The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Nanoparticle‐Mediated Drug Delivery and Gene Therapy
Abstract
Biomedical application of nanotechnology is a rapidly developing area that raises new prospect in the improvement of diagnosis and treatment of human diseases. The ability to incorporate drugs or genes into a functionalized nanoparticle demonstrates a new era in pharmacotherapy for delivering drugs or genes selectively to tissues or cells. It is envisioned that the transfer of nanoengineering capability into disease therapy will provide constant and concentrated drug delivery to targeted tissues, minimizing systemic side effects and toxicity. We have in this article highlighted the recent state of the art in nanomedicine, focusing particularly on the achievement of nanotechnology in nanoscale drug and gene delivery in vitro and in vivo. In addition, a specific emphasis has been placed on the use of nanotechnology to improve controlled drug release and sustainable drug delivery in solid tumors and on new drug therapies for age‐related neurodegenerative disorders.
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Cites
Toxic potential of materials at the nanolevel
Nel, A., Xia, T., Mädler, L., & Li, N. (2006) · Science · doi:10.1126/science.1114397 · Cited by 9,324
Drug Delivery Systems: Entering the Mainstream
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Formulation of functionalized PLGA-PEG Nanoparticles for in vivo targeted drug delivery
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Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems
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Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation
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Gene targeting in vivo by adeno‐associated virus vectors
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Cited by
Nanomaterials for Theranostics: Recent Advances and Future Challenges
Lim, E.-K., Kim, T., Paik, S., Haam, S., Huh, Y.-M., & Lee, K. (2015) · Chemical Reviews · doi:10.1021/cr300213b · Cited by 1,233
PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect
Acharya, S., & Sahoo, S. K. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.10.008 · Cited by 1,112
Biocompatible Quantum Dots for Biological Applications
Rosenthal, S. J., Chang, J. C., Kovtun, O., McBride, J. R., & Tomlinson, I. D. (2011) · Chemistry & Biology · doi:10.1016/j.chembiol.2010.11.013 · Cited by 532
Nanomaterials for Neural Interfaces
Kotov, N. A., Winter, J. O., Clements, I. P., Jan, E., Timko, B. P., Campidelli, S., Pathak, S., Mazzatenta, A., Lieber, C. M., Prato, M., et al. (2009) · Advanced Materials · doi:10.1002/adma.200801984 · Cited by 504
Quantum dots as a platform for nanoparticle drug delivery vehicle design
Probst, C. E., Zrazhevskiy, P., Bagalkot, V., & Gao, X. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.036 · Cited by 466
Metadata
- Authors
- Jin, S., & Ye, K.
- Venue
- Biotechnology Progress
- Publisher
- Wiley
- Published
- 2007-01
- Volume
- 23
- Issue
- 1
- Pages
- 32-41
- ISSN
- 1520-6033 (ISSN-L)
- 8756-7938
- OpenAlex
- W2068303118
- Cited by
- 283
- References
- 7
- FWCI
- 8.55
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.