Neurodegenerative diseases and oxidative stress

Free radicals in biology and medicine

Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178 · see citing works

Free Radicals in Biology and Medicine

Halliwell, B., & Gutteridge, J. M. C. (2015) · doi:10.1093/acprof:oso/9780198717478.001.0001 · Cited by 8,990 · see citing works

α-Synuclein in Lewy bodies

Spillantini, M. G., Schmidt, M. L., Lee, V. M.-Y., Trojanowski, J. Q., Jakes, R., & Goedert, M. (1997) · Nature · doi:10.1038/42166 · Cited by 8,382 · see citing works

Parkinson's Disease

Dauer, W., & Przedborski, S. (2003) · Neuron · doi:10.1016/s0896-6273(03)00568-3 · Cited by 5,469 · see citing works

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

Glenner, G. G., & Wong, C. W. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(84)80190-4 · Cited by 5,404 · see citing works

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K., & Müller-Hill, B. (1987) · Nature · doi:10.1038/325733a0 · Cited by 4,619 · see citing works

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., & Beyreuther, K. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.12.4245 · Cited by 4,431 · see citing works

Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

Gurney, M. E., Pu, H., Chiu, A. Y., Dal Canto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., Deng, H.-X., et al. (1994) · Science · doi:10.1126/science.8209258 · Cited by 4,143 · see citing works

Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

Campuzano, V., Montermini, L., Moltò, M. D., Pianese, L., Cossée, M., Cavalcanti, F., Monros, E., Rodius, F., Duclos, F., Monticelli, A., et al. (1996) · Science · doi:10.1126/science.271.5254.1423 · Cited by 2,786 · see citing works

A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease

Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C. W., Pfeiffer, E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704243361704 · Cited by 2,380 · see citing works

A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis

Bensimon, G., Lacomblez, L., & Meininger, V. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403033300901 · Cited by 2,239 · see citing works

Copper, iron and zinc in Alzheimer's disease senile plaques

Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., & Markesbery, W. R. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00092-6 · Cited by 2,120 · see citing works

Hydrogen peroxide mediates amyloid β protein toxicity

Behl, C. (1994) · Cell · doi:10.1016/0092-8674(94)90131-7 · Cited by 2,074 · see citing works

Memantine in Moderate-to-Severe Alzheimer's Disease

Reisberg, B., Doody, R., Stöffler, A., Schmitt, F., Ferris, S., & Möbius, H. J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa013128 · Cited by 2,043 · see citing works

Undetectable Intracellular Free Copper: The Requirement of a Copper Chaperone for Superoxide Dismutase

Rae, T., Schmidt, P. J., Pufahl, R. A., Culotta, V., & O’Halloran, T. V. (1999) · Science · doi:10.1126/science.284.5415.805 · Cited by 1,628 · see citing works

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Cherny, R. A., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y.-S., et al. (2001) · Neuron · doi:10.1016/s0896-6273(01)00317-8 · Cited by 1,447 · see citing works

Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease

Dexter, D. T., Carter, C. J., Wells, F. R., Javoy-Agid, F., Agid, Y., Lees, A. J., Jenner, P. G., & MARSDEN, C. D. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09133.x · Cited by 1,397 · see citing works

Amyloid, the presenilins and Alzheimer’s disease

Hardy, J. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)01030-2 · Cited by 1,370 · see citing works

Oxidants as Stimulators of Signal Transduction

Suzuki, Y. J., Forman, H. J., & Sevanian, A. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00275-4 · Cited by 1,360 · see citing works

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

Smith, M. A., Harris, P. L. R., Sayre, L. M., & Perry, G. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.18.9866 · Cited by 1,357 · see citing works

The metallobiology of Alzheimer's disease

Bush, A. I. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00067-5 · Cited by 1,315 · see citing works

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

Hirsch, E., Graybiel, A. M., & Agid, Y. A. (1988) · Nature · doi:10.1038/334345a0 · Cited by 1,301 · cited 1× · see citing works

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Bruijn, L. I., Houseweart, M. K., Kato, S., Anderson, K. L., Anderson, S., Ohama, E., Reaume, A. G., Scott, R. W., & Cleveland, D. W. (1998) · Science · doi:10.1126/science.281.5384.1851 · Cited by 1,231 · see citing works

Effects of Tocopherol and Deprenyl on the Progression of Disability in Early Parkinson's Disease

The Parkinson Study Group (1993) · New England Journal of Medicine · doi:10.1056/nejm199301213280305 · Cited by 1,222 · see citing works

Hydrogen peroxide signalling

Neill, S. J. (2002) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(02)00282-0 · Cited by 1,210 · see citing works

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction

Huang, X., Atwood, C., Hartshorn, M. A., Multhaup, G., Goldstein, L. E., Scarpa, R. C., Cuajungco, M. P., Gray, D. N., Lim, J. T., Moir, R. D., et al. (1999) · Biochemistry · doi:10.1021/bi990438f · Cited by 1,107 · see citing works

Metal-triggered Structural Transformations, Aggregation, and Fibrillation of Human α-Synuclein

Uversky, V. N., Li, J., & Fink, A. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105343200 · Cited by 1,103 · see citing works

Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis

Atwood, C. S., Moir, R. D., Huang, X., Scarpa, R. C., Bacarra, N. M. E., Romano, D. M., Hartshorn, M. A., Tanzi, R. E., & Bush, A. I. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.21.12817 · Cited by 1,009 · see citing works

Metal-Protein Attenuation With Iodochlorhydroxyquin (Clioquinol) Targeting Aβ Amyloid Deposition and Toxicity in Alzheimer Disease: A Pilot Phase 2 Clinical Trial

Ritchie, C. W., Bush, A. I., Mackinnon, A., Macfarlane, S., Mastwyk, M., MacGregor, L., Kiers, L., Cherny, R., Li, Q.-X., Tammer, A., et al. (2003) · Archives of Neurology · doi:10.1001/archneur.60.12.1685 · Cited by 988 · see citing works

Calcium dyshomeostasis and intracellular signalling in alzheimer's disease

LaFerla, F. M. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn960 · Cited by 970 · see citing works

Calcium and oxidative stress: from cell signaling to cell death

Ermak, G., & Davies, K. J. A. (2002) · Molecular Immunology · doi:10.1016/s0161-5890(01)00108-0 · Cited by 874 · see citing works

The Role of Copper in Neurodegenerative Disease

Waggoner, D., Bartnikas, T. B., & Gitlin, J. D. (1999) · Neurobiology of Disease · doi:10.1006/nbdi.1999.0250 · Cited by 858 · see citing works

The Copper Chaperone for Superoxide Dismutase

Culotta, V., Klomp, L. W. J., Strain, J. J., Casareno, R. L. B., Krems, B., & Gitlin, J. D. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.38.23469 · Cited by 851 · see citing works

