The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Garcinia mangostana L.: a phytochemical and pharmacological review
Abstract
Garcinia mangostana L. (mangosteen, Clusiaceae) has a long history of use as a medical plant, mostly in Southeast Asia. This is a review of the phytochemistry and pharmacology of mangosteen. Traditionally mangosteen is famous for its antiinflammatory properties and is used in the treatment of skin infections and wounds. Other applications include the therapy of various conditions such as dysentery, different urinary disorders, cystitis and gonorrhoea. This review highlights the development of this botanical drug into a widely used nutraceutical. Products derived from G. mangostana are now distributed increasingly all over the world. This has given rise to a concomitant increase in research on the phytochemical constituents and biological activity of mangosteen. Central to the biological activity of the species are xanthones which are reviewed in detail. A comprehensive assessment of the biological activities of individual xanthones as well as extracts of G. mangostana is included. In addition, its potential in terms of developing novel drug leads is assessed. Products containing its fruits are now sold widely as ‘liquid botanical supplements’, but evidence for the health benefits of these products is still lacking. As shown here, a serious weakness in our knowledge is the lack of clinical data and it is not yet clear to what extent the findings about pharmacological activities are of potential clinical relevance. Copyright © 2009 John Wiley & Sons, Ltd.
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Cites
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
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Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen)
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Xanthone Derivatives: New Insights in Biological Activities
Pinto, M. M. M., Sousa, M. E., & Nascimento, M. S. J. (2005) · Current Medicinal Chemistry · doi:10.2174/092986705774370691 · Cited by 481
Plant-Derived Leading Compounds for Chemotherapy of Human Immunodeficiency Virus (HIV) Infection
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Tetraoxygenated naturally occurring xanthones
Peres, V., Nagem, T. J., & de Oliveira, F. F. (2000) · Phytochemistry · doi:10.1016/s0031-9422(00)00303-4 · Cited by 402
Anti-inflammatory activity of mangostins from Garcinia mangostana
Chen, L.-G., Yang, L.-L., & Wang, C.-C. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.09.096 · Cited by 388
Moongkarndi, P., Kosem, N., Kaslungka, S., Luanratana, O., Pongpan, N., & Neungton, N. (2004) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2003.09.048 · Cited by 348
Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria
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Antimycobacterial Activity of Prenylated Xanthones from the Fruits of Garcinia mangostana
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Food as medicine and medicine as food
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Samprasit, W., Opanasopit, P., & Chamsai, B. (2021) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2021.1873370 · Cited by 50
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Metadata
- Authors
- Obolskiy, D., Pischel, I., Siriwatanametanon, N., & Heinrich, M.
- Venue
- Phytotherapy Research
- Publisher
- Wiley
- Published
- 2009-01-27
- Volume
- 23
- Issue
- 8
- Pages
- 1047-1065
- ISSN
- 0951-418X (ISSN-L)
- 1099-1573
- OpenAlex
- W1995614441
- Cited by
- 366
- References
- 34
- FWCI
- 18.14
- Type
- journal article
- Language
- en
- Open access
- closed
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