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ACE Inhibitory Peptides Derived from Enzymatic Hydrolysates of Animal Muscle Protein: A Review
Abstract
Naturally occurring ACE (angiotensin converting enzyme) inhibitory peptides have a potential as antihypertensive components in functional foods or nutraceuticals. These peptides have been discovered in various food sources from plant and animal protein origin. In this paper an overview is presented of the ACE inhibitory peptides obtained by enzymatic hydrolysis of muscle protein of meat, fish, and invertebrates. Some of these peptides do not only show in vitro ACE inhibitory activity but also in vivo antihypertensive activity in spontaneously hypertensive rats. To focus on new sources of ACE inhibitory peptides, more specifically insects and other invertebrates, we compared the vertebrate and invertebrate musculature and analyzed phylogenetic relationships.
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Citations
Cites
Bioactive milk peptides: a prospectus.
Clare, D. A., & Swaisgood, H. E. (2000) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(00)74983-6 · Cited by 718
Cited by
Food-derived peptides with biological activity: from research to food applications.
Hartmann, R., & Meisel, H. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.01.013 · Cited by 1,102
Algal Proteins: Extraction, Application, and Challenges Concerning Production
Bleakley, S., & Hayes, M. (2017) · Foods · doi:10.3390/foods6050033 · Cited by 1,092
The possible roles of food-derived bioactive peptides in reducing the risk of cardiovascular disease
Erdmann, K., Cheung, B. W. Y., & Schröder, H. (2008) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2007.11.010 · Cited by 717
Food protein functionality: A comprehensive approach
Foegeding, E. A., & Davis, J. P. (2011) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2011.05.008 · Cited by 486
Antioxidant and antimicrobial peptidic hydrolysates from muscle protein sources and by-products
Di Bernardini, R., Harnedy, P., Bolton, D., Kerry, J., O’Neill, E., Mullen, A. M., & Hayes, M. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.07.004 · Cited by 332
Metadata
- Authors
- Vercruysse, L., Van Camp, J., & Smagghe, G.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-09-21
- Volume
- 53
- Issue
- 21
- Pages
- 8106-8115
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1967881438
- Cited by
- 305
- References
- 1
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Vercruysse, L., Van Camp, J., & Smagghe, G. (2005). ACE Inhibitory Peptides Derived from Enzymatic Hydrolysates of Animal Muscle Protein: A Review. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf0508908
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.