Oxidative DNA Damage in the Parkinsonian Brain: An Apparent Selective Increase in 8‐Hydroxyguanine Levels in Substantia Nigra

Alam, Z. I., Jenner, A., Daniel, S. E., Lees, A. J., Cairns, N., Marsden, C. D., Jenner, P., & Halliwell, B. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69031196.x · Cited by 845 · see citing works

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

Levin, V. A. (1980) · Journal of Medicinal Chemistry · doi:10.1021/jm00180a022 · Cited by 815 · see citing works

Intramuscular desferrioxamine in patients with Alzheimer's disease

MCLACHLAN, D. (1991) · The Lancet · doi:10.1016/0140-6736(91)92978-b · Cited by 764 · see citing works

Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity

Huang, X., Cuajungco, M. P., Atwood, C. S., Hartshorn, M. A., Tyndall, J. D. A., Hanson, G. R., Stokes, K. C., Leopold, M., Multhaup, G., Goldstein, L. E., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.52.37111 · Cited by 762 · see citing works

Free Radical Pathways in CNS Injury

LEWÉN, A., MATZ, P., & CHAN, P. H. (2000) · Journal of Neurotrauma · doi:10.1089/neu.2000.17.871 · Cited by 759 · see citing works

Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

Xu, J., Kao, S., Lee, F. J. S., Song, W., Jin, L., & Yankner, B. A. (2002) · Nature Medicine · doi:10.1038/nm0602-600 · Cited by 757 · see citing works

Metals and neuroscience

Bush, A. (2000) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(99)00073-3 · Cited by 731 · see citing works

Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis

Wiedau‐Pazos, M., Goto, J. J., Rabizadeh, S., Gralla, E. B., Roe, J. A., Lee, M. K., Valentine, J. S., & Bredesen, D. E. (1996) · Science · doi:10.1126/science.271.5248.515 · Cited by 720 · see citing works

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death1

Allanbutterfield, D., Castegna, A., Lauderback, C. M., & Drake, J. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00340-2 · Cited by 715 · see citing works

Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits

Curtain, C. C., Ali, F. E. A., Volitakis, I., Cherny, R. A., Norton, R. S., Beyreuther, K. T., Barrow, C. J., Masters, C. L., Bush, A. I., & Barnham, K. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100175200 · Cited by 653 · see citing works

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides: Identification of an Attomolar‐Affinity Copper Binding Site on Amyloid β1‐42

Atwood, C. S., Scarpa, R. C., Huang, X., Moir, R. D., Jones, W. D., Fairlie, D. P., Tanzi, R. E., & Bush, A. I. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0751219.x · Cited by 641 · see citing works

Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo

Kaur, D., Yantiri, F., Rajagopalan, S., Kumar, J., Mo, J. Q., Boonplueang, R., Viswanath, V., Jacobs, R., Yang, L., Beal, M. F., et al. (2003) · Neuron · doi:10.1016/s0896-6273(03)00126-0 · Cited by 620 · see citing works

Chemistry and Biochemistry of Oxidative Stress in Neurodegenerative Disease

Sayre, L. M., Smith, M. A., & Perry, G. L. (2001) · Current Medicinal Chemistry · doi:10.2174/0929867013372922 · Cited by 614 · see citing works

A Role for α-Synuclein in the Regulation of Dopamine Biosynthesis

Perez, R. G., Waymire, J. C., Lin, E., Liu, J. J., Guo, F., & Zigmond, M. J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-08-03090.2002 · Cited by 598 · see citing works

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

Estévez, A. G., Crow, J. P., Sampson, J. B., Reiter, C., Zhuang, Y., Richardson, G. J., Tarpey, M. M., Barbeito, L., & Beckman, J. S. (1999) · Science · doi:10.1126/science.286.5449.2498 · Cited by 596 · see citing works

Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid

Opazo, C., Huang, X., Cherny, R. A., Moir, R. D., Roher, A. E., White, A. R., Cappai, R., Masters, C. L., Tanzi, R. E., Inestrosa, N. C., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m206428200 · Cited by 580 · see citing works

Metal Binding and Oxidation of Amyloid-β within Isolated Senile Plaque Cores: Raman Microscopic Evidence

Dong, J., Atwood, C., Anderson, V. E., Siedlak, S. L., Smith, M. A., Perry, G. L., & CAREY, P. R. (2003) · Biochemistry · doi:10.1021/bi0272151 · Cited by 560 · see citing works

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

Mark, R. J., Hensley, K., Butterfield, D. A., & Mattson, M. P. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06239.1995 · Cited by 553 · see citing works

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

Rogers, J. T., Randall, J. D., Cahill, C. M., Eder, P. S., Huang, X., Gunshin, H., Leiter, L., McPhee, J., Sarang, S. S., Utsuki, T., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207435200 · Cited by 551 · see citing works

Misfolded CuZnSOD and amyotrophic lateral sclerosis

Valentine, J. S., & Hart, P. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0730423100 · Cited by 546 · see citing works

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

Sayre, L. M., Perry, G. L., Harris, P. L. R., Liu, Y. A., Schubert, K. A., & Smith, M. A. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0740270.x · Cited by 538 · see citing works

Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal Depletion

Cherny, R. A., Legg, J. T., McLean, C. A., Fairlie, D. P., Huang, X., Atwood, C. S., Beyreuther, K., Tanzi, R. E., Masters, C. L., & Bush, A. I. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23223 · Cited by 482 · see citing works

Increased Nuclear DNA Oxidation in the Brain in Alzheimer's Disease

Gabbita, S. P., Lovell, M. A., & Markesbery, W. R. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.71052034.x · Cited by 479 · see citing works

Excitotoxic and Excitoprotective Mechanisms: Abundant Targets for the Prevention and Treatment of Neurodegenerative Disorders

Mattson, M. P. (2003) · NeuroMolecular Medicine · doi:10.1385/nmm:3:2:65 · Cited by 475 · see citing works

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

Sulzer, D. L., Bogulavsky, J. J., Larsen, K. E., Behr, G. G., Karatekin, E., Kleinman, M. H., Turro, N. J., Krantz, D. E., Edwards, R. H., Greene, L. A., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.22.11869 · Cited by 460 · see citing works

Neuronal and glial calcium signaling in Alzheimer’s disease

Mattson, M. P., & Chan, S. L. (2003) · Cell Calcium · doi:10.1016/s0143-4160(03)00128-3 · Cited by 454 · see citing works

Impairment of Glucose and Glutamate Transport and Induction of Mitochondrial Oxidative Stress and Dysfunction in Synaptosomes by Amyloid β‐Peptide: Role of the Lipid Peroxidation Product 4‐Hydroxynonenal

Keller, J. N., Pang, Z., Geddes, J. W., Begley, J. G., Germeyer, A., Waeg, G., & Mattson, M. P. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69010273.x · Cited by 439 · see citing works

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

Lee, J., Cole, T. B., Palmiter, R. D., Suh, S. W., & Koh, J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092034699 · Cited by 432 · see citing works

ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models

Price, D. L., Tanzi, R. E., Borchelt, D. R., & Sisodia, S. S. (1998) · Annual Review of Genetics · doi:10.1146/annurev.genet.32.1.461 · Cited by 406 · see citing works

Evidence that the β-Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Aβ by Zinc

Cuajungco, M. P., Goldstein, L. E., Nunomura, A., Smith, M. A., Lim, J. T., Atwood, C., Huang, X., Farrag, Y. W., Perry, G. L., & Bush, A. I. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.c000165200 · Cited by 392 · see citing works

Protein modification by the lipid peroxidation product 4‐hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

Pedersen, W. A., Fu, W., Keller, J. N., Markesbery, W. R., Appel, S. H., Smith, R. G., Kasarskis, E. J., & Mattson, M. P. (1998) · Annals of Neurology · doi:10.1002/ana.410440518 · Cited by 391 · see citing works

The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

Wong, A. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.3.425 · Cited by 374 · see citing works

The presenilins and Alzheimer's disease

Hutton, M. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.10.1639 · Cited by 368 · see citing works

Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease.

Pappolla, M. A., Omar, R. A., Kim, K. S., & Robakis, N. K. R. K. (1992) · PubMed Central · Cited by 363 · see citing works

Overexpression of Alzheimer's Disease Amyloid-β Opposes the Age-dependent Elevations of Brain Copper and Iron

Maynard, C. J., Cappai, R., Volitakis, I., Cherny, R. A., White, A. R., Beyreuther, K. T., Masters, C. L., Bush, A. I., & Li, Q. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204379200 · Cited by 352 · see citing works

Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line

Lotharius, J., Barg, S., Wiekop, P., Lundberg, C., Raymon, H. K., & Brundin, P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205518200 · Cited by 349 · see citing works

Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study

Rustin, P., von Kleist-Retzow, J., Chantrel-Groussard, K., Sidi, D., Münnich, A., & Rötig, A. (1999) · The Lancet · doi:10.1016/s0140-6736(99)01341-0 · Cited by 348 · see citing works

Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia

Bradley, J. L. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.2.275 · Cited by 339 · see citing works

Copper(II)-induced self-oligomerization of α-synuclein

Paik, S. R., Shin, H.-J., Lee, J., Chang, C., & Kim, J. (1999) · Biochemical Journal · doi:10.1042/bj3400821 · Cited by 332 · see citing works

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice

Bayer, T. A., Schäfer, S., Simons, A., Kemmling, A., Kamer, T., Tepest, R., Eckert, A., Schüssel, K., Eikenberg, O., Sturchler, C., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2332818100 · Cited by 325 · see citing works

Zinc-induced Alzheimer's Aβ1–40 Aggregation Is Mediated by Conformational Factors

Huang, X., Atwood, C., Moir, R. D., Hartshorn, M. A., Vonsattel, J., Tanzi, R. E., & Bush, A. I. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.42.26464 · Cited by 313 · see citing works

Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β

Atwood, C., Obrenovich, M. E., Liu, T., Chan, H., Perry, G. L., Smith, M. A., & Martins, R. N. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00174-7 · Cited by 292 · see citing works

The Pathogenesis of Alzheimer Disease: An Alternative to the Amyloid Hypothesis

Terry, R. D. (1996) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199655100-00001 · Cited by 291 · see citing works

Iron‐Melanin Interaction and Lipid Peroxidation: Implications for Parkinson's Disease

Ben‐Shachar, D., Riederer, P. F., & Youdim, M. B. H. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb06358.x · Cited by 287 · see citing works

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

White, A. R., Reyes, R., Mercer, J. F. B., Camakaris, J., Zheng, H., Bush, A. I., Multhaup, G., Beyreuther, K. T., Masters, C. L., & Cappai, R. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01861-2 · Cited by 283 · see citing works

Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain

Barnham, K. J., McKinstry, W. J., Multhaup, G., Galatis, D., Morton, C. J., Curtain, C. C., Williamson, N. A., White, A. R., Hinds, M. G., Norton, R. S., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300629200 · Cited by 274 · see citing works

Vitamin E and Alzheimer disease: the basis for additional clinical trials

Grundman, M. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.2.630s · Cited by 267 · see citing works

Mutant SOD1 causes motor neuron disease independent of copper chaperone–mediated copper loading

Subramaniam, J. R., Lyons, W. E., Liu, J., Bartnikas, T. B., Rothstein, J. D., Price, D. L., Cleveland, D. W., Gitlin, J. D., & Wong, P. C. (2002) · Nature Neuroscience · doi:10.1038/nn823 · Cited by 267 · see citing works

Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

Lotharius, J. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.20.2395 · Cited by 267 · see citing works

Antioxidants as treatment for neurodegenerative disorders

Moosmann, B., & Behl, C. (2002) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.11.10.1407 · Cited by 253 · see citing works

Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia

HAUSSE, A., Aggoun, Y., Bonnet, D., Sidi, D., Münnich, A., Rötig, A., & Rustin, P. (2002) · Heart · doi:10.1136/heart.87.4.346 · Cited by 251 · see citing works

Elevation of serum copper levels in Alzheimer’s disease

Squitti, R., Lupoi, D., Pasqualetti, P., Forno, G. D., Vernieri, F., Chiovenda, P., Rossi, L. C., Cortesi, M., Cassetta, E., & Rossini, P. M. (2002) · Neurology · doi:10.1212/wnl.59.8.1153 · Cited by 236 · see citing works

Increased Cerebral Glucose‐6‐Phosphate Dehydrogenase Activity in Alzheimer's Disease May Reflect Oxidative Stress

Martins, R. N., Harper, C. G., Stokes, G. B., & Masters, C. L. (1986) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1986.tb00615.x · Cited by 234 · see citing works

Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease

Faucheux, B. A., Martin, M., Beaumont, C., Hauw, J., Agid, Y., & Hirsch, E. C. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01923.x · Cited by 229 · see citing works

Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease.

