The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Dendrimers: Novel Polymeric Nanoarchitectures for Solubility Enhancement
Abstract
Poor solubility and hydrophobicity of drugs/bioactives limit their possible applications in drug delivery and formulation development. Apart from conventional methods of solubility enhancement, there are some novel methods which can be used in solubilization. Dendrimers represent a novel type of polymeric material that has generated much interest in many diverse areas due to their unique structure and properties. Dendrimer-mediated solubility enhancement mainly depends on factors such as generation size, dendrimer concentration, pH, core, temperature, and terminal functionality. Added advantage in solubilization can be achieved considering these factors. Available literature suggests that ionic interaction, hydrogen bonding, and hydrophobic interactions are the possible mechanisms by which a dendrimer exerts its solubilizing property. This review presents various mechanisms and reports relating to solubility enhancement using dendrimers. Also, micellar behavior and future possibilities in relation to solubilization via dendrimers are included.
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Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00129-0 · Cited by 18,139
A New Class of Polymers: Starburst-Dendritic Macromolecules
Tomalia, D. A., Baker, H., Dewald, J., Hall, M., Kallos, G., Martin, S., Roeck, J., Ryder, J., & Smith, P. (1985) · Polymer Journal · doi:10.1295/polymj.17.117 · Cited by 3,904
Biodegradable Long-Circulating Polymeric Nanospheres
Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V., Torchilin, V., & Langer, R. (1994) · Science · doi:10.1126/science.8128245 · Cited by 2,920
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
Esfand, R., & Tomalia, D. A. (2001) · Drug Discovery Today · doi:10.1016/s1359-6446(01)01757-3 · Cited by 1,562
Kukowska-Latallo, J. F., Bielinska, A. U., Johnson, J., Spindler, R., Tomalia, D. A., & Baker, J. R. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.10.4897 · Cited by 1,006
Dendrimer‐based metal chelates: A new class of magnetic resonance imaging contrast agents
Wiener, E., Brechbiel, M. W., Brothers, H., Magin, R. L., Gansow, O. A., Tomalia, D. A., & Lauterbur, P. C. (1994) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910310102 · Cited by 718
Kojima, C., Kono, K., Maruyama, K., & Takagishi, T. (2000) · Bioconjugate Chemistry · doi:10.1021/bc0000583 · Cited by 663
Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless
Sehgal, A., Price, J. L., Man, B., & Young, M. W. (1994) · Science · doi:10.1126/science.8128246 · Cited by 651
Dendritic polymer macromolecular carriers for drug delivery
Patri, A. K., Majoros, I. J., & Baker, J. R. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00347-2 · Cited by 595
A PEGylated dendritic nanoparticulate carrier of fluorouracil
Bhadra, D., Bhadra, S., Jain, S., & Jain, N. K. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00132-7 · Cited by 544
Self-citation
Cited by
Dendrimers Derived from 1 → 3 Branching Motifs
Newkome, G. R., & Shreiner, C. (2010) · Chemical Reviews · doi:10.1021/cr900341m · Cited by 347
New frontiers in nanotechnology for cancer treatment
Alexis, F., Rhee, J.-W., Richie, J. P., Radovic-Moreno, A. F., Langer, R., & Farokhzad, O. C. (2008) · Urologic Oncology: Seminars and Original Investigations · doi:10.1016/j.urolonc.2007.03.017 · Cited by 347
Recent advances of discrete coordination complexes and coordination polymers in drug delivery
Ma, Z., & Moulton, B. (2011) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2011.01.031 · Cited by 310
Targeting cancer cells with biotin–dendrimer conjugates
Yang, W., Cheng, Y., Xu, T., Wang, X., & Wen, L.-P. (2009) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2008.04.021 · Cited by 290
Kaminskas, L. M., Kelly, B. D., McLeod, V. M., Sberna, G., Owen, D. J., Boyd, B. J., & Porter, C. J. H. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.02.005 · Cited by 137
Metadata
- Authors
- Gupta, U., Agashe, H. B., Asthana, A., & Jain, N. K.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-02-15
- Volume
- 7
- Issue
- 3
- Pages
- 649-658
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2082904634
- Cited by
- 375
- References
- 33
- FWCI
- 25.30
- Type
- journal article
- Language
- en
- Open access
- closed
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