Are Alkyne Reductions Chemo-, Regio-, and Stereoselective Enough To Provide Pure (Z)-Olefins in Polyfunctionalized Bioactive Molecules?

Metal‐Catalyzed Cross‐Coupling Reactions

(2004) · Wiley eBooks · doi:10.1002/9783527619535 · Cited by 4,267

The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

Maryanoff, B. E., & Reitz, A. B. (1989) · Chemical Reviews · doi:10.1021/cr00094a007 · Cited by 2,605

March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure

Smith, M. B., & March, J. (2006) · doi:10.1002/0470084960 · Cited by 2,089

The Endocannabinoid System as an Emerging Target of Pharmacotherapy

Pacher, P., Bátkai, S., & Kunos, G. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.2 · Cited by 2,077

Handbook of Metathesis: Catalyst Development

(2003) · Wiley eBooks · doi:10.1002/9783527619481 · Cited by 1,671

The Utility of Phosphonate Carbanions in Olefin Synthesis

Wadsworth, W. S., & Emmons, W. D. (1961) · Journal of the American Chemical Society · doi:10.1021/ja01468a042 · Cited by 1,401

Ein neuer Katalysator für selektive Hydrierungen

Lindlar, H. (1952) · Helvetica Chimica Acta · doi:10.1002/hlca.19520350205 · Cited by 1,168

Sodium Borohydride, Its Hydrolysis and its Use as a Reducing Agent and in the Generation of Hydrogen1

Schlesinger, H. I., Brown, H. C., Finholt, A. E., Gilbreath, J. R., Hoekstra, H. R., & Hyde, E. K. (1953) · Journal of the American Chemical Society · doi:10.1021/ja01097a057 · Cited by 1,113

Über Triphenyl‐phosphin‐methylene als olefinbildende Reagenzien (I. Mitteil.

Wittig, G., & Schöllkopf, U. (1954) · Chemische Berichte · doi:10.1002/cber.19540870919 · Cited by 1,048

Resolvins and protectins in inflammation resolution

Serhan, C. N., & Petasis, N. A. (2011) · Chemical Reviews · doi:10.1021/cr100396c · Cited by 996

Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis

Nishimura, S. (2001) · Cited by 911

Simple and selective method for aldehydes (RCHO) .fwdarw. (E)-haloalkenes (RCH:CHX) conversion by means of a haloform-chromous chloride system

Takai, K., Nitta, K., & Utimoto, K. (1986) · Journal of the American Chemical Society · doi:10.1021/ja00283a046 · Cited by 750

CuH-Catalyzed Reactions

Deutsch, C., Krause, N., & Lipshutz, B. H. (2008) · Chemical Reviews · doi:10.1021/cr0684321 · Cited by 693

The modified Julia olefination: alkene synthesis via the condensation of metallated heteroarylalkylsulfones with carbonyl compounds

Blakemore, P. R. (2002) · Journal of the Chemical Society, Perkin Transactions 1 · doi:10.1039/b208078h · Cited by 646

Hydroborations catalysed by transition metal complexes

Beletskaya, I., & Pelter, A. (1997) · Tetrahedron · doi:10.1016/s0040-4020(97)00001-x · Cited by 619

Hydrogenation of carbon–carbon multiple bonds: chemo-, regio- and stereo-selectivity

Molnár, Á., Sárkány, A., & Varga, M. (2001) · Journal of Molecular Catalysis A: Chemical · doi:10.1016/s1381-1169(01)00150-9 · Cited by 616

Highly Selective Methods for Synthesis of Internal (α-) Vinylboronates through Efficient NHC–Cu-Catalyzed Hydroboration of Terminal Alkynes. Utility in Chemical Synthesis and Mechanistic Basis for Selectivity

Jang, H., Zhugralin, A. R., Lee, Y., & Hoveyda, A. H. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2007643 · Cited by 328

PALLADIUM CATALYST FOR PARTIAL REDUCTION OF ACETYLENES

(1966) · Organic Syntheses · doi:10.15227/orgsyn.046.0089 · Cited by 304

Alkyne hydrogenation over Pd catalysts: A new paradigm

TESCHNER, D., VASS, E., HAVECKER, M., ZAFEIRATOS, S., SCHNORCH, P., SAUER, H., KNOPGERICKE, A., SCHLOGL, R., CHAMAM, M., & WOOTSCH, A. (2006) · Journal of Catalysis · doi:10.1016/j.jcat.2006.05.030 · Cited by 290

Prostaglandin Syntheses by Three‐Component Coupling. New Synthetic Methods (49)

Noyori, R., & Suzuki, M. (1984) · Angewandte Chemie International Edition in English · doi:10.1002/anie.198408471 · Cited by 239

Carotenoids: Volume 2: Synthesis

(1996) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-9323-7 · Cited by 230

Sterospecific Syntheses and Spectroscopic Properties of Isomeric 2,4,6,8‐Undecatetraenes. New Hydrocarbons from the Marine Brown Alga Giffordia mitchellae. Part IV.

