The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Major Flavonoids in Grape Seeds and Skins: Antioxidant Capacity of Catechin, Epicatechin, and Gallic Acid
Abstract
Grape seeds and skins are good sources of phytochemicals such as gallic acid, catechin, and epicatechin and are suitable raw materials for the production of antioxidative dietary supplements. The differences in levels of the major monomeric flavanols and phenolic acids in seeds and skins from grapes of Vitis vinifera varieties Merlot and Chardonnay and in seeds from grapes of Vitis rotundifolia variety Muscadine were determined, and the antioxidant activities of these components were assessed. The contribution of the major monomeric flavonols and phenolic acid to the total antioxidant capacity of grape seeds and skins was also determined. Gallic acid, monomeric catechin, and epicatechin concentrations were 99, 12, and 96 mg/100 g of dry matter (dm) in Muscadine seeds, 15, 358, and 421 mg/100 g of dm in Chardonnay seeds, and 10, 127, and 115 mg/100 g of dm in Merlot seeds, respectively. Concentrations of these three compounds were lower in winery byproduct grape skins than in seeds. These three major phenolic constituents of grape seeds contributed <26% to the antioxidant capacity measured as ORAC on the basis of the corrected concentrations of gallic acid, catechin, and epicatechin in grape byproducts. Peroxyl radical scavenging activities of phenolics present in grape seeds or skins in decreasing order were resveratrol > catechin > epicatechin = gallocatechin > gallic acid = ellagic acid. The results indicated that dimeric, trimeric, oligomeric, or polymeric procyanidins account for most of the superior antioxidant capacity of grape seeds.
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Citations
Cites
Assessing Antioxidant and Prooxidant Activities of Phenolic Compounds
Fukumoto, L. R., & Mazza, G. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf000220w · Cited by 1,660
Morel, I., Lescoat, G., Cogrel, P., Sergent, O., Pasdeloup, N., Brissot, P., Cillard, P., & Cillard, J. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90371-3 · Cited by 635
Antioxidant activity of flavonoids and reactivity with peroxy radical
Torel, J., Cillard, J., & Cillard, P. (1986) · Phytochemistry · doi:10.1016/s0031-9422(00)85485-0 · Cited by 602
Potential health impacts of excessive flavonoid intake
Skibola, C. F., & Smith, M. T. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00304-x · Cited by 569
Polymeric proanthocyanidins from grape skins
Souquet, J.-M., Cheynier, V., Brossaud, F., & Moutounet, M. (1996) · Phytochemistry · doi:10.1016/0031-9422(96)00301-9 · Cited by 522
Sánchez-Moreno, C., A. Larrauri, J., & Saura-Calixto, F. (1999) · Food Research International · doi:10.1016/s0963-9969(99)00097-6 · Cited by 472
Yamakoshi, J., Kataoka, S., Koga, T., & Ariga, T. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(98)00230-5 · Cited by 364
Mechanism of inhibition of tannic acid and related compounds on the growth of intestinal bacteria
Chung, K.-T., Lu, Z., & Chou, M. W. (1998) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(98)00086-6 · Cited by 337
Revilla, E., & Ryan, J.-M. (2000) · Journal of Chromatography A · doi:10.1016/s0021-9673(00)00269-7 · Cited by 228
Evaluation of the Antioxidant Actions of Ferulic Acid and Catechins
Scott, B. C., Butler, J., Halliwell, B., & Aruoma, O. I. (1993) · Free Radical Research Communications · doi:10.3109/10715769309056512 · Cited by 223
Cited by
Biological Activities of Polyphenols from Grapes
Xia, E.-Q., Deng, G.-F., Guo, Y.-J., & Li, H.-B. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11020622 · Cited by 1,063
Pinelo, M., Rubilar, M., Jerez, M., Sineiro, J., & Núñez, M. J. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0488110 · Cited by 616
Green tea and grape seed extracts—Potential applications in food safety and quality
Perumalla, A. V. S., & Hettiarachchy, N. S. (2011) · Food Research International · doi:10.1016/j.foodres.2011.01.022 · Cited by 471
Study of solid–liquid extraction kinetics of total polyphenols from grape seeds
Bucić-Kojić, A., Planinić, M., Tomas, S., Bilić, M., & Velić, D. (2007) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2006.10.027 · Cited by 444
Molecular diversity in phenolic and polyphenolic precursors of tannin-inspired nanocoatings
Barrett, D. G., Sileika, T. S., & Messersmith, P. B. (2014) · Chem. Commun. · doi:10.1039/c4cc02961e · Cited by 286
Metadata
- Authors
- Yilmaz, Y., & Toledo, R. T.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-12-31
- Volume
- 52
- Issue
- 2
- Pages
- 255-260
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2091099722
- Cited by
- 734
- References
- 27
- FWCI
- 8.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yilmaz, Y., & Toledo, R. T. (2004). Major Flavonoids in Grape Seeds and Skins: Antioxidant Capacity of Catechin, Epicatechin, and Gallic Acid. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf030117h
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