by 141 · see citing works

High-driving-force electron transfer in metalloproteins: intramolecular oxidation of ferrocytochrome c by Ru(2,2'-bpy)2(im)(his-33)3+

Chang, I. J., Gray, H. B., & Winkler, J. R. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00018a064 · Cited by 135 · see citing works

Photochemistry of Complex Ions. I. Some Photochemical Reactions of Aqueous PtBr6-2, Mo(CN)8-4 and Various Co(III) and Cr(III) Complex Ions

Adamson, A. W., & Sporer, A. H. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01548a016 · Cited by 131 · see citing works

Oxidative Charge Transport through DNA in Nucleosome Core Particles

Núñez, M. E., Noyes, K. T., & Barton, J. K. (2002) · Chemistry & Biology · doi:10.1016/s1074-5521(02)00121-7 · Cited by 106 · see citing works

Chemical nature of DNA-protein cross-links produced in mammalian chromatin by hydrogen peroxide in the presence of iron or copper ions

Nackerdien, Z. E., Rao, G., Cacciuttolo, M. A., Gajewski, E., & Dizdaroğlu, M. (1991) · Biochemistry · doi:10.1021/bi00234a006 · Cited by 100 · see citing works

Distinctive sequence patterns in metazoan and yeast nucleosomes: Implications for linker histone binding to AT-rich and methylated DNA

Cui, F., & Zhurkin, V. B. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp113 · Cited by 67 · see citing works

Photooxidation of Tryptophan: O2(1Δg) versus Electron‐Transfer Pathway

Wessels, J. M., Foote, C. S., Ford, W. E., & Rodgers, M. A. J. (1997) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1997.tb01883.x · Cited by 63 · see citing works

DNA−Protein Cross-Linking from Oxidation of Guanine via the Flash−Quench Technique

Nguyen, K. L., Steryo, M., Kurbanyan, K., Nowitzki, K. M., Butterfield, S. M., Ward, S. R., & Stemp, E. D. A. (2000) · Journal of the American Chemical Society · doi:10.1021/ja993502p · Cited by 59 · see citing works

Base-selective oxidation and cleavage of DNA by photochemical cosensitized electron transfer

Dunn, D. A., Lin, V. H., & Kochevar, I. E. (1992) · Biochemistry · doi:10.1021/bi00161a048 · Cited by 58 · see citing works

DNA−Protein Cross-Linking via Guanine Oxidation:  Dependence upon Protein and Photosensitizer

Kurbanyan, K., Nguyen, K. L., To, P., Rivas, E. V., Lueras, A. M. K., Kosinski, C., Steryo, M., González, A., Mah, D. A., & Stemp, E. D. A. (2003) · Biochemistry · doi:10.1021/bi020713p · Cited by 53 · see citing works

Fluorescence Recovery Assay for the Detection of Protein−DNA Binding

Xu, X., Zhao, Z. Z., Qin, L., Wei, W., Levine, J. E., & Mirkin, C. A. (2008) · Analytical Chemistry · doi:10.1021/ac8007016 · Cited by 52 · see citing works

DNA-Bound Peptide Radicals Generated through DNA-Mediated Electron Transport

Wagenknecht, H., Stemp, E. D. A., & Barton, J. K. (2000) · Biochemistry · doi:10.1021/bi992897m · Cited by 52 · see citing works

The preferential binding of histone H1 to DNA scaffold-associated regions is determined by its C-terminal domain

Roque, A. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh945 · Cited by 45 · see citing works

Kinetics of ammonia detachment from reduced cobalt(III) complexes based on conductometric pulse radiolysis

Simic, M., & Lilie, J. (1974) · Journal of the American Chemical Society · doi:10.1021/ja00808a068 · Cited by 45 · see citing works

DNA Cross-Linking with Metallointercalator−Peptide Conjugates

Copeland, K. D., Lueras, A. M. K., Stemp, E. D. A., & Barton, J. K. (2002) · Biochemistry · doi:10.1021/bi020407b · Cited by 43 · see citing works

ChemInform Abstract: KINETICS OF AMMONIA DETACHMENT FROM REDUCED COBALT(III) COMPLEXES BASED ON CONDUCTOMETRIC PULSE RADIOLYSIS

Simic, M., & Lilie, J. (1974) · ChemInform · doi:10.1002/chin.197412425 · Cited by 42 · see citing works

Type I Benzophenone-Mediated Nucleophilic Reaction of 5'-Amino-2',5'-dideoxyguanosine. A Model System for the Investigation of Photosensitized Formation of DNA-Protein Cross-Links

Morin, B., & Cadet, J. (1995) · Chemical Research in Toxicology · doi:10.1021/tx00047a020 · Cited by 40 · see citing works

Stable DNA−Protein Cross-Links Are Products of DNA Charge Transport in a Nucleosome Core Particle

Bjorklund, C. C., & Davis, W. B. (2007) · Biochemistry · doi:10.1021/bi700475b · Cited by 40 · see citing works

