Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation

Coe, Jotham W., Brooks, Paige R., Vetelino, Michael G., Wirtz, Michael C., Arnold, Eric P., Huang, Jianhua, Sands, Steven B., Davis, Thomas I. +13 more·2005·Journal of Medicinal Chemistry

Cited by (960)

Items 201–300 of 960

  1. Transition Metal-Catalyzed Directed C(sp3)–H Functionalization of Saturated Heterocycles
    Daniele Antermite, James A. Bull · 2019 · Synthesis
  2. Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort
    Teresa R. Franklin, Ze Wang, Yin Li, Jesse J. Suh, Marina Goldman, Falk W. Lohoff, Jeffrey Cruz, Rebecca Hazan, William Jens, John A. Detre et al. · 2011 · Addiction Biology
  3. Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats
    Spiller, Krista, Xi, Zheng-Xiong, Li, Xia, Ashby, Charles R., Callahan, Patrick M., Tehim, Ashok, Gardner, Eliot L. · 2009 · Neuropharmacology
  4. Nicotinic receptor modulation to treat alcohol and drug dependence
    Shafiqur Rahman, Eric A. Engleman, Richard L. Bell · 2015 · Frontiers in Neuroscience
  5. Nicotinic receptor ligands reduce ethanol intake by high alcohol–drinking HAD-2 rats
    Richard L. Bell, Bill J.A. Eiler, Jason B. Cook, Shafiqur Rahman · 2009 · Alcohol
  6. Functional Interactions of Fibrillar and Oligomeric Amyloid-β with Alpha7 Nicotinic Receptors in Alzheimer's Disease
    Lilja, Anna M., Porras, Omar, Storelli, Elisa, Nordberg, Agneta, Marutle, Amelia · 2011 · Journal of Alzheimer's Disease
  7. Nicotine Dependence: Biology, Behavior, and Treatment
    Riju Ray, Robert A. Schnoll, Caryn E. Lerman · 2009 · Annual Review of Medicine
  8. Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists
    François Crestey, Anders A. Jensen, Morten Borch, Jesper Tobias Andreasen, Jacob Andersen, Thomas Balle, Jesper Langgaard Kristensen · 2013 · Journal of Medicinal Chemistry
  9. Novel Pharmacological Approaches for Treating Tobacco Dependence and Withdrawal
    August R. Buchhalter, Reginald V. Fant, Jack E. Henningfield · 2008 · Drugs
  10. Pharmacotherapy of smoking cessation
    Ram Chander Jiloha · 2014 · Indian Journal of Psychiatry
  11. Nicotinic receptor-based therapeutics and candidates for smoking cessation
    Linda P. Dwoskin, Andrew M. Smith, Thomas E. Wooters, Zhenfa Zhang, Peter Anthony Crooks, Michael Thomas Bardo · 2009 · Biochemical Pharmacology
  12. Recent Developments in Novel Antidepressants Targeting α4β2-Nicotinic Acetylcholine Receptors
    Li-Fang Yu, Han-Kun Zhang, Barbara J. Caldarone, Jason Brek Eaton, Ronald J. Lukas, Alan P. Kozikowski · 2014 · Journal of Medicinal Chemistry
  13. An inhibitory brainstem input to dopamine neurons encodes nicotine aversion
    Christine Junhui Liu, Amanda J. Tose, Jeroen P. H. Verharen, Yichen Zhu, Lilly W. Tang, Johannes W. de Jong, Jessica X. Du, Kevin T. Beier, Stephan Lammel · 2022 · Neuron
  14. Varenicline-Induced Mixed Mood and Psychotic Episode in a Patient with a Past History of Depression
    Andres Julio Pumariega, Robert Nelson, Larry A. Rotenberg · 2008 · CNS Spectrums
  15. Targeting α4β2 Nicotinic Acetylcholine Receptors in Central Nervous System Disorders: Perspectives on Positive Allosteric Modulation as a Therapeutic Approach
    Morten Grupe, Morten Grunnet, Jesper F. Bastlund, Anders A. Jensen · 2014 · Basic & Clinical Pharmacology & Toxicology
  16. Pharmacogenetics of Nicotine Addiction: Role of Dopamine
    Aryeh I. Herman, Elise E. DeVito, Kevin P. Jensen, Mehmet Sofuoglu · 2014 · Pharmacogenomics
  17. Nicotinic Receptor Antagonists as Treatments for Nicotine Abuse
    Peter Anthony Crooks, Michael Thomas Bardo, Linda P. Dwoskin · 2014 · Advances in pharmacology
  18. PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans
    Ansel T. Hillmer, Songye Li, Ming‐Qiang Zheng, Matthias Scheunemann, Shu-fei Lin, Nabeel Nabulsi, Daniel Holden, Richard Pracitto, David C. Labaree, Jim R. Ropchan et al. · 2017 · European Journal of Nuclear Medicine and Molecular Imaging
