The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Inhibition Assay of Biomolecules based on Fluorescence Resonance Energy Transfer (FRET) between Quantum Dots and Gold Nanoparticles
Abstract
An inhibition assay method was developed based on the modulation in the FRET efficiency between quantum dots (QDs) and gold nanoparticles (AuNPs) in the presence of the molecules which inhibit the interactions between QD- and AuNP-conjugated biomolecules. For the functionalization, AuNPs were first stabilized by chemisorption of n-alkanethiols and then capped with the first generation polyamidoamine (G1 PAMAM) dendrimers. By employing a streptavidin-biotin couple as a model system, avidin was quantitatively analyzed as an inhibitor by sensing the change in photoluminescence (PL) quenching of SA-QDs by biotin-AuNPs. The detection limit for avidin was about 10 nM. It is anticipated that the PL quenching-based sensing system can be used for the quantitative analysis and high throughput screening of molecules which inhibit the specific biomolecular interactions.
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The use of nanocrystals in biological detection
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Dendrimers and Other Dendritic Polymers
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Fluorescence Resonance Energy Transfer Between Quantum Dot Donors and Dye-Labeled Protein Acceptors
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Fluorescence Quenching of Dye Molecules near Gold Nanoparticles: Radiative and Nonradiative Effects
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Cited by
Gold Nanoparticles in Chemical and Biological Sensing
Saha, K., Agasti, S. S., Kim, C., Li, X., & Rotello, V. M. (2012) · Chemical Reviews · doi:10.1021/cr2001178 · Cited by 4,620
Applications of Nanoparticles in Biology
De, M., Ghosh, P. S., & Rotello, V. M. (2008) · Advanced Materials · doi:10.1002/adma.200703183 · Cited by 1,547
Gold Nanomaterials at Work in Biomedicine
Yang, X., Yang, M., Pang, B., Vara, M., & Xia, Y. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00193 · Cited by 1,162
Plasmon-enhanced optical sensors: a review
Li, M., Cushing, S. K., & Wu, N. (2015) · The Analyst · doi:10.1039/c4an01079e · Cited by 1,011
Toxicity and Environmental Risks of Nanomaterials: Challenges and Future Needs
RAY, P. C., YU, H., & FU, P. P. (2009) · Journal of Environmental Science and Health, Part C · doi:10.1080/10590500802708267 · Cited by 936
Metadata
- Authors
- Oh, E., Hong, M.-Y., Lee, D., Nam, S.-H., Yoon, H. C., & Kim, H.-S.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-02-19
- Volume
- 127
- Issue
- 10
- Pages
- 3270-3271
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2061321072
- Cited by
- 512
- References
- 21
- FWCI
- 9.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Oh, E., Hong, M.-Y., Lee, D., Nam, S.-H., Yoon, H. C., & Kim, H.-S. (2005). Inhibition Assay of Biomolecules based on Fluorescence Resonance Energy Transfer (FRET) between Quantum Dots and Gold Nanoparticles. Journal of the American Chemical Society. https://doi.org/10.1021/ja0433323
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