The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Redox Reactions of Phenazine Antibiotics with Ferric (Hydr)oxides and Molecular Oxygen
Open accessAbstract
Phenazines are small redox-active molecules produced by a variety of bacteria. Beyond merely serving as antibiotics, recent studies suggest that phenazines play important physiological roles, including one in iron acquisition. Here we characterize the ability of four electrochemically reduced natural phenazines--pyocyanin (PYO), phenazine-1-carboxylate (PCA), phenazine-1-carboxamide, and 1-hydroxyphenazine (1-OHPHZ)--to reductively dissolve ferrihydrite and hematite in the pH range 5-8. Generally, the reaction rate is higher for a phenazine with a lower reduction potential, with the reaction between PYO and ferrihydrite at pH 5 being an exception; the rate decreases as the pH increases; the rate is higher for poorly crystalline ferrihydrite than for highly crystalline hematite. Ferric (hydr)oxide reduction by reduced phenazines can potentially be inhibited by oxygen, where O2 competes with Fe(III) as the final oxidant The reactivity of reduced phenazines with 02 decreases in the order: PYO > 1-OHPHZ > PCA. Strikingly, reduced PYO,which isthe least reactive phenazine with ferrihydrite and hematite at pH 7, is the most reactive phenazine with O2. These results imply that different phenazines may perform different functions in environments with gradients of iron and O2.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
Two simple media for the demonstration of pyocyanin and fluorescin.
Eo, K., WARD, M. K., & De, R. (1954) · PubMed · Cited by 5,234
The Iron Oxides: Structure, Properties, Reactions, Occurences and Uses
Cornell, R. M., & Schwertmann, U. (2003) · doi:10.1002/3527602097 · Cited by 4,422
Electrochemical methods, fundamentals and applications
Aikens, D. A. (1983) · Journal of Chemical Education · doi:10.1021/ed060pa25.1 · Cited by 3,139
Biological control of soil-borne pathogens by fluorescent pseudomonads
Haas, D., & Défago, G. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1129 · Cited by 2,598
Extracellular electron transfer via microbial nanowires
Reguera, G., McCarthy, K. D., Mehta, T., Nicoll, J. S., Tuominen, M. T., & Lovley, D. R. (2005) · Nature · doi:10.1038/nature03661 · Cited by 2,585
Iron oxides in the laboratory: preparation and characterization
(1992) · Choice Reviews Online · doi:10.5860/choice.29-2718 · Cited by 2,259
Water Analysis: Emerging Contaminants and Current Issues
Richardson, S. D., & Ternes, T. A. (2014) · Analytical Chemistry · doi:10.1021/ac500508t · Cited by 2,144
Humic substances as electron acceptors for microbial respiration
Lovley, D. R., Coates, J. D., Blunt-Harris, E. L., Phillips, E. J. P., & Woodward, J. C. (1996) · Nature · doi:10.1038/382445a0 · Cited by 1,834
Dissimilatory Fe(III) and Mn(IV) reduction
Lovley, D. R. (1991) · Microbiological Reviews · doi:10.1128/mr.55.2.259-287.1991 · Cited by 1,661
Stewart, P. S. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.5.1485-1491.2003 · Cited by 1,178
Worlitzsch, D., Tarran, R., Ulrich, M., Schwab, U. E., Cekici, A., Meyer, K. C., Birrer, P., Bellon, G., Berger, J., Weiß, T., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci13870 · Cited by 1,099
Microbial Phenazine Production Enhances Electron Transfer in Biofuel Cells
Rabaey, K., Boon, N., Höfte, M., & Verstraete, W. (2005) · Environmental Science & Technology · doi:10.1021/es048563o · Cited by 998
(2000) · Wiley-VCH eBooks · doi:10.1002/9783527613229 · Cited by 940
Worlitzsch, D., Tarran, R., Ulrich, M., Schwab, U., Cekici, A., Meyer, K. C., Birrer, P., Bellon, G., Berger, J., Weiss, T., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0213870 · Cited by 932
A role for excreted quinones in extracellular electron transfer
Newman, D. K., & Kolter, R. (2000) · Nature · doi:10.1038/35011098 · Cited by 884
Self-citationThomashow, L. S., & Weller, D. M. (1988) · Journal of Bacteriology · doi:10.1128/jb.170.8.3499-3508.1988 · Cited by 727
Dietrich, L. E. P., Price‐Whelan, A., Petersen, A., Whiteley, M., & Newman, D. K. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05306.x · Cited by 713
Self-citationThe role of pyocyanin in Pseudomonas aeruginosa infection
Lau, G. W., Hassett, D. J., Ran, H., & Kong, F. (2004) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2004.10.002 · Cited by 688
Principles and applications of aquatic chemistry
Wangersky, J. (1994) · Journal of Hydrology · doi:10.1016/0022-1694(94)90170-8 · Cited by 668
Rethinking 'secondary' metabolism: physiological roles for phenazine antibiotics
Price-Whelan, A., Dietrich, L. E. P., & Newman, D. K. (2006) · Nature Chemical Biology · doi:10.1038/nchembio764 · Cited by 584
Self-citationExtracellular electron transfer
Hernandez, M. E., & Newman, D. K. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000796 · Cited by 579