  19. Catalytic Enantioselective Pyridine N -Oxidation
    Sheng‐Ying Hsieh, Yu Tang, Simone Crotti, Elizabeth A. Stone, Scott J. Miller · 2019 · Journal of the American Chemical Society
  20. Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use
    Lauren C. Smith, Marsida Kallupi, Lani Tieu, Kokila Shankar, Abigail A. Jaquish, Jamie Barr, Yujuan Su, Nathan Velarde, Sharona Sedighim, Lieselot L. G. Carrette et al. · 2020 · Neuropsychopharmacology
  21. Neurophysiology of Nicotine Addiction
    John A. Dani, Daniel Jenson, John I. Broussard · 2012 · Journal of Addiction Research & Therapy
  22. Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors
    Barbara G. Campling, Alexander Kuryatov, Jon Martin Lindstrom · 2013 · PLoS ONE
  23. Synthesis and Characterization of Nitroaromatic Peptoids: Fine Tuning Peptoid Secondary Structure through Monomer Position and Functionality
    Sarah A. Fowler, Rinrada Luechapanichkul, Helen E. Blackwell · 2009 · The Journal of Organic Chemistry
  24. Pharmacokinetics, Safety, and Tolerability After Single and Multiple Oral Doses of Varenicline in Elderly Smokers
    Aaron H. Burstein, Terence Fullerton, David J. Clark, Hélène M. Faessel · 2006 · The Journal of Clinical Pharmacology
  25. Concise Synthesis of (±)-Cytisine via Lithiation of N-Boc-bispidine
    Darren Stead, Peter O’Brien, Adam J. Sanderson · 2005 · Organic Letters
  26. Functional Probes of Drug–Receptor Interactions Implicated by Structural Studies: Cys-Loop Receptors Provide a Fertile Testing Ground
    Ethan B. Van Arnam, Dennis A. Dougherty · 2014 · Journal of Medicinal Chemistry
  27. Pharmacological Characterization of the Allosteric Modulator Desformylflustrabromine and Its Interaction with α4β2 Neuronal Nicotinic Acetylcholine Receptor Orthosteric Ligands
    Maegan M. Weltzin, Marvin K. Schulte · 2010 · Journal of Pharmacology and Experimental Therapeutics
  28. A randomized controlled open comparative trial of varenicline vs nicotine patch in adult smokers: efficacy, safety and withdrawal symptoms (the VN-SEESAW study)
    Tsukahara, Hitomi, Noda, Keita, Saku, Keijiro · 2010 · Circulation Journal
  29. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties
    Mineur, Yann S., Einstein, Emily B., Seymour, Patricia A., Coe, Jotham W., O'Neill, Brian T., Rollema, Hans, Picciotto, Marina R. · 2011 · Behavioural Pharmacology
  30. South African tobacco smoking cessation clinical practice guideline
    Richard Nellis van Zyl-Smit, Brian Allwood, David Stickells, Gregory Symons, Sabs Abdool-Gaffar, Kathy Murphy, Umesh Lalloo, Aneesa Vanker, Keertan U.J. Dheda, Guy Antony Richards · 2013 · South African Medical Journal
  31. A Rat Drinking in the Dark Model for Studying Ethanol and Sucrose Consumption
    Joan Y. Holgate, Masroor R. Shariff, Erica W. H. Mu, Selena E. Bartlett · 2017 · Frontiers in Behavioral Neuroscience
  32. Varenicline
    Gillian M. Keating, M Asif A Siddiqui · 2006 · CNS Drugs
  33. Varenicline for smoking cessation: nausea severity and variation in nicotinic receptor genes
    Gary E. Swan, Harold S. Javitz, Lisa M. Jack, Jennifer Wessel, M Michel, David A. Hinds, R P Stokowksi, Jennifer B. McClure, Sheryl L. Catz, Julie Angerhofer Richards et al. · 2011 · The Pharmacogenomics Journal
  34. Multiple CNS nicotinic receptors mediate l-dopa-induced dyskinesias: Studies with parkinsonian nicotinic receptor knockout mice
    Maryka Quik, Carla Campos, Sharon R. Grady · 2013 · Biochemical Pharmacology
  35. Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors through Study of Ligand Complexes with Acetylcholine-binding Protein
    Prakash Rucktooa, Claire A. Haseler, René van Elk, August Benjamin Smit, Timothy C. Gallagher, Titia K. Sixma · 2012 · Journal of Biological Chemistry
