The DOI matches its Crossref record.
Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in Trout and Roach
Abstract
The occurrence of certain natural and synthetic steroidal estrogens in the final effluent from STW has been demonstrated. 17β-Estradiol and estrone were present at concentrations in the tens of nanograms per liter range, and the synthetic estrogen 17α-ethynylestradiol was also identified, albeit in the low nanogram per liter range. The findings from subsequent in vivo tank trial experiments, in which adult male rainbow trout ( Oncorhynchus mykiss ) and adult roach ( Rutilus rutilus ) were exposed for 21 days via the water to environmentally relevant concentrations of 17β-estradiol and estrone are presented. In addition, the response of adult male and female roach following exposure to 17β-estradiol (1, 10, and 100 ng/L) was compared to the response to the alkylphenolic xenoestrogen, 4- tert -octylphenol (1, 10 and 100 μg/L). Plasma levels of vitellogenin were determined using previously validated radioimmunoassays in order to measure the estrogenic response of the fish to the varying concentrations of the compounds tested. The results indicate that environmentally relevant concentra tions of natural steroidal estrogens are sufficient to account for the levels of vitellogenin synthesis observed in caged male fish placed downstream of certain STW effluent discharges in British rivers.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Water Analysis: Emerging Contaminants and Current Issues
Richardson, S. D., & Ternes, T. A. (2014) · Analytical Chemistry · doi:10.1021/ac500508t · Cited by 2,144
Ahmed, S. F., Mofijur, M., Nuzhat, S., Chowdhury, A. T., Rafa, N., Uddin, M. A., Inayat, A., Mahlia, T. M. I., Ong, H. C., Chia, W. Y., et al. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.125912 · Cited by 965
Baronti, C., Curini, R., D'Ascenzo, G., Di Corcia, A., Gentili, A., & Samperi, R. (2000) · Environmental Science & Technology · doi:10.1021/es001359q · Cited by 965
Kuch, H. M., & Ballschmiter, K. (2001) · Environmental Science & Technology · doi:10.1021/es010034m · Cited by 734
Ternes, T. A., Kreckel, P., & Mueller, J. (1999) · Science of The Total Environment · doi:10.1016/s0048-9697(98)00335-0 · Cited by 734
Nash, J. P., Kime, D. E., Van der Ven, L. T. M., Wester, P. W., Brion, F., Maack, G., Stahlschmidt-Allner, P., & Tyler, C. R. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7209 · Cited by 664
Endocrine disruptors and human health--is there a problem? An update.
Safe, S. H. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108487 · Cited by 351
Parrott, J. L., & Blunt, B. R. (2005) · Environmental Toxicology · doi:10.1002/tox.20087 · Cited by 346
Pharmaceutical metabolites in the environment: Analytical challenges and ecological risks
Celiz, M. D., Tso, J., & Aga, D. S. (2010) · Environmental Toxicology and Chemistry · doi:10.1897/09-173.1 · Cited by 339
Johnson, A. C., & Williams, R. J. (2004) · Environmental Science & Technology · doi:10.1021/es035342u · Cited by 322
Swartz, C. H., Reddy, S., Benotti, M. J., Yin, H., Barber, L. B., Brownawell, B. J., & Rudel, R. A. (2006) · Environmental Science & Technology · doi:10.1021/es052595+ · Cited by 252
Direct and Indirect Responses of a Freshwater Food Web to a Potent Synthetic Oestrogen
Kidd, K. A., Paterson, M. J., Rennie, M. D., Podemski, C. L., Findlay, D. L., Blanchfield, P. J., & Liber, K. (2014) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0578 · Cited by 189
Accurate Removal of Toxic Organic Pollutants from Complex Water Matrices
Cai, J., Niu, B., Xie, Q., Lu, N., Huang, S., Zhao, G., & Zhao, J. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.1c07824 · Cited by 189
Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice
Ryan, B. C., & Vandenbergh, J. G. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.01.007 · Cited by 180
Daughton, C. G. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.03.109 · Cited by 177
Why Endocrine Disrupting Chemicals (EDCs) Challenge Traditional Risk Assessment and How to Respond
Futran Fuhrman, V., Tal, A., & Arnon, S. (2015) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2014.12.012 · Cited by 152
Are Oral Contraceptives a Significant Contributor to the Estrogenicity of Drinking Water?
Wise, A., O’Brien, K., & Woodruff, T. (2011) · Environmental Science & Technology · doi:10.1021/es1014482 · Cited by 150
Metadata
- Authors
- Routledge, E. J., Sheahan, D., Desbrow, C., Brighty, G. C., Waldock, M., & Sumpter, J. P.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 1998-04-17
- Volume
- 32
- Issue
- 11
- Pages
- 1559-1565
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W1988757070
- Cited by
- 995
- References
- 0
- FWCI
- 33.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
