Coherence between legal requirements and approaches for detection of genetically modified organisms (GMOs) and their derived products
Abstract
Analytical methods for the qualitative and quantitative detection of genetically modified (GM) products may serve multiple purposes. Legal requirements differ among jurisdictions, ranging from no requirements to mandatory use of event-specific quantitation and implementation of production chain traceability. Although efforts have been taken to harmonize the analytical methodology at national, regional, and international levels, no normative international standards have yet been established. Lack of coherence between analytical methodologies and their applicabilities, on the one hand, and legislation, on the other hand, is a major problem. Here, key points where coherence is lacking are discussed. These include the definition of units of measurements, expression of GM material quantities, terminology, and inconsistent legal status of products derived from related but slightly different transformation routes. Finally, recommendations to improve the coherence are brought forward, including guidance to stakeholders for prediction of product-specific GM material quantities from gene ratios in the originating seed.
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Although efforts have been taken to harmonize analytical methodology for the detection of GE products at national, regional, and international levels, no international standards have yet been established.
“Although efforts have been taken to harmonize analytical methodology for the detection of GE products at national, regional, and international levels, no international standards have yet been established (Holst-Jensen et al., 2006).”
From Prevalence and impacts of genetically engineered feedstuffs on livestock populations1 (2014) · cites this paper as Holst-Jensen et al., 2006
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Höfferle, Š., Kramar, A., Smrekar, F., Štebih, D., Vojvoda, J., Žel, J., & Raspor, P. (2007) · Acta Biologica Slovenica · doi:10.14720/abs.50.1.14438
Kim, E.-H., Kim, B., Yoo, Y., Cho, Y.-S., Kim, Y. S., Lee, J. I., & Park, T. (2024) · Journal of Plant Biotechnology · doi:10.5010/jpb.2024.51.036.364
Morris, S. H. (2012) · ARAN (University of Galway Research Repository) (Ollscoil na Gaillimhe – University of Galway) · doi:10.13025/17619
- Authors
- Holst-Jensen, A., De Loose, M., & Van den Eede, G.
- Affiliations
- National Veterinary Institute, Ullevaalsveien 68, P.O. Box 8156 Dep., 0033 Oslo, Norway; Department for Plant Genetics and Breeding, Centre for Agricultural Research, Caritasstraat 21, B-9090 Melle, Belgium; and Food Products and Consumer Goods Unit, Institute for Health and Consumer Protection, European Commission, Joint Research Centre, I-21020 Ispra (VA), Italy
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2006-03-22
- Volume
- 54
- Issue
- 8
- Pages
- 2799-2809
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2029417763
- Cited by
- 93
- References
- 16
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 1 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 4 · 2013: 3 · 2012: 12
- FWCI
- 14.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Identification and Quantification in Food
- Keywords
- genetically modified organisms, GMO detection, legal requirements, analytical method harmonization, traceability, units of measurement, GMO regulation
- MeSH terms
- Base Sequence, Zea mays, Genetic Engineering, Genetic Markers, Seeds, DNA, Plant, Plants, Genetically Modified, Food, Genetically Modified
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