A mussel-inspired conductive, self-adhesive, and self-healable tough hydrogel as cell stimulators and implantable bioelectronics
Abstract
A graphene oxide conductive hydrogel is reported that simultaneously possesses high toughness, self-healability, and self-adhesiveness. Inspired by the adhesion behaviors of mussels, our conductive hydrogel shows self-adhesiveness on various surfaces and soft tissues. The hydrogel can be used as self-adhesive bioelectronics, such as electrical stimulators to regulate cell activity and implantable electrodes for recording in vivo signals.
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The introduction of noncovalent interactions into the gel network not only enhances the structural integrity of the hydrogel networks but also endows these materials with additional characteristics, such as self-healing capabilities.
“The introduction of noncovalent interactions into the gel network not only enhances the structural integrity of the hydrogel networks but also endows these materials with additional characteristics, such as self-healing capabilities [72].”
From Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications (2024) · cites this paper as [72]
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Self-citationMultifunctional Skin‐Inspired Flexible Sensor Systems for Wearable Electronics
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Mussel-Inspired Injectable Adhesive Hydrogels for Biomedical Applications
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“The introduction of noncovalent interactions into the gel network not only enhances the structural integrity of the hydrogel networks but also endows these materials with additional characteristics, such as self-healing capabilities [72].”
BackgroundA handheld bioprinter for multi-material printing of complex constructs
Pagan, E., Stefanek, E., Seyfoori, A., Razzaghi, M., Chehri, B., Mousavi, A., Arnaldi, P., Ajji, Z., Dartora, D. R., Dabiri, S. M. H., et al. (2023) · Biofabrication · doi:10.1088/1758-5090/acc42c · Cited by 43 · see citing works
- Authors
- Han, L., Lu, X., Wang, M., Gan, D., Deng, W., Wang, K., Fang, L., Liu, K., Chan, C. W., Tang, Y., Weng, L., & Yuan, H.
- Affiliations
- Southwest Jiaotong University (CN)
- Sichuan University (CN)
- South China University of Technology (CN)
- Chinese University of Hong Kong (HK)
- Flinders University (AU)
- Hong Kong University of Science and Technology (HK)
- Corresponding author
- Lu, Xiong
- ORCID
- Venue
- Small
- Publisher
- Wiley
- Published
- 2016-10-25
- Volume
- 13
- Issue
- 2
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2534624125
- Cited by
- 699
- References
- 4
- Citations by year
- 2026: 19 · 2025: 55 · 2024: 76 · 2023: 94 · 2022: 90 · 2021: 95 · 2020: 114 · 2019: 95 · 2018: 46 · 2017: 15
- FWCI
- 25.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Small (publishedVersion)
- PubMed (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- National Natural Science Foundation of China (81671824)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Polymers and Plastics › Conducting polymers and applications
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Keywords
- mussel-inspired adhesion, conductive hydrogels, graphene oxide, self-healing hydrogels, self-adhesion, tough hydrogels, cell stimulation, implanted electrodes, bioelectronics, soft tissue adhesion
- MeSH terms
- Polyacrylamides, Acrylic Resins, Adhesives, Animals, Electric Conductivity, Electrodes, Electronics, Graphite, Indoles, Oxidation-Reduction, Polymers, Rabbits, Prostheses and Implants, Hydrogel, Polyethylene Glycol Dimethacrylate, Bivalvia, Mesenchymal Stem Cells
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