The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Beyond Prostaglandins—Chemistry and Biology of Cyclic Oxygenated Metabolites Formed by Free‐Radical Pathways from Polyunsaturated Fatty Acids
Abstract
Polyunsaturated fatty acids (PUFAs) are important constituents in all organisms. They fulfil many functions, ranging from modulating the structure of membranes to acting as precursors of physiologically important molecules, such as the prostaglandins, which for a long time were the most prominent cyclic PUFA metabolites. However, since the beginning of the 1990s a large variety of cyclic metabolites have been discovered that form under autoxidative conditions in vivo to a much larger extent than do prostaglandins. These compounds—isoprostanes, neuroprostanes, phytoprostanes, and isofurans—proved subsequently to be ubiquitous in nature. They display a wide range of biological activities, and isoprostanes have become the currently most reliable indicators of oxidative stress in humans. In a relatively short time, the structural variety, properties, and applications of the autoxidatively formed cyclic PUFA derivatives have been uncovered.
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Cites
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4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
Uchida, K. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00014-6 · Cited by 1,164
Essential Fatty Acids: Biochemistry, Physiology and Pathology
Das, U. N. (2006) · Biotechnology Journal · doi:10.1002/biot.200600012 · Cited by 650
Isoprostanes: Potential Markers of Oxidant Stress in Atherothrombotic Disease
Patrono, C., & FitzGerald, G. A. (1997) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.17.11.2309 · Cited by 453
Life — As a Matter of Fat: The Emerging Science of Lipidomics
Mouritsen, O. G. (2005) · The Frontiers Collection · doi:10.1007/b138577 · Cited by 448
Increased F 2 ‐isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo
Pratico, D., Lee, V. M.-Y., Trojanowski, J. Q., Rokach, J., & Fitzgerald, G. A. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.15.1777 · Cited by 405
Increased excretion of a lipid peroxidation biomarker in autism
Ming, X., Stein, T. P., Brimacombe, M., Johnson, W. G., Lambert, G. H., & Wagner, G. C. (2005) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2005.06.002 · Cited by 236
What Is Responsible for the Initiating Chemistry of Iron-Mediated Lipid Peroxidation: An Update
Cheng, Z., & Li, Y. (2007) · Chemical Reviews · doi:10.1021/cr040077w · Cited by 211
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Cited by
The wanderings of a free radical
Halliwell, B. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.11.008 · Cited by 467
Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers
Giustarini, D., Dalle-Donne, I., Tsikas, D., & Rossi, R. (2009) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408360903142326 · Cited by 440
Oger, C., Balas, L., Durand, T., & Galano, J.-M. (2013) · Chemical Reviews · doi:10.1021/cr3001753 · Cited by 396
Self-citationPratt, D. A., Tallman, K. A., & Porter, N. A. (2011) · Accounts of Chemical Research · doi:10.1021/ar200024c · Cited by 352
Metadata
- Authors
- Jahn, U., Galano, J., & Durand, T.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2008-07-22
- Volume
- 47
- Issue
- 32
- Pages
- 5894-5955
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2114381382
- Cited by
- 205
- References
- 9
- FWCI
- 8.25
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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