Basun, H., Forssell, L. G., Wetterberg, L., & Winblad, B. G. (1991) · PubMed · Cited by 228 · see citing works

Cytochemical Demonstration of Oxidative Damage in Alzheimer Disease by Immunochemical Enhancement of the Carbonyl Reaction with 2,4-Dinitrophenylhydrazine

Smith, M. A., Sayre, L. M., Anderson, V. E., Harris, P. L. R., Beal, M. F., Kowall, N. W., & Perry, G. L. (1998) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215549804600605 · Cited by 222 · see citing works

Adult-derived neural precursors transplanted into multiple regions in the adult brain

Herrera, D. G., García‐Verdugo, J. M., & Álvarez-Buylla, A. (1999) · Annals of Neurology · doi:10.1002/1531-8249(199912)46:6 · Cited by 204 · see citing works

H2o2 and 4-hydroxynonenal mediate amyloid β-induced neuronal apoptosis by activating jnks and p38mapk

Tamagno, E., Robino, G., Obbili, A., Bardini, P., Aragno, M., Parola, M., & Danni, O. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(02)00059-6 · Cited by 201 · see citing works

In vivo reduction of amyloid-β by a mutant copper transporter

Phinney, A. L., Drisaldi, B., Schmidt, S. D., Lugowski, S. J., Coronado, V. A., Liang, Y., Horne, P., Yang, J., Sekoulidis, J., Coomaraswamy, J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2332851100 · Cited by 201 · see citing works

Metal Ions, pH, and Cholesterol Regulate the Interactions of Alzheimer's Disease Amyloid-β Peptide with Membrane Lipid

Curtain, C. C., Ali, F. E. A., Smith, D. G., Bush, A. I., Masters, C. L., & Barnham, K. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m205455200 · Cited by 200 · see citing works

Memantine: update on the current evidence

bius, H. J. R. M. (2003) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.939 · Cited by 198 · see citing works

Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

Zemlan, F. P., Thienhaus, O. J., & Bosmann, H. B. (1989) · Brain Research · doi:10.1016/0006-8993(89)91550-3 · Cited by 195 · see citing works

Mutant Superoxide Dismutase-1-Linked Familial Amyotrophic Lateral Sclerosis: Molecular Mechanisms of Neuronal Death and Protection

Ghadge, G. D., Lee, J. P., Bindokas, V. P., Jordán, J., Ma, L., Miller, R. J., & Roos, R. P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-22-08756.1997 · Cited by 195 · see citing works

Neurotoxic, Redox-competent Alzheimer's β-Amyloid Is Released from Lipid Membrane by Methionine Oxidation

Barnham, K. J., Ciccotosto, G. D., Tickler, A. K., Ali, F. E. A., Smith, D. G., Williamson, N. A., Lam, Y.-H., Carrington, D., Tew, D. J., Kocak, G., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305494200 · Cited by 188 · see citing works

Role of Free Radicals and Metal Ions in the Pathogenesis of Alzheimer’s Disease

Atwood, C. S., Huang, X., Moir, R. D., Tanzi, R. E., & Bush, A. I. (2018) · Routledge eBooks · doi:10.1201/9780203747605-10 · Cited by 183 · see citing works

Iron-binding characteristics of neuromelanin of the human substantia nigra

Double, K. L., Gerlach, M., Schünemann, V., TRAUTWEIN, A. X., Zecca, L., Gallorini, M., Youdim, M. B. H., Riederer, P. F., & Ben‐Shachar, D. (2003) · Biochemical Pharmacology · doi:10.1016/s0006-2952(03)00293-4 · Cited by 182 · see citing works

The Copper Chelator d‐Penicillamine Delays Onset of Disease and Extends Survival in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

Hottinger, A. F., Fine, E. G., Gurney, M. E., Zurn, A. D., & Aebischer, P. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01511.x · Cited by 181 · see citing works

Certain Metals Trigger Fibrillation of Methionine-oxidized α-Synuclein

Yamin, G., Glaser, C. B., Uversky, V. N., & Fink, A. L. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303302200 · Cited by 178 · see citing works

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease

Selley, M. L. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(01)00327-x · Cited by 175 · see citing works

Copper inhibits β -amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion

Borchardt, T., Camakaris, J., Cappai, R., Masters, C. L., Beyreuther, K. T., & Multhaup, G. (1999) · Biochemical Journal · doi:10.1042/bj3440461 · Cited by 174 · see citing works

The structure of neuromelanin as studied by chemical degradative methods

Wakamatsu, K., Fujikawa, K., Zucca, F. A., Zecca, L., & Ito, S. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01917.x · Cited by 172 · see citing works

Loss of in Vitro Metal Ion Binding Specificity in Mutant Copper-Zinc Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis

Goto, J. J., Zhu, H., Sanchez, R. J., Nersissian, A. M., Gralla, E. B., Valentine, J. S., & Cabelli, D. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.2.1007 · Cited by 166 · see citing works

α-Synuclein immunopositive Parkinson's disease-related inclusion bodies in lower brain stem nuclei

Braak, E., Sandmann-Keil, D., Rüb, U., Gai, W., de Vos, R. A. I., Steur, E. N. H. J., Arai, K., & Braak, H. (2001) · Acta Neuropathologica · doi:10.1007/s004010000247 · Cited by 162 · see citing works

Idebenone treatment in Friedreich’s ataxia

Buyse, G., Mertens, L., Salvo, G. D., Matthijs, I., Weidemann, F., Eyskens, B., Goossens, W., Goemans, N., Sutherland, G. R., & Hove, J. L. K. V. (2003) · Neurology · doi:10.1212/01.wnl.0000068549.52812.0f · Cited by 161 · see citing works

Co‐ordinate transcriptional regulation of dopamine synthesis genes by α‐synuclein in human neuroblastoma cell lines

Baptista, M. J., O’Farrell, C., Daya, S., Ahmad, R., Miller, D. W., Hardy, J., Farrer, M. J., & Cookson, M. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01742.x · Cited by 151 · see citing works

Lipid peroxidation in neurodegeneration: new insights into Alzheimerʼs disease

Arlt, S., Beisiegel†, U., & Kontush, A. (2002) · Current Opinion in Lipidology · doi:10.1097/00041433-200206000-00009 · Cited by 151 · see citing works

Modulation of dopamine transporter function by α‐synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

Wersinger, C., Prou, D., Vernier, P., & Sidhu, A. (2003) · The FASEB Journal · doi:10.1096/fj.03-0152fje · Cited by 144 · see citing works

Neuromelanin and Parkinson's disease.

MARSDEN, C. D. (1983) · PubMed · Cited by 143 · see citing works

Non-Cholinergic Strategies for Treating and Preventing Alzheimer??s Disease

Doraiswamy, P. M. (2002) · CNS Drugs · doi:10.2165/00023210-200216120-00003 · Cited by 142 · see citing works

Predicting Blood–Brain Barrier Partitioning of Organic Molecules Using Membrane–Interaction QSAR Analysis

Iyer, M., Mishra, R. K., Han, Y., & Hopfinger, A. J. (2002) · Pharmaceutical Research · doi:10.1023/a:1020792909928 · Cited by 140 · see citing works

Iron: A Pathological Mediator of Alzheimer Disease?

Bishop, G. M., Robinson, S. R., Liu, Q., Perry, G. L., Atwood, C., & Smith, M. A. (2002) · Developmental Neuroscience · doi:10.1159/000065696 · Cited by 138 · see citing works

Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures

Lovell, M. A., Xie, C., & Markesbery, W. R. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00346-4 · Cited by 127 · see citing works

Genetics of Parkinson's disease

Gasser, T. (2001) · Journal of Neurology · doi:10.1007/s004150170066 · Cited by 124 · see citing works

Genetics of Parkinson's disease.