Boland, W., Schroer, N., Sieler, C., & Feigel, M. (1987) · Helvetica Chimica Acta · doi:10.1002/hlca.19870700415 · Cited by 210

Beyond Prostaglandins—Chemistry and Biology of Cyclic Oxygenated Metabolites Formed by Free‐Radical Pathways from Polyunsaturated Fatty Acids

Jahn, U., Galano, J., & Durand, T. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200705122 · Cited by 205

Catalysis‐Based Total Synthesis of Latrunculin B

Fürstner, A., De Souza, D., Parra‐Rapado, L., & Jensen, J. T. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200352413 · Cited by 172

A density functional theory study of the ‘mythic’ Lindlar hydrogenation catalyst

García‐Mota, M., Gómez-Díaz, J., Novell-Leruth, G., Vargas‐Fuentes, C., Bellarosa, L., Bridier, B., Pérez‐Ramírez, J., & López, N. (2010) · Theoretical Chemistry Accounts · doi:10.1007/s00214-010-0800-0 · Cited by 156

Mechanism of Pd(NHC)-Catalyzed Transfer Hydrogenation of Alkynes

Hauwert, P., Boerleider, R., Warsink, S., Weigand, J. J., & Elsevier, C. J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1062407 · Cited by 137

The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation

Roberts, L. J., & Fessel, J. P. (2003) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2003.09.016 · Cited by 128

Total Syntheses of the Actin‐Binding Macrolides Latrunculin A, B, C, M, S and 16‐epi‐Latrunculin B

Fürstner, A., Souza, D. D., Turet, L., Fenster, M. D. B., Rapado, L. P., Wirtz, C., MYNOTT, R. J., & Lehmann, C. W. (2006) · Chemistry - A European Journal · doi:10.1002/chem.200601135 · Cited by 128

Zr-Mediated hydroboration: stereoselective synthesis of vinyl boronic esters

Wang, Y. D., Kimball, G. M., Prashad, A. S., & Wang, Y. (2005) · Tetrahedron Letters · doi:10.1016/j.tetlet.2005.10.031 · Cited by 106

Synthesis of the Tricyclic Core of Eleutherobin and Sarcodictyins and Total Synthesis of Sarcodictyin A

Nicolaou, K. C., Xu, J.-Y., Kim, S., Ohshima, T., Hosokawa, S., & Pfefferkorn, J. A. (1997) · Journal of the American Chemical Society · doi:10.1021/ja973000g · Cited by 102

Pd nanoparticles in hydrotalcite: mild and highly selective catalysts for alkyne semihydrogenation

Mastalir, Á., & Király, Z. (2003) · Journal of Catalysis · doi:10.1016/s0021-9517(03)00269-0 · Cited by 96

Total Synthesis of Sarcodictyins A and B

Nicolaou, K. C., Xu, J. Y., Kim, S., Pfefferkorn, J. A., Ohshima, T., Vourloumis, D., & Hosokawa, S. (1998) · Journal of the American Chemical Society · doi:10.1021/ja981062g · Cited by 95

Factors Influencing the Autoxidation of Fatty Acids: Effect of Olefin Geometry of the Nonconjugated Diene

Tallman, K. A., Roschek, B., & Porter, N. A. (2004) · Journal of the American Chemical Society · doi:10.1021/ja049104q · Cited by 92

Rational design of a heterogeneous palladium catalyst for the selective hydrogenation of alkynes

Ulan, J. G., Maier, W. F., & Smith, D. A. (1987) · The Journal of Organic Chemistry · doi:10.1021/jo00390a032 · Cited by 91

(Z,Z)-4,7-Tridecadien-(S)-2-yl Acetate: Sex Pheromone of Douglas-Fir Cone Gall Midge, Contarinia oregonensis

Gries, R. M., Khaskin, G., Gries, G., Bennett, R. G., King, G. G. S., Morewood, P., Slessor, K. N., & Morewood, W. D. (2002) · Journal of Chemical Ecology · doi:10.1023/a:1021005517389 · Cited by 90

