The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Enhanced Activity of Enzymes Encapsulated in Hydrophilic Metal–Organic Frameworks
Abstract
Encapsulation of biomacromolecules in metal-organic frameworks (MOFs) can preserve biological functionality in harsh environments. Despite the success of this approach, termed biomimietic mineralization, limited consideration has been given to the chemistry of the MOF coating. Here, we show that enzymes encapsulated within hydrophilic MAF-7 or ZIF-90 retain enzymatic activity upon encapsulation and when exposed to high temperatures, denaturing or proteolytic agents, and organic solvents, whereas hydrophobic ZIF-8 affords inactive catalase and negligible protection to urease.
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Cites
The Chemistry and Applications of Metal-Organic Frameworks
Furukawa, H., Cordova, K. E., O’Keeffe, M., & Yaghi, O. M. (2013) · Science · doi:10.1126/science.1230444 · Cited by 16,945
Exceptional chemical and thermal stability of zeolitic imidazolate frameworks
Park, K. S., Ni, Z., Côté, A. P., Choi, J. Y., Huang, R., Uribe-Romo, F. J., Chae, H. K., O’Keeffe, M., & Yaghi, O. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602439103 · Cited by 7,563
Infrared spectroscopy of proteins
Barth, A. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2007.06.004 · Cited by 5,129
The Use and Misuse of FTIR Spectroscopy in the Determination of Protein Structure
Jackson, M., & Mantsch, H. H. (1995) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239509085140 · Cited by 2,037
Role of Biocatalysis in Sustainable Chemistry
Sheldon, R. A., & Woodley, J. M. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00203 · Cited by 1,755
Understanding protein adsorption phenomena at solid surfaces
Rabe, M., Verdes, D., & Seeger, S. (2011) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2010.12.007 · Cited by 1,664
Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules
Liang, K., Ricco, R., Doherty, C. M., Styles, M. J., Bell, S., Kirby, N., Mudie, S., Haylock, D., Hill, A. J., Doonan, C. J., et al. (2015) · Nature Communications · doi:10.1038/ncomms8240 · Cited by 1,496
Self-citationMechanisms of Tryptophan Fluorescence Shifts in Proteins
Vivian, J. T., & Callis, P. R. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)76183-8 · Cited by 1,493
Crystals as Molecules: Postsynthesis Covalent Functionalization of Zeolitic Imidazolate Frameworks
Morris, W., Doonan, C. J., Furukawa, H., Banerjee, R., & Yaghi, O. M. (2008) · Journal of the American Chemical Society · doi:10.1021/ja805222x · Cited by 779
Self-citationShieh, F.-K., Wang, S.-C., Yen, C.-I., Wu, C.-C., Dutta, S., Chou, L.-Y., Morabito, J. V., Hu, P., Hsu, M.-H., Wu, K. C.-W., et al. (2015) · Journal of the American Chemical Society · doi:10.1021/ja513058h · Cited by 774
Cited by
Bioinspired Framework Catalysts: From Enzyme Immobilization to Biomimetic Catalysis
Wang, K.-Y., Zhang, J., Hsu, Y.-C., Lin, H., Han, Z., Pang, J., Yang, Z., Liang, R.-R., Shi, W., & Zhou, H.-C. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00879 · Cited by 490
Metal-organic frameworks as novel matrices for efficient enzyme immobilization: An update review
Liang, S., Wu, X.-L., Xiong, J., Zong, M.-H., & Lou, W.-Y. (2020) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2019.213149 · Cited by 441
Metadata
- Authors
- Liang, W., Xu, H., Carraro, F., Maddigan, N. K., Li, Q., Bell, S. G., Huang, D. M., Tarzia, A., Solomon, M. B., Amenitsch, H., Vaccari, L., Sumby, C. J., Falcaro, P., & Doonan, C. J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-01-12
- Volume
- 141
- Issue
- 6
- Pages
- 2348-2355
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2908532599
- Cited by
- 560
- References
- 33
- FWCI
- 21.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- Liang, W., Xu, H., Carraro, F., Maddigan, N. K., Li, Q., Bell, S. G., Huang, D. M., Tarzia, A., Solomon, M. B., Amenitsch, H., Vaccari, L., Sumby, C. J., Falcaro, P., & Doonan, C. J. (2019). Enhanced Activity of Enzymes Encapsulated in Hydrophilic Metal–Organic Frameworks. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.8b10302
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