Gasser, T. (2004) · Europe PMC (PubMed Central) · Cited by 111 · see citing works

Will caloric restriction and folate protect against AD and PD?

Mattson, M. P. (2003) · Neurology · doi:10.1212/01.wnl.0000042785.02850.11 · Cited by 111 · see citing works

Copper(2+) Binding to the Surface Residue Cysteine 111 of His46Arg Human Copper−Zinc Superoxide Dismutase, a Familial Amyotrophic Lateral Sclerosis Mutant

Liu, H., Zhu, H., Eggers, D. K., Nersissian, A. M., Faull, K. F., Goto, J. J., Ai, J., Sanders–Loehr, J., Gralla, E. B., & Valentine, J. S. (2000) · Biochemistry · doi:10.1021/bi000846f · Cited by 92 · see citing works

Development of potential iron chelators for the treatment of Friedreich’s ataxia: ligands that mobilize mitochondrial iron

Richardson, D. R., Mouralian, C., Ponka, P., & Becker, E. (2001) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(01)00041-2 · Cited by 91 · see citing works

Copper catalyzed oxidation of Alzheimer Abeta.

Atwood, C. S., Huang, X., Khatri, A., Scarpa, R. C., Kim, Y. S., Moir, R. D., Tanzi, R. E., Roher, A. E., & Bush, A. I. (2000) · PubMed · Cited by 89 · see citing works

The effect of aging on the mineral status of female mice

Morita, A., Kimura, M., & Itokawa, Y. (1994) · Biological Trace Element Research · doi:10.1007/bf02785387 · Cited by 81 · see citing works

On the function of neuromelanin

Smythies, J. (1996) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1996.0073 · Cited by 76 · see citing works

Oxidation of Aβ and Plaque Biogenesis in Alzheimer's Disease and Down Syndrome

Head, E., Garzon-Rodriguez, W., Johnson, J. K., Lott, I. T., Cotman, C. W., & Glabe, C. (2001) · Neurobiology of Disease · doi:10.1006/nbdi.2001.0431 · Cited by 75 · see citing works

Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease.

Gibson, G. (2002) · Free Radical Biology & Medicine · doi:10.1016/s0891-5849(02)00802-x · Cited by 74 · see citing works

Residual substantia nigra neuromelanin in Parkinson’s disease is cross-linked to α-synuclein

Fasano, M., Giraudo, S., Coha, S., Bergamasco, B., & Lopiano, L. (2003) · Neurochemistry International · doi:10.1016/s0197-0186(02)00161-4 · Cited by 70 · see citing works

Age-Related Changes in the Concentrations of Major and Trace Elements in the Brain of Rats and Mice

Takahashi, S., Takahashi, I., Sato, H., Kubota, Y., YOSHIDA, S., & Muramatsu, Y. (2001) · Biological Trace Element Research · doi:10.1385/bter:80:2:145 · Cited by 70 · see citing works

Investigation into the correlation between the structure of hydroxypyridinones and blood–brain barrier permeability

Habgood, M. D., Liu, Z. D., Saghaei, L., Khodr, H., Abbott, J., & Hider, R. C. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(99)00031-3 · Cited by 67 · see citing works

Lipid interaction of α‐synuclein during the metal‐catalyzed oxidation in the presence of Cu2+and H2O2

Lee, E., Lee, S., Lee, D., Kim, J., & Paik, S. R. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01612.x · Cited by 54 · see citing works

The neuromelanin of human substantia nigra: structure, synthesis and molecular behaviour

Zecca, L., Zucca, F. A., Costi, P., Tampellini, D., Gatti, A., Gerlach, M., Riederer, P. F., Fariello, R. G., Ito, S., Gallorini, M., et al. (2003) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-0643-3_8 · Cited by 52 · see citing works

Complexes of iron(III) with ligands of biological interest: dopamine and 8-hydroxyquinoline-5-sulphonic acid

Gérard, C., Chehhal, H., & Hugel, R. P. (1994) · Polyhedron · doi:10.1016/s0277-5387(00)84736-1 · Cited by 47 · see citing works

Metal ion chelation in neurodegenerative disorders

Angel, I., Bar, A., Horovitz, T., Taler, G., Krakovsky, M., Resnitsky, D., Rosenberg, G., Striem, S., Friedman, J. E., & Kozak, A. (2002) · Drug Development Research · doi:10.1002/ddr.10083 · Cited by 42 · see citing works

The hydroxyl radical scavenger Nicaraven inhibits glutamate release after spinal injury in rats

Yamamoto, K., Ishikawa, T., Sakabe, T., Taguchi, T., Kawai, S., & Maršala, M. (1998) · Neuroreport · doi:10.1097/00001756-199805110-00072 · Cited by 39 · see citing works

Functional dissection ofdrosophila capricious: its novel roles in neuronal pathfinding and selective synapse formation

Taniguchi, H., Shishido, E., Takeichi, M., & Nose, A. (2000) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(200001)42:1 · Cited by 35 · see citing works

Mining copper transport genes

Andrews, N. C. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.131192498 · Cited by 31 · see citing works

Is ALS caused by an altered oxidative activity of mutant superoxide dismutase?

Bush, A. I. (2002) · Nature Neuroscience · doi:10.1038/nn1002-919a · Cited by 31 · see citing works

Treatment of Parkinson's disease

Hely, M. A., Fung, V. S. C., & Morris, J. G. (2000) · Journal of Clinical Neuroscience · doi:10.1054/jocn.2000.0766 · Cited by 28 · see citing works

Treating the full spectrum of dementia with memantine

Winblad, B. G., & Jelić, V. (2003) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.937 · Cited by 26 · see citing works

Magnetic Resonance Studies of β-Amyloid Peptides

Lau, T., Barnham, K. J., Curtain, C. C., Masters, C. L., & Separovic, F. (2003) · Australian Journal of Chemistry · doi:10.1071/ch02268 · Cited by 17 · see citing works

Nitric Oxide and Peroxynitrite in Health and Disease

Pacher, P., Beckman, J. S., & Liaudet, L. (2007) · Physiological Reviews · doi:10.1152/physrev.00029.2006 · Cited by 6,390 · see citing works

Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications

Huang, Y., Ren, J., & Qu, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00672 · Cited by 3,565 · see citing works

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

Uttara, B., Singh, A., Zamboni, P., & Mahajan, R. (2009) · Current Neuropharmacology · doi:10.2174/157015909787602823 · Cited by 3,378 · see citing works

Oxidative stress and neurodegeneration: where are we now?