A fully stereocontrolled total synthesis of (+)-leucascandrolide A

Paterson, I., & Tudge, M. T. (2003) · Tetrahedron · doi:10.1016/s0040-4020(03)00814-7 · Cited by 88

Production of Octadienal in the Marine Diatom Skeletonema costatum

d’Ippolito, G., Romano, G., Caruso, T., Spinella, A., Cimino, G., & Fontana, A. (2003) · Organic Letters · doi:10.1021/ol034057c · Cited by 82

Total Synthesis and Bioactivity of Resolvin E2

Ogawa, S., Urabe, D., Yokokura, Y., Arai, H., Arita, M., & Inoue, M. (2009) · Organic Letters · doi:10.1021/ol901350g · Cited by 78

Pd/CaCO3 in liquid poly(ethylene glycol) (PEG): an easy and efficient recycle system for partial reduction of alkynes to cis-olefins under a hydrogen atmosphere

Chandrasekhar, S., Narsihmulu, C., Chandrashekar, G., & Shyamsunder, T. (2004) · Tetrahedron Letters · doi:10.1016/j.tetlet.2004.01.097 · Cited by 72

Synthesis and Biological Activity of Sarcodictyins

Nicolaou, K. C., Kim, S., Pfefferkorn, J. A., Xu, J., Ohshima, T., Hosokawa, S., Vourloumis, D., & Li, T. (1998) · Angewandte Chemie International Edition · Cited by 70

Design, synthesis and bioactions of novel stable mimetics of lipoxins and aspirin-triggered lipoxins

Petasis, N. A., Akritopoulou‐Zanze, I., Fokin, V. V., Bernasconi, G., Keledjian, R., Yang, R., Uddin, J., Venkata, K. C. N., & Serhan, C. N. (2005) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.05.020 · Cited by 68

Synthese von Carotinoiden II. Totalsynthese des β‐Carotins I

Karrer, P., & Eugster, C. H. (1950) · Helvetica Chimica Acta · doi:10.1002/hlca.19500330507 · Cited by 62

The inhibitory mechanism of bovine pancreatic phospholipase A2 by aldehyde terpenoids

Tanaka, K., Kamatani, M., Mori, H., Fujii, S., Ikeda, K., Hisada, M., Itagaki, Y., & Katsumura, S. (1999) · Tetrahedron · doi:10.1016/s0040-4020(98)01197-1 · Cited by 61

Controlled Semihydrogenation of Aminoalkynes Using Ethylenediamine as a Poison of Lindlar's Catalyst

Campos, K. R., Cai, D., Journet, M., Kowal, J. J., Larsen, R. D., & Reider, P. J. (2001) · The Journal of Organic Chemistry · doi:10.1021/jo015514a · Cited by 60

One-Pot o-Nitrobenzenesulfonylhydrazide (NBSH) Formation−Diimide Alkene Reduction Protocol

Marsh, B. J., & Carbery, D. R. (2009) · The Journal of Organic Chemistry · doi:10.1021/jo900237y · Cited by 54

A General Strategy for the Synthesis of Monohydroxy-eicosatetraenoic Acids: Total Synthesis of 5(S)-Hydroxy-6(E),8,11,14(Z)-eicosatetraenoic Acid (5-HETE) and 12(S)-Hydroxy-5,8,14(Z), 10(E)-eicosatetraenoic Acid (12-HETE)

Nicolaou, K. C., Ladduwahetty, T., Taffer, I. M., et al. (1986) · Synthesis · doi:10.1055/s-1986-31612 · Cited by 49

A short stereocontrolled synthesis of leukotriene B4

Chemin, D., & Linstrumelle, G. (1992) · Tetrahedron · doi:10.1016/s0040-4020(01)88516-1 · Cited by 46

First total synthesis of 7(S),17(S)-Resolvin D5, a potent anti-inflammatory docosanoid

Rodrı́guez, A. R., & Spur, B. W. (2005) · Tetrahedron Letters · doi:10.1016/j.tetlet.2005.03.175 · Cited by 46

Stereocontrolled total synthesis of neuroprotectin D1/protectin D1 and its aspirin-triggered stereoisomer

Petasis, N. A., Yang, R., Winkler, J. W., Zhu, M., Uddin, J., Bazan, N. G., & Serhan, C. N. (2012) · Tetrahedron Letters · doi:10.1016/j.tetlet.2012.01.032 · Cited by 45

Preparation, Modification, and Evaluation of Cruentaren A and Analogues

Bindl, M., Jean, L., Herrmann, J. E., Müller, R., & Fürstner, A. (2009) · Chemistry - A European Journal · doi:10.1002/chem.200901817 · Cited by 45

