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Antioxidant Activity of Extracts from Du-zhong (Eucommia ulmoides) toward Various Lipid Peroxidation Models in Vitro

Yen, Gow-Chin, Hsieh, Chiu-Luan·1998·Journal of Agricultural and Food Chemistry

Abstract

The antioxidant effect of extracts from leaves, raw cortex, and roasted cortex of Du-zhong was evaluated using various lipid peroxidation models. The inhibitory activity of extracts of Du-zhong (200 μg/mL) on the peroxidation of linoleic acid measured by thiocyanate method followed the order leaves (99.9%) > roasted cortex (95.9%) > raw cortex (77.2%) at 60 h of incubation. The IC 20 for leaves, roasted cortex, and raw cortex on the peroxidation of liposome, induced by Fe 3+ /H 2 O 2 /ascorbic acid, was <0.06, 0.24, and 0.81 mg/mL, respectively. The thiobarbituric acid reactive substances values for leaves, roasted cortex, and raw cortex were 0.12, 1.54, and 1.81 μmol of malondialdehyde/mg of protein in enzyme-mediated microsomal peroxidation and 0.08, 0.69, and 0.88 μmol of malondialdehyde/mg of protein in the nonenzyme-mediated microsomal peroxidation, respectively. The antioxidant activity of extracts of Du-zhong correlates to their polyphenol content. The results presented herein indicate that extracts of Du-zhong leaves may be useful in inhibiting membrane lipid peroxidation and preventing free radical-linked disease. Keywords: Du-zhong tea; water extracts; antioxidant activity; lipid peroxidation; free radical

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Metadata

Authors
Yen, G.-C., & Hsieh, C.-L.
Venue
Journal of Agricultural and Food Chemistry
Published
1998-08-22
Volume
46
Issue
10
Pages
3952-3957
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W2054143299
Cited by
263
References
1
FWCI
0.93
Type
journal article
Language
en
Open access
closed

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