Halliwell, B. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03907.x · Cited by 2,614 · see citing works

Fluorescent Sensors for Measuring Metal Ions in Living Systems

Carter, K. P., Young, A. M., & Palmer, A. E. (2014) · Chemical Reviews · doi:10.1021/cr400546e · Cited by 2,443 · see citing works

Reactive Oxygen Species (ROS)-Based Nanomedicine

Yang, B., Chen, Y., & Shi, J. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00626 · Cited by 2,453 · see citing works

Luminescent Chemodosimeters for Bioimaging

Yang, Y., Zhao, Q., Feng, W., & Li, F. (2012) · Chemical Reviews · doi:10.1021/cr2004103 · Cited by 2,236 · see citing works

The Endocannabinoid System as an Emerging Target of Pharmacotherapy

Pacher, P., Bátkai, S., & Kunos, G. (2006) · Pharmacological Reviews · doi:10.1124/pr.58.3.2 · Cited by 2,077 · see citing works

Chemistry and biology of reactive oxygen species in signaling or stress responses

Dickinson, B. C., & Chang, C. J. (2011) · Nature Chemical Biology · doi:10.1038/nchembio.607 · Cited by 1,821 · see citing works

Iron, brain ageing and neurodegenerative disorders

Zecca, L., Youdim, M. B. H., Riederer, P., Connor, J. R., & Crichton, R. R. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1537 · Cited by 1,801 · see citing works

Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)

Gaggelli, E., Kozlowski, H., Valensin, D., & Valensin, G. (2006) · Chemical Reviews · doi:10.1021/cr040410w · Cited by 1,729 · see citing works

Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies

Bhatti, J. S., Bhatti, G. K., & Reddy, P. H. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.11.010 · Cited by 1,655 · see citing works

Encyclopedia of Inorganic and Bioinorganic Chemistry

Casini, A., Miller, J. J., Gomes, L. M. F., & Storr, T. (2011) · Wiley eBooks · doi:10.1002/9781119951438 · Cited by 1,596 · see citing works

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Sedgwick, A. C., Wu, L., Han, H., Bull, S. D., He, X., James, T. D., Sessler, J. L., Tang, B. Z., Tian, H., & Yoon, J. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00185e · Cited by 1,577 · see citing works

The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway

Baird, L., & Yamamoto, M. P. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00099-20 · Cited by 1,600 · see citing works

Functional Repression of cAMP Response Element in 6-Hydroxydopamine-treated Neuronal Cells*

Chalovich, E. M., Zhu, J.-H., Caltagarone, J., Bowser, R., & Chu, C. T. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602632200 · Cited by 108 · see citing works

The therapeutic potential of monoamine oxidase inhibitors

Youdim, M. B. H., Edmondson, D. E., & Tipton, K. F. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1883 · Cited by 1,374 · see citing works

Biomarkers of Oxidative Damage in Human Disease

Dalle-Donne, I., Rossi, R., Colombo, R., Giustarini, D., & Milzani, A. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2005.061408 · Cited by 1,703 · see citing works

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

Tan, B. L., Norhaizan, M. E., Liew, W.-P.-P., & Rahman, H. S. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01162 · Cited by 1,182 · see citing works

Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease

Ngo, V., & Duennwald, M. L. (2022) · Antioxidants · doi:10.3390/antiox11122345 · Cited by 1,130 · see citing works

Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action

Rudrapal, M., Khairnar, S. J., Khan, J., Dukhyil, A. B., Ansari, M. A., Alomary, M. N., Alshabrmi, F. M., Palai, S., Deb, P. K., & Devi, R. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.806470 · Cited by 1,103 · see citing works

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

Ng, F., Berk, M., Dean, O., & Bush, A. I. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145707008401 · Cited by 1,069 · see citing works

Synthetic fluorescent sensors for studying the cell biology of metals

Domaille, D. W., Que, E. L., & Chang, C. J. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.69 · Cited by 1,080 · see citing works

An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases

Teleanu, D. M., Niculescu, A.-G., Lungu, I. I., Radu, C. I., Vladâcenco, O., Roza, E., Costăchescu, B., Grumezescu, A. M., & Teleanu, R. I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23115938 · Cited by 1,085 · see citing works

NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

Xie, N., Zhang, L., Gao, W. Q., Huang, C., Huber, P., Zhou, X., Li, C. L., Shen, G., & Zou, B. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00311-7 · Cited by 1,076 · see citing works

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

Zilka, O., Shah, R., Li, B., Angeli, J. P. F., Grießer, M., Conrad, M., & Pratt, D. A. (2017) · ACS Central Science · doi:10.1021/acscentsci.7b00028 · Cited by 1,052 · see citing works

Metals, oxidative stress and neurodegenerative disorders

Jomová, K., Vondráková, D., Lawson, M. K., & Valko, M. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0563-x · Cited by 1,053 · see citing works

Small-Molecule Two-Photon Probes for Bioimaging Applications

Kim, H. M., & Cho, B. R. (2015) · Chemical Reviews · doi:10.1021/cr5004425 · Cited by 1,047 · see citing works

Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species

Chen, X., Tian, X., Shin, I., & Yoon, J. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15037e · Cited by 980 · see citing works

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

Liu, L., Zhang, K., Sandoval, H., Yamamoto, S., Jaiswal, M., Sanz, E., Li, Z., Hui, J., Graham, B. H., Quintana, A., et al. (2015) · Cell · doi:10.1016/j.cell.2014.12.019 · Cited by 876 · see citing works

ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection

Cadenas, S. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.01.024 · Cited by 819 · see citing works

A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells

Zeng, L., Miller, E. W., Pralle, A., Isacoff, E. Y., & Chang, C. J. (2005) · Journal of the American Chemical Society · doi:10.1021/ja055064u · Cited by 806 · see citing works

Metal coordination in photoluminescent sensing

Liu, Z., He, W., & Guo, Z. (2013) · Chemical Society Reviews · doi:10.1039/c2cs35363f · Cited by 803 · see citing works

The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An Update

Lu, M., Ji, J., Jiang, Z., & You, Q. (2016) · Medicinal Research Reviews · doi:10.1002/med.21396 · Cited by 801 · see citing works

Oxidative stress response and Nrf2 signaling in aging

Zhang, H., Davies, K. J. A., & Forman, H. J. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.036 · Cited by 804 · see citing works

Obesity and neuroinflammation: A pathway to cognitive impairment

Miller, A. A., & Spencer, S. J. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.04.001 · Cited by 788 · see citing works

Fenton-like copper redox chemistry revisited: Hydrogen peroxide and superoxide mediation of copper-catalyzed oxidant production

Pham, A. N., Xing, G., Miller, C. J., & Waite, T. D. (2013) · Journal of Catalysis · doi:10.1016/j.jcat.2013.01.025 · Cited by 758 · see citing works

Small Molecule Modulators of <scp>K</scp> eap1‐ <scp>N</scp> rf2‐ <scp>ARE</scp> Pathway as Potential Preventive and Therapeutic Agents

Magesh, S., Chen, Y., & Hu, L. (2012) · Medicinal Research Reviews · doi:10.1002/med.21257 · Cited by 760 · see citing works