Palladium Nanohexagons and Nanospheres in Selective Alkyne Hydrogenation

Semagina, N., & Kiwi‐Minsker, L. (2008) · Catalysis Letters · doi:10.1007/s10562-008-9684-1 · Cited by 44

Hydrolytic kinetic resolution of terminal mono- and bis-epoxides in the synthesis of insect pheromones: routes to (−)-(R)- and (+)-(S)-10-methyldodecyl acetate, (−)-(R)-10-methyl-2-tridecanone, (−)-(R)-(Z)-undec-6-en-2-ol (Nostrenol), (−)-(1R,7R)-1,7-dimethylnonyl propanoate, (−)-(6R,12R)-6,12-dimethylpentadecan-2-one, (−)-(2S,11S)-2,11-diacetoxytridecane and (+)-(2S,12S)-2,12-diacetoxytridecane

Chow, S., & Kitching, W. (2002) · Tetrahedron Asymmetry · doi:10.1016/s0957-4166(02)00175-1 · Cited by 43

Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogs

Kerdesky, F. A. J., Schmidt, S. P., Holms, J. H., et al. (1987) · Journal of Medicinal Chemistry · doi:10.1021/jm00390a010 · Cited by 42

Improved stereoselective reduction of a E,E, conjugated dienyne to a E,E,Z conjugated triene

Tropis, M., & Pougny, J.-R. (1989) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)80551-7 · Cited by 41

Synthesis and antitumor-evaluation of cyclopropyl-containing combretastatin analogs

Fürst, R., Zupkó, I., Berényi, Á., Ecker, G. F., & Rinner, U. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.10.064 · Cited by 41

An efficient total synthesis of 5-(S)-HETE

Gueugnot, S., Alami, M., Linstrumelle, G., Mambu, L., Petit, Y., & LARCHEVÊQUE, M. (1996) · Tetrahedron · doi:10.1016/0040-4020(96)00316-x · Cited by 39

Isotope Sensitive Branching and Kinetic Isotope Effects in the Reaction of Deuterated Arachidonic Acids with Human 12- and 15-Lipoxygenases

Jacquot, C., Wecksler, A. T., McGinley, C. M., Segraves, E. N., Holman, T. R., & van der Donk, W. A. (2008) · Biochemistry · doi:10.1021/bi800308q · Cited by 36

Total synthesis of the antiinflammatory and proresolving protectin D1

Ogawa, N., & Kobayashi, Y. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2011.03.152 · Cited by 36

First total synthesis of the anti-inflammatory lipid mediator Resolvin D6

Rodrı́guez, A. R., & Spur, B. W. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2011.11.003 · Cited by 35

Total synthesis of Resolvin E1

Allard, M. L., Barnes, K. D., Chen, X., Cheung, Y., Duffy, B. C., Heap, C. R., Inthavongsay, J., Johnson, M., Krishnamoorthy, R., Manley, C., et al. (2011) · Tetrahedron Letters · doi:10.1016/j.tetlet.2011.03.035 · Cited by 34

Efficient Synthesis of 11-cis-Retinoids

Borhan, B., Souto, M. L., Um, J. M., Zhou, B., & Nakanishi, K. (1999) · Chemistry - A European Journal · doi:10.1002/(sici)1521-3765(19990401)5:4<1172::aid-chem1172>3.0.co;2-q · Cited by 33

Laurencenyne, a plausible precursor of various nonterpenoid C15-compounds, and neolaurencenyne from the red alga

Kigoshi, H., Shizuri, Y., Niwa, H., et al. (1981) · Tetrahedron Letters · doi:10.1016/s0040-4039(01)83025-2 · Cited by 32

The Synthesis of N-Vanillyl-arachidonoyl-amide (Arvanil) and its Analogs: An Improved Procedure for the Synthesis of the Key Synthon Methyl 14-Hydroxy-(all-cis)-5,8,11-tetradecatrienoate

Dasse, O. A., Mahadevan, A., Han, L., Martin, B. R., Marzo, V. D., & Razdan, R. K. (2000) · Tetrahedron · doi:10.1016/s0040-4020(00)00877-2 · Cited by 32

Structure–activity relationship study of flowering-inducer FN against Lemna paucicostata

Kai, K., Takeuchi, J., Kataoka, T., Yokoyama, M., & Watanabe, N. (2008) · Tetrahedron · doi:10.1016/j.tet.2008.04.115 · Cited by 28

Substituent Effects on Regioselectivity in the Autoxidation of Nonconjugated Dienes

