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Cited by 536

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Bright Building Blocks for Chemical Biology

Open access
Lavis, Luke D., Raines, Ronald T.·2014·ACS Chemical Biology

Abstract

Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology. As we noted in a previous review (Lavis, L. D.; Raines, R. T. ACS Chem. Biol. 2008, 3, 142-155), the extant collection of fluorescent probes is built on a modest set of "core" scaffolds that evolved during a century of academic and industrial research. Here, we survey traditional and modern synthetic routes to small-molecule fluorophores and highlight recent biological insights attained with customized fluorescent probes. Our intent is to inspire the design and creation of new high-precision tools that empower chemical biologists.

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Metadata

Authors
Lavis, L. D., & Raines, R. T.
Venue
ACS Chemical Biology
Published
2014-03-20
Volume
9
Issue
4
Pages
855-866
ISSN
  • 1554-8929 (ISSN-L)
  • 1554-8937
OpenAlex
W2009803588
Cited by
536
References
1
FWCI
18.77
Type
journal article
Language
en
Open access
hybrid

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