The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides
Open accessAbstract
A hydrogen peroxide (H2O2)-activated cell-penetrating peptide was developed through incorporation of a boronic acid-containing cleavable linker between polycationic cell-penetrating peptide and polyanionic fragments. Fluorescence labeling of the two ends of the molecule enabled monitoring its reaction with H2O2 through release of the highly adhesive cell-penetrating peptide and disruption of fluorescence resonance energy transfer. The H2O2 sensor selectively reacts with endogenous H2O2 in cell culture to monitor the oxidative burst of promyelocytes and in vivo to image lung inflammation. Targeting H2O2 has potential applications in imaging and therapy of diseases related to oxidative stress.
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Cites
Neurodegenerative diseases and oxidative stress
Barnham, K. J., Masters, C. L., & Bush, A. I. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1330 · Cited by 3,683
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
D'Autréaux, B., & Toledano, M. B. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2256 · Cited by 3,642
Reactive oxygen species have a causal role in multiple forms of insulin resistance
Houstis, N., Rosen, E. D., & Lander, E. S. (2006) · Nature · doi:10.1038/nature04634 · Cited by 2,525
Hydrogen peroxide mediates amyloid β protein toxicity
Behl, C. (1994) · Cell · doi:10.1016/0092-8674(94)90131-7 · Cited by 2,074
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide
Winterbourn, C. C., & Metodiewa, D. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00051-9 · Cited by 799
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Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging
Liu, H.-W., Chen, L., Xu, C., Li, Z., Zhang, H., Zhang, X.-B., & Tan, W. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00862g · Cited by 948
Tumor penetrating peptides for improved drug delivery
Ruoslahti, E. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.03.008 · Cited by 459
Mao, D., Hu, F., Kenry, Ji, S., Wu, W., Ding, D., Kong, D., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201706831 · Cited by 334
Liu, Q., Wang, J., & Boyd, B. J. (2015) · Talanta · doi:10.1016/j.talanta.2014.12.020 · Cited by 277
An Activatable Prodrug for the Treatment of Metastatic Tumors
Kim, E.-J., Bhuniya, S., Lee, H., Kim, H. M., Cheong, C., Maiti, S., Hong, K. S., & Kim, J. S. (2014) · Journal of the American Chemical Society · doi:10.1021/ja5077684 · Cited by 268
Recent advances in carbon nanofibers and their applications – A review
Yadav, D., Amini, F., & Ehrmann, A. (2020) · European Polymer Journal · doi:10.1016/j.eurpolymj.2020.109963 · Cited by 265
Ding, Y., Yang, B., Liu, H., Liu, Z., Zhang, X., Zheng, X., & Liu, Q. (2018) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2017.12.115 · Cited by 264
Leveraging Physiology for Precision Drug Delivery
Sun, W., Hu, Q., Ji, W., Wright, G., & Gu, Z. (2017) · Physiological Reviews · doi:10.1152/physrev.00015.2016 · Cited by 169
Metadata
- Authors
- Weinstain, R., Savariar, E. N., Felsen, C. N., & Tsien, R. Y.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-01-08
- Volume
- 136
- Issue
- 3
- Pages
- 874-877
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2161146618
- Cited by
- 239
- References
- 5
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
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