The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Structural Basis of DNA Quadruplex Recognition by an Acridine Drug
Abstract
The crystal structure of a complex between the bimolecular human telomeric quadruplex d(TAGGGTTAGGGT)2 and the experimental anticancer drug BRACO-19, has been determined, to 2.5 A resolution. The binding site for the BRACO-19 molecule is at the interface of two parallel-folded quadruplexes, sandwiched between a G-tetrad surface and a TATA tetrad, and held in the site by networks of water molecules. The structure rationalizes the existing structure-activity data and provides a starting-point for the structure-based design of quadruplex-binding ligands
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Cites
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L., & Shay, J. W. (1994) · Science · doi:10.1126/science.7605428 · Cited by 7,091
Quadruplex DNA: sequence, topology and structure
Burge, S., Parkinson, G. N., Hazel, P., Todd, A. K., & Neidle, S. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl655 · Cited by 2,408
Self-citationCrystal structure of parallel quadruplexes from human telomeric DNA
Parkinson, G. N., Lee, M. P. H., & Neidle, S. (2002) · Nature · doi:10.1038/nature755 · Cited by 2,031
Self-citationInhibition of telomerase by G-quartet DMA structures
Zahler, A. M., Williamson, J. R., Cech, T. R., & Prescott, D. M. (1991) · Nature · doi:10.1038/350718a0 · Cited by 1,134
Ambrus, A., Chen, D., Dai, J., Bialis, T., Jones, R. A., & Yang, D. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl348 · Cited by 1,106
Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound
Sun, D., Thompson, B., Cathers, B. E., Salazar, M., Kerwin, S. M., Trent, J. O., Jenkins, T. C., Neidle, S., & Hurley, L. H. (1997) · Journal of Medicinal Chemistry · doi:10.1021/jm970199z · Cited by 794
Self-citationAmbrus, A., Chen, D., Dai, J., Jones, R. A., & Yang, D. (2005) · Biochemistry · doi:10.1021/bi048242p · Cited by 683
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Self-citationTargeting telomeres and telomerase
De Cian, A., Lacroix, L., Douarre, C., Temime-Smaali, N., Trentesaux, C., Riou, J.-F., & Mergny, J.-L. (2008) · Biochimie · doi:10.1016/j.biochi.2007.07.011 · Cited by 572
Phan, A. T., Kuryavyi, V., Luu, K. N., & Patel, D. J. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm706 · Cited by 520
Cited by
Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA
Xu, Y. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00134a · Cited by 323
Metadata
- Authors
- Campbell, N. H., Parkinson, G. N., Reszka, A. P., & Neidle, S.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-05-01
- Volume
- 130
- Issue
- 21
- Pages
- 6722-6724
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2028526843
- Cited by
- 326
- References
- 22
- FWCI
- 10.42
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