Photochemistry of complex ions. XII. Photochemistry of cobalt(III) acidoammines

Pribush, R. A., POON, C. ‐., Bruce, C. M., & Adamson, A. W. (1974) · Journal of the American Chemical Society · doi:10.1021/ja00817a001 · Cited by 38 · see citing works

BENZOPHENONE PHOTOSENSITIZATION OF 2′‐DEOXYGUANOSINE: CHARACTERIZATION OF THE 2R AND 2s DIASTEREOISOMERS OF 1‐(2‐DEOXY‐β‐D‐erythoW‐PENTOFURANOSYL)‐2‐METHOXY‐4,5‐IMIDAZOLIDINEDIONE. A MODEL SYSTEM FOR THE INVESTIGATION OF PHOTOSENSITIZED FORMATION OF DNA‐PROTEIN CROSSLINKS

Morin, B., & Cadet, J. (1994) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1994.tb05074.x · Cited by 33 · see citing works

DNA Oxidation by Charge Transport in Mitochondria

Merino, E. J., & Barton, J. K. (2008) · Biochemistry · doi:10.1021/bi701775s · Cited by 31 · see citing works

Radiation-induced damage to DNA: mechanistic aspects and measurement of base lesions

Cadet, J., Douki, T., Gasparutto, D., Gromova, M., Pouget, J., Ravanat, J., Romieu, A., & Sauvaigo, S. (1999) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/s0168-583x(99)00117-2 · Cited by 29 · see citing works

Copper generated reactive oxygen leads to formation of lysine–DNA adducts

Solivio, M. J., Joy, T. J., Sallans, L., & Merino, E. J. (2010) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2010.05.006 · Cited by 21 · see citing works

Assay of protein kinase C with an N-bromosuccinimide-cleavage fragment of histone H1

Glynn, B. P., Colliton, J. W., McDermott, J. C., & Witters, L. A. (1985) · Biochemical Journal · doi:10.1042/bj2310489 · Cited by 17 · see citing works

Histone H1 Interacts Specifically with Certain Regions of the Mouse α-Globin Gene

Yaneva, J. N., & Zlatanova, J. S. (1992) · DNA and Cell Biology · doi:10.1089/dna.1992.11.91 · Cited by 16 · see citing works

DNA sequence specific interactions of histone H1

Zlatanova, J. S., & Yaneva, J. N. (1991) · Molecular Biology Reports · doi:10.1007/bf00369901 · Cited by 14 · see citing works

Restriction Enzyme Mapping of Carcinogen Binding Regions on pBR322

Mallamaci, M. A., Reed, D. P., & Winkle, S. A. (1992) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.1992.10508631 · Cited by 4 · see citing works

Locating Binding Sites for the Carcinogen N-Acetoxy-N-Acetyl-2-Aminofluorene Using Restriction Enzyme Inhibition Assays

Mallamaci, M. A., Bascoy, M. L., Brown, J. S., Combates, N. J., & Winkle, S. A. (1992) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.1992.10508632 · Cited by 4 · see citing works

Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions^†

Cadet, J., Mouret, S., Ravanat, J., & Douki, T. (2012) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.2012.01200.x · Cited by 300 · see citing works

Oxidatively generated complex DNA damage: Tandem and clustered lesions

Cadet, J., Ravanat, J.-L., TavernaPorro, M., Menoni, H., & Angelov, D. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.04.005 · Cited by 233 · see citing works

Photosensitization Reactions of Biomolecules: Definition, Targets and Mechanisms

Baptista, M. S., Cadet, J., Greer, A., & Thomas, A. H. (2021) · Photochemistry and Photobiology · doi:10.1111/php.13470 · Cited by 205 · see citing works

Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: similarities and differences

Cadet, J., & Wagner, J. R. (2014) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2014.05.001 · Cited by 169 · see citing works

One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA

Cadet, J., Wagner, J. R., Shafirovich, V., & Geacintov, N. E. (2013) · International Journal of Radiation Biology · doi:10.3109/09553002.2013.877176 · Cited by 152 · see citing works

From cultivation to cancer: formation of N -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications

Stanfill, S. B., Hecht, S. S., Joerger, A. C., González, P. J., Maia, L. B., Rivas, M. G., Moura, J. J. G., Gupta, A., Brun, N. E. L., Crack, J. C., et al. (2023) · Critical Reviews in Toxicology · doi:10.1080/10408444.2023.2264327 · Cited by 44 · see citing works

Guanine holes are prominent targets for mutation in cancer and inherited disease

Bacolla, A., Temiz, N. A., Yi, M., Ivanic, J., Cer, R. Z., Donohue, D. E., Ball, E. V., Mudunuri, U. S., Wang, G., Jain, A., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003816 · Cited by 40 · see citing works