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Kondo, T., Asai, M., Tsukita, K., Kutoku, Y., Ohsawa, Y., Sunada, Y., Imamura, K., Egawa, N., Yahata, N., Okita, K., et al. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.01.009 · Cited by 741 · see citing works

The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer

Kalinowski, D. S., & Richardson, D. R. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.4.2 · Cited by 721 · see citing works

The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases

Tu, W., Wang, H., Li, S., Liu, Q., & Sha, H. (2018) · Aging and Disease · doi:10.14336/ad.2018.0513 · Cited by 712 · see citing works

Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse

Parsons, C. G., Stöffler, A., & Danysz, W. (2007) · Neuropharmacology · doi:10.1016/j.neuropharm.2007.07.013 · Cited by 701 · see citing works

Animal models of Alzheimer's disease and frontotemporal dementia

Götz, J., & Ittner, L. M. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2420 · Cited by 676 · see citing works

Overcoming the Blood–Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

Furtado, D., Björnmalm, M., Ayton, S., Bush, A. I., Kempe, K., & Caruso, F. (2018) · Advanced Materials · doi:10.1002/adma.201801362 · Cited by 708 · see citing works

NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer’s diseases

Park, M. W., Cha, H. W., Kim, J., Kim, J. H., Yang, H., Yoon, S., Boonpraman, N., Yi, S. S., Yoo, I. D., & Moon, J.-S. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101947 · Cited by 683 · see citing works

Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species

Wu, L., Sedgwick, A. C., Sun, X., Bull, S. D., He, X., & James, T. D. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00302 · Cited by 669 · see citing works

A Redox Modulatory Mn 3 O 4 Nanozyme with Multi‐Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model

Singh, N., Savanur, M. A., Srivastava, S., D’Silva, P., & Mugesh, G. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201708573 · Cited by 660 · see citing works

Hazardous effects of chemical pesticides on human health–Cancer and other associated disorders

Sabarwal, A., Kumar, K., & Singh, R. P. (2018) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2018.08.018 · Cited by 659 · see citing works

Exercise-induced oxidative stress: Friend or foe?

Powers, S. K., Deminice, R., Ozdemir, M., Yoshihara, T., Bomkamp, M. P., & Hyatt, H. (2020) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.04.001 · Cited by 655 · see citing works

A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells

Chang, M. C. Y., Pralle, A., Isacoff, E. Y., & Chang, C. J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0441716 · Cited by 652 · see citing works

A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells

Dickinson, B. C., & Chang, C. J. (2008) · Journal of the American Chemical Society · doi:10.1021/ja802355u · Cited by 642 · see citing works

Fluorogenic probes for disease-relevant enzymes

Zhang, J., Chai, X., He, X., Kim, H.-J., Yoon, J., & Tian, H. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00907k · Cited by 606 · see citing works

Nanocatalytic Medicine

Yang, B., Chen, Y., & Shi, J. (2019) · Advanced Materials · doi:10.1002/adma.201901778 · Cited by 604 · see citing works

Carbon‐Dot‐Based Dual‐Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions

Zhu, A., Qu, Q., Shao, X., Kong, B., & Tian, Y. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201109089 · Cited by 602 · see citing works

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade

Savelieff, M. G., Nam, G., Kang, J., Lee, H. J., Lee, M., & Lim, M. H. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00138 · Cited by 603 · see citing works

Boronate-based fluorescent probes for imaging cellular hydrogen peroxide.

Miller, E. W., Albers, A. E., Pralle, A., Isacoff, E., & Chang, C. J. (2005) · Journal of the American Chemical Society · doi:10.1021/ja054474f · Cited by 530 · see citing works

Tetraphenylethylene-Based AIE-Active Probes for Sensing Applications

La, D. D., Bhosale, S. V., Jones, L. A., & Bhosale, S. V. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b12320 · Cited by 591 · see citing works

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease

Jiang, T., Sun, Q., & Chen, S. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.07.005 · Cited by 594 · see citing works

Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics

Belaidi, A. A., & Bush, A. I. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13425 · Cited by 580 · see citing works

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

Maalouf, M., Rho, J. M., & Mattson, M. P. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.09.002 · Cited by 575 · see citing works

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554 · see citing works

Synthetic fluorescent probes for studying copper in biological systems

Cotruvo, J. A., Aron, A. T., Ramos‐Torres, K. M., & Chang, C. J. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00346b · Cited by 561 · see citing works

Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue

Massudi, H., Grant, R., Braidy, N., Guest, J., Farnsworth, B., & Guillemin, G. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042357 · Cited by 545 · see citing works

Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke

Liu, Y., Ai, K., Ji, X., Askhatova, D., Du, R., Lu, L., & Shi, J. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b11013 · Cited by 548 · see citing works

Protein carbonylation as a major hallmark of oxidative damage: Update of analytical strategies

Fedorova, M., Bollineni, R. C., & Hoffmann, R. (2013) · Mass Spectrometry Reviews · doi:10.1002/mas.21381 · Cited by 516 · see citing works

A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells

Dickinson, B. C., Huynh, C., & Chang, C. J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1014103 · Cited by 513 · see citing works

Nrf2/Keap1/ARE signaling: Towards specific regulation

Ulasov, A. V., Rosenkranz, A. A., Georgiev, G. P., & Sobolev, A. S. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120111 · Cited by 520 · see citing works

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

Theillet, F., Binolfi, A., Frembgen-Kesner, T., Hingorani, K. S., Sarkar, M., Kyne, C., Li, C., Crowley, P. B., Gierasch, L. M., Pielak, G. J., et al. (2014) · Chemical Reviews · doi:10.1021/cr400695p · Cited by 504 · see citing works

Auranofin: Repurposing an Old Drug for a Golden New Age

Röder, C., & Thomson, M. J. (2015) · Drugs in R&D · doi:10.1007/s40268-015-0083-y · Cited by 499 · see citing works

Biological metals and metal-targeting compounds in major neurodegenerative diseases

Barnham, K. J., & Bush, A. I. (2014) · Chem. Soc. Rev. · doi:10.1039/c4cs00138a · Cited by 497 · see citing works

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

Zhang, X., Cheng, X., Yu, L., Yang, J., Calvo, R., Patnaik, S., Hu, X., Gao, Q., Yang, M., Lawas, M., et al. (2016) · Nature Communications · doi:10.1038/ncomms12109 · Cited by 558 · see citing works

Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

Adibhatla, R. M., & Hatcher, J. F. (2010) · Antioxidants &amp; Redox Signaling · doi:10.1089/ars.2009.2668 · Cited by 480 · see citing works

High-Mobility Group Box 1, Oxidative Stress, and Disease

Tang, D., Kang, R., Zeh, H. J., & Lotze, M. T. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3356 · Cited by 465 · see citing works

Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders

Sas, K., Robotka, H., Toldi, J., & Vécsei, L. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.01.033 · Cited by 465 · see citing works

