The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen)
Abstract
As part of ongoing research on cancer chemopreventive agents from botanical dietary supplements, Garcinia mangostana L. (commonly known as mangosteen) was selected for detailed study. Repeated chromatography of a CH2Cl2-soluble extract of the pericarp led to the isolation of two new highly oxygenated prenylated xanthones, 8-hydroxycudraxanthone G (1) and mangostingone [7-methoxy-2-(3-methyl-2-butenyl)-8-(3-methyl-2-oxo-3-butenyl)-1,3,6-trihydroxyxanthone, 2], together with 12 known xanthones, cudraxanthone G (3), 8-deoxygartanin (4), garcimangosone B (5), garcinone D (6), garcinone E (7), gartanin (8), 1-isomangostin (9), alpha-mangostin (10), gamma-mangostin (11), mangostinone (12), smeathxanthone A (13), and tovophyllin A (14). The structures of compounds 1 and 2 were elucidated by spectroscopic data analysis. Except for compound 2, which was isolated as a minor component, the antioxidant activities of all isolates were determined using authentic and morpholinosydnonimine-derived peroxynitrite methods, and compounds 1, 8, 10, 11, and 13 were the most active. Alpha-mangostin (10) inhibited 7,12-dimethylbenz[alpha]anthracene-induced preneoplastic lesions in a mouse mammary organ culture assay with an IC50 of 1.0 microg/mL (2.44 microM).
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Cites
Oxidants, antioxidants, and the degenerative diseases of aging.
Ames, B. N., Shigenaga, M. K., & Hagen, T. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.17.7915 · Cited by 5,958
[23] Oxidative chemistry of peroxynitrite
Beckman, J. S., Chen, J., Ischiropoulos, H., & Crow, J. P. (1994) · Methods in Enzymology · doi:10.1016/s0076-6879(94)33026-3 · Cited by 973
Peroxynitrite-mediated oxidation of dihydrorhodamine 123
Kooy, N. W., Royall, J. A., Ischiropoulos, H., & Beckman, J. S. (1994) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)90138-4 · Cited by 719
International Collaboration on HIV and Cancer (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.22.1823 · Cited by 647
Prospective Study of Fruit and Vegetable Consumption and Incidence of Colon and Rectal Cancers
Michels, K. B. (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.21.1740 · Cited by 458
Prospective Study of Fruit and Vegetable Consumption and Risk of Lung Cancer Among Men and Women
Feskanich, D. (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.22.1812 · Cited by 454
Jacob, R., & Burri, B. (1996) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.6.985 · Cited by 407
van der Vliet, A., O'Neill, C. A., Halliwell, B., Cross, C. E., & Kaur, H. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)80391-9 · Cited by 381
[24] Nitric oxide assay using hemoglobin method
Murphy, M. E., & Noack, E. (1994) · Methods in Enzymology · doi:10.1016/s0076-6879(94)33027-1 · Cited by 360
Moongkarndi, P., Kosem, N., Kaslungka, S., Luanratana, O., Pongpan, N., & Neungton, N. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2003.09.048 · Cited by 348
Cited by
Garcinia mangostana L.: a phytochemical and pharmacological review
Obolskiy, D., Pischel, I., Siriwatanametanon, N., & Heinrich, M. (2009) · Phytotherapy Research · doi:10.1002/ptr.2730 · Cited by 366
Anti-Cancer Effects of Xanthones from Pericarps of Mangosteen
Akao, Y., Nakagawa, Y., & Nozawa, Y. (2008) · International Journal of Molecular Sciences · doi:10.3390/ijms9030355 · Cited by 275
Phenolic acid profiles of mangosteen fruits (Garcinia mangostana)
Zadernowski, R., Czaplicki, S., & Naczk, M. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2008.06.030 · Cited by 195
Ryu, H. W., Cho, J. K., Curtis-Long, M. J., Yuk, H. J., Kim, Y. S., Jung, S., Kim, Y. S., Lee, B. W., & Park, K. H. (2011) · Phytochemistry · doi:10.1016/j.phytochem.2011.08.007 · Cited by 161
Antioxidant and cytoprotective compounds from Berberis vulgaris (barberry)
Tomosaka, H., Chin, Y., Salim, A. A., Keller, W. J., Chai, H., & Kinghorn, A. D. (2008) · Phytotherapy Research · doi:10.1002/ptr.2443 · Cited by 97
Self-citation
Metadata
- Authors
- Jung, H.-A., Su, B.-N., Keller, W. J., Mehta, R. G., & Kinghorn, A. D.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-02-18
- Volume
- 54
- Issue
- 6
- Pages
- 2077-2082
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W1965055857
- Cited by
- 512
- References
- 26
- FWCI
- 15.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jung, H.-A., Su, B.-N., Keller, W. J., Mehta, R. G., & Kinghorn, A. D. (2006). Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen). Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf052649z
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