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Antibacterial Activity of Fullerene Water Suspensions: Effects of Preparation Method and Particle Size
Abstract
Fullerene research in biological systems has been hindered by the compound's relative insolubility in water. However, C60 molecules can be made to aggregate, forming stable fullerene water suspensions (FWS) whose properties differ from those of bulk solid C60. There are many different protocols for making FWS. This paper explores four of these methods and establishes the antibacterial activity of each resulting suspension, including a suspension made without intermediary solvents. The aggregates in each polydisperse suspension were separated by size using differential centrifugation and tested for antibacterial activity using Bacillus subtilis as a test organism. All suspensions exhibited relatively strong antibacterial activity. Fractions containing smaller aggregates had greater antibacterial activity, although the increase in toxicity was disproportionately higher than the associated increase in putative surface area. This suggests the need for improved understanding of the behavior of FWS towards organisms and in the environment to determine how C60 can be safely used and disposed.
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Cites
Kroto, H. W., Heath, J. R., O’Brien, S. C., Curl, R. F., & Smalley, R. E. (1985) · Nature · doi:10.1038/318162a0 · Cited by 16,083
Solid C60: a new form of carbon
Krätschmer, W., Lamb, L. D., Fostiropoulos, K., & Huffman, D. R. (1990) · Nature · doi:10.1038/347354a0 · Cited by 7,646
Handbook of Microbiological Media
Atlas, R. M., & Atlas, R. M. (2004) · CRC Press eBooks · doi:10.1201/9781420039726 · Cited by 2,149
Cytotoxicity of Carbon Nanomaterials: Single-Wall Nanotube, Multi-Wall Nanotube, and Fullerene
Jia, G., Wang, H., Yan, L., Wang, X., Pei, R., Yan, T., Zhao, Y., & Guo, X. (2005) · Environmental Science & Technology · doi:10.1021/es048729l · Cited by 1,404
Oberdörster, E. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7021 · Cited by 1,393
The Differential Cytotoxicity of Water-Soluble Fullerenes
Sayes, C. M., Fortner, J. D., Guo, W., Lyon, D., Boyd, A. M., Ausman, K. D., Tao, Y. J., Sitharaman, B., Wilson, L. J., Hughes, J. B., et al. (2004) · Nano Letters · doi:10.1021/nl0489586 · Cited by 1,087
Self-citationRich, D. P., Anderson, M. P., Gregory, R. J., Cheng, S. H., Paul, S., Jefferson, D. M., McCann, J. D., Klinger, K. W., Smith, A. E., & Welsh, M. J. (1990) · Nature · doi:10.1038/347358a0 · Cited by 708
Nano-C60 cytotoxicity is due to lipid peroxidation
Sayes, C. M., Gobin, A. M., Ausman, K. D., Mendez, J., West, J. L., & Colvin, V. L. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.05.027 · Cited by 686
C60 in Water: Nanocrystal Formation and Microbial Response
Fortner, J. D., Lyon, D. Y., Sayes, C. M., Boyd, A. M., Falkner, J. C., Hotze, E. M., Alemany, L. B., Tao, Y. J., Guo, W., Ausman, K. D., et al. (2005) · Environmental Science & Technology · doi:10.1021/es048099n · Cited by 666
Self-citationPhotoinduced biochemical activity of fullerene carboxylic acid
Tokuyama, H., Yamago, S., Nakamura, E., Shiraki, T., & Sugiura, Y. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00070a064 · Cited by 619
Stable Dispersions of Fullerenes, C60 and C70, in Water. Preparation and Characterization
Deguchi, S., Alargova, R. G., & Tsujii, K. (2001) · Langmuir · doi:10.1021/la010651o · Cited by 506
Handbook of microbiological media
Corry, J. E. L. (1994) · International Journal of Food Microbiology · doi:10.1016/0168-1605(94)90011-6 · Cited by 415
Aggregation and Deposition Characteristics of Fullerene Nanoparticles in Aqueous Systems
Brant, J., Lecoanet, H., & Wiesner, M. R. (2005) · Journal of Nanoparticle Research · doi:10.1007/s11051-005-4884-8 · Cited by 353
Bacterial cell association and antimicrobial activity of a C60 water suspension
Lyon, D. Y., Fortner, J. D., Sayes, C. M., Colvin, V. L., & Hughes, J. B. (2005) · Environmental Toxicology and Chemistry · doi:10.1897/04-649r.1 · Cited by 275
Self-citationSolubilization of fullerenes into water with polyvinylpyrrolidone applicable to biological tests
Yamakoshi, Y. N., Yagami, T., Fukuhara, K., Sueyoshi, S., & Miyata, N. (1994) · Journal of the Chemical Society, Chemical Communications · doi:10.1039/c39940000517 · Cited by 267
Environmental Inorganic Chemistry: Properties, Processes, and Estimation Methods
Bodek, I. (1989) · Cited by 263
Kamat, J. (2000) · Toxicology · doi:10.1016/s0300-483x(00)00277-8 · Cited by 252
Naphthalene Adsorption and Desorption from Aqueous C60 Fullerene
Cheng, X., Kan, A. T., & Tomson, M. B. (2004) · Journal of Chemical & Engineering Data · doi:10.1021/je030247m · Cited by 250
Comparison of Electrokinetic Properties of Colloidal Fullerenes (n-C60) Formed Using Two Procedures
Brant, J., Lecoanet, H., Hotze, M., & Wiesner, M. (2005) · Environmental Science & Technology · doi:10.1021/es050090d · Cited by 231
Electronic properties of doped fullerenes
Forró, L., & Mihály, L. (2001) · Reports on Progress in Physics · doi:10.1088/0034-4885/64/5/202 · Cited by 228
Novel harmful effects of [60]fullerene on mouse embryos in vitro and in vivo
Tsuchiya, T., Oguri, I., Yamakoshi, Y. N., & Miyata, N. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00812-5 · Cited by 226
Fullerene inhibits β-amyloid peptide aggregation
Kim, J. E., & Lee, M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00393-0 · Cited by 212
Is the C60 Fullerene Molecule Toxic?!
