The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Caprolactonic Poloxamer Analog: PEG-PCL-PEG
Abstract
The aqueous solution of poly(ethylene glycol)-poly(caprolactone)-poly(ethylene glycol) (PEG-PCL-PEG) triblock copolymers (> 15. wt. %) undergoing "clear sol-gel-turbid sol" transition as the temperature increases from 20 to 60 degrees C has been developed. Light scattering and 13C NMR study suggested that the transition mechanisms are the micellar aggregation for the clear sol to gel transition (lower transition), whereas the increase in PCL molecular motion for gel to turbid sol transition (upper transition). In contrast to the previous thermogelling biodegradable polymers with a sticky paste morphology, the powder form of the PEG-PCL-PEG triblock copolymers makes it easy to handle and allows fast dissolution in water. Therefore, the lyophilization into a powder form followed by facile reconstitution was possible. This system is believed to be promising for drug delivery, cell therapy, and tissue engineering.
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Cites
Novel injectable neutral solutions of chitosan form biodegradable gels in situ
Chenite, A., Chaput, C., Wang, D., Combes, C., Buschmann, M. D., Hoemann, C. D., Leroux, J. C., Atkinson, B. L., Binette, F., & Selmani, A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00116-2 · Cited by 1,406
Jeong, B., Bae, Y. H., & Kim, S. W. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00194-7 · Cited by 635
Self-citationThermoreversible Gelation of PEG−PLGA−PEG Triblock Copolymer Aqueous Solutions
Jeong, B., Bae, Y. H., & Kim, S. W. (1999) · Macromolecules · doi:10.1021/ma9908999 · Cited by 619
Self-citationBooth, C., & Attwood, D. (2000) · Macromolecular Rapid Communications · doi:10.1002/1521-3927(20000601)21:9<501::aid-marc501>3.0.co;2-r · Cited by 416
In situ forming parenteral drug delivery systems: an overview
Packhaeuser, C. B., Schnieders, J., Oster, C. G., & Kissel, T. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.03.003 · Cited by 413
Stile, R. A., Burghardt, W. R., & Healy, K. E. (1999) · Macromolecules · doi:10.1021/ma990130w · Cited by 363
Sol−Gel Transition Temperature of PLGA-g-PEG Aqueous Solutions
Chung, Y.-M., Simmons, K. L., Gutowska, A., & Jeong, B. (2002) · Biomacromolecules · doi:10.1021/bm0156431 · Cited by 194
Self-citationJeong, B., Lee, K. M., Gutowska, A., & An, Y. H. (2002) · Biomacromolecules · doi:10.1021/bm025536m · Cited by 152
Self-citationMicrofabrication technology for polycaprolactone, a biodegradable polymer
Armani, D. K., & Liu, C. (2000) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/10/1/311 · Cited by 132
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Cited by
Block copolymer micelles: preparation, characterization and application in drug delivery
Gaucher, G., Dufresne, M.-H., Sant, V. P., Kang, N., Maysinger, D., & Leroux, J.-C. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.09.034 · Cited by 1,498
Hydrogels in a historical perspective: From simple networks to smart materials
Buwalda, S. J., Boere, K. W. M., Dijkstra, P. J., Feijen, J., Vermonden, T., & Hennink, W. E. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.03.052 · Cited by 994
In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery
He, C., Kim, S. W., & Lee, D. S. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.01.005 · Cited by 867
Self-citationInjectable Biodegradable Hydrogels
Nguyen, M. K., & Lee, D. S. (2010) · Macromolecular Bioscience · doi:10.1002/mabi.200900402 · Cited by 481
PEG-based thermosensitive and biodegradable hydrogels
Shi, J., Yu, L., & Ding, J. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.04.009 · Cited by 341
Metadata
- Authors
- Hwang, M. J., Suh, J. M., Bae, Y. H., Kim, S. W., & Jeong, B.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-01-13
- Volume
- 6
- Issue
- 2
- Pages
- 885-890
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2089530114
- Cited by
- 262
- References
- 12
- FWCI
- 6.26
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