  36. Nicotinic Receptor Agonists Reduce l-DOPA–Induced Dyskinesias in a Monkey Model of Parkinson's Disease
    Danhui Zhang, Archana Mallela, David Sohn, Frank Ivy Carroll, Merouane Bencherif, Sharon R. Letchworth, Maryka Quik · 2013 · Journal of Pharmacology and Experimental Therapeutics
  37. Patterns of Nicotinic Receptor Antagonism: Nicotine Discrimination Studies
    Emily M. Jutkiewicz, Emily A. Brooks, Adam D. Kynaston, Kenner C. Rice, James Henry Woods · 2011 · Journal of Pharmacology and Experimental Therapeutics
  38. Cytisine Therapy Improved Smoking Cessation in the Randomized Screening and Multiple Intervention on Lung Epidemics Lung Cancer Screening Trial
    Ugo Pastorino, Vito Ladisa, Sara Trussardo, Federica Sabia, Luigi Rolli, Camilla Valsecchi, Roberta Eufrasia Ledda, Gianluca Milanese, Paola Suatoni, Mattia Boeri et al. · 2022 · Journal of Thoracic Oncology
  39. Identification of Novel α4β2-Nicotinic Acetylcholine Receptor (nAChR) Agonists Based on an Isoxazole Ether Scaffold that Demonstrate Antidepressant-like Activity
    Li-Fang Yu, Werner Tückmantel, Jason Brek Eaton, Barbara J. Caldarone, Allison Fedolak, Taleen Hanania, Dani Brunner, Ronald J. Lukas, Alan P. Kozikowski · 2011 · Journal of Medicinal Chemistry
  40. Prenatal tobacco prevention and cessation interventions for women in low‐ and middle‐income countries
    Cheryl A. Oncken, Patricia M. Dietz, Van T. Tong, José Miguel Belizán, Jorge E. Tolosa, Vincenzo Berghella, Robert L. Goldenberg, Harry Alan Lando, Jonathan M. Samet, Michele Bloch · 2010 · Acta Obstetricia Et Gynecologica Scandinavica
  41. Galantamine reduces smoking in alcohol-dependent patients: a randomized, placebo-controlled trial
    Alexander Diehl, Helmut Nakovics, Bernhard Croissant, Michael N. Smolka, Anil Batra, Karl F Mann · 2006 · International Journal of Clinical Pharmacology and Therapeutics
  42. Varenicline
    RAYMOND S. NIAURA, Carole Jones, Peter N. Kirkpatrick · 2006 · Nature Reviews Drug Discovery
  43. Nicotine receptor partial agonists for smoking cessation
    Cahill, Kate, Stead, Lindsay F, Lancaster, Tim · 2010 · Cochrane Database of Systematic Reviews
  44. Lobeline and cytisine reduce voluntary ethanol drinking behavior in male C57BL/6J mice
    Ravi Kiran Sajja, Shafiqur Rahman · 2010 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  45. Varenicline, low dose naltrexone, and their combination for heavy-drinking smokers: human laboratory findings
    Lara A. Ray, Kelly Elizabeth Courtney, Dara G. Ghahremani, Karen A. Miotto, Arthur L. Brody, Edythe D. London · 2014 · Psychopharmacology
  46. Diversity-oriented synthesis of a cytisine-inspired pyridone library leading to the discovery of novel inhibitors of Bcl-2
    Lisa A. Marcaurelle, Charles William Johannes, Daniel Yohannes, Bonnie P. Tillotson, David Mann · 2009 · Bioorganic & Medicinal Chemistry Letters
  47. Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation
    Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja A. Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye · 2023 · Health Psychology Research
  48. Varenicline Potentiates Alcohol‐Induced Negative Subjective Responses and Offsets Impaired Eye Movements
    Emma Childs, Daniel J. O. Roche, Andrea C. King, Harriet de Wit · 2012 · Alcoholism Clinical and Experimental Research
  49. Pharmacologically Distinct Nicotinic Acetylcholine Receptors Drive Efferent-Mediated Excitation in Calyx-Bearing Vestibular Afferents
    Joseph C. Holt, Kevin Kewin, Paivi M. Jordan, Peter Alistair Cameron, Marcin Klapczynski, J. Michael McIntosh, Peter Anthony Crooks, Linda P. Dwoskin, Anna Lysakowski · 2015 · Journal of Neuroscience
  50. Mechanisms of Inhibition and Potentiation of α4β2 Nicotinic Acetylcholine Receptors by Members of the Ly6 Protein Family