Self-citationReductive Dissolution of Manganese(III/Iv) Oxides by Substituted Phenols
Stone, A. T. (1987) · Environmental Science & Technology · doi:10.1021/es50001a011 · Cited by 523
Mehta, T., Coppi, M. V., Childers, S. E., & Lovley, D. R. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.12.8634-8641.2005 · Cited by 494
Bacterial solutions to the iron-supply problem
Braun, V., & Killmann, H. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01359-6 · Cited by 408
Phenazines and Other Redox-Active Antibiotics Promote Microbial Mineral Reduction
Hernandez, M. E., Kappler, A., & Newman, D. K. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.2.921-928.2004 · Cited by 407
Self-citationChin-A-Woeng, T. F. C., Bloemberg, G. V., van der Bij, A. J., van der Drift, K. M. G. M., Schripsema, J., Kroon, B., Scheffer, R. J., Keel, C., Bakker, P. A. H. M., Tichy, H.-V., et al. (1998) · Molecular Plant-Microbe Interactions® · doi:10.1094/mpmi.1998.11.11.1069 · Cited by 363
Nevin, K. P., & Lovley, D. R. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.5.2294-2299.2002 · Cited by 359
Lies, D. P., Hernandez, M. E., Kappler, A., Mielke, R. E., Gralnick, J. A., & Newman, D. K. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.8.4414-4426.2005 · Cited by 335
Self-citationPrice-Whelan, A., Dietrich, L. E. P., & Newman, D. K. (2007) · Journal of Bacteriology · doi:10.1128/jb.00505-07 · Cited by 315
Self-citationOccurrence, Biochemistry and Physiology of Phenazine Pigment Production
Turner, J. M., & Messenger, A. J. (1986) · Advances in Microbial Physiology · doi:10.1016/s0065-2911(08)60306-9 · Cited by 289
Water Analysis: Emerging Contaminants and Current Issues
Richardson, S. D. (2007) · Analytical Chemistry · doi:10.1021/ac070719q · Cited by 233
Nurmi, J. T., & Tratnyek, P. G. (2002) · Environmental Science & Technology · doi:10.1021/es0110731 · Cited by 231
Hunter, R. C., & Beveridge, T. J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.5.2501-2510.2005 · Cited by 208
Fe(II) Sorption on Hematite: New Insights Based on Spectroscopic Measurements
Larese-Casanova, P., & Scherer, M. M. (2007) · Environmental Science & Technology · doi:10.1021/es0617035 · Cited by 199
Finnan, S., Morrissey, J. P., O'Gara, F., & Boyd, E. F. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.12.5783-5792.2004 · Cited by 192
Role of pyocyanin in the acquisition of iron from transferrin
Cox, C. D. (1986) · Infection and Immunity · doi:10.1128/iai.52.1.263-270.1986 · Cited by 182
Komadel, P., & Stucki, J. W. (1988) · Clays and Clay Minerals · doi:10.1346/ccmn.1988.0360415 · Cited by 180
Kinetics and Mechanisms for Reactions of Fe(II) with Iron(III) Oxides
Jeon, B., Dempsey, B. A., & Burgos, W. D. (2003) · Environmental Science & Technology · doi:10.1021/es025900p · Cited by 171
van Rij, T., Wesselink, M., Chin‐A‐Woeng, T. F. C., et al. (2004) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi.2004.17.5.557 · Cited by 136
Surface Changes in Mild Steel Coupons from the Action of Corrosion-Causing Bacteria
Obuekwe, C. O., Westlake, D. W. S., Cook, F. D., et al. (1981) · Applied and Environmental Microbiology · doi:10.1128/aem.41.3.766-774.1981 · Cited by 83
Iron, Pseudomonas aeruginosa and cystic fibrosis
Reid, D. W., & Kirov, S. M. (2004) · Microbiology · doi:10.1099/mic.0.26804-0 · Cited by 15
Iron availability, oxygen limitation, Pseudomonas aeruginosa and cystic fibrosis
Zeng, A., & Kim, E.-J. (2004) · Microbiology · doi:10.1099/mic.0.26933-0 · Cited by 7
Cited by
Pierson, L. S., & Pierson, E. A. (2010) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-2509-3 · Cited by 560
Saunders, S. H., Tse, E. C. M., Yates, M. D., Otero, F. J., Trammell, S. A., Stemp, E. D. A., Barton, J. K., Tender, L. M., & Newman, D. K. (2020) · Cell · doi:10.1016/j.cell.2020.07.006 · Cited by 328
Self-citationGradients and consequences of heterogeneity in biofilms
Jo, J., Price-Whelan, A., & Dietrich, L. E. P. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00692-2 · Cited by 319
Bacterial community morphogenesis is intimately linked to the intracellular redox state
Dietrich, L. E. P., Okegbe, C., Price-Whelan, A., Sakhtah, H., Hunter, R. C., & Newman, D. K. (2013) · Journal of Bacteriology · doi:10.1128/jb.02273-12 · Cited by 291
Self-citationMicrobial electrocatalysis: Redox mediators responsible for extracellular electron transfer
Liu, X., Shi, L., & Gu, J.-D. (2018) · Biotechnology Advances · doi:10.1016/j.biotechadv.2018.07.001 · Cited by 267
Metadata
- Authors
- Wang, Y., & Newman, D. K.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02-20
- Volume
- 42
- Issue
- 7
- Pages
- 2380-2386
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2034613935
- Cited by
- 279
- References
- 43
- FWCI
- 10.49
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
