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Cited by 135Mycotoxins in Agriculture and FoodMicrobial Natural Products and BiosynthesisPlant Pathogens and Fungal Diseases

Mycotoxins and Other Secondary Metabolites Produced in Vitro by Penicillium paneum Frisvad and Penicillium roqueforti Thom Isolated from Baled Grass Silage in Ireland

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O'Brien, Martin, Nielsen, Kristian F., O'Kiely, Padraig, Forristal, Patrick D., Fuller, Hubert T., Frisvad, Jens C.·2006·Journal of Agricultural and Food Chemistry
DOI 10.1021/jf0621018
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Abstract

Secondary metabolites produced by Penicillium paneum and Penicillium roqueforti from baled grass silage were analyzed. A total of 157 isolates were investigated, comprising 78 P. paneum and 79 P. roqueforti isolates randomly selected from more than 900 colonies cultured from bales. The findings mostly agreed with the literature, although some metabolites were not consistently produced by either fungus. Roquefortine C, marcfortine A, and andrastin A were consistently produced, whereas PR toxin and patulin were not. Five silage samples were screened for fungal metabolites, with two visually moldy samples containing up to 20 mg/kg of roquefortine C, mycophenolic acid, and andrastin A along with minor quantities (0.1-5 mg/kg) of roquefortines A, B, and D, festuclavine, marcfortine A, and agroclavine. Three visually nonmoldy samples contained low amounts of mycophenolic acid and andrastin A. The ability of both molds to produce a diverse range of secondary metabolites in vitro and in silage should be a concern to livestock producers.

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  • In maize silages, the most common potentially toxic moulds are Arthrinium phaeospermum, Aspergillus sp., Byssochlamys spp., Fusarium spp., Monascus ruber, and Penicillium spp.

    “Research on microflora of silages made of maize showed that the most common species of potentially toxic moulds are Arthrinium phaeospermum, Aspergillus sp., Byssochlamys spp., Fusarium spp., Monascus ruber and Penicillium spp. (O’Brien et al. 2006).”

    From Trends in designing microbial silage quality by biotechnological methods using lactic acid bacteria inoculants: a minireview. (2019) · cites this paper as O’Brien et al. 2006

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Authors
O'Brien, M., Nielsen, K. F., O'Kiely, P., Forristal, P. D., Fuller, H. T., & Frisvad, J. C.
Affiliations
  • Teagasc, Grange Beef Research Centre, Dunsany, Co. Meath, Ireland; Center for Microbial Biotechnology, BioCentrum-DTU, Technical University of Denmark, Building 221, DK-2800 Kgs. Lyngby, Denmark; Teagasc, Crops Research Centre, Oak Park, Co. Carlow, Ireland; and School of Biology and Environmental Science, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland
  • University College Dublin (IE)
ORCID
Venue
Journal of Agricultural and Food Chemistry
Publisher
American Chemical Society (ACS)
Published
2006-11-01
Volume
54
Issue
24
Pages
9268-9276
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
DOI
10.1021/jf0621018
OpenAlex
W2044286945
Cited by
135
References
23
Citations by year
2026: 3 · 2025: 6 · 2024: 7 · 2023: 5 · 2022: 6 · 2021: 5 · 2020: 9 · 2019: 6 · 2018: 5 · 2017: 8 · 2016: 9 · 2015: 11 · 2014: 6 · 2013: 12 · 2012: 5
FWCI
8.18
Type
journal article
Language
en
Open access
Licence
other-oa
Locations
  • Journal of Agricultural and Food Chemistry (publishedVersion)
  • PubMed (publishedVersion)
  • Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion, other-oa)
Funders
  • Teknologi og Produktion, Det Frie Forskningsråd
  • Teagasc
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
  • Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Plant Pathogens and Fungal Diseases
Keywords
Penicillium paneum, Penicillium roqueforti, mycotoxins, secondary metabolites, roquefortine C, mycophenolic acid, agroclavine, livestock feed safety
MeSH terms
Poaceae, Humans, Ireland, Mycotoxins, Penicillium, Silage, In Vitro Techniques

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