Tallman, K. A., Rector, C. L., & Porter, N. A. (2009) · Journal of the American Chemical Society · doi:10.1021/ja900040d · Cited by 28

Hydrolytic kinetic resolution of mono- and bisepoxides as a key step in the synthesis of insect pheromones

Chow, S., & Kitching, W. (2001) · Chemical Communications · doi:10.1039/b102181h · Cited by 27

Identification of very-long-chain polyunsaturated fatty acids from Amphidinium carterae by atmospheric pressure chemical ionization liquid chromatography–mass spectroscopy

Řezanka, T., Nedbalová, L., & Sigler, K. (2008) · Phytochemistry · doi:10.1016/j.phytochem.2008.06.011 · Cited by 27

Total synthesis of (+)-Leukotriene B4 methyl ester and its 5-epimer from (R)-glycidol

Avignon‐Tropis, M., Treilhou, M., Pougny, J.-R., et al. (1991) · Tetrahedron · doi:10.1016/s0040-4020(01)89730-1 · Cited by 26

Enantiomeric Propanolamines as selectiveN-Methyl- d -aspartate 2B Receptor Antagonists

Tahirovic, Y. A., Geballe, M. T., Gruszecka‐Kowalik, E., Myers, S. J., Lyuboslavsky, P. N., Le, P., French, A. M., Irier, H. A., Choi, W., Easterling, K. W., et al. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm8002153 · Cited by 26

Development of the First Potential Covalent Inhibitors of Anandamide Cellular Uptake

Moriello, A. S., Balas, L., Ligresti, A., Cascio, M. G., Durand, T., Morera, E., Ortar, G., & Marzo, V. D. (2006) · Journal of Medicinal Chemistry · doi:10.1021/jm051226l · Cited by 24

Total synthesis of the anti-inflammatory lipid mediator Resolvin E2

Rodrı́guez, A. R., & Spur, B. W. (2012) · Tetrahedron Letters · doi:10.1016/j.tetlet.2012.01.136 · Cited by 24

Synthesis of Site-Specifically Labeled Arachidonic Acids as Mechanistic Probes for Prostaglandin H Synthase

Peng, S., McGinley, C. M., & van der Donk, W. A. (2004) · Organic Letters · doi:10.1021/ol0361711 · Cited by 22

A versatile to conjugated hydroxy (E, Z, E, E)-tetraenoic acids: highly chemo- and stereoselective synthesis of lipoxin B4

Alami, M., Crousse, B., Linstrumelle, G., Mambu, L., & LARCHEVÊQUE, M. (1997) · Tetrahedron Asymmetry · doi:10.1016/s0957-4166(97)00333-9 · Cited by 18

Synthesis of new carbo- and heterocyclic analogues of 8-HETE and evaluation of their activity towards the PPARs

Caïjo, F., Mosset, P., Gree, R. L., Audinot, V., Boutin, J. A., Renard, P., Caignard, D., & Dacquet, C. (2005) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2005.07.049 · Cited by 17

Design and Synthesis of (13S)‐Methyl‐Substituted Arachidonic Acid Analogues: Templates for Novel Endocannabinoids

Papahatjis, D. P., Nahmias, V. R., Nikas, S. P., Schimpgen, M., & Makriyannis, A. (2010) · Chemistry - A European Journal · doi:10.1002/chem.200902880 · Cited by 16

(Z)-Selektive Reduktion von konjugierten Dreifachbindungen mit Zn (Cu/Ag)

Boland, W., & Pantke, S. (1994) · Journal für praktische Chemie · doi:10.1002/prac.19943360817 · Cited by 15

Synthesis and biological evaluation of several structural analogs of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand

Suhara, Y., Oka, S., Kittaka, A., et al. (2006) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2006.10.049 · Cited by 14

Novel selective catalytic reduction with tritium: Synthesis of the GABAA receptor radioligand 1‐(4‐ethynylphenyl)‐4‐[2,3‐3H2]propyl‐2,6,7‐trioxabicyclo[2.2.2]octane

Palmer, C. J., & Casida, J. E. (1991) · Journal of Labelled Compounds and Radiopharmaceuticals · doi:10.1002/jlcr.2580290714 · Cited by 13

A synthon for C‐20 trideuterated eicosanoids: Preparation of [2H3]‐arachidonic acid

Prakash, C., Saleh, S., Sweetman, B. J., Taber, D. F., & Blair, I. A. (1989) · Journal of Labelled Compounds and Radiopharmaceuticals · doi:10.1002/jlcr.2580270507 · Cited by 9