The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Flexible Porous Metal-Organic Frameworks for a Controlled Drug Delivery
Abstract
Flexible nanoporous chromium or iron terephtalates (BDC) MIL-53(Cr, Fe) or M(OH)[BDC] have been used as matrices for the adsorption and in vitro drug delivery of Ibuprofen (or alpha- p-isobutylphenylpropionic acid). Both MIL-53(Cr) and MIL-53(Fe) solids adsorb around 20 wt % of Ibuprofen (Ibuprofen/dehydrated MIL-53 molar ratio = 0.22(1)), indicating that the amount of inserted drug does not depend on the metal (Cr, Fe) constitutive of the hybrid framework. Structural and spectroscopic characterizations are provided for the solid filled with Ibuprofen. In each case, the very slow and complete delivery of Ibuprofen was achieved under physiological conditions after 3 weeks with a predictable zero-order kinetics, which highlights the unique properties of flexible hybrid solids for adapting their pore opening to optimize the drug-matrix interactions.
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Cites
Modeling and comparison of dissolution profiles
Costa, P., & Sousa Lobo, J. M. (2001) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(01)00095-1 · Cited by 5,509
Biodegradable polymeric nanoparticles as drug delivery devices
Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00339-4 · Cited by 3,549
Cited by
Horike, S., Shimomura, S., & Kitagawa, S. (2009) · Nature Chemistry · doi:10.1038/nchem.444 · Cited by 2,486
BioMOFs: Metal–Organic Frameworks for Biological and Medical Applications
McKinlay, A. C., Morris, R. E., Horcajada, P., Férey, G., Gref, R., Couvreur, P., & Serre, C. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201000048 · Cited by 1,256
Self-citationYusuf, V. F., Malek, N. I., & Kailasa, S. K. (2022) · ACS Omega · doi:10.1021/acsomega.2c05310 · Cited by 894
Zeolitic imidazolate framework-8 as efficient pH-sensitive drug delivery vehicle
Sun, C.-Y., Qin, C., Wang, X.-L., Yang, G.-S., Shao, K.-Z., Lan, Y.-Q., Su, Z.-M., Huang, P., Wang, C.-G., & Wang, E.-B. (2012) · Dalton Transactions · doi:10.1039/c2dt30357d · Cited by 710
Metal-organic frameworks for advanced drug delivery
He, S., Wu, L., Li, X., Sun, H., Xiong, T., Liu, J., Huang, C., Xu, H., Sun, H., Chen, W., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.019 · Cited by 528
Metadata
- Authors
- Horcajada, P., Serre, C., Maurin, G., Ramsahye, N. A., Balas, F., Vallet-Regí, M., Sebban, M., Taulelle, F., & Férey, G.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-05-01
- Volume
- 130
- Issue
- 21
- Pages
- 6774-6780
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2082179062
- Cited by
- 1,794
- References
- 2
- FWCI
- 48.83
- Type
- journal article
- Language
- en
- Open access
- closed
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