Andrievsky, G., Klochkov, V., & Derevyanchenko, L. (2005) · Fullerenes, Nanotubes and Carbon Nanostructures · doi:10.1080/15363830500237267 · Cited by 196
In vitro action of carboxyfullerene
Tsao, N., Luh, T., Chou, C., Chang, T.-Y., Wu, J.-J., Liu, C.-C., & Lei, H. (2002) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/49.4.641 · Cited by 154
Studies of aqueous colloidal solutions of fullerene C60 by electron microscopy
Andrievsky, G. V., Klochkov, V., Karyakina, E. L., & Mchedlov‐Petrossyan, N. O. (1999) · Chemical Physics Letters · doi:10.1016/s0009-2614(98)01393-1 · Cited by 153
Antibacterial and antiproliferative activity of cationic fullerene derivatives
Mashino, T., Nishikawa, D., Takahashi, K., Usui, N., Yamori, T., Seki, M., Endō, T., & Mochizuki, M. (2003) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2003.09.040 · Cited by 146
Antimycobacterial activity of ionic fullerene derivatives
Bosi, S., Ros, T. D., Castellano, S., Banfi, E., & Prato, M. (2000) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(00)00159-1 · Cited by 133
Mutagenicity of the fullerene C60-generated singlet oxygen dependent formation of lipid peroxides
Sera, N., Tokiwa, H., & Miyata, N. (1996) · Carcinogenesis · doi:10.1093/carcin/17.10.2163 · Cited by 129
Photo-induced cytotoxicity of malonic acid [C60]fullerene derivatives and its mechanism
Yang, X., Fan, C., & Zhu, H. (2002) · Toxicology in Vitro · doi:10.1016/s0887-2333(01)00102-3 · Cited by 124
Tissue Sites of Uptake of14C-Labeled C60
Bullard-Dillard, R., Creek, K. E., Scrivens, W. A., & Tour, J. M. (1996) · Bioorganic Chemistry · doi:10.1006/bioo.1996.0032 · Cited by 113
Inhibition of Group A Streptococcus Infection by Carboxyfullerene
Tsao, N., Luh, T., Chou, C., Wu, J.-J., Lin, Y.-S., & Lei, H.-Y. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.6.1788-1793.2001 · Cited by 96
Inhibition ofEscherichia coli-Induced Meningitis by Carboxyfullerence
Tsao, N., Kanakamma, P. P., Luh, T., Chou, C., & Lei, H. (1999) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.43.9.2273 · Cited by 96
Pessini, G. L., Filho, B. P. D., Nakamura, C. V., et al. (2003) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762003000800025 · Cited by 93
FULLERENES AND FULLERENE-BASED MATERIALS IN CATALYSIS
Goldshleger, N. F. (2001) · Fullerene Science and Technology · doi:10.1081/fst-100104493 · Cited by 73
Mashino, T., Usui, N., Okuda, K., Hirota, T., & Mochizuki, M. (2003) · Bioorganic & Medicinal Chemistry · doi:10.1016/s0968-0896(02)00610-7 · Cited by 73
[60]Fullerene as a Novel Photoinduced Antibiotic
Kai, Y., Komazawa, Y., Miyajima, A., Miyata, N., & Yamakoshi, Y. N. (2003) · Fullerenes Nanotubes and Carbon Nanostructures · doi:10.1081/fst-120018664 · Cited by 42
Babynin, E. V., Нуретдинов, И. А., Gubskaya, V. P., et al. (2002) · Russian Journal of Genetics · doi:10.1023/a:1015237916596 · Cited by 27
Foley, S., Curtis, A. D. M., Hirsch, A., Brettreich, M., Pèlegrin, A., Patrick, S. E. T. A., & Larroque, C. (2002) · Fullerenes Nanotubes and Carbon Nanostructures · doi:10.1081/fst-120002929 · Cited by 21
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Self-citationBanerjee, I., Pangule, R. C., & Kane, R. S. (2011) · Advanced Materials · doi:10.1002/adma.201001215 · Cited by 2,749
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Metadata
- Authors
- Lyon, D. Y., Adams, L. K., Falkner, J. C., & Alvarez, P. J. J.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-04-13
- Volume
- 40
- Issue
- 14
- Pages
- 4360-4366
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2050091149
- Cited by
- 555
- References
- 38
- FWCI
- 21.34
- Type
- journal article
- Language
- en
- Open access
- closed
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