The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Ultrasmall Reduced Graphene Oxide with High Near-Infrared Absorbance for Photothermal Therapy
Abstract
We developed nanosized, reduced graphene oxide (nano-rGO) sheets with high near-infrared (NIR) light absorbance and biocompatibility for potential photothermal therapy. The single-layered nano-rGO sheets were ∼20 nm in average lateral dimension, functionalized noncovalently by amphiphilic PEGylated polymer chains to render stability in biological solutions and exhibited 6-fold higher NIR absorption than nonreduced, covalently PEGylated nano-GO. Attaching a targeting peptide bearing the Arg-Gly-Asp (RGD) motif to nano-rGO afforded selective cellular uptake in U87MG cancer cells and highly effective photoablation of cells in vitro. In the absence of any NIR irradiation, nano-rGO exhibited little toxicity in vitro at concentrations well above the doses needed for photothermal heating. This work established nano-rGO as a novel photothermal agent due to its small size, high photothermal efficiency, and low cost as compared to other NIR photothermal agents including gold nanomaterials and carbon nanotubes.
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Cites
Ni(OH) 2 Nanoplates Grown on Graphene as Advanced Electrochemical Pseudocapacitor Materials
Wang, H., Casalongue, H. S., Liang, Y., & Dai, H. (2010) · Journal of the American Chemical Society · doi:10.1021/ja102267j · Cited by 2,042
Self-citationA route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice
Welsher, K., Liu, Z., Sherlock, S. P., Robinson, J. T., Chen, Z., Daranciang, D., & Dai, H. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.294 · Cited by 1,287
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Cited by
Smith, A. T., LaChance, A. M., Zeng, S., Liu, B., & Sun, L. (2019) · Nano Materials Science · doi:10.1016/j.nanoms.2019.02.004 · Cited by 1,643
Two-Dimensional Ultrathin MXene Ceramic Nanosheets for Photothermal Conversion
Lin, H., Wang, X., Yu, L., Chen, Y., & Shi, J. (2017) · Nano Letters · doi:10.1021/acs.nanolett.6b04339 · Cited by 1,314
Nanotoxicity of Graphene and Graphene Oxide
Seabra, A. B., Paula, A. J., de Lima, R., Alves, O. L., & Durán, N. (2014) · Chemical Research in Toxicology · doi:10.1021/tx400385x · Cited by 893
Graphene-based smart materials
Yu, X., Cheng, H., Zhang, M., Zhao, Y., Qu, L., & Shi, G. (2017) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.46 · Cited by 796
Han, L., Lu, X., Wang, M., Gan, D., Deng, W., Wang, K., Fang, L., Liu, K., Chan, C. W., Tang, Y., et al. (2017) · Small · doi:10.1002/smll.201601916 · Cited by 699
Metadata
- Authors
- Robinson, J. T., Tabakman, S. M., Liang, Y., Wang, H., Sanchez Casalongue, H., Vinh, D., & Dai, H.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-04-08
- Volume
- 133
- Issue
- 17
- Pages
- 6825-6831
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2326443463
- Cited by
- 2,099
- References
- 2
- FWCI
- 63.08
- Type
- journal article
- Language
- en
- Open access
- closed
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