Modulation of Cell Death in Age-Related Diseases

Tezil, T., & Başağa, H. (2014) · Current Pharmaceutical Design · doi:10.2174/13816128113196660702 · Cited by 21 · see citing works

AID and Reactive Oxygen Species Can Induce DNA Breaks within Human Chromosomal Translocation Fragile Zones

Pannunzio, N. R., & Lieber, M. R. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.11.011 · Cited by 20 · see citing works

Capturing Protein–Nucleic Acid Interactions by High‐Intensity Laser‐Induced Covalent Cross‐Linking †

Angelov, D., Boopathi, R., Lone, I. N., Menoni, H., Dimitrov, S. I., & Cadet, J. (2022) · Photochemistry and Photobiology · doi:10.1111/php.13699 · Cited by 14 · see citing works

DNA–Histone Cross-Link Formation via Hole Trapping in Nucleosome Core Particles

Wen, T., Kermarrec, M., Dumont, E. E., Gillet, N., & Greenberg, M. M. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c08135 · Cited by 8 · see citing works

Glutathione Directly Intercepts DNA Radicals To Inhibit Oxidative DNA–Protein Cross-Linking Induced by the One-Electron Oxidation of Guanine

Safaeipour, M., Jauregui, J., Castillo, S., Bekarian, M., Esparza, D., Sanchez, M., & Stemp, E. D. A. (2019) · Biochemistry · doi:10.1021/acs.biochem.9b00697 · Cited by 8 · see citing works

Mutual effects between aromatic amino acids and guanosine upon vitamin B2 photosensitization in the presence of visible light

Montaña, M. P., Ferrari, G., Gatica, E. A., Natera, J., Massad, W. A., & Garcı́a, N. A. (2013) · Canadian Journal of Chemistry · doi:10.1139/cjc-2012-0251 · Cited by 4 · see citing works

Enantioselectively Generating the More Mutagenic Imidazolone Diz by the Chiral DNA Intercalating and “Light-Switching” Ru(Ii) Polypyridyl Complex Via a Novel Flash-Quench Method

Shao, J., Chen, J., Ke, R.-X., Huang, C., Tang, T.-S., Liu, Z., Mao, J.-Y., Huang, R., & Zhu, B. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.09.045 · Cited by 3 · see citing works

Crosslinking pathways, dynamics, and kinetics between guanosine and lysine following one- versus two-electron oxidation of guanosine

Moe, M. M., Benny, J., Lee, V., Tsai, M., & Liu, J. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf071 · Cited by 1 · see citing works

Formation of DNA Lesions, its Prevention and Repair

Jena, N. R., Agnihotri, N. P., & Mishra, P. C. (2014) · Challenges and advances in computational chemistry and physics · doi:10.1007/978-94-017-9257-8_3

Enantioselectively Generating the More Mutagenic Imidazolone Diz by the Chiral DNA Intercalating and “Light-Switching” Ru(Ii) Polypyridyl Complex Via a Novel Flash-Quench MethodPreprint

Shao, J., Chen, J., Ke, R.-X., Huang, C., Tang, T.-S., Liu, Z., Mao, J.-Y., Huang, R., & Zhu, B. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4896845

Can DNA‐Protein Crosslinking Be Induced by One‐Electron Oxidation of 8‐Oxoguanosine? A Model Study of 9‐Methyl‐8‐Oxoguanine Radical Cation With Methylamine

Zhou, W., Feng, L., Moe, M. M., Ceballos, J., Tsai, M., & Liu, J. (2026) · Chemistry - A European Journal · doi:10.1002/chem.202503540

Dependence of DNA‐protein cross‐linking via guanine oxidation upon local DNA sequence

Perez, Z. A., & Stemp, E. D. A. (2012) · The FASEB Journal · doi:10.1096/fasebj.26.1_supplement.740.7

DNA−Protein Cross-Linking via Guanine Oxidation:  Dependence upon Protein and Photosensitizer

Kurbanyan, K., Nguyen, K. L., To, P., Rivas, E. V., Lueras, A. M. K., Kosinski, C., Steryo, M., González, A., Mah, D. A., & Stemp, E. D. A. (2003) · Biochemistry · doi:10.1021/bi020713p · Cited by 53 · see citing works

Abstract 2412 "Design of a Model System for Studying Long Range Oxidation in DNA"

Espinosa, T., Shinzato, J., Stemp, E. D. A., & Lee, P. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.106052

Role of base pairing partner on DNA‐protein crosslinking from guanine oxidation

Perez, Z. A., Madison, A., & Stemp, E. D. A. (2010) · The FASEB Journal · doi:10.1096/fasebj.24.1_supplement.874.2

Biologically Relevant Oxidants Cause Bound Proteins To Readily Oxidatively Cross-Link at Guanine

Solivio, M. J., Nemera, D. B., Sallans, L., & Merino, E. J. (2012) · Chemical Research in Toxicology · doi:10.1021/tx200376e · Cited by 20 · see citing works