The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery
Abstract
Nanosized mesoporous silica particles with high colloidal stability attract growing attention as drug delivery systems for targeted cancer treatment and as bioimaging devices. This Perspective describes recent breakthroughs in mesoporous silica nanoparticle design to demonstrate their high potential as multifunctional drug delivery nanocarriers. These types of nanoparticles can feature a well-defined and tunable porosity at the nanometer scale, high loading capacity, and multiple functionality for targeting and entering different types of cells. We focus on the requirements for an efficient stimuli-responsive and thus controllable release of cargo into cancer cells and discuss design principles for smart and autonomous nanocarrier systems. Mesoporous silica nanoparticles are viewed as a promising and flexible platform for numerous biomedical applications.
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Cites
Nanocarriers as an emerging platform for cancer therapy
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Multidrug resistance in cancer: role of ATP–dependent transporters
Gottesman, M. M., Fojo, T., & Bates, S. E. (2002) · Nature Reviews Cancer · doi:10.1038/nrc706 · Cited by 5,536
Cancer nanotechnology: opportunities and challenges
Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558
Mesoporous silica nanoparticles for drug delivery and biosensing applications
Slowing, I. I., Trewyn, B. G., Giri, S., & Lin, V. S. ‐. (2007) · Advanced Functional Materials · doi:10.1002/adfm.200601191 · Cited by 1,699
Endosomal escape pathways for delivery of biologicals
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Cited by
Mesoporous Silica Nanoparticles for Drug Delivery
Manzano, M., & Vallet‐Regí, M. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201902634 · Cited by 939
Croissant, J. G., Fatieiev, Y., Almalik, A., & Khashab, N. M. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700831 · Cited by 594
Mesoporous Silica Nanoparticles for Drug Delivery: Current Insights
Vallet-Regí, M., Colilla, M., Izquierdo-Barba, I., & Manzano, M. (2017) · Molecules · doi:10.3390/molecules23010047 · Cited by 538
Qu, J., Zhao, X., Ma, P. X., & Guo, B. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.03.018 · Cited by 468
Gao, H., Wang, J., Chen, X., Wang, G., Huang, X., Li, A., & Dong, W. (2018) · Nano Energy · doi:10.1016/j.nanoen.2018.09.007 · Cited by 391
Metadata
- Authors
- Argyo, C., Weiss, V., Bräuchle, C., & Bein, T.
- Venue
- Chemistry of Materials
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-11-08
- Volume
- 26
- Issue
- 1
- Pages
- 435-451
- ISSN
- 0897-4756 (ISSN-L)
- 1520-5002
- OpenAlex
- W2333220160
- Cited by
- 903
- References
- 6
- FWCI
- 29.71
- Type
- journal article
- Language
- en
- Open access
- closed
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