The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Single Biomolecule Imaging by Electrochemiluminescence
Open accessAbstract
-doped silica/Au nanoparticles (RuDSNs/AuNPs) as the ECL nanoemitters. The ECL emission is confined to the local surface of RuDSNs leading to a significant enhancement in the intensity. To prove the concept, a single protein molecule at the electrode is initially visualized using the as-prepared RuDSN/AuNPs nanoemitters. Furthermore, the nanoemitter-labeled antibody is linked at the cellular membrane to image a single membrane protein at one cell, without the interference of current and optical background. The success in single-biomolecule ECL imaging solves the long-lasting task in the ultrasensitive ECL analysis, which should be able to provide more elegant information about the protein in cellular biology.
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Counting Low-Copy Number Proteins in a Single Cell
Huang, B., Wu, H., Bhaya, D., Grossman, A., Granier, S., Kobilka, B. K., & Zare, R. N. (2007) · Science · doi:10.1126/science.1133992 · Cited by 387
Direct imaging of single-molecule electrochemical reactions in solution
Dong, J., Lu, Y., Xu, Y., Chen, F., Yang, J., Chen, Y., & Feng, J. (2021) · Nature · doi:10.1038/s41586-021-03715-9 · Cited by 369
Single‐Molecule Sensors: Challenges and Opportunities for Quantitative Analysis
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Surface-Confined Electrochemiluminescence Microscopy of Cell Membranes
Voci, S., Goudeau, B., Valenti, G., Lesch, A., Jović, M., Rapino, S., Paolucci, F., Arbault, S., & Sojic, N. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.8b08080 · Cited by 301
Self-citationFluorescent Biosensors Based on Single-Molecule Counting
Ma, F., Li, Y., Tang, B., & Zhang, C.-Y. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00237 · Cited by 288
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Self-citationBreaking the concentration limit of optical single-molecule detection
Holzmeister, P., Acuna, G. P., Grohmann, D., & Tinnefeld, P. (2014) · Chem. Soc. Rev. · doi:10.1039/c3cs60207a · Cited by 218
Metadata
- Authors
- Liu, Y., Zhang, H., Li, B., Liu, J., Jiang, D., Liu, B., & Sojic, N.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2021-10-22
- Volume
- 143
- Issue
- 43
- Pages
- 17910-17914
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W3206456078
- Cited by
- 303
- References
- 25
- FWCI
- 13.82
- Type
- journal article
- Language
- en
- Open access
- green
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