    Meilin Wu, Clare A. Puddifoot, Palmer Taylor, William J. Joiner · 2015 · Journal of Biological Chemistry
  51. Synthesis, Binding, and Modeling Studies of New Cytisine Derivatives, as Ligands for Neuronal Nicotinic Acetylcholine Receptor Subtypes
    Bruno Tasso, Caterina Canu Boido, Emanuela Terranova, Cecilia Gotti, Loredana Riganti, Francesco Clementi, Roberto Artali, G. Bombieri, Fiorella Meneghetti, Fabio Sparatore · 2009 · Journal of Medicinal Chemistry
  52. The Effects of Extended Pre-Quit Varenicline Treatment on Smoking Behavior and Short-Term Abstinence: A Randomized Clinical Trial
    Larry W. Hawk, Rebecca L. Ashare, S F Lohnes, Nicolas J. Schlienz, Jessica D. Rhodes, Stephen T. Tiffany, Julie C. Gass, K. Michael Cummings, Martin Christopher Mahoney · 2011 · Clinical Pharmacology & Therapeutics
  53. Oral Varenicline for Smoking Cessation
    Seena Zierler-Brown, Jeffrey A. Kyle · 2006 · Annals of Pharmacotherapy
  54. Pharmacogenetic Optimization of Smoking Cessation Treatment
    Meghan J. Chenoweth, Rachel Fynvola Tyndale · 2016 · Trends in Pharmacological Sciences
  55. Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity α4β2 subunit combination
    Anderson, David J., Malysz, John, Grønlien, Jens Halvard, El Kouhen, Rachid, Håkerud, Monika, Wetterstrand, Caroline, Briggs, Clark A., Gopalakrishnan, Murali · 2009 · Biochemical Pharmacology
  56. Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history
    Robert W. Gould, Pradeep Garg, Sudha Garg, Michael A. Nader · 2012 · Neuropharmacology
  57. Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines
    Victor I. Reus, B. J. Smith · 2008 · International Journal of Clinical Practice
  58. Cardiovascular Safety of Varenicline
    James H. Ware, George Wayne Vetrovec, Alan Bruce Miller, Andrew Van Tosh, Michael Gaffney, Carla Yunis, Carmen Arteaga, JEFFREY S. BORER · 2013 · American Journal of Therapeutics
  59. The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development
    Noah S. Philip, Linda L. Carpenter, Audrey R. Tyrka, Lawrence H. Price · 2012 · The Scientific World JOURNAL
  60. Medicinal Chemistry for 2020
    Seetharama D. Satyanarayanajois, Ronald A. Hill · 2011 · Future Medicinal Chemistry
  61. An Employer-Based Cost-Benefit Analysis of a Novel Pharmacotherapy Agent for Smoking Cessation
    Kenneth C. Jackson, Robert Nahoopii, Qayyim Said, Riad D Dirani, Diana I Brixner · 2007 · Journal of Occupational and Environmental Medicine
  62. Emerging drugs for the treatment of tobacco dependence: 2014 update
    Muhamad Y. Elrashidi, Jon O. Ebbert · 2014 · Expert Opinion on Emerging Drugs
  63. Brain Nicotinic Acetylcholine Receptor Availability and Response to Smoking Cessation Treatment
    Arthur L. Brody, Alexey G. Mukhin, Michael S Mamoun, Trinh Luu, Meaghan K. Neary, Lidia Liang, Jennifer Shieh, Catherine A. Sugar, Jed E. Rose, Mark A. Mandelkern · 2014 · JAMA Psychiatry
  64. Combination bupropion SR and varenicline for smoking cessation: a systematic review
    Tiffany Vogeler, Claire A. McClain, Kirk E. Evoy · 2016 · The American Journal of Drug and Alcohol Abuse
  65. Varenicline for smoking cessation: a narrative review of efficacy, adverse effects, use in at-risk populations, and adherence
    Jon O. Ebbert, Michael V. Burke, James Taylor Hays · 2016 · Patient Preference and Adherence
  66. Mechanism-based medication development for the treatment of nicotine dependence
    Zheng‐Xiong Xi, Krista J. Spiller, Eliot L. Gardner · 2009 · Acta Pharmacologica Sinica
  67. Negative Allosteric Modulation of Nicotinic Acetylcholine Receptors Blocks Nicotine Self-Administration in Rats
    Ryan F. Yoshimura, Derk J. Hogenkamp, Wen Y. Li, Minhtam B. Tran, James D. Belluzzi, Edward R. Whittemore, Frances M. Leslie, Kelvin W. Gee · 2007 · Journal of Pharmacology and Experimental Therapeutics
