The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Design of Folded Peptides
Abstract
The construction of complex protein folds relies on the precise conversion of a linear polypeptide chain into a compact 3-dimensional structure. The interplay of forces that link sequence and folding is intricate and yet to be firmly elucidated. Examination of protein 3-dimensional structures suggests that complex tertiary folds and quaternary associations can be deconstructed into a limited number of secondary structural elements, such as strands, helices, and turns, which are assembled using loosely structured loops (Figure 1). The stability of a specific fold is determined by tertiary interactions between residues which are distant in sequence. De novo design of existing or novel protein folds demands a thorough understanding of the rules that underlie protein structure and stability.\n
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Chou, P. Y., & Fasman, G. D. (1974) · Biochemistry · doi:10.1021/bi00699a001 · Cited by 2,172
A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants
Harbury, P. B., Zhang, T., Kim, P. S., & Alber, T. (1993) · Science · doi:10.1126/science.8248779 · Cited by 1,490
Schafmeister, C. E., Po, J., & Verdine, G. L. (2000) · Journal of the American Chemical Society · doi:10.1021/ja000563a · Cited by 1,037
Elucidating the folding problem of helical peptides using empirical parameters
Muñoz, V., & Serrano, L. (1994) · Nature Structural & Molecular Biology · doi:10.1038/nsb0694-399 · Cited by 721
Crystal structure of an isoleucine-zipper trimer
Harbury, P. B., Kim, P. S., & Alber, T. (1994) · Nature · doi:10.1038/371080a0 · Cited by 472
General approach to the synthesis of short .alpha.-helical peptides
Jackson, D. Y., King, D. S., Chmielewski, J., Singh, S., & Schultz, P. G. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00024a067 · Cited by 313
Chorev, M., Roubini, E., McKee, R. L., Gibbons, S. W., Goldman, M. E., Caulfield, M. P., & Rosenblatt, M. (1991) · Biochemistry · doi:10.1021/bi00238a022 · Cited by 107
Cited by
Benner, S. A., & Sismour, A. M. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1637 · Cited by 834
Vasudev, P. G., Chatterjee, S., Shamala, N., & Balaram, P. (2011) · Chemical Reviews · doi:10.1021/cr100100x · Cited by 329
Self-citationThe Road from Host-Defense Peptides to a New Generation of Antimicrobial Drugs
Boto, A., Pérez de la Lastra, J., & González, C. (2018) · Molecules · doi:10.3390/molecules23020311 · Cited by 136
Villard, J., Kılıç, M., & Rothlisberger, U. (2023) · Journal of Chemical Theory and Computation · doi:10.1021/acs.jctc.2c01078 · Cited by 19
Metadata
- Authors
- Venkatraman, J., Shankaramma, S. C., & Balaram, P.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-09-15
- Volume
- 101
- Issue
- 10
- Pages
- 3131-3152
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2155921797
- Cited by
- 689
- References
- 7
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- closed
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