The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Large-Scale Hot Spot Engineering for Quantitative SERS at the Single-Molecule Scale
Abstract
Quantitative surface enhanced Raman spectroscopy (SERS) requires precise control of Raman enhancement factor and detection uniformity across the SERS substrate. Here, we show that alkanethiolate ligand-regulated silver (Ag) nanoparticle films can be used to achieve quantitative SERS measurements down to the single-molecule level. The two-dimensional hexagonal close-packed superlattices of Ag nanoparticles formed in these films allow for SERS detection over a large area with excellent uniformity and high Raman enhancement factor. In particular, the SERS signal from the thiolate ligands on Ag nanoparticle surfaces can be utilized as a stable internal calibration standard for reproducible quantitative measurements. We demonstrate the capability of quantitative SERS by measuring the areal densities of crystal violet molecules embedded in an ultrathin spin-on-glass detection "hot zone", which is a planar and uniformly enhanced region several nanometers above the Ag nanoparticles. The Raman measurement results exhibit a linear response over a wide dynamic range of analyte concentration.
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Cites
Optical Constants of the Noble Metals
Johnson, P. B., & Christy, R. W. (1972) · Physical Review B · doi:10.1103/physrevb.6.4370 · Cited by 20,094
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Nie, S., & Emory, S. R. (1997) · Science · doi:10.1126/science.275.5303.1102 · Cited by 10,238
Raman spectra of pyridine adsorbed at a silver electrode
Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974) · Chemical Physics Letters · doi:10.1016/0009-2614(74)85388-1 · Cited by 7,172
Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)
Kneipp, K., Wang, Y., Kneipp, H., Perelman, L. T., Itzkan, I., Dasari, R. R., & Feld, M. S. (1997) · Physical Review Letters · doi:10.1103/physrevlett.78.1667 · Cited by 6,816
Moskovits, M. (1985) · Reviews of Modern Physics · doi:10.1103/revmodphys.57.783 · Cited by 5,466
Surface raman spectroelectrochemistry
Jeanmaire, D. L., & Van Duyne, R. P. (1977) · Journal of Electroanalytical Chemistry and Interfacial Electrochemistry · doi:10.1016/s0022-0728(77)80224-6 · Cited by 4,738
Shell-isolated nanoparticle-enhanced Raman spectroscopy
Li, J. F., Huang, Y. F., Ding, Y., Yang, Z. L., Li, S. B., Zhou, X. S., Fan, F. R., Zhang, W., Zhou, Z. Y., Wu, D. Y., et al. (2010) · Nature · doi:10.1038/nature08907 · Cited by 3,559
Surface Enhanced Raman Scattering Enhancement Factors: A Comprehensive Study
Le Ru, E. C., Blackie, E., Meyer, M., & Etchegoin, P. G. (2007) · The Journal of Physical Chemistry C · doi:10.1021/jp0687908 · Cited by 2,853
Principles of Surface-Enhanced Raman Spectroscopy: and Related Plasmonic Effects
Ru, E. C. L., & Etchegoin, P. (2008) · Cited by 1,455
Self-Assembled Metal Colloid Monolayers: An Approach to SERS Substrates
Freeman, R. G., Grabar, K. C., Allison, K. J., Bright, R. M., Davis, J. A., Guthrie, A. P., Hommer, M. B., Jackson, M. A., Smith, P. C., Walter, D. G., et al. (1995) · Science · doi:10.1126/science.267.5204.1629 · Cited by 1,289
Cited by
Qiao, X., Su, B., Liu, C., Song, Q., Luo, D., Mo, G., & Wang, T. (2018) · Advanced Materials · doi:10.1002/adma.201702275 · Cited by 469
Metadata
- Authors
- Chen, H.-Y., Lin, M.-H., Wang, C.-Y., Chang, Y.-M., & Gwo, S.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-10-15
- Volume
- 137
- Issue
- 42
- Pages
- 13698-13705
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2299637118
- Cited by
- 426
- References
- 31
- FWCI
- 13.34
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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