  68. Intramolecular 1,6-Addition to 2-Pyridones. Mechanism and Synthetic Scope.
    Timothy C. Gallagher, Ian Derrick, Patrick Durkin, Claire A. Haseler, Christoph Hirschhäuser, Pietro Magrone · 2010 · The Journal of Organic Chemistry
  69. Effect of the α4β2∗ nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in β2 knock-out mice with selective re-expression of the β2 subunit in the ventral tegmental area
    Christelle Repérant, Stéphanie Pons, Eric Dufour, Hans Rollema, Alain Michel Gardier, Uwe Maskos · 2009 · Neuropharmacology
  70. Effects of varenicline and bupropion on cognitive processes among nicotine-deprived smokers.
    Rebecca L. Ashare, Sherry A. McKee · 2011 · Experimental and Clinical Psychopharmacology
  71. Dopamine D3 Receptor Heteromerization: Implications for Neuroplasticity and Neuroprotection
    Federica Bono, Veronica Mutti, Chiara Fiorentini, Cristina Missale · 2020 · Biomolecules
  72. Varenicline: The newest agent for smoking cessation
    Lisa A. Potts, Candice L. Garwood · 2007 · American Journal of Health-System Pharmacy
  73. What do we know about the role of pharmacotherapy for smoking cessation before or during pregnancy?
    Cheryl A. Oncken, Henry R. Kranzler · 2009 · Nicotine & Tobacco Research
  74. Total synthesis of the lupin alkaloid cytisine: comparison of synthetic strategies and routes
    Darren Stead, Peter O’Brien · 2006 · Tetrahedron
  75. Recommendations for the Use of Pharmacological Smoking Cessation Strategies in Pregnant Women
    Tim J Coleman · 2007 · CNS Drugs
  76. Promoting smoking cessation
    Michele Larzelere, Dave E. Williams · 2005 · BDJ
  77. Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation
    Darlene H. Brunzell, J. Michael McIntosh, Roger L. Papke · 2014 · Annals of the New York Academy of Sciences
  78. Therapeutic advances in the treatment of nicotine addiction: present and future
    Giuseppina Casella, Pasquale Caponnetto, Riccardo Polosa · 2010 · Therapeutic Advances in Chronic Disease
  79. Treating Tobacco Dependence in Light of the 2008 US Department of Health and Human Services Clinical Practice Guideline
    James Taylor Hays, Jon O. Ebbert, Amit Sood · 2009 · Mayo Clinic Proceedings
  80. Neuropharmacology of the Interoceptive Stimulus Properties of Nicotine
    Thomas E. Wooters, Rick A. Bevins, Michael Thomas Bardo · 2009 · Current Drug Abuse Reviews
  81. Variations in Binding Among Several Agonists at Two Stoichiometries of the Neuronal, α4β2 Nicotinic Receptor
    Ximena Da Silva Tavares, Angela P. Blum, Darren T. Nakamura, Nyssa L. Puskar, Jai A. P. Shanata, Henry A. Lester, Dennis A. Dougherty · 2012 · Journal of the American Chemical Society
  82. The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens
    Shafiqur Rahman, Nichole M. Neugebauer‎, Zhenfa Zhang, Peter Anthony Crooks, Linda P. Dwoskin, Michael Thomas Bardo · 2006 · Neuropharmacology
  83. Human Abuse Liability of the Smoking Cessation Drug Varenicline in Smokers and Nonsmokers
    Shelley L. McColl, AH Burstein, K. R. Reeves, CB Billing, Marilyn J. Stolar, Edward M. Sellers · 2008 · Clinical Pharmacology & Therapeutics
  84. Unlocking Nicotinic Selectivity via Direct C‒H Functionalization of (−)-Cytisine
    Hugo Rego Campello, Silvia G. del Villar, Aurélien Honraedt, Teresa Minguez, A. Sofia F. Oliveira, Kara E. Ranaghan, Deborah K. Shoemark, Isabel Bermúdez, Cecilia Gotti, Richard Barry Sessions et al. · 2018 · Chem