Oxidative stress in Alzheimer disease

Gella, A., & Durany, N. (2009) · Cell Adhesion &amp; Migration · doi:10.4161/cam.3.1.7402 · Cited by 459 · see citing works

Role of mitochondrial DNA in toxic responses to oxidative stress

Houten, B. V., Woshner, V. M., & Santos, J. H. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.03.002 · Cited by 455 · see citing works

Peroxide detoxification by brain cells

Dringen, R., Pawlowski, P. G., & Hirrlinger, J. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20280 · Cited by 452 · see citing works

Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles

Wang, J., Liu, Y., Fang, J., Lao, F., Li, W., Gu, Y., Li, Y., Ge, C., Zhou, G., Li, B., et al. (2008) · Toxicology · doi:10.1016/j.tox.2008.09.014 · Cited by 451 · see citing works

Labeling Live Cells by Copper-Catalyzed Alkyne−Azide Click Chemistry

Hong, V., Steinmetz, N. F., Manchester, M., & Finn, M. G. (2010) · Bioconjugate Chemistry · doi:10.1021/bc100272z · Cited by 433 · see citing works

Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?

de Vries, H. E., Witte, M. E., Hondius, D., Rozemüller, A. J. M., Drukarch, B., Hoozemans, J. J. M., & van Horssen, J. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.09.001 · Cited by 432 · see citing works

Modern reaction-based indicator systems

Cho, D., & Sessler, J. L. (2009) · Chemical Society Reviews · doi:10.1039/b804436h · Cited by 422 · see citing works

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Tian, R., Abarientos, A., Hong, J., Hashemi, S. H., Yan, R., Dräger, N., Leng, K., Nalls, M. A., Singleton, A. B., Xu, K., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00862-0 · Cited by 414 · see citing works

Hepatocyte-Targeting Single Galactose-Appended Naphthalimide: A Tool for Intracellular Thiol Imaging in Vivo

Lee, M. H., Han, J. H., Kwon, P. S., Bhuniya, S., Kim, J. Y., Sessler, J. L., Kang, C., & Kim, J. S. (2011) · Journal of the American Chemical Society · doi:10.1021/ja210065g · Cited by 408 · see citing works

Antiinflammatory Activity of Melatonin in Central Nervous System

Esposito, E., & Cuzzocrea, S. (2010) · Current Neuropharmacology · doi:10.2174/157015910792246155 · Cited by 408 · see citing works

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

de Bittner, G. C. V., Goun, E. A., Bertozzi, C. R., & Chang, C. J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012864107 · Cited by 403 · see citing works

The Rise of Boron-Containing Compounds: Advancements in Synthesis, Medicinal Chemistry, and Emerging Pharmacology

Grams, R. J., Santos, W. L., Scorei, I. R., Abad-García, A., Rosenblum, C. A., Biţă, A., Cerecetto, H., Viñas, C., & Soriano-Ursua, M. A. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00663 · Cited by 389 · see citing works

Chemodosimeters: An approach for detection and estimation of biologically and medically relevant metal ions, anions and thiols

Kaur, K., Saini, R., Kumar, A., Luxami, V., Kaur, N., Singh, P., & Kumar, S. (2012) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2012.04.013 · Cited by 381 · see citing works

A FRET-Based Approach to Ratiometric Fluorescence Detection of Hydrogen Peroxide

Albers, A. E., Okreglak, V., & Chang, C. J. (2006) · Journal of the American Chemical Society · doi:10.1021/ja063308k · Cited by 375 · see citing works

Recent developments on polyphenol–protein interactions: effects on tea and coffee taste, antioxidant properties and the digestive system

Bandyopadhyay, P., Ghosh, A. K., & Ghosh, C. (2012) · Food & Function · doi:10.1039/c2fo00006g · Cited by 375 · see citing works

Life or death: Neuroprotective and anticancer effects of quercetin

Dajas, F. (2012) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2012.07.005 · Cited by 379 · see citing works

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease

Hou, K., Zhao, J., Wang, H., Li, B., Li, K., Shi, X., Wan, K., Ai, J., Lv, J., Wang, D., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18525-2 · Cited by 373 · see citing works

Curcumin-loaded nanoparticles: a novel therapeutic strategy in treatment of central nervous system disorders

Yavarpour‐Bali, H., Ghasemi‐Kasman, M., & Pirzadeh, M. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s208332 · Cited by 367 · see citing works

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples

Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361 · see citing works

Misfolded proteins in Alzheimer's disease and type II diabetes

DeToma, A. S., Salamekh, S., Ramamoorthy, A., & Lim, M. H. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15112f · Cited by 359 · see citing works

Metallostasis in Alzheimer's disease

Ayton, S., Lei, P., & Bush, A. I. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.10.558 · Cited by 354 · see citing works

Visualizing Ascorbate-Triggered Release of Labile Copper within Living Cells using a Ratiometric Fluorescent Sensor

Domaille, D. W., Zeng, L., & Chang, C. J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja907778b · Cited by 352 · see citing works

Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease

Korte, N., Nortley, R., & Attwell, D. (2020) · Acta Neuropathologica · doi:10.1007/s00401-020-02215-w · Cited by 343 · see citing works

Mechanism of alcohol-induced oxidative stress and neuronal injury

Haorah, J., Ramirez, S. H., Floreani, N. A., Gorantla, S., Morsey, B., & Persidsky, Y. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.08.030 · Cited by 349 · see citing works

Amyloid-β Aggregation

Finder, V. H., & Glockshuber, R. (2007) · Neurodegenerative Diseases · doi:10.1159/000100355 · Cited by 350 · see citing works

Aldazine-based colorimetric sensors for Cu2+ and Fe3+

Narayanaswamy, N., & Govindaraju, T. (2011) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2011.10.036 · Cited by 347 · see citing works

Oxidative stress in neurodegenerative diseases

Javaid, M., Arain, F. M., & Javaid, M. D. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18807-7.00011-9 · Cited by 2 · see citing works

Oxidative stress modulation in neurodegenerative diseases

Carlesi, C., Ienco, E. C., Piazza, S., Gerfo, A. L., Alessi, R., Pasquali, L., & Siciliano, G. (2011) · Mediterranean Journal of Nutrition and Metabolism · doi:10.1007/s12349-011-0055-x

Is Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative Diseases

Chiurchiù, V., Orlacchio, A., & Maccarrone, M. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/7909380 · Cited by 156 · see citing works

Oxidative stress mechanisms and potential therapeutics in Alzheimer disease

Moreira, P. I., Siedlak, S. L., Aliev, G., Zhu, X., Cash, A., Smith, M. A., & Perry, G. L. (2004) · Journal of Neural Transmission · doi:10.1007/s00702-004-0242-8 · Cited by 116 · see citing works

Oxidative Stress in Neurodegenerative Diseases: From Preclinical Studies to Clinical Applications

Tarozzi, A. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9041223 · Cited by 21 · see citing works