Cited by 85Genetically Modified Organisms ResearchIdentification and Quantification in FoodMolecular Biology Techniques and Applications

How to deal with the upcoming challenges in GMO detection in food and feed

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Broeders, Sylvia R. M., De Keersmaecker, Sigrid C. J., Roosens, Nancy H. C.·2012·Journal of Biomedicine and Biotechnology

Abstract

Biotech crops are the fastest adopted crop technology in the history of modern agriculture. The commercialisation of GMO is in many countries strictly regulated laying down the need for traceability and labelling. To comply with these legislations, detection methods are needed. To date, GM events have been developed by the introduction of a transgenic insert (i.e., promoter, coding sequence, terminator) into the plant genome and real-time PCR is the detection method of choice. However, new types of genetic elements will be used to construct new GMO and new crops will be transformed. Additionally, the presence of unauthorised GMO in food and feed samples might increase in the near future. To enable enforcement laboratories to continue detecting all GM events and to obtain an idea of the possible presence of unauthorised GMO in a food and feed sample, an intensive screening will become necessary. A pragmatic, cost-effective, and time-saving approach is presented here together with an overview of the evolution of the GMO and the upcoming needs.

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  • Some gene-editing techniques generate genetic changes that cannot be distinguished from conventionally bred crops or from crops produced by natural genetic variation or unregulated radiation mutagenesis.

    “Likewise, some gene-editing techniques generate genetic changes that cannot be distinguished from conventionally bred crops or from crops produced by natural genetic variation or unregulated radiation mutagenesis (Broeders et al., 2012).”

    From Prevalence and impacts of genetically engineered feedstuffs on livestock populations1 (2014) · cites this paper as Broeders et al., 2012

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  1. [3]European Parliament Commission regulation (EC) No 1830/2003 of the European Parliament and of the Council of 22 September 2003 concerning the traceability and labelling of genetically modified organisms and the traceability of food and feed products produced from genetically modified organisms and amending Directive 2001/18/EC Official Journal of the European Union 2003 L 268 24 28
  2. [77]European Parliament Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 on genetically modified food and feed Official Journal of the European Union 2003 L 268 1 23
  3. [78]European Commission Commission Regulation (EU) No 619/2011 of 24 June 2011 laying down the methods of sampling and analysis for the official control of feed as regards presence of genetically modified material for which an authorisation procedure is pending or the authorisation of which has expired Official Journal of the European Union 2011 L166 9 15
  4. [85]Directive 2001/18/EC of the European Parliament and of the Council of 12 March 2001 on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC Official Journal of the European Union 2001 L 106 1 38

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Authors
Broeders, S. R. M., De Keersmaecker, S. C. J., & Roosens, N. H. C.
Affiliations
  • Institut Scientifique de Santé Publique (BE)
  • Platform Biotechnology and Molecular Biology, Wetenschappelijk Instituut Volksgezondheid-Institut Scientifique de Santé Publique (WIV-ISP), J. Wytsmanstraat 14, 1050 Brussel, Belgium
Corresponding author
Roosens, Nancy H. C.
Venue
Journal of Biomedicine and Biotechnology
Published
2012
Volume
2012
Pages
1-11
ISSN
  • 1110-7243 (ISSN-L)
  • 1110-7251
OpenAlex
W2042949510
Cited by
85
References
64
Citations by year
2025: 3 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 4 · 2020: 11 · 2019: 7 · 2018: 4 · 2017: 10 · 2016: 12 · 2015: 12 · 2014: 7 · 2013: 3
FWCI
0.75
Type
journal article
Language
en
Open access
Locations
  • BioMed Research International (publishedVersion, cc-by)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Genetically Modified Organisms Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Identification and Quantification in Food
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Molecular Biology Techniques and Applications
Keywords
GMO detection, genetically modified organisms, food and feed, real-time PCR, GMO traceability, GMO labeling, GMO regulation, screening method
MeSH terms
Animals, Animal Feed, Genetic Techniques, Organisms, Genetically Modified, Food, Genetically Modified

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