  85. Dopamine D3receptor ligands for the treatment of tobacco dependence
    Bernard Le Foll, Steven R. Goldberg, Pierre Sokoloff · 2006 · Expert Opinion on Investigational Drugs
  86. Bupropion inhibits the cellular effects of nicotine in the ventral tegmental area
    Huibert D. Mansvelder, Zara M. Fagen, Ben Chang, Robert D. Mitchum, Daniel S. McGehee · 2007 · Biochemical Pharmacology
  87. Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse
    Candice E. Van Skike, Sarah E. Maggio, Anna R. Reynolds, Erin M. Casey, Michael Thomas Bardo, Linda P. Dwoskin, Mark Prendergast, Kimberly Nixon · 2015 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  88. Varenicline: A Selective α4β2 Nicotinic Acetylcholine Receptor Partial Agonist Approved for Smoking Cessation
    Sum Lam, Priti N. Patel · 2007 · Cardiology in Review
  89. Impacts of a Smoking Cessation Benefit Among Employed Populations
    Michael T. Halpern, Riad D Dirani, Jordana K. Schmier · 2007 · Journal of Occupational and Environmental Medicine
  90. Solvent-free double aza-Michael under ultrasound irradiation: diastereoselective sequential one-pot synthesis of pyrrolidine Lobelia alkaloids analogues
    Zacharias Amara, Emmanuelle Drège, Claire Troufflard, Pascal Retailleau, Delphine Joseph · 2012 · Organic & Biomolecular Chemistry
  91. The efficacy and safety of a nicotine conjugate vaccine (NicVAX®) or placebo co-administered with varenicline (Champix®) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial
    Philippe Hoogsteder, Daniel Kotz, P.I. van Spiegel, Wolfgang Viechtbauer, Ruth Brauer, Paul Kessler, Matthew W. Kalnik, Raafat E.F. Fahim, Onno C. P. van Schayck · 2012 · BMC Public Health
  92. The contribution of agonist and antagonist activities of α4β2* nAChR ligands to smoking cessation efficacy: a quantitative analysis of literature data
    Hans Rollema, Raymond S Hurst · 2018 · Psychopharmacology
  93. Smoking Cessation
    Michael A. Chandler, Stephen I. Rennard · 2010 · CHEST Journal
  94. A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial)
    Mitchell A. Nides, Nancy A. Rigotti, Neal L. Benowitz, Anthony Clarke, Cindy A. Jacobs · 2021 · Nicotine & Tobacco Research
  95. Tobacco smoking cessation management: integrating varenicline in current practice
    Laurence M Galanti · 2008 · Vascular Health and Risk Management
  96. The Nicotinic Acetylcholine Receptor Partial Agonist Varenicline Increases the Ataxic and Sedative‐Hypnotic Effects of Acute Ethanol Administration in C57BL/6J Mice
    Helen M. Kamens, Jimena Andersen, Marina R. Picciotto · 2010 · Alcoholism Clinical and Experimental Research
  97. Reward Anticipation Is Differentially Modulated by Varenicline and Nicotine in Smokers
    John R. Fedota, Matthew T. Sutherland, Betty Jo Salmeron, Thomas J. Ross, Liyi Elliot Hong, Elliot A. Stein · 2015 · Neuropsychopharmacology
  98. The Effects of Varenicline on Alcohol Seeking and Self-Administration in Baboons
    Barbara J. Kaminski, Elise M. Weerts · 2013 · Alcoholism Clinical and Experimental Research
  99. Effects of Varenicline on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rhesus Monkeys
    Robert W. Gould, Paul W. Czoty, Susan H. Nader, Michael A. Nader · 2011 · Journal of Pharmacology and Experimental Therapeutics
  100. Development of Novel Pharmacotherapeutics for Tobacco Dependence: Progress and Future Directions
    Dympna Harmey, Patrick R. Griffin, Paul J. Kenny · 2012 · Nicotine & Tobacco Research